Exciting new murine model of cGVHD. Blood 2012 Feb 09;119(6):1331-2
Date
02/11/2012Pubmed ID
22323409DOI
10.1182/blood-2011-12-393496Scopus ID
2-s2.0-84856832037 (requires institutional sign-in at Scopus site) 1 CitationAbstract
In this issue of Blood, Srinivasan et al report that mice conditioned for allogeneic hematopoietic stem cell transplantation with cyclophosphamide and total body irradiation develop wide-spectrum manifestations of chronic graft-versus-host disease (cGVHD).1 This represents an exciting new preclinical model that can be used to uncover mechanisms of cGVHD and test interventional therapies.









