Lung redox homeostasis: emerging concepts. Am J Physiol Lung Cell Mol Physiol 2000 Sep;279(3):L413-7
Date
08/25/2000Pubmed ID
10956613DOI
10.1152/ajplung.2000.279.3.L413Scopus ID
2-s2.0-0033833762 (requires institutional sign-in at Scopus site) 15 CitationsAbstract
This symposium was organized to present some aspects of current research pertaining to lung redox function. Focuses of the symposium were on roles of pulmonary endothelial NADPH oxidase, xanthine oxidase (XO)/xanthine dehydrogenase (XDH), heme oxygenase (HO), transplasma membrane electron transport (TPMET), and the zinc binding protein metallothionein (MT) in the propagation and/or protection of the lung or other organs from oxidative injury. The presentations were chosen to reflect the roles of both intracellular (metallothionein, XO/XDH, and HO) and plasma membrane (NADPH oxidase, XO/XDH, and unidentified TPMET) redox proteins in these processes. Although the lung endothelium was the predominant cell type under consideration, at least some of the proposed mechanisms operate in or affect other cell types and organs as well.
Author List
Merker MP, Pitt BR, Choi AM, Hassoun PM, Dawson CA, Fisher ABMESH terms used to index this publication - Major topics in bold
AnimalsEndothelium, Vascular
Homeostasis
Lung
Oxidation-Reduction
Oxidative Stress
Pulmonary Circulation
