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CURRICULUM VITAE

Monica Thakar MD
Assistant Professor
Department of Pediatrics
Division of Hematology/Oncology

OFFICE ADDRESS:
MACC Fund Research Center
8701 Watertown Plank Rd
Milwaukee, WI 53226

CITIZENSHIP:  USA

EDUCATION:
1993 - 1997 BS - Biology, University of South Carolina, Columbia, SC
1997 - 2001 MD, Medical University of South Carolina, Charleston, SC

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
2001 - 2004 Intern and Resident, Pediatrics, University of Chicago, Chicago, IL
2004 - 2007 Fellow, Pediatrics, Hematology-Oncology, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA
2007 - 2008 Senior Fellow, Pediatrics, Hematology-Oncology, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA

FACULTY APPOINTMENTS:
2008 - 2009 Research Associate, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
2008 - 2009 Acting Instructor , Pediatrics, University of Washington, Seattle, WA
2010 - Present Affiliate Member, Fred Hutchinson Cancer Research Center, Seattle, WA
2010 - Present Assistant Professor, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
2007 - 2009 Medical Staff, Seattle Children's Hospital, Seattle, WA
2008 - 2009 Medical Staff, University of Washington, Seattle, WA
2008 - 2009 Medical Staff, Seattle Cancer Care Alliance, Seattle, WA
2010 - Present Medical Staff, Children's Hospital of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
2007 - 2009 Medical Staff, Seattle Children’s Hospital, Seattle, WA
2008 - 2009 Medical Staff, University of Washington Medical Center, Seattle, WA
2008 - 2009 Medical Staff, Seattle Cancer Care Alliance, Seattle, WA
2010 - Present Medical Staff, Pediatrics, Hematology/Oncology/BMT, Children’s Hospital of Wisconsin, Milwaukee, WI

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
General Pediatrics
2006
2015
Pediatric Hematology-Oncology
2013
2023
 
Licensure
Number Issue DateExpiration
Medical License
2004
2013
Federal DEA License
2004
2015
Medical License
2010
2015
 
AWARDS AND HONORS:
1993 - 1997 Dean’s List, South Carolina Honors College, University of South Carolina
1993 - 1997 Valedictorian Full-Tuition Scholarship, University of South Carolina
1995 Howard Hughes Undergraduate Research Award in Ecology, University of South Carolina
1997 SC Experimental Program to Stimulate Competitive Research (SC EPSCoR) Grant in Developmental Biology, University of South Carolina
2006 Loan Repayment Award, NIH
2007 Travel Award, American Society of Hematology Annual Meeting
2007 Travel Award, Fanconi Anemia Research Fund Annual Meeting
2007 Fellows’ Research Day Award, Seattle Children’s Hospital
2008 Clinical Research Training Institute Workshop Attendance (declined), American Society of Hematology
2008 Cancer Research Clinical Training Workshop Attendance, American Society of Clinical Oncology/American Association of Cancer Research
2008 Travel Award, Fanconi Anemia Research Fund Annual Meeting
2008 Clinical Training Course Attendance (declined), American Society for Blood and Marrow Transplantation (ASBMT)
2011 - 2012 Clinical Research Scholars Program, Clinical and Translational Research Institute (CTSI)
2011 Travel Award, Fanconi Anemia Research Fund Annual Meeting
2012 - Present Young Investigator Travel Award - 2nd International Workshop on the Biology, Prevention, and Treatment of Relapse After Hematopoietic Stem Cell Transplantation Meeting, NIH
2013 Pediatric Faculty Teacher of the Year (as chosen by Pediatric House Staff), Children's Hospital of Wisconsin
2013 Health Volunteers Overseas Program Volunteer Teaching BMT in Underserved Populations, American Society of Hematology
2013 Travel Award, ASBMT/CIBMTR Tandem Meeting

