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AKR T-cell acute lymphoblastic leukemia: a model for human T-cell leukemia. Biomedicine 1977 Oct;26(5):309-11

Date

10/01/1977

Pubmed ID

303119

Scopus ID

2-s2.0-0017661736 (requires institutional sign-in at Scopus site)   15 Citations

Abstract

In humans, the T cell form of acute lymphoblastic leukemia has proved to be a difficult therapeutic challenge; long-term remissions are unusual. Spontaneous T cell leukemia of AKR mice bears many similarities to the human disease and is proposed as an experimental model in which to test treatment strategies prior to clinical trial.

Author List

Bortin-M, Truitt RL

Author

Robert L. Truitt PhD Emeritus Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Acute Disease
Animals
Disease Models, Animal
Humans
Leukemia, Lymphoid
Mice
Mice, Inbred AKR
Rodent Diseases
T-Lymphocytes