David M. Gourlay MD Online Profile
Associate Professor
Medical College of Wisconsin
Department: Surgery
Division: Pediatric Surgery

Leadership Positions
Wisconsin State Trauma Advisory CommitteeAmerican Pediatric Surgical Association - Trauma CommitteeMedical Director - Trauma Program Children's Hopsital of WisconsinAssociation of American Medical Colleges – MCW Key Contact for Joining Forces ProgramPublications
The good and the bad of the innate immune response in necrotizing enterocolitis. (Gourlay DM) J Surg Res 2012 Jun 1;175(1):51-3 PMID 21920553 Endothelial microparticles induce inflammation in acute lung injury. (Buesing KL, Densmore JC, Kaul S, Pritchard KA Jr, Jarzembowski JA, Gourlay DM, Oldham KT) J Surg Res 2011 Mar;166(1):32-9 PMID 20828748 Conservative management of giant omphalocele with topical povidone-iodine and its effect on thyroid function. (Whitehouse JS, Gourlay DM, Masonbrink AR, Aiken JJ, Calkins CM, Sato TT, Arca MJ) J Pediatr Surg 2010 Jun;45(6):1192-7 PMID 20620319 Is it safe to discharge intussusception patients after successful hydrostatic reduction? (Whitehouse JS, Gourlay DM, Winthrop AL, Cassidy LD, Arca MJ) J Pediatr Surg 2010 Jun;45(6):1182-6 PMID 20620317 The protective role of intestinal alkaline phosphatase in necrotizing enterocolitis. (Whitehouse JS, Riggle KM, Purpi DP, Mayer AN, Pritchard KA Jr, Oldham KT, Gourlay DM) J Surg Res 2010 Sep;163(1):79-85 PMID 20599220 The protective role of intestinal alkaline phosphatase in necrotizing enterocolitis. (Whitehouse JS et al.) J Surg Res 2010 Feb;158(2):201 PMID 20105777 Endothelial microparticles induce myeloperoxidase-mediated lung injury. (Buesing K et al.) J Surg Res 2010 Feb;158(2):349 PMID 20106140 Mesenteric nitric oxide and superoxide production in experimental necrotizing enterocolitis. (Whitehouse JS, Xu H, Shi Y, Noll L, Kaul S, Jones DW, Pritchard KA Jr, Oldham KT, Gourlay DM) J Surg Res 2010 Jun 1;161(1):1-8 PMID 19922948 Beyond feasibility: a comparison of newborns undergoing thoracoscopic and open repair of congenital diaphragmatic hernias. (Gourlay DM, Cassidy LD, Sato TT, Lal DR, Arca MJ) J Pediatr Surg 2009 Sep;44(9):1702-7 PMID 19735811 Pelvic angiography for recurrent traumatic pelvic arterial hemorrhage. (Gourlay D, Hoffer E, Routt M, Bulger E) J Trauma 2005 Nov;59(5):1168-73; discussion 1173-4 PMID 16385296 Implications of proteasome inhibition: an enhanced macrophage phenotype. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) Cell Immunol 2004 Feb;227(2):140-7 PMID 15135296 Modulation of macrophage responsiveness to lipopolysaccharide by IRAK-1 manipulation. (Cuschieri J, Bulmus V, Gourlay D, Garcia I, Hoffman A, Stayton P, Maier RV) Shock 2004 Feb;21(2):182-8 PMID 14752294 Modulation of endotoxin-induced endothelial function by calcium/calmodulin-dependent protein kinase. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) Shock 2003 Aug;20(2):176-82 PMID 12865664 Platelet-activating factor acetylhydrolase inhibits alveolar macrophage activation in vivo. (Bulger EM, Gourlay D, Cuschieri J, Jelacic S, Staudenmeyer K, Garcia I, Maier RV) Shock 2003 Jul;20(1):17-22 PMID 12813363 Endotoxin-induced endothelial cell proinflammatory phenotypic differentiation requires stress fiber polymerization. (Cuschleri J, Gourlay D, Garcia I, Jelacic S, Maier RV) Shock 2003 May;19(5):433-9 PMID 12744486 Modulation of endotoxin-induced endothelial activity by microtubule depolymerization. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) J Trauma 2003 Jan;54(1):104-12; discussion 112-3 PMID 12544905 Platelet-activating factor priming of inflammatory cell activity requires cellular adherence. (Cuschieri J, Gourlay D, Bulger E, Garcia I, Jelacic S, Maier RV) Surgery 2002 Aug;132(2):157-66 PMID 12219006 Slow channel calcium inhibition blocks proinflammatory gene signaling and reduces macrophage responsiveness. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) J Trauma 2002 Mar;52(3):434-42 PMID 11901316 Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin. (Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV) J Immunol 2002 Feb 1;168(3):1389-96 PMID 11801680 Grants and Awards
Clinical and Translational Science Institute (#9520094 10/01/2007 - 09/30/2014) PI of Protective Role of Intestinal Alkaline Phosphatase in Necrotizing Enterocolitis (#5520167)