Hershel Raff PhD Online Profile
Professor
Medical College of Wisconsin
Department: Medicine
Division: Endocrinology
Program: Administration

Publications
Effects of Age on ACTH, Corticosterone, Glucose, Insulin, and mRNA Levels during Intermittent Hypoxia in the Neonatal Rat. (Chintamaneni K, Bruder ED, Raff H) Am J Physiol Regul Integr Comp Physiol 2013 Mar 13: PMID 23485866 Comparison of the effectiveness of two protocols for treating nursing home residents with advanced dementia. (Kovach CR, Simpson MR, Joosse L, Logan BR, Noonan PE, Reynolds SA, Woods DL, Raff H) Res Gerontol Nurs 2012 Oct;5(4):251-63 PMID 22998656 Circadian rhythm of salivary cortisol in infants with congenital heart disease. (Caprirolo G, Ghanayem NS, Murkowski K, Nugent ML, Simpson PM, Raff H) Endocrine 2013 Feb;43(1):214-8 PMID 22976914 The realities of salivary cortisol sampling in the real world: Reply to the Letter to the Editor from Belaya and Melnichenko. (Raff H) Endocrine 2012 Aug;42(1):224-5 PMID 22638613 Salivary cortisol and the diagnosis of Cushing's syndrome: a coming of age. (Raff H) Endocrine 2012 Jun;41(3):353-4 PMID 22457047 Measurement of late-night salivary cortisol and cortisone by LC-MS/MS to assess preanalytical sample contamination with topical hydrocortisone. (Raff H, Singh RJ) Clin Chem 2012 May;58(5):947-8 PMID 22377529 Effects of body temperature maintenance on glucose, insulin, and corticosterone responses to acute hypoxia in the neonatal rat. (Guenther MA, Bruder ED, Raff H) Am J Physiol Regul Integr Comp Physiol 2012 Mar 1;302(5):R627-33 PMID 22160542 Prolactin as a marker of successful catheterization during IPSS in patients with ACTH-dependent Cushing's syndrome. (Sharma ST, Raff H, Nieman LK) J Clin Endocrinol Metab 2011 Dec;96(12):3687-94 PMID 22031511 Cushing's syndrome: diagnosis and surveillance using salivary cortisol. (Raff H) Pituitary 2012 Mar;15(1):64-70 PMID 21833616 Salivary cortisol increases after bariatric surgery in women. (Valentine AR, Raff H, Liu H, Ballesteros M, Rose JM, Jossart GH, Cirangle P, Bravata DM) Horm Metab Res 2011 Jul;43(8):587-90 PMID 21667427 Salivary cortisol in obstructive sleep apnea: the effect of CPAP. (Raff H, Ettema SL, Eastwood DC, Woodson BT) Endocrine 2011 Aug;40(1):137-9 PMID 21519909 Diurnal variation of cortisol in people with dementia: relationship to cognition and illness burden. (Kovach CR, Woods DL, Logan BR, Raff H) Am J Alzheimers Dis Other Demen 2011 Mar;26(2):145-50 PMID 21273205 Effect of animal facility construction on basal hypothalamic-pituitary-adrenal and renin-aldosterone activity in the rat. (Raff H, Bruder ED, Cullinan WE, Ziegler DR, Cohen EP) Endocrinology 2011 Apr;152(4):1218-21 PMID 21248141 Adrenocorticotropic hormone and corticosterone responses to acute hypoxia in the neonatal rat: effects of body temperature maintenance. (Bruder ED, Kamer KJ, Guenther MA, Raff H) Am J Physiol Regul Integr Comp Physiol 2011 Mar;300(3):R708-15 PMID 21191001 Effect of high-dose total body irradiation on ACTH, corticosterone, and catecholamines in the rat. (Cohen EP, Bruder ED, Cullinan WE, Ziegler D, Raff H) Transl Res 2011 Jan;157(1):38-47 PMID 21146149 Biomarkers: Salivary cortisol or cortisone? (Raff H, Findling JW) Nat Rev Endocrinol 2010 Dec;6(12):658-60 PMID 21102645 Growth suppression of mouse pituitary corticotroph tumor AtT20 cells by curcumin: a model for treating Cushing's disease. (Bangaru ML, Woodliff J, Raff H, Kansra S) PLoS One 2010;5(4):e9893 PMID 20405005 Cardiac and plasma lipid profiles in response to acute hypoxia in neonatal and young adult rats. (Bruder ED, Raff H) Lipids Health Dis 2010;9:3 PMID 20070908 Technical details influence the diagnostic accuracy of the 1 microg ACTH stimulation test. (Wade M, Baid S, Calis K, Raff H, Sinaii N, Nieman L) Eur J Endocrinol 2010 Jan;162(1):109-13 PMID 19797501 Utility of salivary cortisol measurements in Cushing's syndrome and adrenal insufficiency. (Raff H) J Clin Endocrinol Metab 2009 Oct;94(10):3647-55 PMID 19602555 Late-night salivary cortisol for the diagnosis of Cushing syndrome: a meta-analysis. (Carroll T, Raff H, Findling JW) Endocr Pract 2009 May-Jun;15(4):335-42 PMID 19502211 Late-Night Salivary Cortisol for the Diagnosis of Cushing's Syndrome: A Meta-Analysis. (Carroll T, Raff H, Findling JW) Endocr Pract 2009 May 6:1-17 PMID 19454388 Control of leptin with