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2005 - Present American Society of Hematology (ASH) (Member)
2006 - 2009 American Society of Clinical Oncology (ASCO) (Associate Member)
2006 - Present American Society for Blood and Marrow Transplantation (ASBMT) (Member)
2007 - 2009 American Association for the Advancement of Science (AAAS) (Sponsored Member)
2008 - Present American Society of Pediatric Hematology-Oncology (ASPHO) (Member)
2008 - Present Pediatric Blood and Marrow Transplant Consortium (PBMTC) (Member)
2008 - Present Children’s Oncology Group (COG) (Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
2010 - Present Journal of Pediatric Hematology and Oncology
2011 - Present Pediatric Blood and Cancer
2011 - Present Biology of Blood and Marrow Transplantation
2012 - Present Annals of Hematology

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2008 - 2009 Protocol Reviewer, Clinical Investigator’s Meeting, Fred Hutchinson Cancer Research Center, Seattle, WA
2008 - 2009 Head, Transplantation Biology/Marrow Failure Monthly Clinical Research Meeting, Fred Hutchinson Cancer Research Center, Seattle, WA
2010 - Present Member, Bone Marrow Transplant QI Program Committee, Medical College of Wisconsin
2010 - Present Member, Scholarship Oversight Committee for Sam Milanovich, MD, Medical College of Wisconsin, Pediatric Hematology/Oncology Fellowship Program
2011 - 2013 Advisor and Mentor, Medical School Discovery Curriculum for Haley Robinson, Medical College of Wisconsin

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2010 Co-Chair, Session on Pediatric Alternative Donor Transplantation, American Society of Hematology Annual Meeting, Orlando, FL
2010 Member, Abstract Review Committee for Alternative Donor Transplantation, American Society of Hematology Annual Meeting

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Donor lymphocyte infusions using natural killer cells after transplant
Source:
Midwest Athletes Against Childhood Cancer (MACC) Fund – New faculty recruit start-up funds
Role:
Principal Investigator
PI:
Thakar M
Dates:
1/1/2010 - 12/31/2012
Direct Funds:
$60,000
 
Title:
Hematopoietic Cell Transplantation for Treatment of Patients with Primary Immunodeficiencies and other Nonmalignant Inherited Disorders using low-dose Total Body Irradiation (TBI) and Fludarabine (FLU) with or without Campath
Source:
Fred Hutchinson Cancer Research Center
Role:
Local Principal Investigator
PI:
Thakar, Monica MD; Burroughs, Lauri, Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Dates:
4/21/2010 - Present
 
Title:
FHCRC Protocol 2064: Nonmyeloablative Hematopoietic Cell Transplantation for Patients with Fanconi Anemia Using Alternative Marrow Donors: A Phase I/II Dose-Finding Study
Source:
Fred Hutchinson Cancer Research Center - Multi-Institutional Clinical Trials. IRB approval at MCW on 11/16/10.
Role:
Local Principal Investigator
PI:
Kiem HP (FHCRC)
Dates:
4/21/2010 - Present
 
Title:
BMT CTN 0801: A Phase II/III Randomized, Multi-center Trial Comparing Sirolimus plus Prednisone, Sirolimus/ECP plus Prednisone, and Sirolimus/Calcineurin Inhibitor plus Prednisone for the treatment of Chronic Graft-versus-Host-Disease
Source:
National Marrow Donor Program (NMDP) - Multi-institutional trial. IRB approval at the Medical College of Wisconsin 1/25/11.
Role:
Local Principal Inestigator
PI:
Thakar, Monica MD, Carpenter, Paul, MB, BS (Fred Hutchinson Cancer Research Center) & Arora, Mukta, MD (University of Minnesota - Clinical and Translational Science Institute)
Dates:
1/25/2011 - Present
 
Title:
Support for Protocol 2230, Miltenyi CliniMACS Disposable Agents
Source:
Miltenyi Corporation
Role:
IND Sponsor/Holder BB IND 13794
Dates:
3/24/2011 - 3/24/2016
Direct Funds:
$294,500 (supplies)
 
