Medical College of Wisconsin
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James T. Casper MD

James T. Casper MD

Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Hematology/Oncology
Program: Oncology


Research Experience

  • Hematopoietic Stem Cell Transplantation
  • Immune System Diseases
  • Immunologic Deficiency Syndromes
  • Stem Cell Transplantation
  • Clinical Expertise

  • Autoimmunity
  • Hematopoietic Stem Cell Transplantation
  • Severe Combined Immunodeficiency
  • Transplantation Immunology
  • immunology
  • Publications

  • Autoantibody stabilization of the classical pathway C3 convertase leading to C3 deficiency and Neisserial sepsis: C4 nephritic factor revisited. (Miller EC, Chase NM, Densen P, Hintermeyer MK, Casper JT, Atkinson JP) Clin Immunol 2012 Dec;145(3):241-50 PMID 23117396
  • Use of combination chemotherapy for treatment of granulomatous and lymphocytic interstitial lung disease (GLILD) in patients with common variable immunodeficiency (CVID). (Chase NM, Verbsky JW, Hintermeyer MK, Waukau JK, Tomita-Mitchell A, Casper JT, Singh S, Shahir KS, Tisol WB, Nugent ML, Rao RN, Mackinnon AC, Goodman LR, Simpson PM, Routes JM) J Clin Immunol 2013 Jan;33(1):30-9 PMID 22930256
  • Patient-centred screening for primary immunodeficiency, a multi-stage diagnostic protocol designed for non-immunologists: 2011 update. (de Vries E, European Society for Immunodeficiencies (ESID) members) Clin Exp Immunol 2012 Jan;167(1):108-19 PMID 22132890
  • Malignancies after hematopoietic cell transplantation for primary immune deficiencies: a report from the Center for International Blood and Marrow Transplant Research. (Kamani NR, Kumar S, Hassebroek A, Eapen M, LeRademacher J, Casper J, Cowan M, Sánchez de Toledo J, Ferster A, Szabolcs P, Wingard JR, Horwitz E, Filipovich AH) Biol Blood Marrow Transplant 2011 Dec;17(12):1783-9 PMID 21658461
  • Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease. (Worthey EA, Mayer AN, Syverson GD, Helbling D, Bonacci BB, Decker B, Serpe JM, Dasu T, Tschannen MR, Veith RL, Basehore MJ, Broeckel U, Tomita-Mitchell A, Arca MJ, Casper JT, Margolis DA, Bick DP, Hessner MJ, Routes JM, Verbsky JW, Jacob HJ, Dimmock DP) Genet Med 2011 Mar;13(3):255-62 PMID 21173700
  • Recent decrease in acute graft-versus-host disease in children with leukemia receiving unrelated donor bone marrow transplants. (Davies SM, Wang D, Wang T, Arora M, Ringden O, Anasetti C, Pavletic S, Casper J, Macmillan ML, Sanders J, Wall D, Kernan NA) Biol Blood Marrow Transplant 2009 Mar;15(3):360-6 PMID 19203727
  • A scheme for defining cause of death and its application in the T cell depletion trial. (Copelan E, Casper JT, Carter SL, van Burik JA, Hurd D, Mendizabal AM, Wagner JE, Yanovich S, Kernan NA) Biol Blood Marrow Transplant 2007 Dec;13(12):1469-76 PMID 18022577
  • Alternative donor bone marrow transplant for children with Philadelphia chromosome ALL. (Talano JM, Casper JT, Camitta BM, Keever-Taylor CA, Murray KJ, Eapen M, Pierce KL, Margolis DA) Bone Marrow Transplant 2006 Jan;37(2):135-41 PMID 16273115
  • Influence of T-cell depletion on chronic graft-versus-host disease: results of a multicenter randomized trial in unrelated marrow donor transplantation. (Pavletic SZ, Carter SL, Kernan NA, Henslee-Downey J, Mendizabal AM, Papadopoulos E, Gingrich R, Casper J, Yanovich S, Weisdorf D, National Heart, Lung, and Blood Institute Unrelated Donor Marrow Transplantation Trial) Blood 2005 Nov 1;106(9):3308-13 PMID 16046530
