David M. Gourlay MD Online Profile

David M. Gourlay MD

Associate Professor
Medical College of Wisconsin
Department: Surgery
Division: Pediatric Surgery


Leadership Positions

  • Wisconsin State Trauma Advisory Committee
  • American Pediatric Surgical Association - Trauma Committee
  • Medical Director - Trauma Program Children's Hopsital of Wisconsin
  • Association of American Medical Colleges – MCW Key Contact for Joining Forces Program
  • Publications

  • The good and the bad of the innate immune response in necrotizing enterocolitis. (Gourlay DM) J Surg Res 2012 Jun 1;175(1):51-3 PMID 21920553
  • Endothelial microparticles induce inflammation in acute lung injury. (Buesing KL, Densmore JC, Kaul S, Pritchard KA Jr, Jarzembowski JA, Gourlay DM, Oldham KT) J Surg Res 2011 Mar;166(1):32-9 PMID 20828748
  • Conservative management of giant omphalocele with topical povidone-iodine and its effect on thyroid function. (Whitehouse JS, Gourlay DM, Masonbrink AR, Aiken JJ, Calkins CM, Sato TT, Arca MJ) J Pediatr Surg 2010 Jun;45(6):1192-7 PMID 20620319
  • Is it safe to discharge intussusception patients after successful hydrostatic reduction? (Whitehouse JS, Gourlay DM, Winthrop AL, Cassidy LD, Arca MJ) J Pediatr Surg 2010 Jun;45(6):1182-6 PMID 20620317
  • The protective role of intestinal alkaline phosphatase in necrotizing enterocolitis. (Whitehouse JS, Riggle KM, Purpi DP, Mayer AN, Pritchard KA Jr, Oldham KT, Gourlay DM) J Surg Res 2010 Sep;163(1):79-85 PMID 20599220
  • The protective role of intestinal alkaline phosphatase in necrotizing enterocolitis. (Whitehouse JS et al.) J Surg Res 2010 Feb;158(2):201 PMID 20105777
  • Endothelial microparticles induce myeloperoxidase-mediated lung injury. (Buesing K et al.) J Surg Res 2010 Feb;158(2):349 PMID 20106140
  • Mesenteric nitric oxide and superoxide production in experimental necrotizing enterocolitis. (Whitehouse JS, Xu H, Shi Y, Noll L, Kaul S, Jones DW, Pritchard KA Jr, Oldham KT, Gourlay DM) J Surg Res 2010 Jun 1;161(1):1-8 PMID 19922948
  • Beyond feasibility: a comparison of newborns undergoing thoracoscopic and open repair of congenital diaphragmatic hernias. (Gourlay DM, Cassidy LD, Sato TT, Lal DR, Arca MJ) J Pediatr Surg 2009 Sep;44(9):1702-7 PMID 19735811
  • Pelvic angiography for recurrent traumatic pelvic arterial hemorrhage. (Gourlay D, Hoffer E, Routt M, Bulger E) J Trauma 2005 Nov;59(5):1168-73; discussion 1173-4 PMID 16385296
  • Implications of proteasome inhibition: an enhanced macrophage phenotype. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) Cell Immunol 2004 Feb;227(2):140-7 PMID 15135296
  • Modulation of macrophage responsiveness to lipopolysaccharide by IRAK-1 manipulation. (Cuschieri J, Bulmus V, Gourlay D, Garcia I, Hoffman A, Stayton P, Maier RV) Shock 2004 Feb;21(2):182-8 PMID 14752294
  • Modulation of endotoxin-induced endothelial function by calcium/calmodulin-dependent protein kinase. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) Shock 2003 Aug;20(2):176-82 PMID 12865664
  • Platelet-activating factor acetylhydrolase inhibits alveolar macrophage activation in vivo. (Bulger EM, Gourlay D, Cuschieri J, Jelacic S, Staudenmeyer K, Garcia I, Maier RV) Shock 2003 Jul;20(1):17-22 PMID 12813363
  • Endotoxin-induced endothelial cell proinflammatory phenotypic differentiation requires stress fiber polymerization. (Cuschleri J, Gourlay D, Garcia I, Jelacic S, Maier RV) Shock 2003 May;19(5):433-9 PMID 12744486
  • Modulation of endotoxin-induced endothelial activity by microtubule depolymerization. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) J Trauma 2003 Jan;54(1):104-12; discussion 112-3 PMID 12544905
  • Platelet-activating factor priming of inflammatory cell activity requires cellular adherence. (Cuschieri J, Gourlay D, Bulger E, Garcia I, Jelacic S, Maier RV) Surgery 2002 Aug;132(2):157-66 PMID 12219006
  • Slow channel calcium inhibition blocks proinflammatory gene signaling and reduces macrophage responsiveness. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) J Trauma 2002 Mar;52(3):434-42 PMID 11901316
  • Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) J Immunol 2002 Feb 1;168(3):1389-96 PMID 11801680
  • Grants and Awards

  • Clinical and Translational Science Institute (#9520094 10/01/2007 - 09/30/2014) PI of Protective Role of Intestinal Alkaline Phosphatase in Necrotizing Enterocolitis (#5520167)