altitude exposure. (Raff H) J Appl Physiol 2008 Nov;105(5):1686-7 PMID 18984917 Cosyntropin-stimulated salivary cortisol in hospitalized patients with hypoproteinemia. (Raff H, Brock S, Findling JW) Endocrine 2008 Aug-Dec;34(1-3):68-74 PMID 18946745 Development of the ACTH and corticosterone response to acute hypoxia in the neonatal rat. (Bruder ED, Taylor JK, Kamer KJ, Raff H) Am J Physiol Regul Integr Comp Physiol 2008 Oct;295(4):R1195-203 PMID 18703410 Immulite vs Scantibodies IRMA plasma ACTH assay. (Raff H) Clin Chem 2008 Aug;54(8):1409-10 PMID 18664454 Pre-analytical issues for testosterone and estradiol assays. (Raff H, Sluss PM) Steroids 2008 Dec 12;73(13):1297-304 PMID 18589466 Late-night salivary cortisol measurement in the diagnosis of Cushing's syndrome. (Carroll T, Raff H, Findling JW) Nat Clin Pract Endocrinol Metab 2008 Jun;4(6):344-50 PMID 18446140 Epidermal growth factor and parathyroid hormone-related peptide mRNA in the mammary gland and their concentrations in milk: effects of postpartum hypoxia in lactating rats. (Bruder ED, Hoof JV, Young JB, Raff H) Horm Metab Res 2008 Jul;40(7):446-53 PMID 18401831 Using saliva to measure endogenous cortisol in nursing home residents with advanced dementia. (Woods DL, Kovach CR, Raff H, Joosse L, Basmadjian A, Hegadoren KM) Res Nurs Health 2008 Jun;31(3):283-94 PMID 18228609 Limitations of nocturnal salivary cortisol and urine free cortisol in the diagnosis of mild Cushing's syndrome. (Kidambi S, Raff H, Findling JW) Eur J Endocrinol 2007 Dec;157(6):725-31 PMID 18057379 Augmented hypothalamic corticotrophin-releasing hormone mRNA and corticosterone responses to stress in adult rats exposed to perinatal hypoxia. (Raff H, Jacobson L, Cullinan WE) J Neuroendocrinol 2007 Nov;19(11):907-12 PMID 17927669 Renal interstitial corticosterone and 11-dehydrocorticosterone in conscious rats. (Usa K, Singh RJ, Netzel BC, Liu Y, Raff H, Liang M) Am J Physiol Renal Physiol 2007 Jul;293(1):F186-92 PMID 17389675 Glucocorticoid feedback control of corticotropin in the hypoxic neonatal rat. (Raff H, Jacobson L) J Endocrinol 2007 Feb;192(2):453-8 PMID 17283245 Microarray and real-time PCR analysis of adrenal gland gene expression in the 7-day-old rat: effects of hypoxia from birth. (Bruder ED, Lee JJ, Widmaier EP, Raff H) Physiol Genomics 2007 Apr 24;29(2):193-200 PMID 17213367 Adrenal lipid profiles of chemically sympathectomized normoxic and hypoxic neonatal rats. (Bruder ED, Henderson LM, Raff H) Horm Metab Res 2006 Dec;38(12):807-11 PMID 17163355 An oxidized derivative of linoleic acid stimulates dehydroepiandrosterone production by human adrenal cells. (Bruder ED, Raff H, Goodfriend TL, Aurora St. Luke's Medical Center Adrenal Tumor Study Group) Horm Metab Res 2006 Dec;38(12):803-6 PMID 17163354 Association of adrenal steroids with hypertension and the metabolic syndrome in blacks. (Kidambi S, Kotchen JM, Grim CE, Raff H, Mao J, Singh RJ, Kotchen TA) Hypertension 2007 Mar;49(3):704-11 PMID 17159085 Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement. (Rosner W, Auchus RJ, Azziz R, Sluss PM, Raff H) J Clin Endocrinol Metab 2007 Feb;92(2):405-13 PMID 17090633 Cushing's Syndrome: important issues in diagnosis and management. (Findling JW, Raff H) J Clin Endocrinol Metab 2006 Oct;91(10):3746-53 PMID 16868050 Adiponectin and resistin in the neonatal rat: effects of dexamethasone and hypoxia. (Raff H, Bruder ED) Endocrine 2006 Apr;29(2):341-4 PMID 16785610 Comparative evaluation of a new immunoradiometric assay for corticotropin. (Wilkinson CW, Raff H) Clin Chem Lab Med 2006;44(5):669-71 PMID 16681443 Characterization of pituitary-adrenocortical activity in the Malayan flying fox (Pteropus vampyrus). (Reeder DM, Raff H, Kunz TH, Widmaier EP) J Comp Physiol B 2006 Aug;176(6):513-9 PMID 16496155 Elevated late-night salivary cortisol levels in elderly male type 2 diabetic veterans. (Liu H, Bravata DM, Cabaccan J, Raff H, Ryzen E) Clin Endocrinol (Oxf) 2005 Dec;63(6):642-9 PMID 16343098 Teaching glucocorticoid negative feedback and adrenocortical regulation using a classic paper by Dr. Dwight Ingle. (Raff H) Adv Physiol Educ 2005 Sep;29(3):141-3 PMID 16109792 Steroidogenesis in human aldosterone-secreting adenomas and adrenal hyperplasias: effects of hypoxia in vitro. (Raff H, Bruder ED, St. Luke's Medical Center Adrenal Tumor Study Group) Am J Physiol