Medical College of Wisconsin
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Daisy Sahoo PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Endocrinology
Program: Administration


Publications

  • Functional genomics of the human high-density lipoprotein receptor scavenger receptor BI: an old dog with new tricks. (Chadwick AC, Sahoo D) Curr Opin Endocrinol Diabetes Obes 2013 Apr;20(2):124-31 PMID 23403740
  • Functional characterization of newly-discovered mutations in human SR-BI. (Chadwick AC, Sahoo D) PLoS One 2012;7(9):e45660 PMID 23029167
  • Cholesterol and lipoprotein dynamics in a hibernating mammal. (Otis JP, Sahoo D, Drover VA, Yen CL, Carey HV) PLoS One 2011;6(12):e29111 PMID 22195001
  • Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport. (Papale GA, Hanson PJ, Sahoo D) Biochemistry 2011 Jul 19;50(28):6245-54 PMID 21675794
  • Extracellular hydrophobic regions in scavenger receptor BI play a key role in mediating HDL-cholesterol transport. (Papale GA, Nicholson K, Hanson PJ, Pavlovic M, Drover VA, Sahoo D) Arch Biochem Biophys 2010 Apr 15;496(2):132-9 PMID 20219439
  • CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice. (Drover VA, Nguyen DV, Bastie CC, Darlington YF, Abumrad NA, Pessin JE, London E, Sahoo D, Phillips MC) J Biol Chem 2008 May 9;283(19):13108-15 PMID 18332148
  • Scavenger receptor class B, type I (SR-BI) homo-dimerizes via its C-terminal region: fluorescence resonance energy transfer analysis. (Sahoo D, Peng Y, Smith JR, Darlington YF, Connelly MA) Biochim Biophys Acta 2007 Jul;1771(7):818-29 PMID 17556017
  • Scavenger receptor class B Type I (SR-BI) assembles into detergent-sensitive dimers and tetramers. (Sahoo D, Darlington YF, Pop D, Williams DL, Connelly MA) Biochim Biophys Acta 2007 Jul;1771(7):807-17 PMID 16624615
  • CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. (Drover VA, Ajmal M, Nassir F, Davidson NO, Nauli AM, Sahoo D, Tso P, Abumrad NA) J Clin Invest 2005 May;115(5):1290-7 PMID 15841205
  • Glycine 420 near the C-terminal transmembrane domain of SR-BI is critical for proper delivery and metabolism of high density lipoprotein cholesteryl ester. (Parathath S, Sahoo D, Darlington YF, Peng Y, Collins HL, Rothblat GH, Williams DL, Connelly MA) J Biol Chem 2004 Jun 11;279(24):24976-85 PMID 15060063
  • ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes. (Sahoo D, Trischuk TC, Chan T, Drover VA, Ho S, Chimini G, Agellon LB, Agnihotri R, Francis GA, Lehner R) J Lipid Res 2004 Jun;45(6):1122-31 PMID 14993246
  • Apolipoprotein A-II regulates HDL stability and affects hepatic lipase association and activity. (Boucher J, Ramsamy TA, Braschi S, Sahoo D, Neville TA, Sparks DL) J Lipid Res 2004 May;45(5):849-58 PMID 14967812
  • Lipid-triggered conformational switch of apolipophorin III helix bundle to an extended helix organization. (Sahoo D, Weers PM, Ryan RO, Narayanaswami V) J Mol Biol 2002 Aug 9;321(2):201-14 PMID 12144779
  • Pyrene excimer fluorescence: a spatially sensitive probe to monitor lipid-induced helical rearrangement of apolipophorin III. (Sahoo D, Narayanaswami V, Kay CM, Ryan RO) Biochemistry 2000 Jun 6;39(22):6594-601 PMID 10828977
  • NMR evidence for a conformational adaptation of apolipophorin III upon lipid association. (Wang J, Sahoo D, Sykes BD, Ryan RO) Biochem Cell Biol 1998;76(2-3):276-83 PMID 9923696
  • Fluorescence studies of exchangeable apolipoprotein-lipid interactions. Superficial association of apolipophorin III with lipoprotein surfaces. (Sahoo D, Narayanaswami V, Kay CM, Ryan RO) J Biol Chem 1998 Jan 16;273(3):1403-8 PMID 9430675
  • Grants and Awards

  • Selective Uptake of Hydrolysis of Cholesteryl Ester by SR-BI (#9204507 04/01/2007 - 03/31/2010) Sponsor: NIH Heart Lung and Blood Institute
  • Characterization of Interactions Between HDL and SR-BI (#9208392 01/01/2014 - 12/31/2015) Sponsor: American Heart Association - Midwest Affiliate
  • Selective Uptake and Hydrolysis of Cholesteryl Ester by SR-BI (#9206176 04/01/2010 - 02/28/2015) Sponsor: NIH Heart Lung and Blood Institute