Medical College of Wisconsin
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Alan S. Bloom PhD

Alan S. Bloom PhD


Institution: Medical College of Wisconsin
Department: Pharmacology and Toxicology
Program: Pharmacology

Member of the Cancer Center


  • Responses of dopaminergic, serotonergic and noradrenergic networks to acute levo-tetrahydropalmatine administration in na├»ve rats detected at 9.4 T. (Liu X, Yang Z, Li R, Xie J, Yin Q, Bloom AS, Li SJ) Magn Reson Imaging 2012 Feb;30(2):261-70 PMID 22079072
  • Neural responses to acute cocaine administration in the human brain detected by fMRI. (Kufahl PR, Li Z, Risinger RC, Rainey CJ, Wu G, Bloom AS, Li SJ) Neuroimage 2005 Dec;28(4):904-14 PMID 16061398
  • Neural correlates of high and craving during cocaine self-administration using BOLD fMRI. (Risinger RC, Salmeron BJ, Ross TJ, Amen SL, Sanfilipo M, Hoffmann RG, Bloom AS, Garavan H, Stein EA) Neuroimage 2005 Jul 15;26(4):1097-108 PMID 15886020
  • Hepatitis C virus infection in cocaine users--a silent epidemic. (Harsch HH, Pankiewicz J, Bloom AS, Rainey C, Cho JK, Sperry L, Stein EA) Community Ment Health J 2000 Jun;36(3):225-33 PMID 10933240
  • Determination of drug-induced changes in functional MRI signal using a pharmacokinetic model. (Bloom AS, Hoffmann RG, Fuller SA, Pankiewicz J, Harsch HH, Stein EA) Hum Brain Mapp 1999;8(4):235-44 PMID 10619417
  • Nicotine-induced limbic cortical activation in the human brain: a functional MRI study. (Stein EA, Pankiewicz J, Harsch HH, Cho JK, Fuller SA, Hoffmann RG, Hawkins M, Rao SM, Bandettini PA, Bloom AS) Am J Psychiatry 1998 Aug;155(8):1009-15 PMID 9699686
  • Cannabinoid-induced alterations in regional cerebral blood flow in the rat. (Bloom AS, Tershner S, Fuller SA, Stein EA) Pharmacol Biochem Behav 1997 Aug;57(4):625-31 PMID 9258987
  • Nonclassical and endogenous cannabinoids: effects on the ordering of brain membranes. (Bloom AS, Edgemond WS, Moldvan JC) Neurochem Res 1997 May;22(5):563-8 PMID 9131634
  • Leukocyte hexokinase activity in aging and Alzheimer disease. (Antuono PG, Ravanelli-Meyer J, Nicholson K, Bloom AS) Dementia 1995 Jul-Aug;6(4):200-4 PMID 7550599
  • Cannabinoid-like effects of aminoalkylindole compounds on the physical properties of brain membranes: fluorescence polarization studies. (Moldovan JC, Ward SJ, Bloom AS) NIDA Res Monogr 1990;105:302-3 PMID 1876019
  • Interactions of flavins with melanin. Studies on equilibrium binding of riboflavin to dopa-melanin and some spectroscopic characteristics of flavin-melanin complex. (Kozik A, Korytowski W, Sarna T, Bloom AS) Biophys Chem 1990 Oct;38(1-2):39-48 PMID 2128193
  • Studies of the role of membrane lipid order in the effects of delta 9-tetrahydrocannabinol on adenylate cyclase activation in heart. (Hillard CJ, Pounds JJ, Boyer DR, Bloom AS) J Pharmacol Exp Ther 1990 Mar;252(3):1075-82 PMID 2156989
  • Effects of pyrethroid insecticides on operant responding maintained by food. (Stein EA, Washburn M, Walczak C, Bloom AS) Neurotoxicol Teratol 1987 Jan-Feb;9(1):27-31 PMID 3627076
  • Effects of delta 9-tetrahydrocannabinol on glucagon receptor coupling to adenylate cyclase in rat liver plasma membranes. (Hillard CJ, Bloom AS, Houslay MD) Biochem Pharmacol 1986 Aug 15;35(16):2797-803 PMID 3017362
  • Effects of the cannabinoids on physical properties of brain membranes and phospholipid vesicles: fluorescence studies. (Hillard CJ, Harris RA, Bloom AS) J Pharmacol Exp Ther 1985 Mar;232(3):579-88 PMID 2983062
  • Possible noradrenergic involvement in naloxone potentiation of apomorphine-induced stereotypic climbing in mice. (Quock RM, Bloom AS, Sadowski JA) Pharmacol Biochem Behav 1984 Nov;21(5):733-6 PMID 6096896