Title:
A Phase I/II trial evaluating NK cell immunotherapy in relapsed and refractory pediatric solid tumors
Source:
Pablove Foundation
Role:
Principal Investigator
Dates:
7/1/2012 - 6/30/2013
Direct Funds:
$50,000
 
Title:
Cellular and adoptive immunotherapy using hematopoietic cell transplantation and NK cell infusion for the treatment of high-risk pediatric and adult solid tumors: a Phase I/II Study
Source:
Clinical and Translational Science Institute (Thakar/Malarkannan)
Role:
Principal Investigator of new clinical trial
Dates:
7/1/2012 - 6/30/2013
Direct Funds:
$50,000
 
Title:
NK cell immunotherapy in relapsed and refractory solid tumors
Source:
American Cancer Society Pilot Research Grant (Thakar/Malarkannan)
Role:
Principal Investigator of new clinical trial
Dates:
7/1/2012 - 6/30/2013
Direct Funds:
$30,000
 
Title:
Acquisition of graft-versus-host disease (GVHD) samples for pre-clinical studies
Source:
Investigator-initiated, prospective and retrospective tissue acquisition for studying immunohistochemistry. IRB approval at Froedert Hospital
Role:
Joint collaboration with S. Malarkannan, J. Palmer, and P. Hari
 
Non-Peer Review
Title:
FHCRC Protocol 2230: A Phase II Study Evaluating the Safety and Efficacy of Adding a Single Prophylactic Donor Lymphocyte Infusion (DLI) of Natural Killer Cells Early After Nonmyeloablative, HLA-Haploidentical Hematopoietic Cell Transplantation
Source:
Fred Hutchinson Cancer Research Center - Multi-Institutional Clinical Trials. IRB approval at MCW on 5/5/10.
Role:
Local Principal Investigator
PI:
Sandmaier B (FHCRC)
Dates:
5/5/2010 - Present
 
Title:
BMT CTN 0801: A Phase II/III Randomized, Multi-center Trial Comparing Sirolimus plus Prednisone, Sirolimus/ECP plus Prednisone, and Sirolimus/Calcineurin Inhibitor plus Prednisone for the treatment of Chronic Graft-versus-Host-Disease
Source:
Bone Marrow Transplant Clinical Trials Network (BMT CTN)
Role:
Local Principal Investigator
PI:
CO-PIs: Carpenter P and Arora M
Dates:
1/25/2011 - Present
 
Pending
Peer Review
Title:
Laboratory application of natural killer cells for adoptive immunotherapy
Source:
Midwest Athletes Against Childhood Cancer (MACC) Fund – Novel Initiative Request
Dates:
12/2010 - Present
Direct Funds:
$55,000
 
Title:
Manufacturing NK cells for treatment of post-transplant relapse and GVHD
Source:
Doris Duke Clinical Scientist Development Award
Direct Funds:
$450,000
 
Prior
Peer Review
Title:
Pediatric Oncology Translational Research Program
Source:
NIH/NCI T32 CA09351
Role:
Pediatric Hematology-Oncology Fellow
PI:
Bernstein I
Dates:
7/1/2005 - 6/30/2007
 
Title:
Stem Cell Transplantation: Basic/Clinical Research Sub-Project 1:Allogeneic hematopoietic cell transplantation for nonmalignant diseases
Source:
NIH/NHLBI HL 36444-28
Role:
Investigator – 20% effort
PI:
Storb R
Dates:
8/1/2007 - 11/30/2009
Direct Funds:
$94,645 (direct costs per year)
 
Title:
Nonmyeloablative Hematopoietic Cell Transplantation for Patients with Fanconi Anemia Using Alternative Marrow Donors: A Phase I/II Dose-Finding Study
Source:
Fanconi Anemia Research Foundation
Role:
Principal Investigator of Protocol 2064 – 40% effort
PI:
Thakar M
Dates:
1/1/2008 - 12/31/2009
Direct Funds:
$81,786
 