  • Evaluation of histogenesis of B-lymphocytes in pediatric EBV-related post-transplant lymphoproliferative disorders. (Abed N, Casper JT, Camitta BM, Margolis D, Trost B, Orentas R, Chang CC) Bone Marrow Transplant 2004 Feb;33(3):321-7 PMID 14688820
  • Monitoring and modulation of Epstein-Barr virus loads in pediatric transplant patients. (Orentas RJ, Schauer DW Jr, Ellis FW, Walczak J, Casper JT, Margolis DA) Pediatr Transplant 2003 Aug;7(4):305-14 PMID 12890010
  • Cognitive and psychosocial functioning of pediatric hematopoietic stem cell transplant patients: a prospective longitudinal study. (Kupst MJ, Penati B, Debban B, Camitta B, Pietryga D, Margolis D, Murray K, Casper J) Bone Marrow Transplant 2002 Nov;30(9):609-17 PMID 12407436
  • Production of macrophage migration inhibitory factor by human and murine neuroblastoma. (Bin Q, Johnson BD, Schauer DW, Casper JT, Orentas RJ) Tumour Biol 2002 May-Jun;23(3):123-9 PMID 12218292
  • Transfusion support with RBCs from an Mk homozygote in a case of autoimmune hemolytic anemia following diphtheria-pertussis-tetanus vaccination. (Johnson ST, McFarland JG, Kelly KJ, Casper JT, Gottschall JL) Transfusion 2002 May;42(5):567-71 PMID 12084164
  • Analysis of risk factors for the development of GVHD after T cell-depleted allogeneic BMT: effect of HLA disparity, ABO incompatibility, and method of T-cell depletion. (Keever-Taylor CA, Bredeson C, Loberiza FR, Casper JT, Lawton C, Rizzo D, Burns WH, Margolis DA, Vesole DH, Horowitz M, Zhang MJ, Juckett M, Drobyski WR) Biol Blood Marrow Transplant 2001;7(11):620-30 PMID 11760150
  • Protection from lethal murine graft-versus-host disease without compromise of alloengraftment using transgenic donor T cells expressing a thymidine kinase suicide gene. (Drobyski WR, Morse HC 3rd, Burns WH, Casper JT, Sandford G) Blood 2001 Apr 15;97(8):2506-13 PMID 11290616
  • Impact of donor type on outcome of bone marrow transplantation for Wiskott-Aldrich syndrome: collaborative study of the International Bone Marrow Transplant Registry and the National Marrow Donor Program. (Filipovich AH, Stone JV, Tomany SC, Ireland M, Kollman C, Pelz CJ, Casper JT, Cowan MJ, Edwards JR, Fasth A, Gale RP, Junker A, Kamani NR, Loechelt BJ, Pietryga DW, Ringdén O, Vowels M, Hegland J, Williams AV, Klein JP, Sobocinski KA, Rowlings PA, Horowitz MM) Blood 2001 Mar 15;97(6):1598-603 PMID 11238097
  • Engraftment and survival after unrelated-donor bone marrow transplantation: a report from the national marrow donor program. (Davies SM, Kollman C, Anasetti C, Antin JH, Gajewski J, Casper JT, Nademanee A, Noreen H, King R, Confer D, Kernan NA) Blood 2000 Dec 15;96(13):4096-102 PMID 11110679
  • Infiltrating T cells during liver graft-versus-host disease show a restricted T-cell repertoire. (Margolis DA, Casper JT, Segura AD, Janczak T, McOlash L, Fisher B, Miller K, Gorski J) Biol Blood Marrow Transplant 2000;6(4):408-15 PMID 10917576
  • Alternative-donor hematopoietic stem-cell transplantation for severe aplastic anemia. (Margolis DA, Casper JT) Semin Hematol 2000 Jan;37(1):43-55 PMID 10676910
