Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Effect of ovariectomy on magnetic resonance T2* in rat femur. Magn Reson Med 1996 Oct;36(4):567-70

Date

10/01/1996

Pubmed ID

8892209

DOI

10.1002/mrm.1910360411

Scopus ID

2-s2.0-0029782866 (requires institutional sign-in at Scopus site)   3 Citations

Abstract

Measurements have been made in the rat femur in vivo and ex vivo by using an asymmetric spin echo technique of T2(1), the susceptibility contribution to T2*. The trabecular spacing in this study in rat bone is considerably less than in previous studies in the human. A significant increase in T2(1) was seen in vivo 3 mm proximal to the growth plate with ovariectomy (a model of osteopenia), from 8.1 +/- 0.7 to 10.0 +/- 0.6 ms. Parallel changes in trabecular bone mineral density measured by quantitative computed tomography were found. T2(1) was higher in living bones than in the same bones measured post mortem.

Author List

Checkley D, Millest AJ, Johnstone D, Waterton JC

Author

David Johnstone MD Emeritus Professor in the Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Absorptiometry, Photon
Animals
Bone Density
Bone Diseases, Metabolic
Female
Femur
Magnetic Resonance Spectroscopy
Ovariectomy
Rats