Medical College of Wisconsin
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Hematopoietic stem cell transplantation for severe aplastic anemia. Curr Opin Hematol 1998 Nov;5(6):441-4

Date

11/14/1998

Pubmed ID

9814653

DOI

10.1097/00062752-199811000-00015

Scopus ID

2-s2.0-0031593816 (requires institutional sign-in at Scopus site)   2 Citations

Abstract

Severe aplastic anemia (SAA) appears to be an immunologically mediated disorder that results in deficient and defective hematopoietic stem cells. Both immune suppression and hematopoietic stem cell transplantation provide effective treatment for SAA. Optimal choice between these therapies depends upon a complex interaction of patient age, disease severity, overall patient health, and donor availability. Recent publications provide additional information on the long-term efficacy and toxicity of both treatments. Prospective studies with long-term follow-up are needed to put these and newer treatments in proper perspective.

Author List

Margolis DA, Cammita BM

Author

David A. Margolis BA, MD Chair, Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Anemia, Aplastic
Blood Donors
Hematopoietic Stem Cell Transplantation
Humans
Survival Rate