Endocrinol Metab 2006 Jan;290(1):E199-E203 PMID 16105860 Plasma leptin and ghrelin in the neonatal rat: interaction of dexamethasone and hypoxia. (Bruder ED, Jacobson L, Raff H) J Endocrinol 2005 Jun;185(3):477-84 PMID 15930174 Screening and diagnosis of Cushing's syndrome. (Findling JW, Raff H) Endocrinol Metab Clin North Am 2005 Jun;34(2):385-402, ix-x PMID 15850849 Identification of patients with Cushing's disease with negative pituitary adrenocorticotropin gradients during inferior petrosal sinus sampling: prolactin as an index of pituitary venous effluent. (Findling JW, Kehoe ME, Raff H) J Clin Endocrinol Metab 2004 Dec;89(12):6005-9 PMID 15579751 Dexamethasone treatment in the newborn rat: fatty acid profiling of lung, brain, and serum lipids. (Bruder ED, Lee PC, Raff H) J Appl Physiol 2005 Mar;98(3):981-90 PMID 15542569 The significance of the blood gas analyzer. (Raff H) J Appl Physiol 2004 Nov;97(5):1597-8 PMID 15475548 Introduction to the classic papers commemorating the APS Legacy Project. (Raff H, Benos D, Reich M) Am J Physiol Renal Physiol 2004 Nov;287(5):F859-60 PMID 15475536 Lipid and fatty acid profiles in the brain, liver, and stomach contents of neonatal rats: effects of hypoxia. (Bruder ED, Lee PC, Raff H) Am J Physiol Endocrinol Metab 2005 Feb;288(2):E314-20 PMID 15466920 Neonatal dexamethasone therapy: short- and long-term consequences. (Raff H) Trends Endocrinol Metab 2004 Oct;15(8):351-2 PMID 15380804 Metabolic consequences of hypoxia from birth and dexamethasone treatment in the neonatal rat: comprehensive hepatic lipid and fatty acid profiling. (Bruder ED, Lee PC, Raff H) Endocrinology 2004 Nov;145(11):5364-72 PMID 15271879 The low-dose dexamethasone suppression test: a reevaluation in patients with Cushing's syndrome. (Findling JW, Raff H, Aron DC) J Clin Endocrinol Metab 2004 Mar;89(3):1222-6 PMID 15001614 Metabolomic analysis of adrenal lipids during hypoxia in the neonatal rat: implications in steroidogenesis. (Bruder ED, Lee PC, Raff H) Am J Physiol Endocrinol Metab 2004 May;286(5):E697-703 PMID 14709419 A suggestion for the multiple author issue. (Raff H) Science 2003 Oct 3;302(5642):55-7 PMID 14526060 Basal and adrenocorticotropin-stimulated corticosterone in the neonatal rat exposed to hypoxia from birth: modulation by chemical sympathectomy. (Raff H, Lee JJ, Widmaier EP, Oaks MK, Engeland WC) Endocrinology 2004 Jan;145(1):79-86 PMID 14525916 Total and active ghrelin in developing rats during hypoxia. (Raff H) Endocrine 2003 Jul;21(2):159-61 PMID 12897380 Elevated corticosterone and inhibition of ACTH responses to CRH and ether in the neonatal rat: effect of hypoxia from birth. (Raff H, Jacobson L, Cullinan WE) Am J Physiol Regul Integr Comp Physiol 2003 Nov;285(5):R1224-30 PMID 12855418 A physiologic approach to diagnosis of the Cushing syndrome. (Raff H, Findling JW) Ann Intern Med 2003 Jun 17;138(12):980-91 PMID 12809455 Effects of hypoxia on the development of intestinal enzymes in neonatal and juvenile rats. (Lee PC, Struve M, Raff H) Exp Biol Med (Maywood) 2003 Jun;228(6):717-23 PMID 12773704 An oxidized metabolite of linoleic acid stimulates corticosterone production by rat adrenal cells. (Bruder ED, Ball DL, Goodfriend TL, Raff H) Am J Physiol Regul Integr Comp Physiol 2003 Jun;284(6):R1631-5 PMID 12689852 Oxidized products of linoleic acid stimulate adrenal steroidogenesis. (Goodfriend TL, Ball DL, Raff H, Bruder ED, Gardner HW, Spiteller G) Endocr Res 2002 Nov;28(4):325-30 PMID 12530633 New enzyme immunoassay for salivary cortisol. (Raff H, Homar PJ, Skoner DP) Clin Chem 2003 Jan;49(1):203-4 PMID 12507989 Adrenocortical responses to ACTH in neonatal rats: effect of hypoxia from birth on corticosterone, StAR, and PBR. (Raff H, Hong JJ, Oaks MK, Widmaier EP) Am J Physiol Regul Integr Comp Physiol 2003 Jan;284(1):R78-85 PMID 12388447 Effect of hypoxia on parathyroid hormone in lactating and neonatal rats: interaction with halothane. (Raff H) Endocrine 2002 Apr;17(3):157-60 PMID 12108514 Neonatal hypoxia in the rat: effects on exocrine pancreatic development. (Lee PC, Struve M, Lewis SM, Raff H) J Pediatr Gastroenterol Nutr 2002 May;34(5):542-7 PMID 12050582 PTHrP during petrosal sinus sampling. (Raff H, Shaker JL, Magill SB, Kehoe ME, Findling JW) Clin Endocrinol (Oxf) 2002 Mar;56(3):419 PMID 11940056 Growth hormone therapy during neonatal hypoxia in rats: body composition, bone mineral density, and insulin-like growth factor-1 expression. (Raff H, Bruder ED, Jankowski B, Oaks MK, Colman RJ) Endocrine 2001 Nov;16(2):139-43 PMID 11887935 Oxygen-dependence of ACTH-stimulated aldosterone and corticosterone synthesis in the rat adrenal cortex: developmental aspects. (Bruder ED, Nagler AK, Raff H) J Endocrinol 2002 Mar;172(3):595-604 PMID 11874708 A comparison of methods for assessing hypothalamic-pituitary-adrenal (HPA) axis activity in asthma patients treated with inhaled corticosteroids. (Nelson HS, Stricker W, Casale TB, Raff H, Fourré JA, Aron DC, Newman KB) J Clin Pharmacol 2002 Mar;42(3):319-26 PMID 11865969 Comparison of two methods for measuring salivary cortisol. (Raff H, Homar PJ, Burns EA) Clin Chem 2002 Jan;48(1):207-8 PMID 11751565 Suppression of hypothalamic-pituitary-adrenal axis activity with inhaled flunisolide and fluticasone propionate in adult asthma patients. (Casale TB, Nelson HS, Stricker WE, Raff H, Newman KB) Ann Allergy Asthma Immunol 2001 Nov;87(5):379-85 PMID 11730179 Mandibular and palatal tori, bone mineral density, and salivary cortisol in community-dwelling elderly men and women. (Hjertstedt J, Burns EA, Fleming R, Raff H, Rudman I, Duthie EH, Wilson CR) J Gerontol A Biol Sci Med Sci 2001 Nov;56(11):M731-5 PMID 11682583 Diagnosis and differential diagnosis of Cushing's syndrome. (Findling JW, Raff H) Endocrinol Metab Clin North Am 2001 Sep;30(3):729-47 PMID 11571938 Effect of neonatal hypoxia on leptin, insulin, growth hormone and body composition in the rat. (Raff H, Bruder ED, Jankowski BM, Colman RJ) Horm Metab Res 2001 Mar;33(3):151-5 PMID 11355748 Comparison of adrenal vein sampling and computed tomography in the differentiation of primary aldosteronism. (Magill SB, Raff H, Shaker JL, Brickner RC, Knechtges TE, Kehoe ME, Findling JW) J Clin Endocrinol Metab 2001 Mar;86(3):1066-71 PMID 11238487 Randomized trial of oral hydrocortisone and its effect on emergency physicians during night duty. (Whitcomb JE, Findling JW, Raff H, Harnsher K) WMJ 2000 Oct;99(7):37-41, 46 PMID 11089449 The effect of fetal hypoxia on adrenocortical function in the 7-day-old rat. (Raff H, Bruder ED, Jankowski BM, Engeland WC) Endocrine 2000 Aug;13(1):111-6 PMID 11051054 Effect of neonatal hypoxia on the development of hepatic lipase in the rat. (Lee PC, Jelinek B, Struve M, Bruder ED, Raff H) Am J Physiol Regul Integr Comp Physiol 2000 Oct;279(4):R1341-7 PMID 11004003 Neonatal hypoxic hyperlipidemia in the rat: effects on aldosterone and corticosterone synthesis in vitro. (Raff H, Bruder ED, Jankowski BM, Goodfriend TL) Am J Physiol Regul Integr Comp Physiol 2000 Mar;278(3):R663-8 PMID 10712286 The effect of hypoxia on plasma leptin and insulin in newborn and juvenile rats. (Raff H, Bruder ED, Jankowski BM) Endocrine 1999 Aug;11(1):37-9 PMID 10668639 Elevated salivary cortisol in the evening in healthy elderly men and women: correlation with bone mineral density. (Raff H, Raff JL, Duthie EH, Wilson CR, Sasse EA, Rudman I, Mattson D) J Gerontol A Biol Sci Med Sci 1999 Sep;54(9):M479-83 PMID 10536652 The effect of hypoxia from birth on the regulation of aldosterone in the 7-day-old rat: plasma hormones, steroidogenesis in vitro, and steroidogenic enzyme messenger ribonucleic acid. (Raff H, Jankowski BM, Bruder ED, Engeland WC, Oaks MK) Endocrinology 1999 Jul;140(7):3147-53 PMID 10385408 Newer diagnostic techniques and problems in Cushing's disease. (Findling JW, Raff H) Endocrinol Metab Clin North Am 1999 Mar;28(1):191-210 PMID 10207691 Late-night salivary cortisol as a screening test for Cushing's syndrome. (Raff H, Raff JL, Findling JW) J Clin Endocrinol Metab 1998 Aug;83(8):2681-6 PMID 9709931 Effectiveness versus efficacy: the limited value in clinical practice of high dose dexamethasone suppression testing in the differential diagnosis of adrenocorticotropin-dependent Cushing's syndrome. (Aron DC, Raff H, Findling JW) J Clin Endocrinol Metab 1997 Jun;82(6):1780-5 PMID 9177382 Intraoperative adrenocorticotropin levels during transsphenoidal surgery for Cushing's disease do not predict cure. (Graham KE, Samuels MH, Raff H, Barnwell SL, Cook DM) J Clin Endocrinol Metab 1997 Jun;82(6):1776-9 PMID 9177381 Effect of exposure to hypoxia from birth on aldosterone in rabbits: role of unesterified fatty acids. (Raff H, Jankowski BM, Goodfriend