  • Treatment of relapsed leukemia after unrelated donor marrow transplantation with unrelated donor leukocyte infusions. (Porter DL, Collins RH Jr, Hardy C, Kernan NA, Drobyski WR, Giralt S, Flowers ME, Casper J, Leahey A, Parker P, Mick R, Bate-Boyle B, King R, Antin JH) Blood 2000 Feb 15;95(4):1214-21 PMID 10666193
  • Treatment of therapy-refractory B-lineage acute lymphoblastic leukemia with an apoptosis-inducing CD19-directed tyrosine kinase inhibitor. (Uckun FM, Messinger Y, Chen CL, O'Neill K, Myers DE, Goldman F, Hurvitz C, Casper JT, Levine A) Clin Cancer Res 1999 Dec;5(12):3906-13 PMID 10632319
  • Clinical pharmacokinetics of the CD19 receptor-directed tyrosine kinase inhibitor B43-Genistein in patients with B-lineage lymphoid malignancies. (Chen CL, Levine A, Rao A, O'Neill K, Messinger Y, Myers DE, Goldman F, Hurvitz C, Casper JT, Uckun FM) J Clin Pharmacol 1999 Dec;39(12):1248-55 PMID 10586390
  • Marrow transplantation from unrelated donors for patients with severe aplastic anemia who have failed immunosuppressive therapy. (Deeg HJ, Seidel K, Casper J, Anasetti C, Davies S, Gajeweski JL, Territo M, Ramsay N, Harris RE, Catro-Malaspina H, Collins R, Champlin R, Schoch G, King R, Howe C) Biol Blood Marrow Transplant 1999;5(4):243-52 PMID 10465104
  • Detection of Epstein-Barr virus EBER sequence in post-transplant lymphoma patients with DNA dendrimers. (Orentas RJ, Rospkopf SJ, Casper JT, Getts RC, Nilsen TW) J Virol Methods 1999 Feb;77(2):153-63 PMID 10092139
  • T cell-depleted allogeneic bone marrow transplantation for high-risk non-Hodgkin's lymphoma: clinical and molecular follow-up. (Juckett M, Rowlings P, Hessner M, Keever-Taylor C, Burns W, Camitta B, Casper J, Drobyski WR, Hanson G, Horowitz M, Lawton C, Margolis J, Peitryga D, Vesole D) Bone Marrow Transplant 1998 May;21(9):893-9 PMID 9613781
  • Long-term results of selective renal shielding in patients undergoing total body irradiation in preparation for bone marrow transplantation. (Lawton CA, Cohen EP, Murray KJ, Derus SW, Casper JT, Drobyski WR, Horowitz MM, Moulder JE) Bone Marrow Transplant 1997 Dec;20(12):1069-74 PMID 9466280
  • Adoptive immunotherapy for leukemia: donor lymphocytes transduced with the herpes simplex thymidine kinase gene for remission induction. HGTRI 0103. (Link CJ Jr, Burt RK, Traynor AE, Drobyski WR, Seregina T, Levy JP, Gordon L, Rosen ST, Burns WH, Camitta B, Casper J, Horowitz M, Juckett M, Lawton C, Margolis D, Pietryga D, Rowlings P, Taylor C, Furtado M, Stefka J, Gupta-Burt S, Kaiser H, Vesole DH) Hum Gene Ther 1998 Jan 1;9(1):115-34 PMID 9458247
  • Effect of T cell subset dose on outcome of T cell-depleted bone marrow transplantation. (Kawanishi Y, Passweg J, Drobyski WR, Rowlings P, Cook-Craig A, Casper J, Pietryga D, Garbrecht F, Camitta B, Horowitz M, Juckett M, Margolis D, Flomenberg N, Keever-Taylor CA) Bone Marrow Transplant 1997 Jun;19(11):1069-77 PMID 9193748
  • Results of allogeneic bone marrow transplants for leukemia using donors other than HLA-identical siblings. (Szydlo R, Goldman JM, Klein JP, Gale RP, Ash RC, Bach FH, Bradley BA, Casper JT, Flomenberg N, Gajewski JL, Gluckman E, Henslee-Downey PJ, Hows JM, Jacobsen N, Kolb HJ, Lowenberg B, Masaoka T, Rowlings PA, Sondel PM, van Bekkum DW, van Rood JJ, Vowels MR, Zhang MJ, Horowitz MM) J Clin Oncol 1997 May;15(5):1767-77 PMID 9164184
