Alan S. Bloom PhD Online Profile
Professor
Medical College of Wisconsin
Department: Pharmacology and Toxicology
Program: Pharmacology

Publications
Responses of dopaminergic, serotonergic and noradrenergic networks to acute levo-tetrahydropalmatine administration in naïve rats detected at 9.4 T. (Liu X, Yang Z, Li R, Xie J, Yin Q, Bloom AS, Li SJ) Magn Reson Imaging 2012 Feb;30(2):261-70 PMID 22079072 Neural responses to acute cocaine administration in the human brain detected by fMRI. (Kufahl PR, Li Z, Risinger RC, Rainey CJ, Wu G, Bloom AS, Li SJ) Neuroimage 2005 Dec;28(4):904-14 PMID 16061398 Neural correlates of high and craving during cocaine self-administration using BOLD fMRI. (Risinger RC, Salmeron BJ, Ross TJ, Amen SL, Sanfilipo M, Hoffmann RG, Bloom AS, Garavan H, Stein EA) Neuroimage 2005 Jul 15;26(4):1097-108 PMID 15886020 Hepatitis C virus infection in cocaine users--a silent epidemic. (Harsch HH, Pankiewicz J, Bloom AS, Rainey C, Cho JK, Sperry L, Stein EA) Community Ment Health J 2000 Jun;36(3):225-33 PMID 10933240 Determination of drug-induced changes in functional MRI signal using a pharmacokinetic model. (Bloom AS, Hoffmann RG, Fuller SA, Pankiewicz J, Harsch HH, Stein EA) Hum Brain Mapp 1999;8(4):235-44 PMID 10619417 Nicotine-induced limbic cortical activation in the human brain: a functional MRI study. (Stein EA, Pankiewicz J, Harsch HH, Cho JK, Fuller SA, Hoffmann RG, Hawkins M, Rao SM, Bandettini PA, Bloom AS) Am J Psychiatry 1998 Aug;155(8):1009-15 PMID 9699686 Cannabinoid-induced alterations in regional cerebral blood flow in the rat. (Bloom AS, Tershner S, Fuller SA, Stein EA) Pharmacol Biochem Behav 1997 Aug;57(4):625-31 PMID 9258987 Nonclassical and endogenous cannabinoids: effects on the ordering of brain membranes. (Bloom AS, Edgemond WS, Moldvan JC) Neurochem Res 1997 May;22(5):563-8 PMID 9131634 Leukocyte hexokinase activity in aging and Alzheimer disease. (Antuono PG, Ravanelli-Meyer J, Nicholson K, Bloom AS) Dementia 1995 Jul-Aug;6(4):200-4 PMID 7550599 Cannabinoid-like effects of aminoalkylindole compounds on the physical properties of brain membranes: fluorescence polarization studies. (Moldovan JC, Ward SJ, Bloom AS) NIDA Res Monogr 1990;105:302-3 PMID 1876019 Interactions of flavins with melanin. Studies on equilibrium binding of riboflavin to dopa-melanin and some spectroscopic characteristics of flavin-melanin complex. (Kozik A, Korytowski W, Sarna T, Bloom AS) Biophys Chem 1990 Oct;38(1-2):39-48 PMID 2128193 Studies of the role of membrane lipid order in the effects of delta 9-tetrahydrocannabinol on adenylate cyclase activation in heart. (Hillard CJ, Pounds JJ, Boyer DR, Bloom AS) J Pharmacol Exp Ther 1990 Mar;252(3):1075-82 PMID 2156989 Effects of pyrethroid insecticides on operant responding maintained by food. (Stein EA, Washburn M, Walczak C, Bloom AS) Neurotoxicol Teratol 1987 Jan-Feb;9(1):27-31 PMID 3627076 Effects of delta 9-tetrahydrocannabinol on glucagon receptor coupling to adenylate cyclase in rat liver plasma membranes. (Hillard CJ, Bloom AS, Houslay MD) Biochem Pharmacol 1986 Aug 15;35(16):2797-803 PMID 3017362 Effects of the cannabinoids on physical properties of brain membranes and phospholipid vesicles: fluorescence studies. (Hillard CJ, Harris RA, Bloom AS) J Pharmacol Exp Ther 1985 Mar;232(3):579-88 PMID 2983062 Possible noradrenergic involvement in naloxone potentiation of apomorphine-induced stereotypic climbing in mice. (Quock RM, Bloom AS, Sadowski JA) Pharmacol Biochem Behav 1984 Nov;21(5):733-6 PMID 6096896 The effects of delta 9-tetrahydrocannabinol on serum thyrotropin levels in the rat. (Hillard CJ, Farber NE, Hagen TC, Bloom AS) Pharmacol Biochem Behav 1984 Apr;20(4):547-50 PMID 6328543 Possible role