Title:
Pilot Project to Support Product Characterization and Immune Reconstitution Studies
Source:
Orin Edson Foundation
Role:
Co-Principal investigator– 10% effort
PI:
Thakar M & Sandmaier B
Dates:
7/1/2008 - 12/31/2009
Direct Funds:
$24,886
 
Title:
Mixed Hematopoietic Chimerism after Stem Cell Allografts: Sub project 3: Mixed Chimerism in the Treatment of Leukemias
Source:
NIH/NCI CA078902-11
Role:
Investigator – 10% effort
PI:
Storb R
Dates:
8/1/2008 - 1/31/2009
Direct Funds:
$118,102
 
Title:
FHCRC Protocol 2230: A Phase II Study Evaluating the Safety and Efficacy of Adding a Single Prophylactic Donor Lymphocyte Infusion (DLI) of Natural Killer Cells Early After Nonmyeloablative, HLA-Haploidentical HCT
Source:
Fred Hutchins Cancer Reserach Center
Role:
Principal Investigator
Dates:
2008 - 2009
 
Title:
FHCRC Protocol 2064: Nonmyeloablative Hematopoietic Cell Transplantation for Patients with Fanconi Anemia Using Alternative Marrow Donors: A Phase I/II Dose-Finding Study
Source:
Fred Hutchins Cancer Research Center
Role:
Principal Investigator
Dates:
2008 - 2009
 
Title:
Stem Cell Transplantation: Basic/Clinical Research Sub-project 2: Nonmyeloblative allografts in DLA-haploidentical dogs: engraftment and GVHD
Source:
NIH/NHLBI HL 36444
Role:
Investigator – 10% effort
PI:
Sandmaier B & Storb R
Dates:
2/1/2009 - 11/30/2009
Direct Funds:
$231,695 (direct costs per year)
 
Title:
A Phase I/II Study Evaluating the Safety and Efficacy of Adding a Single Prophylactic Donor Lymphocyte Infusion of Natural Killer Cells Early After Nonmyeloablative
Source:
Kuni Foundation
Role:
Co-Principal Investigator of Protocol 2230
Dates:
4/1/2010 - 3/30/2011
Direct Funds:
$124,843
 
Title:
Adoptive immunotherapy using natural killer cells
Source:
Rebecca Jean Slye Endowment
Role:
Principal Investigator of new laboratory project
PI:
Thakar M
Dates:
1/1/2011 - 12/31/2011
Direct Funds:
$15,000
 
Title:
A Phase I/II Study Evaluating the Safety and Efficacy of Adding a Single Prophylactic Donor Lymphocyte Infusion of Natural Killer Cells Early After Nonmyeloablative, HLA-Haploidentical Hematopoietic Cell Transplantation
Source:
Hyundai Scholars Program
Role:
Co-Principal Investigator of Protocol 2230
Dates:
2/1/2011 - 12/31/2012
Direct Funds:
$50,000
 
INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
National
1. HLA-haploidentical hematopoietic cell transplantation for Fanconi Anemia, Collaborator/Multi-Institutional Annual Mixed Chimerism Meeting, Seattle, WA, 5/2007
2. Pre-emptive donor natural killer cell donor lymphocyte infusion early after nonmyeloablative, HLA-haploidentical hematopoietic cell transplantation, Collaborator/Multi-Institutional Annual Mixed Chimerism Meeting, Seattle, WA, 5/2008
3. CD3-Depleted donor lymphocyte infusions after canine MHC-haploidentical nonmyeloablative hematopoietic cell transplantation, Collaborator/Multi-Institutional Annual Mixed Chimerism Meeting, Seattle, WA, 5/2008
4. Workshop for Transplantation of Bone Marrow Failure and Acute Myeloid Leukemia in Fanconi Anemia, Invited Participant, 20th Annual Fanconi Anemia Research Fund Annual Symposium, Eugene, OR, 10/2008
5. Endocrinopathy in Fanconi Anemia, 1st Annual Brazil Fanconi Anemia Family Meeting and Educational Symposium, Curitiba, Brazil, 11/2009
6. Severe aplastic anemia, Data Managers Conference, American Society of Blood and Marrow Transplantation Annual Meeting, Orlando, FL, 1/2010
7. Update on Protocol 2230, Collaborator/Multi-Institutional Annual Mixed Chimerism Meeting, Seattle, WA, 5/2010
8. Update on Protocol 2230, Collaborator/Multi-Institutional Annual Mixed Chimerism Meeting, Seattle, WA, 5/2011 - 5/2010
 