  • Association of donor-derived host-reactive cytolytic and helper T cells with outcome following alternative donor T cell-depleted bone marrow transplantation. (Keever-Taylor CA, Passweg J, Kawanishi Y, Casper J, Flomenberg N, Baxter-Lowe LA) Bone Marrow Transplant 1997 May;19(10):1001-9 PMID 9169644
  • Detection of adenovirus DNA in peripheral blood mononuclear cells by polymerase chain reaction assay. (Flomenberg P, Gutierrez E, Piaskowski V, Casper JT) J Med Virol 1997 Mar;51(3):182-8 PMID 9139081
  • Human adenovirus-specific CD8+ T-cell responses are not inhibited by E3-19K in the presence of gamma interferon. (Flomenberg P, Piaskowski V, Truitt RL, Casper JT) J Virol 1996 Sep;70(9):6314-22 PMID 8709259
  • Unrelated donor bone marrow transplantation to treat severe aplastic anaemia in children and young adults. (Margolis D, Camitta B, Pietryga D, Keever-Taylor C, Baxter-Lowe LA, Pierce K, Kupst MJ, French J 3rd, Truitt R, Lawton C, Murray K, Garbrecht F, Flomenberg N, Casper J) Br J Haematol 1996 Jul;94(1):65-72 PMID 8757510
  • Spontaneous, persistent infection of a B-cell lymphoma with adenovirus. (Flomenberg P, Piaskowski V, Harb J, Segura A, Casper JT) J Med Virol 1996 Mar;48(3):267-72 PMID 8801288
  • Use of unrelated marrow grafts compensates for reduced graft-versus-leukemia reactivity after T-cell-depleted allogeneic marrow transplantation for chronic myelogenous leukemia. (Hessner MJ, Endean DJ, Casper JT, Horowitz MM, Keever-Taylor CA, Roth M, Flomenberg N, Drobyski WR) Blood 1995 Nov 15;86(10):3987-96 PMID 7579370
  • Therapeutic plasma exchange does not appear to be effective in the management of thrombotic thrombocytopenic purpura/hemolytic uremic syndrome following bone marrow transplantation. (Sarode R, McFarland JG, Flomenberg N, Casper JT, Cohen EP, Drobyski WR, Ash RC, Horowitz MM, Camitta B, Lawton C) Bone Marrow Transplant 1995 Aug;16(2):271-5 PMID 7581147
  • Unrelated bone marrow donor transplants for children with leukemia or myelodysplasia. (Casper J, Camitta B, Truitt R, Baxter-Lowe LA, Bunin N, Lawton C, Murray K, Hunter J, Pietryga D, Garbrecht F) Blood 1995 May 1;85(9):2354-63 PMID 7727769
  • Characterization of human proliferative T cell responses to adenovirus. (Flomenberg P, Piaskowski V, Truitt RL, Casper JT) J Infect Dis 1995 May;171(5):1090-6 PMID 7751682
  • Efficacy of fluorescence in situ hybridization for detecting PML/RARA gene fusion in treated and untreated acute promyelocytic leukemia. (Schad CR, Hanson CA, Paietta E, Casper J, Jalal SM, Dewald GW) Mayo Clin Proc 1994 Nov;69(11):1047-53 PMID 7967757
  • Increasing incidence of adenovirus disease in bone marrow transplant recipients. (Flomenberg P, Babbitt J, Drobyski WR, Ash RC, Carrigan DR, Sedmak GV, McAuliffe T, Camitta B, Horowitz MM, Bunin N) J Infect Dis 1994 Apr;169(4):775-81 PMID 8133091
  • Effect of T-cell depletion as graft-versus-host disease prophylaxis on engraftment, relapse, and disease-free survival in unrelated marrow transplantation for chronic myelogenous leukemia. (Drobyski WR, Ash RC, Casper JT, McAuliffe T, Horowitz MM, Lawton C, Keever C, Baxter-Lowe LA, Camitta B, Garbrecht F) Blood 1994 Apr 1;83(7):1980-7 PMID 8142664
