Faculty Collaboration Database

A history of alcohol dependence increases the incidence and severity of postoperative cognitive dysfunction in cardiac surgical patients. Int J Environ Res Public Health 2009 Nov;6(11):2725-39

Date

01/06/2010

Pubmed ID

20049218

Pubmed Central ID

PMC2800057

DOI

10.3390/ijerph6112725

Scopus ID

2-s2.0-73449101823 (requires institutional sign-in at Scopus site)   24 Citations

Abstract

Postoperative cognitive dysfunction (POCD) commonly occurs after cardiac surgery. We tested the hypothesis that a history of alcohol dependence is associated with an increased incidence and severity of POCD in male patients undergoing cardiac surgery using cardiopulmonary bypass. Recent verbal and nonverbal memory and executive functions were assessed before and one week after surgery in patients with or without a history of alcohol dependence. Cognitive function was significantly reduced after cardiac surgery in patients with versus without a history of alcohol dependence. The results suggest that a history of alcohol dependence increases the incidence and severity of POCD after cardiac surgery.

Author List

Hudetz JA, Patterson KM, Byrne AJ, Iqbal Z, Gandhi SD, Warltier DC, Pagel PS

Authors

Sweeta D. Gandhi MD Associate Professor in the Anesthesiology department at Medical College of Wisconsin
Paul S. Pagel PhD, MS, MD Emeritus Professor in the Anesthesiology department at Medical College of Wisconsin
David C. Warltier PhD Emeritus Professor in the Anesthesiology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Aged
Alcoholism
Cardiopulmonary Bypass
Case-Control Studies
Cognition Disorders
Humans
Incidence
Logistic Models
Male
Multivariate Analysis
Neuropsychological Tests
Postoperative Complications
Prospective Studies
Psychometrics
Risk Assessment
Severity of Illness Index
Time Factors
United States
Wisconsin