PEER REVIEWED WORKSHOPS/PRESENTATIONS:
National
1. Thakar MS, Liedel JL, Rubin CM, Brown M, Bacha EA, Kahana MD, FVIIa for Peri-Operative Bleeding in the PICU and NICU, Pediatric Academic Society Meeting, San Francisco, CA, 5/2004
2. Thakar MS, Gooley TA, Santos EB, Storb RF, Sandmaier BM, High-dose methotrexate as part of a novel immunosuppressive regimen in canine MHC-haploidentical hematopoietic cell transplantation, American Society of Hematology Annual Meeting - Poster Presentation, Orlando, FL, 12/2006
3. Thakar MS, Woolfrey AE, Kletzel M, Frangoul H, Pulsipher M, Sandmaier B, Storb, Flowers M, Kurre P, Kiem HP, HLA-matched unrelated donor stem cell transplantation using low-dose total body irradiation and fludarabine for Fanconi Anemia patients with aplastic anemia, Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium - Poster Presentation, Chicago, IL, 10/2007
4. Thakar MS, Storer B, Chauncey T, MD, Pulsipher M, Maloney D, Storb R, Sandmaier B, Reversal of low chimerism following non-myeloablative hematopoietic cell transplantation using pentostatin and donor lymphocyte infusions, American Society of Hematology Annual Meeting, Atlanta, GA, 12/2007
5. Thakar MS, Storer B, Storb R, Shizuru J. Niederwieser D, Pulsipher M, Sahebi F, Sorror M, Chen Y, Georges G, Maloney D, Woolfrey A, Sandmaier BM, Treatment of pediatric high-risk malignancies using non-myeloablative (NM) hematopoietic cell transplantation (HCT): a multi-institutional experience, American Society of Blood and Marrow Transplantation Tandem Meetings, Orlando, FL, 2/2010
 
International
1. Wilbur DS, Hamilin DK, Chyan MK, Thakar MS, Pantelias AA, Santos EB, Pagel JM, Press OW, Sandmaier BM, 211At-Labeling Using Dianionic Decaborate Cage Moieties Provides High Labeling Efficiency and High In Vivo Stability, Workshop on Alpha Emitting Radionucleotides in Therapy, Aachen, Germany, 4/2007
 
COMMITTEE SERVICE:
Medical College
2010 - Present Member, Scholarship Oversight Committee for Sam Milanovich, MD, Hematology/Oncology/BMT, Pediatrics, Medical College of Wisconsin
2010 - Present Member, Bone Marrow Transplant QI Program Committee, Medical College of Wisconsin
 
MEDICAL COLLEGE TEACHING ACTIVITIES:
Resident and Fellow Education
2010 - Present Pediatric Residency Core Curriculum Lecture Series, Pediatric Hematology/Oncology Rotation - Introduction to Bone Marrow Transplantation
2010 - Present Pediatric Residency Core Curriculum Lecture Series, Pediatric Hematology/Oncology Rotation - Immunodeficiencies
 
Continuing Medical Education
1/2010 Pediatric Hematology/Oncology/BMT Tumor Board - Non-Myeloablative Transplants
12/2010 Pediatric Hematology/Oncology/BMT Tumor Board - Role of transplantation for refractory Hodgkin Lymphoma
2/2011 Pediatric Surgery Basic Science Lecture Series - Non-myeloablative hematopoietic cell transplantation
5/2011 Pediatric Allergy/Immunology Grand Rounds - The role of transplantation for primary immune deficiencies
6/2011 Pediatric Hematology/Oncology/BMT Tumor Board - Adoptive immunotherapy in oncology and BMT
 
