Successful treatment of radiation nephropathy with angiotensin II blockade. Int J Radiat Oncol Biol Phys 2003 Jan 01;55(1):190-3
Date
12/31/2002Pubmed ID
12504053DOI
10.1016/s0360-3016(02)03793-8Scopus ID
2-s2.0-0037216452 (requires institutional sign-in at Scopus site) 45 CitationsAbstract
PURPOSE: The aim of this report is to document the successful treatment of radiation nephropathy.
METHODS: Clinical case report with statistical analysis of evolution of kidney function.
RESULTS: A case of radiation nephropathy was found in a kidney transplant recipient whose kidney transplant had been irradiated with 750 cGy 23 years previously. Use of the angiotensin II blocker, losartan, was associated with significant stabilization of the kidney function.
CONCLUSION: Radiation nephropathy can be successfully treated. Other normal-tissue radiation injuries may also be treatable.
Author List
Cohen EP, Hussain S, Moulder JEMESH terms used to index this publication - Major topics in bold
AdultAngiotensin II
Female
Glomerular Filtration Rate
Humans
Kidney
Kidney Transplantation
Radiotherapy