TL, Baker JE, Papanek PE) Am J Physiol 1997 Apr;272(4 Pt 2):R1084-7 PMID 9140005 Liddle's syndrome: prospective genetic screening and suppressed aldosterone secretion in an extended kindred. (Findling JW, Raff H, Hansson JH, Lifton RP) J Clin Endocrinol Metab 1997 Apr;82(4):1071-4 PMID 9100575 Adrenergic, respiratory, and cardiovascular effects of core cooling in humans. (Frank SM, Higgins MS, Fleisher LA, Sitzmann JV, Raff H, Breslow MJ) Am J Physiol 1997 Feb;272(2 Pt 2):R557-62 PMID 9124478 Corticosterone inhibition of osmotically stimulated vasopressin from hypothalamic-neurohypophysial explants. (Papanek PE, Sladek CD, Raff H) Am J Physiol 1997 Jan;272(1 Pt 2):R158-62 PMID 9039004 Hypoxia in vivo inhibits aldosterone synthesis and aldosterone synthase mRNA in rats. (Raff H, Jankowski BM, Engeland WC, Oaks MK) J Appl Physiol 1996 Aug;81(2):604-10 PMID 8872624 Aldosterone release from adrenal cells is inhibited by reduced oxygen levels in vitro during maturation in rabbits. (Papanek PE, Jankowski BM, Raff H) Reprod Fertil Dev 1996;8(8):1131-6 PMID 8981636 Vasopressin responses to corticotropin-releasing factor and hypertonicity after truncal vagotomy in dogs. (Raff H, Papanek PE, Cowles VE) Am J Physiol 1996 Jan;270(1 Pt 2):R94-8 PMID 8769789 Catecholamine and cortisol responses to lower extremity revascularization: correlation with outcome variables. Perioperative Ischemia Randomized Anesthesia Trial Study Group. (Parker SD, Breslow MJ, Frank SM, Rosenfeld BA, Norris EJ, Christopherson R, Rock P, Gottlieb SO, Raff H, Perler BA) Crit Care Med 1995 Dec;23(12):1954-61 PMID 7497717 Factitious Cushing's syndrome: discovery with use of a sensitive immunoradiometric assay for corticotropin. (O'Shaughnessy IM, Raff H, Findling JW) Endocr Pract 1995 Sep-Oct;1(5):327-9 PMID 15251578 Differentiation of the expression of aldosterone synthase and 11 beta-hydroxylase mRNA in the rat adrenal cortex by reverse transcriptase-polymerase chain reaction. (Oaks MK, Raff H) J Steroid Biochem Mol Biol 1995 Sep;54(5-6):193-9 PMID 7577700 Case report: renal phosphate wasting, syndrome of inappropriate antidiuretic hormone, and ectopic corticotropin production in small cell carcinoma. (Shaker JL, Brickner RC, Divgi AB, Raff H, Findling JW) Am J Med Sci 1995 Jul;310(1):38-41 PMID 7604839 O2 dependence of pregnenolone and aldosterone synthesis in mitochondria from bovine zona glomerulosa cells. (Raff H, Jankowski B) J Appl Physiol 1995 May;78(5):1625-8 PMID 7649895 Intraoperative measurement of adrenocorticotropin (ACTH) during removal of ACTH-secreting bronchial carcinoid tumors. (Raff H, Shaker JL, Seifert PE, Werner PH, Hazelrigg SR, Findling JW) J Clin Endocrinol Metab 1995 Mar;80(3):1036-9 PMID 7883819 Elevated follicular fluid angiotensin II and pregnancy outcome. (Heimler I, Rawlins RG, Binor Z, Aiman J, Raff H, Hutz RJ) Fertil Steril 1995 Mar;63(3):528-34 PMID 7851582 The catecholamine, cortisol, and hemodynamic responses to mild perioperative hypothermia. A randomized clinical trial. (Frank SM, Higgins MS, Breslow MJ, Fleisher LA, Gorman RB, Sitzmann JV, Raff H, Beattie C) Anesthesiology 1995 Jan;82(1):83-93 PMID 7832339 Chronic physiological increases in cortisol inhibit the vasopressin response to hypertonicity in conscious dogs. (Papanek PE, Raff H) Am J Physiol 1994 Nov;267(5 Pt 2):R1342-9 PMID 7977863 Longitudinal evaluation of adrenocortical function in patients infected with the human immunodeficiency virus. (Findling JW, Buggy BP, Gilson IH, Brummitt CF, Bernstein BM, Raff H) J Clin Endocrinol Metab 1994 Oct;79(4):1091-6 PMID 7962279 The effect of intracarotid vasopressin infusion on ACTH release in neurohypophysectomized, conscious dogs. (Raff H, Papanek PE, Liard JF, Cowley AW Jr) Am J Physiol 1994 Sep;267(3 Pt 2):R653-8 PMID 8092308 Epidural triamcinolone suppresses the pituitary-adrenal axis in human subjects. (Kay J, Findling JW, Raff H) Anesth Analg 1994 Sep;79(3):501-5 PMID 8067555 Rapid measurement of corticotropin (ACTH) with a modified immunochemiluminescent assay. (Raff H, Shaker JL, Nelson DK, Findling JW) Clin Chem 1994 Jul;40(7 Pt 1):1344 PMID 8013111 Physiological increases in cortisol inhibit basal vasopressin release in conscious dogs. (Papanek PE, Raff H) Am J Physiol 1994 Jun;266(6 Pt 2):R1744-51 PMID 8024023 Inhibition of aldosterone release by hypoxia in vitro: interaction with