of prostaglandins in the effects of the cannabinoids on adenylate cyclase activity. (Hillard CJ, Bloom AS) Eur J Pharmacol 1983 Jul 15;91(1):21-7 PMID 6311573 Pyrethroid effects on operant responding and feeding. (Bloom AS, Staatz CG, Dieringer T) Neurobehav Toxicol Teratol 1983 May-Jun;5(3):321-4 PMID 6877472 Effect of pyrethroids on [3H]kainic acid binding to mouse forebrain membranes. (Staatz CG, Bloom AS, Lech JJ) Toxicol Appl Pharmacol 1982 Jul;64(3):566-9 PMID 7135402 Effect of delta9-tetrahydrocannabinol on the synthesis of dopamine and norepinephrine in mouse brain synaptosomes. (Bloom AS) J Pharmacol Exp Ther 1982 Apr;221(1):97-103 PMID 6278139 delta 9-Tetrahydrocannabinol-induced changes in beta-adrenergic receptor binding in mouse cerebral cortex. (Hillard CJ, Bloom AS) Brain Res 1982 Mar 11;235(2):370-7 PMID 6329417 Endogenous norepinephrine release induced by tyramine modulates intestinal ion transport. (Tapper EJ, Bloom AS, Lewand DL) Am J Physiol 1981 Sep;241(3):G264-9 PMID 7282935 Effect of intraventricular beta-endorphin and morphine on hypothalamic-pituitary-adrenal activity and the release of pituitary beta-endorphin. (Haracz JL, Bloom AS, Wang RI, Tseng LF) Neuroendocrinology 1981 Sep;33(3):170-5 PMID 6270585 Adrenalectomy reverses the effects of delta-9-THC on mouse brain 5-hydroxytryptamine turnover. (Johnson KM, Dewey WL, Bloom AS) Pharmacology 1981;23(4):223-9 PMID 6275421 Effects of beta-endorphin on body temperature in mice at different ambient temperatures. (Bloom AS, Tseng LF) Peptides 1981;2(3):293-7 PMID 6272245 Interaction of ambient temperature with the effects of delta 9-tetrahydrocannabinol on brain catecholamine synthesis and plasma corticosterone levels. (Bloom AS, Kiernan CJ) Psychopharmacology (Berl) 1980;67(3):215-9 PMID 6247738 Effects of delta9-tetrahydrocannabinol on ATPases in mouse brain subcellular fractions. (Bloom AS, Haavik CO, Strehlow D) Life Sci 1978 Oct 2;23(13):1399-404 PMID 214649 A comparison of some pharmacological actions of morphine and delta9-tetrahydrocannabinol in the mouse. (Bloom AS, Dewey WL) Psychopharmacology (Berl) 1978 May 31;57(3):243-8 PMID 97703 The effects of cannabinoids on body temperature and brain catecholamine synthesis. (Bloom AS, Johnson KM, Dewey WL) Res Commun Chem Pathol Pharmacol 1978 Apr;20(1):51-7 PMID 663408 Effects of d-amphetamine and strychnine on cycloheximide- and diethyldithiocarbamate-induced amnesia in mice. (Quinton EE, Bloom AS) J Comp Physiol Psychol 1977 Dec;91(6):1390-7 PMID 202616 Effects of cycloheximide, diethyldithiocarbamate and D-amphetamine on protein and catecholamine biosynthesis in mouse brain. (Bloom AS, Quinton EE, Carr LA) Neuropharmacology 1977 Jun;16(6):411-8 PMID 198698 9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine. (Bloom AS, Dewey WL, Harris LS, Brosius KK) J Pharmacol Exp Ther 1977 Feb;200(2):263-70 PMID 839438 The correlation between antinociceptive activity of narcotics and their antagonists as measured in the mouse tail-flick test and increased synthesis of brain catecholamines. (Bloom AS, Dewey WL, Harris LS, Brosius KK) J Pharmacol Exp Ther 1976 Jul;198(1):33-41 PMID 6793 Interactions of active constituents of marihuana with other drugs in the neuron. (Dewey WL, Johnson KM, Bloom AS) Ann N Y Acad Sci 1976;281:190-7 PMID 798522 Grants and Awards
Imaging Studies in Neurotoxicity and Neurodevelopment (#9204815 09/01/2007 - 08/31/2008) Sponsor: University of Hawaii at ManoaInvestigating Cortical Function in Chronic Cannabis (#9206514 09/01/2010 - 08/31/2013) Sponsor: University of Hawaii at ManoaEffects of Doxorubicin on Brain Function in a Rodent Model of Breast Cancer (#9207679 09/01/2012 - 02/28/2014) Sponsor: United Negro College Fund