  • The effects of delta 9-tetrahydrocannabinol on serum thyrotropin levels in the rat. (Hillard CJ, Farber NE, Hagen TC, Bloom AS) Pharmacol Biochem Behav 1984 Apr;20(4):547-50 PMID 6328543
  • Possible role of prostaglandins in the effects of the cannabinoids on adenylate cyclase activity. (Hillard CJ, Bloom AS) Eur J Pharmacol 1983 Jul 15;91(1):21-7 PMID 6311573
  • Pyrethroid effects on operant responding and feeding. (Bloom AS, Staatz CG, Dieringer T) Neurobehav Toxicol Teratol 1983 May-Jun;5(3):321-4 PMID 6877472
  • Effect of pyrethroids on [3H]kainic acid binding to mouse forebrain membranes. (Staatz CG, Bloom AS, Lech JJ) Toxicol Appl Pharmacol 1982 Jul;64(3):566-9 PMID 7135402
  • Effect of delta9-tetrahydrocannabinol on the synthesis of dopamine and norepinephrine in mouse brain synaptosomes. (Bloom AS) J Pharmacol Exp Ther 1982 Apr;221(1):97-103 PMID 6278139
  • delta 9-Tetrahydrocannabinol-induced changes in beta-adrenergic receptor binding in mouse cerebral cortex. (Hillard CJ, Bloom AS) Brain Res 1982 Mar 11;235(2):370-7 PMID 6329417
  • Endogenous norepinephrine release induced by tyramine modulates intestinal ion transport. (Tapper EJ, Bloom AS, Lewand DL) Am J Physiol 1981 Sep;241(3):G264-9 PMID 7282935
  • Effect of intraventricular beta-endorphin and morphine on hypothalamic-pituitary-adrenal activity and the release of pituitary beta-endorphin. (Haracz JL, Bloom AS, Wang RI, Tseng LF) Neuroendocrinology 1981 Sep;33(3):170-5 PMID 6270585
  • Adrenalectomy reverses the effects of delta-9-THC on mouse brain 5-hydroxytryptamine turnover. (Johnson KM, Dewey WL, Bloom AS) Pharmacology 1981;23(4):223-9 PMID 6275421
  • Effects of beta-endorphin on body temperature in mice at different ambient temperatures. (Bloom AS, Tseng LF) Peptides 1981;2(3):293-7 PMID 6272245
  • Interaction of ambient temperature with the effects of delta 9-tetrahydrocannabinol on brain catecholamine synthesis and plasma corticosterone levels. (Bloom AS, Kiernan CJ) Psychopharmacology (Berl) 1980;67(3):215-9 PMID 6247738
  • Effects of delta9-tetrahydrocannabinol on ATPases in mouse brain subcellular fractions. (Bloom AS, Haavik CO, Strehlow D) Life Sci 1978 Oct 2;23(13):1399-404 PMID 214649
  • A comparison of some pharmacological actions of morphine and delta9-tetrahydrocannabinol in the mouse. (Bloom AS, Dewey WL) Psychopharmacology (Berl) 1978 May 31;57(3):243-8 PMID 97703
  • The effects of cannabinoids on body temperature and brain catecholamine synthesis. (Bloom AS, Johnson KM, Dewey WL) Res Commun Chem Pathol Pharmacol 1978 Apr;20(1):51-7 PMID 663408
  • Effects of d-amphetamine and strychnine on cycloheximide- and diethyldithiocarbamate-induced amnesia in mice. (Quinton EE, Bloom AS) J Comp Physiol Psychol 1977 Dec;91(6):1390-7 PMID 202616
  • Effects of cycloheximide, diethyldithiocarbamate and D-amphetamine on protein and catecholamine biosynthesis in mouse brain. (Bloom AS, Quinton EE, Carr LA) Neuropharmacology 1977 Jun;16(6):411-8 PMID 198698
  • 9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine. (Bloom AS, Dewey WL, Harris LS, Brosius KK) J Pharmacol Exp Ther 1977 Feb;200(2):263-70 PMID 839438
  • The correlation between antinociceptive activity of narcotics and their antagonists as measured in the mouse tail-flick test and increased synthesis of brain catecholamines. (Bloom AS, Dewey WL, Harris LS, Brosius KK) J Pharmacol Exp Ther 1976 Jul;198(1):33-41 PMID 6793
  • Interactions of active constituents of marihuana with other drugs in the neuron. (Dewey WL, Johnson KM, Bloom AS) Ann N Y Acad Sci 1976;281:190-7 PMID 798522
  • Grants and Awards

  • Imaging Studies in Neurotoxicity and Neurodevelopment (#9204815 09/01/2007 - 08/31/2008) Sponsor: University of Hawaii at Manoa
  • Last update: 06/16/2014