EXTRAMURAL TEACHING (e.g. at Marquette, UWM, etc.):
Continuing Medical Education
6/2007 Fred Hutchinson Cancer Research Center, Program in Transplantation Biology, Clinical Research Division Work-in-Progress Seminar - High-dose post-transplant methotrexate as part of a novel immunosuppressive regimen in canine MHC-haploidentical hematopoietic cell transplantation
6/2007 Seattle Children’s Hospital, Division of Pediatric Hematology/Oncology Research Seminar - Canine MHC-haploidentical hematopoietic cell transplantation
7/2008 Fred Hutchinson Cancer Research Center, Non-myeloblative Transplantation Research Staff Didactic Series Presentation - Major histocompatibility complex: the alphabet soup
7/2008 Fred Hutchinson Cancer Research Center, Non-myeloablative transplantation research staff didactic series - Major histocompatibility complex: the alphabet soup
10/2008 Fred Hutchinson Cancer Research Center, Program in Transplantation Biology, Clinical Research Division Work-in-Progress Seminar - Update of studies in canine MHC-haploidentical non-myeloablative hematopoietic cell transplantation
 

BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Fox CW, Martin JD, Thakar MS, Mousseau TA. Clutch Size Manipulations in Two Seed Beetles, Stator limbatus (horn) and S. beali Johnson: Consequences for Fitness. Oecologia. 1996 Oct;108(1):88-94
2. Fox CW, Thakar MS, Mousseau TA. Egg Size Plasticity in a Seed Beetle: An Adaptive Maternal Effect. The American Naturalist. 1997 Jan;149(1):149-163
3. Nakamae H, Wilbur DS, Hamlin DK, Thakar MS, Santos EB, Fisher DR, Kenoyer AL, Pagel JM, Press OW, Storb R, Sandmaier BM. Biodistributions, myelosuppression, and toxicities in mice treated with an anti-CD45 antibody labeled with the alpha-emitting radionuclides bismuth-213 or astatine-211. Cancer Res. 2009 Mar 15;69(6):2408-15,PMCID:PMC2657815
4. Thakar MS, Zhang XB, Beard BC, Sale GE, Santos EB, Peterson L, Kiem HP, Sandmaier BM. Transmission and expansion of HOXB4-induced leukemia in two immunosuppressed dogs: implications for a new canine leukemia model. Exp Hematol. 2009 Oct;37(10):1157-66,PMCID:PMC2748853
5. Wilbur DS, Thakar MS, Hamlin DK, Santos EB, Chyan MK, Nakamae H, Pagel JM, Press OW, Sandmaier BM. Reagents for astatination of biomolecules. 4. Comparison of maleimido-closo-decaborate(2-) and meta-[(211)At]astatobenzoate conjugates for labeling anti-CD45 antibodies with [(211)At]astatine. Bioconjug Chem. 2009 Oct 21;20(10):1983-91,PMCID:PMC2888658.
6. Thakar MS, Forman SJ. ASH evidence-based guidelines: is there a role for second allogeneic transplant after relapse? Hematology Am Soc Hematol Educ Program. 2009:414-8
7. Thakar MS, Santos EB, Fricker S, Bridger G, Storb R, Sandmaier BM. Plerixafor-moblized stem cells alone are capable of inducing early engraftment across the MHC-haploidentical canine barrier. Blood. 2010 Jan 28;115(4):916-7,PMCID:PMC2815512
8. Thakar MS, Santos EB, Gooley TA, Sale G, Storb R, Kiem HP, Sandmaier BM. Evaluation of posttransplant methotrexate to facilitate engraftment in the canine major histocompatibility complex-haploidentical nonmyeloablative transplant model. Transplantation. 2010 Jul 15;90(1):14-22,PMCID:PMC2921965
9. Thakar MS, Kurre P, Storb R, Kletzel M, Frangoul H, Pulsipher MA, Leisenring W, Flowers ME, Sandmaier BM, Woolfrey A, Kiem HP. Treatment of Fanconi anemia patients using fludarabine and low-dose TBI, followed by unrelated donor hematopoietic cell transplantation. Bone Marrow Transplant. 2011 Apr;46(4):539-44,PMCID:PMC2976796
