The diagnosis and management of empyema in children: a comprehensive review from the APSA Outcomes and Clinical Trials Committee. J Pediatr Surg 2012 Nov;47(11):2101-10
Date
11/21/2012Pubmed ID
23164006DOI
10.1016/j.jpedsurg.2012.07.047Scopus ID
2-s2.0-84869469392 (requires institutional sign-in at Scopus site) 179 CitationsAbstract
The aim of this study is to review the current evidence on the diagnosis and management of empyema. The American Pediatric Surgical Association Outcomes and Clinical Trials Committee compiled 8 questions to address. A comprehensive review was performed on each topic. Topics included the distinction between parapneumonic effusion and empyema, the optimal imaging modality in evaluating pleural space disease, when and how pleural fluid should be managed, the first treatment option and optimal timing in the management of empyema, the optimal chemical debridement agent for empyema, therapeutic options if chemical debridement fails, therapy for parenchymal abscess or necrotizing pneumonia and duration of antibiotic therapy after an intervention. The evidence was graded for each topic to provide grade of recommendation where appropriate.
Author List
Islam S, Calkins CM, Goldin AB, Chen C, Downard CD, Huang EY, Cassidy L, Saito J, Blakely ML, Rangel SJ, Arca MJ, Abdullah F, St Peter SD, APSA Outcomes and Clinical Trials Committee, 2011-2012Authors
Casey Matthew Calkins MD Professor in the Surgery department at Medical College of WisconsinLaura Cassidy PhD Associate Dean, Institute Director, Professor in the Institute for Health and Humanity department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Anti-Bacterial AgentsChild
Combined Modality Therapy
Debridement
Deoxyribonucleases
Drainage
Empyema, Pleural
Expectorants
Fibrinolytic Agents
Humans
Pleural Cavity
Pneumonia, Bacterial
Thoracic Surgery, Video-Assisted
Tomography, X-Ray Computed
Ultrasonography