carbon monoxide. (Raff H, Jankowski B) J Appl Physiol 1994 Feb;76(2):689-93 PMID 8175579 Secretion of adrenocorticotrophin (ACTH) and ACTH precursors in ovine anterior pituitary cells: actions of corticotrophin-releasing hormone, arginine vasopressin and glucocorticoids. (Schwartz J, Ash P, Ford V, Raff H, Crosby S, White A) J Endocrinol 1994 Feb;140(2):189-95 PMID 8169554 Adrenal blood flow and secretory effects of adrenergic receptor stimulation. (Ligier B, Breslow MJ, Clarkson K, Raff H, Traystman RJ) Am J Physiol 1994 Jan;266(1 Pt 2):H220-7 PMID 7905716 Determinants of catecholamine and cortisol responses to lower extremity revascularization. The PIRAT Study Group. (Breslow MJ, Parker SD, Frank SM, Norris EJ, Yates H, Raff H, Rock P, Christopherson R, Rosenfeld BA, Beattie C) Anesthesiology 1993 Dec;79(6):1202-9 PMID 8267195 Effect of CO2/pH on the aldosterone response to hypoxia in bovine adrenal cells in vitro. (Raff H, Jankowski B) Am J Physiol 1993 Oct;265(4 Pt 2):R820-5 PMID 8238452 Interactions between neurohypophysial hormones and the ACTH-adrenocortical axis. (Raff H) Ann N Y Acad Sci 1993 Jul 22;689:411-25 PMID 8396873 Fatty acids may regulate aldosterone secretion and mediate some of insulin's effects on blood pressure. (Goodfriend TL, Ball DL, Elliott ME, Chabhi A, Duong T, Raff H, Schneider EG, Brown RD, Weinbergers MH) Prostaglandins Leukot Essent Fatty Acids 1993 Jan;48(1):43-50 PMID 8424122 Effect of age and blood pressure on the heart rate, vasopressin, and renin response to hypoxia in fetal sheep. (Raff H, Wood CE) Am J Physiol 1992 Oct;263(4 Pt 2):R880-4 PMID 1415801 Effect of hypotension and hyperosmolality on vasopressin and ACTH responses to hypoglycemia in conscious dogs. (Raff H, Papanek PE, Cowley AW Jr) Am J Physiol 1992 Aug;263(2 Pt 2):R382-8 PMID 1324617 The conversion of corticosterone to aldosterone is the site of the oxygen sensitivity of the bovine adrenal zona glomerulosa. (Brickner RC, Jankowski B, Raff H) Endocrinology 1992 Jan;130(1):88-92 PMID 1309354 Performance on multiple choice/short answer tests is not a sufficient criterion for evaluating the educational value of live animal laboratories in the teaching of physiology. (Dawson CA, Cowley AW Jr, Spurr GB, Osborn JL, Raff H, Forster HV, Harder DR, Liard JF, Lombard JH, Stekiel WJ) Am J Physiol 1991 Dec;261(6 Pt 3):S34-5 PMID 1755480 Vasopressin response to haemorrhage in rats: effect of hypoxia and water restriction. (Raff H, Rossing MH, Doepker SK, Griffen SC, Jankowski BM) Clin Exp Pharmacol Physiol 1991 Oct;18(10):725-9 PMID 1764817 Lack of coupling between adrenal cortical metabolic activity and blood flow in anesthetized dogs. (Sakima NT, Breslow MJ, Raff H, Traystman RJ) Am J Physiol 1991 Aug;261(2 Pt 2):H410-5 PMID 1652212 Routine inferior petrosal sinus sampling in the differential diagnosis of adrenocorticotropin (ACTH)-dependent Cushing's syndrome: early recognition of the occult ectopic ACTH syndrome. (Findling JW, Kehoe ME, Shaker JL, Raff H) J Clin Endocrinol Metab 1991 Aug;73(2):408-13 PMID 1649842 Influence of angiotensin II on pressure natriuresis and renal hemodynamics in volume-expanded rats. (Mattson DL, Raff H, Roman RJ) Am J Physiol 1991 Jun;260(6 Pt 2):R1200-9 PMID 2058747 Arginine vasopressin responses to hypoxia and hypercapnia in late-gestation fetal sheep. (Raff H, Kane CW, Wood CE) Am J Physiol 1991 Jun;260(6 Pt 2):R1077-81 PMID 2058735 Oxygen sensitivity of potassium- and angiotensin II-stimulated aldosterone release by bovine adrenal cells. (Brickner RC, Raff H) J Endocrinol 1991 Apr;129(1):43-8 PMID 2030327 ACTH and vasopressin responses to insulin-induced hypoglycemia in intact and neurohypophysectomized conscious dogs. (Raff H, Papanek PE, Cowley AW Jr) Neuroendocrinology 1991 Jan;53(1):85-90 PMID 1646414 Effect of adrenal hypotension on elicited secretory activity in anesthetized dogs. (Breslow MJ, Tobin JR, Kubos KL, Raff H, Traystman RJ) Am J Physiol 1991 Jan;260(1 Pt 2):H21-6 PMID 1992799 Stimulation of atrial natriuretic peptide and vasopressin during retrograde mitral valvuloplasty. (Lewin RF, Raff H, Findling JW, Dorros G) Am Heart J 1990 Dec;120(6 Pt 1):1305-10 PMID 2147351 Changes in adrenal oxygen consumption during catecholamine secretion in anesthetized dogs. (Breslow MJ, Tobin JR, Mandrell TD, Racusen LC, Raff H, Traystman RJ) Am J Physiol 1990 Sep;259(3 