Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Thyroid carcinoma following treatment for acute lymphoblastic leukemia. Cancer 1980 Oct 01;46(7):1572-6

Date

10/01/1980

Pubmed ID

6932254

DOI

10.1002/1097-0142(19801001)46:7<1572::aid-cncr2820460713>3.0.co;2-2

Scopus ID

2-s2.0-0018959272 (requires institutional sign-in at Scopus site)   21 Citations

Abstract

A 2 1/2-year-old girl with acute lymphoblastic leukemia received chemotherapy and prophylactic cranial irradiation. After six years of remission, including three years off therapy, metastatic thyroid carcinoma appeared in the cervical lymph nodes. The predisposing factors for the development of thyroid carcinoma as a second malignancy in this case are discussed. It is suggested that thyroid carcinoma should be added to the growing list of second malignancies in acute lymphoblastic leukemia and that careful thyroid examination be included in the follow-up of long-term survivors.

Author List

Tang TT, Holcenberg JS, Duck SC, Hodach AE, Oechler HW, Camitta BM

Author

Bruce m. Camitta Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Antineoplastic Agents
Carcinoma
Child, Preschool
Dose-Response Relationship, Radiation
Female
Humans
Leukemia, Lymphoid
Neoplasms, Radiation-Induced
Radiotherapy
Risk
Thyroid Neoplasms