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Endovascular therapy for chronic cerebrospinal venous insufficiency in multiple sclerosis. Front Neurol 2011;2:44

Date

08/03/2011

Pubmed ID

21808631

Pubmed Central ID

PMC3139170

DOI

10.3389/fneur.2011.00044

Scopus ID

2-s2.0-84865780253 (requires institutional sign-in at Scopus site)   3 Citations

Abstract

Recent reports have emerged suggesting that multiple sclerosis (MS) may be due to abnormal venous outflow from the central nervous system, termed chronic cerebrospinal venous insufficiency (CCSVI). These reports have generated strong interest and controversy over the prospect of a treatable cause of this chronic debilitating disease. This review aims to describe the proposed association between CCSVI and MS, summarize the current data, and discuss the role of endovascular therapy and the need for rigorous randomized clinical trials to evaluate this association and treatment.

Author List

Lazzaro MA, Zaidat OO, Mueller-Kronast N, Taqi MA, Woo D

Author

Marc A. Lazzaro MD Associate Professor in the Neurology department at Medical College of Wisconsin