Multi-center genetic study of hypertension: The Family Blood Pressure Program (FBPP). Hypertension 2002 Jan;39(1):3-9
Date
01/19/2002Pubmed ID
11799070DOI
10.1161/hy1201.100415Scopus ID
2-s2.0-18244379376 (requires institutional sign-in at Scopus site) 173 CitationsAbstract
The Family Blood Pressure Program (FBPP) consists of 4 independently established multicenter networks of investigators who have complementary approaches to the genetics of blood pressure levels and hypertension. The program has recruited participants from the African American, Mexican American, Asian, and non-Hispanic white populations. Each network utilized study designs, laboratory measurements, and analytic methods that made efficient use of the unique characteristics of their populations and the investigators' expertise. The individual networks subsequently unified core study components into a single cohesive program. The unified FBPP includes (1) standardized clinic and laboratory protocols for core variables to facilitate direct comparison of results among networks, (2) coordination among laboratories to avoid unnecessary duplication of effort, (3) utilization of a single laboratory for genome-wide marker typing, and (4) a pooled data set containing phenotype and genotype information from >11 000 individuals.
Author List
FBPP InvestigatorsMESH terms used to index this publication - Major topics in bold
Blood PressureEpidemiologic Methods
Family Health
Genetic Linkage
Genetic Predisposition to Disease
Humans
Hypertension