10. Rajasekaran K, Chu H, Kumar P, Xiao Y, Tinguely M, Samarakoon A, Kim TW, Li X, Thakar MS, Zhang J, Malarkannan S. Transforming growth factor-beta-activated kinase 1 regulates natural killer cell-mediated cytotoxicity and cytokine production. J Biol Chem. 2011 Sep 9;286(36):31213-24,PMCID:PMC317306
11. Chen Y, Fukuda T, Thakar MS, Kornblit BT, Storer BE, Santos EB, Storb R, Sandmaier BM. Immunomodulatory effects induced by cytotoxic T lymphocyte antigen 4 immunoglobulin with donor peripheral blood mononuclear cell infusion in canine major histocompatibility complex-haplo-identical non-myeloablative hematopoietic cell transplantation. Cytotherapy. 2011 Nov;13(10):1269-80,PMCID:PMC3195840
12. Malarkannan S, Awasthi A, Rajasekaran K, Kumar P, Schuldt KM, Bartoszek A, Manoharan N, Goldner NK, Umhoefer CM, Thakar MS. IQGAP1: A Regulator of Intracellular Spacetime Relativity. J Immunol. 2012 Mar 1;188(5):2057-63,PMCID:PMC3286039
13. Kumar P, Bartoszek AE, Moran TM, Gorski J, Bhattacharyya S, Navidad JF, Thakar MS, Malarkannan S. High-throughput Detection Method for Influenza Virus. J Vis Exp. 2012 Feb 4;(60)e3623,PMCID:PMC3195840.
14. Verbsky J, Thakar M, Routes J. The Wisconsin approach to newborn screening for severe combined immunodeficiency. J Allergy Clin Immunol. 2012 Mar;129(3):622-7,PMID: 22244594
15. Palmer JM, Rajasekaran K, Thakar MS, Malarkannan S Clinical relevance of natural killer cells following hematopoietic stem cell transplantation. J Cancer. 2013;4(1):25-35,PMCID:PMC3564244
16. Kumar P, Rajasekaran K, Palmer JM, Thakar MS, Malarkannan S IL-22: An Evolutionary Missing-Link Authenticating the Role of the Immune System in Tissue Regeneration. J Cancer. 2013;4(1):57-65,PMCID:PMC3564247
17. Ayas M, Saber W, Davies SM, Harris RE, Hale GA, Socie G, Lerademacher J, Thakar M, Deeg HJ, Al-Seraihy A, Battiwalla M, Camitta BM, Olsson R, Bajwa RS, Bonfim CM, Pasquini R, Macmillan ML, George B, Copelan EA, Wirk B, Al Jefri A, Fasth AL, Guinan EC, Horn BN, Lewis VA, Slavin S, Stepensky P, Bierings M, Gale RP Allogeneic Hematopoietic Cell Transplantation for Fanconi Anemia in Patients With Pretransplantation Cytogenetic Abnormalities, Myelodysplastic Syndrome, or Acute Leukemia. J Clin Oncol. 2013 Apr 1,PMCID: PMC3635221
18. Thakar MS, Bonfim C, Sandmaier BM, O'Donnell P, Ribeiro L, Gooley T, Deeg HJ, Flowers ME, Pasquini R, Storb R, Woolfrey AE, Kiem HP Cyclophosphamide-based in vivo T-cell depletion for HLA-haploidentical transplantation in Fanconi anemia. Pediatr Hematol Oncol. 2012 Sep;29(6):568-78,PMCID:PMC3622043
19. Kumar P, Thakar MS, Ouyang W, Malarkannan S IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection. Mucosal Immunol. 2013 Jan;6(1):69-82,PMCID:PMC3835350
20. Rajasekaran K, Kumar P, Schuldt KM, Peterson EJ, Vanhaesebroeck B, Dixit V, Thakar MS, Malarkannan S Corrigendum: Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells. Nat Immunol. 2014 Feb;15(2):205,PMCID: PMC3855032
21. Kumar P, Bartoszek AE, Moran TM, Gorski J, Bhattacharyya S, Navidad JF, Thakar MS, Malarkannan S High-throughput detection method for influenza virus. J Vis Exp. 2012(60): PMCID: PMC3369630
22. Burroughs LM, Nemecek ER, Torgerson TR, Storer BE, Talano JA, Domm J, Giller RH, Shimamura A, Delaney C, Skoda-Smith S, Thakar MS, Baker KS, Rawlings DJ, Englund JA, Flowers ME, Deeg HJ, Storb R, Woolfrey AE Treosulfan-Based Conditioning and Hematopoietic Cell Transplantation for Nonmalignant Diseases: A Prospective Multi-Center Trial. Biol Blood Marrow Transplant. 2014 Sep 4:
 