Pt 2):H681-8 PMID 2396681 Peripheral chemoreceptor control of fetal renin responses to hypoxia and hypercapnia. (Wood CE, Kane C, Raff H) Circ Res 1990 Sep;67(3):722-32 PMID 2118838 Aldosterone control in critically ill patients: ACTH, metoclopramide, and atrial natriuretic peptide. (Raff H, Findling JW) Crit Care Med 1990 Sep;18(9):915-20 PMID 2168306 The effect of oxygen on aldosterone release from bovine adrenocortical cells in vitro: PO2 versus steroidogenesis. (Raff H, Kohandarvish S) Endocrinology 1990 Aug;127(2):682-7 PMID 2164917 The use of immunoradiometric assay for the measurement of ACTH in human plasma. (Findling JW, Engeland WC, Raff H) Trends Endocrinol Metab 1990 Jul-Aug;1(6):283-7 PMID 18411131 Vasopressin responses to hypoxia in conscious rats: interaction with water restriction. (Griffen SC, Raff H) J Endocrinol 1990 Apr;125(1):61-6 PMID 2338532 Renin response to hemorrhage in conscious rats: effect of acute reductions in hematocrit. (Raff H) Am J Physiol 1990 Feb;258(2 Pt 2):R487-91 PMID 2178451 Cortisol inhibition of vasopressin and ACTH responses to arterial hypotension in conscious dogs. (Raff H, Skelton MM, Cowley AW Jr) Am J Physiol 1990 Jan;258(1 Pt 2):R64-9 PMID 2154137 Impact of exercise training on plasma adrenocorticotropin response to a well-learned vigilance task. (Blaney J, Sothmann M, Raff H, Hart B, Horn T) Psychoneuroendocrinology 1990;15(5-6):453-62 PMID 1966301 Adrenal blood flow and secretory relationships during hypoxia in anesthetized dogs. (Breslow MJ, Ball TD, Miller CF, Raff H, Traystman RJ) Am J Physiol 1989 Nov;257(5 Pt 2):H1458-65 PMID 2556046 Short loop adrenocorticotropin (ACTH) feedback after ACTH-(1-24) injection in man is an artifact of the immunoradiometric assay. (Raff H, Findling JW, Wong J) J Clin Endocrinol Metab 1989 Sep;69(3):678-80 PMID 2547830 Stimulation of atrial natriuretic peptide and vasopressin during percutaneous transluminal aortic valvuloplasty. (Lewin RF, Raff H, Findling JW, Skelton MM, Cowley AW Jr, King JF, Dorros G) Am Heart J 1989 Aug;118(2):292-8 PMID 2546414 Feedback control of vasopressin and corticotrophin secretion in conscious dogs: effect of hypertonic saline. (Raff H, Skelton MM, Cowley AW Jr) J Endocrinol 1989 Jul;122(1):41-8 PMID 2549155 Low oxygen selectively inhibits aldosterone secretion from bovine adrenocortical cells in vitro. (Raff H, Ball DL, Goodfriend TL) Am J Physiol 1989 May;256(5 Pt 1):E640-4 PMID 2541624 A new immunoradiometric assay for corticotropin evaluated in normal subjects and patients with Cushing's syndrome. (Raff H, Findling JW) Clin Chem 1989 Apr;35(4):596-600 PMID 2539271 Regional adrenal blood flow during hypoxia in anesthetized, ventilated dogs. (Nishijima MK, Breslow MJ, Raff H, Traystman RJ) Am J Physiol 1989 Jan;256(1 Pt 2):H94-100 PMID 2536247 Fast cortisol-induced inhibition of the adrenocorticotropin response to surgery in humans. (Raff H, Flemma RJ, Findling JW) J Clin Endocrinol Metab 1988 Dec;67(6):1146-8 PMID 2848053 Evaluation of a blood sample-transfusion protocol in rats: blood gases, renin, and ACTH. (Raff H) Am J Physiol 1988 Nov;255(5 Pt 2):R851-4 PMID 2847565 Fluid balance in acute and chronic lung disease. (Colice GL, Farber M, Rose CE Jr, Raff H, Ramirez G) Am Rev Respir Dis 1988 Oct;138(4):1052-3 PMID 2974262 Renin response to graded haemorrhage in conscious rats. (Roarty TP, Raff H) Clin Exp Pharmacol Physiol 1988 May;15(5):373-8 PMID 3078279 Control of adrenocorticotropin secretion and adrenocortical sensitivity in neurohypophysectomized conscious dogs: effects of acute and chronic vasopressin replacement. (Raff H, Merrill DC, Skelton MM, Brownfield MS, Cowley AW Jr) Endocrinology 1988 Apr;122(4):1410-8 PMID 2831029 Renin, ACTH, and aldosterone during acute hypercapnia and hypoxia in conscious rats. (Raff H, Roarty TP) Am J Physiol 1988 Mar;254(3 Pt 2):R431-5 PMID 2831742 Inhibition of the adrenocorticotropin response to surgery in humans: interaction between dexamethasone and fentanyl. (Raff H, Norton AJ, Flemma RJ, Findling JW) J Clin Endocrinol Metab 1987 Aug;65(2):295-8 PMID 3036903 Selective hypoaldosteronism due to an endogenous impairment in angiotensin II production. (Findling JW, Adams AH, Raff H) N Engl J Med 1987 Jun 25;316(26):1632-5 PMID 3035375 Glucocorticoid inhibition of neurohypophysial vasopressin secretion. (Raff H) Am J Physiol 1987 