Faculty Collaboration Database

Recent Visitors

Matthew Myrvik PhD

Joseph S. Goveas MD

Beth A. Erickson MD

Carolyn A. Taylor PhD

Scott P. Levick PhD

CURRICULUM VITAE

Meghen B. Browning MD

Assistant Professor
Department of Pediatrics
Division of Hematology/Oncology

OFFICE ADDRESS:

MACC Fund Research Center

8701 Watertown Plank Rd

Milwaukee, WI 53226

Phone: 414-955-4628

Fax: 414-456-6543

CITIZENSHIP: United States

EDUCATION:

1986 - 1990 BA, Macalester College, St. Paul, MN

1990 - 1995 MD, University of Missouri-Columbia School of Medicine (cum laude), Columbia, MO

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:

1995 - 1998 Residency, Pediatrics, Medical College of Wisconsin, Milwaukee, WI

2000 - 2003 Fellowship, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI

2003 - 2004 Research Fellowship, Pediatrics, Bone Marrow Transplant, Medical College of Wisconsin, Milwaukee, WI

FACULTY APPOINTMENTS:

2004 - Present Assistant Professor, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI

ADMINISTRATIVE APPOINTMENTS:

1998 - 2000 Medical Officer, Public Health Service, Navajo Nation, Chinle, AZ

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:

2007 - Present Director, Pediatrics, Musculoskeletal Oncology Program, Children's Hospital of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:

2000 - Present Staff Physician, Pediatrics, Hematology/Oncology/BMT, Children's Hospital of Wisconsin, Milwaukee, WI

SPECIALTY BOARDS AND CERTIFICATION:

Board Certified	Issue Date	Expiration
American Board of Pediatrics	10/1999	None
American Board of Pediatrics, Hematology-Oncology	10/2004	None

Licensure	Number	Issue Date	Expiration
Medical License	37958-20	7/1996	None

AWARDS AND HONORS:

3/1998 First place, Resident Research Day

2003 - 2004 One of 20 fellows and junior faculty from across the US and Canada selected on a competitive basis for participation in the first year of this training and mentoring program, American Society of Hematology’s Clinical Research Training Institute (ASH- CRTI)

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:

American Academy of Pediatrics (Member)

Children's Oncology Group (Member)

American Society of Hematology (Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:

Journal Review

Journal of Pediatric Hematology/Oncology

Ophthalmic Plastic & Reconstructive Surgery

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:

Co-Chair, Logistics Committee, Children's Oncology Group (COG)

Member, Neuroblastoma Committee: High-risk Protocol Consolidation Task Force, Children's Oncology Group (COG)

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:

Active
Peer Review
Title:	Preclinical Study to Optimize Anti-tumor Immune Activation Against Breast Cancer and Multiple Myeloma Using Tumor Vaccination in Combination with Lymphodepletion and Immune Modulating Agents
Source:	Clinical and Translational Science Institute (CTSI)
Role:	Co-Investigator
PI:	Jill Gershan
Dates:	2011 - 2013
Direct Funds:	$50,000

Title:	Cellular and Adoptive Immunotherapy using Hematopoietic Cell Transplantation and NK Cell Infusion for the Treatment of High-Risk Pediatric and Adult Solid Tumors: a Phase I/II Study
Source:	Clinical and Translational Science Institute (CTSI)
Role:	Co-Investigator
PI:	Monica Thakar/Subramaniam Malarkannan
Dates:	7/1/2012 - 6/30/2013
Direct Funds:	$50,000

Title:	Use of a Power Hickman for Peripheral Blood Stem Cell Collection in Pediatric Patients
Source:	Unfunded; data submitted to QHS team and is in the process of being reviewed
Role:	Co-Investigator, Sr. Investigator
PI:	Mollie Haddigan-Mulberry

Title:	MTP-OS-403 - actively enrolling patients to study the compassionate use study allowing the use of liposomal Muramyl Tripeptide Phosphatidyl Ethanolamine for recurrent osteosarcoma patients
Source:	Millennium Pharmaceuticals
Role:	Local PI

Title:	Pain Study - goal of this study is to develop a data-based recommendation for initiation of pain control in the post-operative period for bone tumor patients
Source:	Unfunded; recently IRB approved, feasibility analysis pending
Role:	Co-Principal Investigator
PI:	David King/Meg Browning

Pending
Peer Review
Title:	Gender Study - goal of this study is to link tumor necrosis to gender-based outcome inequality in patients with primary bone tumors
Source:	Unfunded; data collection in progress
Role:	Co-Principle Investigator
PI:	David King/Meg Browning

Prior
Peer Review
Title:	Ruth L. Kirschstein National Research Service Award (NRSA)
Source:	NIH
Dates:	6/28/2003 - 6/27/2005

Title:	Vaccine Responses and the Effect of Chemotherapy
Source:	MACC Fund Research Grant
Role:	PI
Dates:	7/1/2008 - 6/30/2009
Direct Funds:	$40,000

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:

Local

1. Invited Speaker, The Laboratory and Bone Marrow Transplants, Milwaukee Society for Clinical Laboratory Science, Milwaukee, WI, 10/2003

Regional

1. Invited Speaker, Pediatric Bone Tumors, Northwestern Lake Forest Hospital, Grayslake, IL, 7/2008

PEER REVIEWED WORKSHOPS/PRESENTATIONS:

National

1. Browning MB, Baylerian DM, Johnson ST, Gottschall, JL, Positive direct antiglobulin tests in a pediatric population, American Society of Hematology (ASH) 44th Annual Meeting - Poster Presentation, Orlando, FL, 12/2001

