Medical College of Wisconsin
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Development of neuron-neuron synapses. Curr Opin Neurobiol 2000 Feb;10(1):125-31

Date

02/19/2000

Pubmed ID

10679427

DOI

10.1016/s0959-4388(99)00046-x

Scopus ID

2-s2.0-0033964412 (requires institutional sign-in at Scopus site)   94 Citations

Abstract

Our understanding of neuronal synapse development has advanced in recent years. The development of glycinergic synapses appears to depend on gephyrin and glycine receptor activity. Molecular characterization of the structure and development of glutamatergic synapses is in progress, but the underlying mechanisms remain unclear. Activity-dependent mechanisms and specific molecules that regulate the morphological development of dendritic spines have recently been identified.

Author List

Lee SH, Sheng M

Author

Sang H. Lee PhD Professor in the Pharmacology and Toxicology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Dendrites
Humans
Motor Endplate
Nerve Growth Factors
Nerve Tissue Proteins
Nervous System
Neurons
Receptors, Glutamate
Synapses