Apr;252(4 Pt 2):R635-44 PMID 3032001 Bilateral adrenal hemorrhage associated with heparin-induced thrombocytopenia. (Findling JW, Korducki JM, Lahiri PK, Miller DD, Raff H) Wis Med J 1987 Mar;86(3):27-9 PMID 3564517 The dissociation of renin and aldosterone during critical illness. (Findling JW, Waters VO, Raff H) J Clin Endocrinol Metab 1987 Mar;64(3):592-5 PMID 3029157 Vasopressin responses to corticotropin releasing factor and hyperosmolality in conscious dogs. (Raff H, Skelton MM, Merrill DC, Cowley AW Jr) Am J Physiol 1986 Dec;251(6 Pt 2):R1235-9 PMID 3024513 Aldosterone responses to ACTH during hypoxia in conscious rats. (Raff H, Chadwick KJ) Clin Exp Pharmacol Physiol 1986 Nov-Dec;13(11-12):827-30 PMID 3030587 Total peripheral resistance during cardiac tamponade: adrenergic and angiotensin roles. (Cogswell TL, Bernath GA, Raff H, Hoffmann RG, Klopfenstein HS) Am J Physiol 1986 Nov;251(5 Pt 2):R916-22 PMID 3022609 Pneumocystis carinii pneumonia complicating intermittent Cushing's syndrome. (Findling JW, Buggy BP, Segerson TP, Raff H) Wis Med J 1986 Sep;85(9):23-5 PMID 3490721 Renin-angiotensin II-aldosterone and ACTH-cortisol control during acute hypoxemia and exercise in patients with chronic obstructive pulmonary disease. (Raff H, Levy SA) Am Rev Respir Dis 1986 Mar;133(3):396-9 PMID 3006560 Renin, ACTH, and adrenocortical function during hypoxia and hemorrhage in conscious rats. (Raff H, Sandri RB, Segerson TP) Am J Physiol 1986 Feb;250(2 Pt 2):R240-4 PMID 3004236 Acute volume expansion decreases adrenocortical sensitivity to ACTH and angiotensin II. (Raff H, Shinsako J, Wade CE, Keil LC, Dallman MF) Am J Physiol 1985 Nov;249(5 Pt 2):R611-6 PMID 2998212 Renin-angiotensin-aldosterone system during acute hypoxemia. (Raff H) J Appl Physiol 1985 Sep;59(3):1026-7 PMID 3902767 Control of ACTH and vasopressin in neurohypophysectomized conscious dogs. (Raff H, Merrill D, Skelton M, Cowley AW Jr) Am J Physiol 1985 Aug;249(2 Pt 2):R281-4 PMID 2992297 Adrenocortical function after acute carbon monoxide exposure in humans. (Raff H, Goldmann RW, Kindwall EP) Arch Environ Health 1985 Mar-Apr;40(2):88-90 PMID 2988463 Rate sensitivity of blood pressure to hypoxia. (Licko V, Raff H) J Theor Biol 1985 Feb 21;112(4):839-45 PMID 3999765 Correlation of plasma angiotensin II concentration and plasma renin activity during acute hypoxia in dogs. (Raff H, Maselli J, Reid IA) Clin Exp Pharmacol Physiol 1985 Jan-Feb;12(1):91-4 PMID 2988837 Responses of in vitro rat diaphragm to changes in acid-base environment. (Fitzgerald RS, Hauer MC, Bierkamper GG, Raff H) J Appl Physiol 1984 Oct;57(4):1202-10 PMID 6438030 Renin and ACTH responses to hypercapnia and hypoxia after chronic carotid chemodenervation. (Raff H, Shinsako J, Dallman MF) Am J Physiol 1984 Sep;247(3 Pt 2):R412-7 PMID 6089593 Measurement of hormones and blood gases during hypoxia in conscious cannulated rats. (Raff H, Fagin KD) J Appl Physiol 1984 May;56(5):1426-30 PMID 6327586 Feedback inhibition of adrenocorticotropin and vasopressin responses to hypoxia by physiological increases in endogenous plasma corticosteroids in dogs. (Raff H, Shinsako J, Keil LC, Dallman MF) Endocrinology 1984 Apr;114(4):1245-9 PMID 6323137 Vasopressin, ACTH, and blood pressure during hypoxia induced at different rates. (Raff H, Shinsako J, Keil LC, Dallman MF) Am J Physiol 1983 Nov;245(5 Pt 1):E489-93 PMID 6314822 Effect of hypoxia and hypercapnia on catecholamine content in cat carotid body. (Fitzgerald RS, Garger P, Hauer MC, Raff H, Fechter L) J Appl Physiol 1983 May;54(5):1408-13 PMID 6408049 Vasopressin, ACTH, and corticosteroids during hypercapnia and graded hypoxia in dogs. (Raff H, Shinsako J, Keil LC, Dallman MF) Am J Physiol 1983 May;244(5):E453-8 PMID 6303130 Surgery potentiates adrenocortical responses to hypoxia in dogs. (Raff H, Shinsako J, Dallman MF) Proc Soc Exp Biol Med 1983 Apr;172(4):400-6 PMID 6302711 Chemoreceptor involvement in cortisol responses to hypoxia in ventilated dogs. (Raff H, Tzankoff SP, Fitzgerald RS) J Appl Physiol 1982 Apr;52(4):1092-6 PMID 7085410 ACTH and cortisol responses to hypoxia in dogs. (Raff H, Tzankoff SP, Fitzgerald RS) J Appl Physiol 1981 Nov;51(5):1257-60 PMID 6271714 Grants and Awards
Perinatal Hypoxia: Adrenocortical-Metabolic Adaptations (#9202700 01/01/2003 - 12/31/2007) Sponsor: NIH Diabetes, Digestive and Kidney Diseases