Gastrointestinal stromal tumor surgery and adjuvant therapy. Surg Clin North Am 2011 Oct;91(5):1079-87
Date
09/06/2011Pubmed ID
21889030DOI
10.1016/j.suc.2011.06.007Scopus ID
2-s2.0-80052235397 (requires institutional sign-in at Scopus site) 28 CitationsAbstract
Gastrointestinal stromal tumors (GIST) are a unique class of mesenchymal tumors identified within the past decade. Intense molecular and genetic study has been used to characterize these tumors and develop treatment strategies. Although the mainstay of treatment remains surgical resection, therapy targeted at inhibiting tyrosine kinases has had dramatic results. Because of the rapid accumulation of information about the diagnosis and treatment of these tumors, the National Comprehensive Cancer Network convened a GIST task force to provide updated recommendations in 2010. As understanding of these tumors advances, rapid changes in recommendations will continue and should warrant regular updates in tumor management.
Author List
Grignol VP, Termuhlen PMMESH terms used to index this publication - Major topics in bold
Antineoplastic AgentsChemotherapy, Adjuvant
Gastrectomy
Gastrointestinal Stromal Tumors
Humans
Morbidity
Survival Rate
United States
