Cardiac transplantation for pediatric giant cell myocarditis. J Heart Lung Transplant 2006 Apr;25(4):474-8
Date
03/28/2006Pubmed ID
16563980DOI
10.1016/j.healun.2005.11.444Scopus ID
2-s2.0-33645049103 (requires institutional sign-in at Scopus site) 21 CitationsAbstract
Giant cell myocarditis (GCM) is an organ-specific, autoimmune disease that infrequently affects children and generally has a more aggressive (often fatal) course than other forms of myocarditis. No data are available about the epidemiology of GCM in children. We describe a 13-year-old girl who presented with ventricular tachycardia and rapid hemodynamic deterioration that required extracorporeal membrane oxygenation (ECMO) as a bridge to heart transplantation. Histopathologic examination of the explanted heart revealed GCM. We review the demographic features, clinical course and post-transplant immunosuppressive therapy of all patients aged 19 years and younger reported to have had GCM.
Author List
Das BB, Recto M, Johnsrude C, Klein L, Orman K, Shoemaker L, Mitchell M, Austin EHAuthor
Michael Edward Mitchell MD Chief, Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAge Factors
Extracorporeal Membrane Oxygenation
Female
Giant Cells
Heart Transplantation
Humans
Immunosuppressive Agents
Myocarditis
Preoperative Care
Tachycardia, Ventricular