2. Browning MB, Kugathasan S, Casper JT, Margolis DA, Infliximab for chronic GVHD in pediatric patients, American Society of Hematology (ASH) 45th Annual Meeting - Poster Presentation, Philadelphia, PA, 12/2002

3. Browning MB, Woodliff JE, Konkol MC, Pati NT, Ghosh S, Truitt RL, Johnson BD, The T cell activation marker CD150 can be used to identify alloantigen-activated CD4(+)25+ regulatory T cells, Tandem Bone Marrow Transplant Meeting - Poster Presentation, Keystone, CO, 1/2003

4. Keever-Taylor CA, Browning MB, Johnson BD, Behn B, Truitt, RL, Optimization of culture methods for the expansion of CD4+CD25+ regulatory t cells for potential clinical use, Tandem Bone Marrow Transplant Meeting (Combined ASBMT and IBMTR/ABMTR Annual Meetings) - Poster Presentation, New Orleans, LA, 1/2005

COMMITTEE SERVICE:

Hospital

2003 - Present Interviewer, Intern Selection Committee, Children's Hospital of Wisconsin

2008 - Present Subcommittee Member, COG Neuroblastoma Group, Children's Oncology Group

2008 Chair, Inpatient Planning Committee, Pediatrics, Children's Hospital of Wisconsin

2011 Co-Leader, Collaborative Practice Guidelines Committee, Children's Hospital of Wisconsin

MEDICAL COLLEGE TEACHING ACTIVITIES:

Medical Student Education

2010 - Present Clinical Mentor for M-1 Students

Facilitator for Professionalism Course

Resident and Fellow Education

3/1998 Resident Research Day Presentation - Age-Related Changes in the Human T cell Receptor Repertoire

2000 - Present Ward attending/teacher for Oncology fellows and residents 8 weeks/year (average)

2003 - 2005 Facilitator for Biochemistry Clinical Correlation Sessions

2004 - 2011 3 lectures/month (average) for Oncology Residents

2006 - Present Clinic Supervisor for Oncology Fellow

2007 - Present 2 lectures/year (average) for Oncology Fellows

Supervise fellow for periodic Tumor Board presentations

Continuing Medical Education

9/2005 Grand Rounds Presentation - Leukemia and Lymphoma

8/2008 Organized speaker visit for Musculoskeletal Oncology program; included clinic visits, Grand Rounds, Children’s Research Institute talk

Postdoctoral Fellow Education

2005 - 2007 Clinical Mentor for Medical Scientist Training Program MD-PhD student

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:

Medical Students

Medical College of Wisconsin, 2005 - 2007 Clinical Mentor for Medical Scientist Training Program

Clinical/Research Fellows

Medical College of Wisconsin, 2006 - Present Oncology Clinic Supervisor

CAREER DEVELOPMENT:

2011 Initiated Performance Improvement Module, “Safe Prescription and Medication Order Writing” through the ABP as component of maintenance of certification

2011 Participated in day-long workshop presented by Rank and Tenure committee to better prepare for career advancement.

BIBLIOGRAPHY

Refereed Journal Publications/Original Papers

1. Browning MB, Camitta BM. The surgeon's role in pediatric orbital malignancies: an oncologist's perspective. Ophthal Plast Reconstr Surg. 2003 Sep;19(5):340-4.

2. Browning MB, Woodliff JE, Konkol MC, Pati NT, Ghosh S, Truitt RL, Johnson BD. The T cell activation marker CD150 can be used to identify alloantigen-activated CD4(+)25+ regulatory T cells. Cell Immunol. 2004 Feb;227(2):129-39.

3. Keever-Taylor CA, Browning MB, Johnson BD, Truitt RL, Bredeson CN, Behn B, Tsao A. Rapamycin enriches for CD4(+) CD25(+) CD27(+) Foxp3(+) regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients with multiple sclerosis. Cytotherapy. 2007;9(2):144-57.

4. Browning MB, Woodliff JE, Konkol MC, Pati NT, Ghosh S, Truitt RL, Johnson BD. The T cell activation marker CD150 can be used to identify alloantigen-activated CD4(+)25+ regulatory T cells. Cell Immunol. 2004 Feb;227(2):129-39.

5. Maronn M, Catrine K, North P, Browning MB, Kerschner JE, Noel R, Drolet BA, Kelly M. Expanding the phenotype of multifocal lymphangioendotheliomatosis with thrombocytopenia. Pediatr Blood Cancer. 2009 Apr;52(4):531-4.

Abstracts

1. Browning MB, Baylerian DM, Johnson ST, Gottschall, JL. Positive direct antiglobulin tests in a pediatric population. Blood (American Society of Hematology Meeting Abstracts). 2001 Nov 16;98(11 Pt 1):1a-953a.

2. Browning MB, Kugathasan S, Casper JT, Margolis DA. Infliximab for chronic GVHD in pediatric patients. Blood (American Society of Hematology Meeting Abstracts). 2001 Nov 16;98(11 Pt 1):1a-953a.

3. Browning MB, Woodliff JE, Konkol MC, Pati NT, Ghosh S, Truitt RL, Johnson BD. The T cell activation marker CD150 can be used to identify alloantigen-activated CD4(+)25+ regulatory T cells. Biol Blood Marrow Tr. 2003 Feb;09(suppl).

4. Keever-Taylor CA, Browning MB, Johnson BD, Behn B, Truitt RL. Optimization of culture methods for the expansion of CD4+CD25+ regulatory T cells for potential clinical use. Biol Blood Marrow Tr. 2005 Feb; 11(2) Suppl 1:44.