Medical College of Wisconsin
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Effects of anesthetics, sedatives, and opioids on ventilatory control. Compr Physiol 2012 Oct;2(4):2281-367

Date

05/31/2013

Pubmed ID

23720250

DOI

10.1002/cphy.c100061

Scopus ID

2-s2.0-84891708026 (requires institutional sign-in at Scopus site)   28 Citations

Abstract

This article provides a comprehensive, up to date summary of the effects of volatile, gaseous, and intravenous anesthetics and opioid agonists on ventilatory control. Emphasis is placed on data from human studies. Further mechanistic insights are provided by in vivo and in vitro data from other mammalian species. The focus is on the effects of clinically relevant agonist concentrations and studies using pharmacological, that is, supraclinical agonist concentrations are de-emphasized or excluded.

Author List

Stuth EA, Stucke AG, Zuperku EJ

Authors

Astrid G. Stucke MD Professor in the Anesthesiology department at Medical College of Wisconsin
Eckehard A. Stuth MD Professor in the Anesthesiology department at Medical College of Wisconsin
Edward J. Zuperku PhD, MS Emeritus Professor in the Anesthesiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Analgesics, Opioid
Anesthetics, General
Animals
Carotid Body
Chemoreceptor Cells
Dose-Response Relationship, Drug
Humans
Hypnotics and Sedatives
Ion Channels
Models, Animal
Motor Neurons
Respiratory Center
Respiratory Mechanics
Synaptic Transmission