Faculty Collaboration Database

Multilocular renal cyst: electron microscopic evidence of pathogenesis. Am J Pediatr Hematol Oncol 1984;6(1):27-32

Date

01/01/1984

Pubmed ID

6324606

Scopus ID

2-s2.0-0021230173 (requires institutional sign-in at Scopus site)   15 Citations

Abstract

Two cases of multilocular renal cyst (MRC) are presented with electron microscopic findings. The epithelial cells of the cysts resembled renal collecting tubule cells and not convoluted tubule or Henle's loop cells. Intercystic areas contained only connective tissue elements. Simple MRC appears to be a congenital malformation that results from segmental maldevelopment of the ureteric bud. In some cases of MRC, the intercystic septa contain immature renal elements. The lesion is then called cystic poorly differentiated nephroblastoma (CPDN). However, in both MRC and CPDN, local recurrence or metastases have not been described. Treatment of these lesions should consist of nephrectomy, careful histologic evaluation to rule out obvious foci of Wilms' tumor, and conservative follow-up.

Author List

Tang TT, Harb JM, Oechler HW, Camitta BM

Author

Bruce m. Camitta Professor in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Diagnosis, Differential
Female
Humans
Infant
Kidney
Kidney Diseases, Cystic
Kidney Neoplasms
Male
Microscopy, Electron
Nephrectomy
Wilms Tumor