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Comparison of six commercial plasma references for factor VIII, factor IX and von Willebrand factor. On behalf of the Subcommittee for Factor VIII and IX of the Scientific and Standardization Committee of the ISTH. Thromb Haemost 1995 Sep;74(3):987-9

Date

09/01/1995

Pubmed ID

8571334

DOI

10.1055/s-0038-1649860

Scopus ID

2-s2.0-0029082911 (requires institutional sign-in at Scopus site)   7 Citations

Abstract

Six brands of normal reference plasma produced in the United States, with assigned assay values for factor VII and IX and, in four instances, ristocetin cofactor and van Willebrand antigen, were assayed in nine coagulation laboratories in academic institutions in the same country. Differences in mean assays of reference plasmas, as a percent of labelled potency, were significant and were greater than differences among laboratories. Standard methods of assigning potency to commercial reference plasmas are recommended.

Author List

Kasper CK, Aronson DL, Davignon G, Foster P, Hillman-Wiseman C, Lusher JM, Manco-Johnson M, Meade JB, Montgomery RR, Rickles FR

Author

Robert R. Montgomery MD Emeritus Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Antigens
Factor IX
Factor VIII
Humans
Reference Standards
Ristocetin
United States
von Willebrand Factor