Books, Chapters, and Reviews
1. Malarkannan S, Awasthi T, Rajasekaran K, Kumar P, Schuldt KM, Bartoszek A, Manoharan N, Goldner NK, Umhoefer CM, Thakar MS. IQGAP1: A Regulator of Intracellular Spacetime Relativity. J Immunol. 2012 Mar 1;188(5):2057-63
 
Abstracts
1. Thakar MS, Liedel JL, Rubin CM, Brown M, Bacha EA, Kahana MD. FVIIa for peri-operative bleeding in the PICU and NICU. PAS Annual Meeting Program with Abstracts-on-Line. 2004 May;Abstract #1749:http://www.abstracts2view.com/pasall/view.php?nu=PAS4L1_3128
2. Thakar MS, Gooley TA, Santos EB, Storb RF, Sandmaier BM. High-Dose Methotrexate as Part of a Novel Immunosuppressive Regimen in Canine MHC-Haploidentical Hematopoietic Cell Transplantation. Blood (ASH Annual Meeting Abstracts). 2006 Nov;108:3180
3. Thakar MS, Storer B, Chauncey T, MD, Pulsipher M, Maloney D, Storb R, Sandmaier B. Reversal of Low Chimerism Following Nonmyeloablative Hematopoietic Cell Transplantation Using Pentostatin and Donor Lymphocyte Infusions. Blood (ASH Annual Meeting Abstracts). 2007 Nov;110:480
4. Wilbur D, Hamilin D, Nakamae H, Thakar MS, Santos E, Pantelias A, Kenoyer A, Pagel J, Press O, Storb R, Sandmaier B. Comparison of biodistributions, myelosuppression and toxicity in mice of an anti-CD45 antibody labeled with the α-emitters 213Bi or 211At. AACR Meeting Abstracts. 2008 Apr;2008:3160
5. Nakamae H, Wilbur D, Hamlin D, Thakar MS, Santos E, Fisher D, Kenoyer A, Pagel J, Press O, Storb R, Sandmaier B. Evaluation of Toxicity and Tissue Radiation Doses obtained in Mice with an Anti-CD45 Monoclonal Antibody (mAb) labeled with the Alpha-Emitting Radionuclides, Astatine-211 or Bismuth-213. Blood (ASH Annual Meeting Abstracts). 2008 Nov;112:3270
6. Thakar MS, Storer B, Storb R, Shizuru J, Niederwieser D, Pulsipher M, Sahebi F, Sorror M, Chen Y, Georges G, Maloney D, Woolfrey A, Sandmaier B. Treatment of pediatric high-risk malignancies using non-myeloablative (NM) hematopoietic cell transplantation (HCT): a multi-institutional experience. Biology of Blood and Marrow Transplantation. 2010 Feb;16,(2, Suppl 2):S246-S247.
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