[Contribution of the endogenous opioid system to regulation of heart resistance to the arrhythmogenic effect of short-term ischemia and reperfusio]. Izv Akad Nauk Ser Biol 2005(4):453-9
Date
10/11/2005Pubmed ID
16212267Scopus ID
2-s2.0-27744528108 (requires institutional sign-in at Scopus site)Abstract
Preliminary selective blockade of micro, delta1, delta2, kappa1, and kappa2 opioid receptors proved to have no effect on the incidence of ventricular arrhythmias during a 10-min coronary occlusion and subsequent reperfusion in ketamine-anesthetized rats. We propose that the endogenous opioid system has no considerable role in regulation of heart resistance to the arrhythmogenic effect of short-term local ischemia and subsequent reperfusion.
Author List
Maslov LN, Liishmanov AIu, Budankova EV, Stakheev DL, Solenkova NV, Barzakh EI, Oeltgen PR, Gross GJ, Chang WSMESH terms used to index this publication - Major topics in bold
AnimalsHeart Diseases
Myocardium
Narcotic Antagonists
Opioid Peptides
Rats
Rats, Wistar
Receptors, Opioid
