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TAFI made stickier. Blood 2012 Apr 12;119(15):3380-1

Date

04/14/2012

Pubmed ID

22500053

DOI

10.1182/blood-2012-02-406652

Scopus ID

2-s2.0-84859856443 (requires institutional sign-in at Scopus site)   1 Citation

Abstract

Bleeding in hemophilia is the result of factor VIII/IX deficiency with corresponding reduced thrombin production and enhanced fibrinolysis secondary to lower thrombin activatable fibrinolysis inhibitor (TAFI) production. Factor replacement is the cornerstone of hemophilia treatment but is often not possible in developing countries.

Author List

Abshire T

Author

Thomas Abshire MD Emeritus Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Blood Coagulation
Dog Diseases
Hemophilia A
Humans
Receptors, Thrombin
Recombinant Proteins