  • Intensive alternating drug pairs for treatment of high-risk childhood acute lymphoblastic leukemia. A Pediatric Oncology Group pilot study. (Lauer SJ, Camitta BM, Leventhal BG, Mahoney DH Jr, Shuster JJ, Adair S, Casper JT, Civin CI, Graham M, Kiefer G) Cancer 1993 May 1;71(9):2854-61 PMID 8467463
  • Intravenous immunoglobulin: use in pediatric bone marrow transplantation. (Casper JT, Sedmak G, Harris RE, Carrigan DR, Baxter-Lowe LA, Ash RC) Semin Hematol 1992 Jul;29(3 Suppl 2):100-5 PMID 1324528
  • Pancreatitis associated with bone marrow transplantation in children. (Werlin SL, Casper J, Antonson D, Calabro C) Bone Marrow Transplant 1992 Jul;10(1):65-9 PMID 1515881
  • The predictive value of HLA-DR oligotyping for MLC responses. (Baxter-Lowe LA, Eckels DD, Ash R, Casper J, Hunter JB, Gorski J) Transplantation 1992 Jun;53(6):1352-7 PMID 1534942
  • Immunological evaluation of pediatric cancer patients receiving recombinant interleukin-2 in a phase I trial. (Truitt RL, Piaskowski V, Kirchner P, McOlash L, Camitta BM, Casper JT) J Immunother (1991) 1992 May;11(4):274-85 PMID 1599913
  • Allogeneic marrow transplantation using T cell depletion for patients with juvenile chronic myelogenous leukemia without HLA-identical siblings. (Bunin NJ, Casper JT, Lawton C, Murray K, Camitta BM, Greenwood M, Geil J, Ash RC) Bone Marrow Transplant 1992 Feb;9(2):119-22 PMID 1571710
  • Late renal dysfunction in adult survivors of bone marrow transplantation. (Lawton CA, Cohen EP, Barber-Derus SW, Murray KJ, Ash RC, Casper JT, Moulder JE) Cancer 1991 Jun 1;67(11):2795-800 PMID 2025844
  • Bone marrow transplantation from related donors other than HLA-identical siblings: effect of T cell depletion. (Ash RC, Horowitz MM, Gale RP, van Bekkum DW, Casper JT, Gordon-Smith EC, Henslee PJ, Kolb HJ, Lowenberg B, Masaoka T) Bone Marrow Transplant 1991 Jun;7(6):443-52 PMID 1873591
  • Future directions in selection of donors for bone marrow transplantation: role of oligonucleotide genotyping. (Baxter-Lowe LA, Eckels DD, Ash R, Casper J, Hunter JB, Gorksi J) Transplant Proc 1991 Feb;23(1 Pt 2):1699-700 PMID 1824902
  • Kinetic analysis of human IL-2 activated cytotoxic cells. (LeFever AV, Piaskowski VD, Casper JT, Truitt RL) Immunopharmacol Immunotoxicol 1991;13(1-2):147-68 PMID 1770217
  • High-dose chemoradiotherapy supported by marrow infusions for advanced neuroblastoma: a Pediatric Oncology Group study. (Pole JG, Casper J, Elfenbein G, Gee A, Gross S, Janssen W, Koch P, Marcus R, Pick T, Shuster J) J Clin Oncol 1991 Jan;9(1):152-8 PMID 1985165
  • Ability of circular extrachromosomal DNA molecules to carry amplified MYCN proto-oncogenes in human neuroblastomas in vivo. (VanDevanter DR, Piaskowski VD, Casper JT, Douglass EC, Von Hoff DD) J Natl Cancer Inst 1990 Dec 5;82(23):1815-21 PMID 2250296
  • Preservation of lymphokine-activated killer activity following T cell depletion of human bone marrow. (Drobyski WR, Piaskowski V, Ash RC, Casper JT, Truitt RL) Transplantation 1990 Oct;50(4):625-32 PMID 1699309
  • Autoimmune thyroiditis after bone marrow transplantation. (Wyatt DT, Lum LG, Casper J, Hunter J, Camitta B) Bone Marrow Transplant 1990 May;5(5):357-61 PMID 2350629
  • Successful allogeneic transplantation of T-cell-depleted bone marrow from closely HLA-matched unrelated donors. (Ash RC, Casper JT, Chitambar CR, Hansen R, Bunin N, Truitt RL, Lawton C, Murray K, Hunter J, Baxter-Lowe LA) N Engl J Med 1990 Feb 22;322(8):485-94 PMID 2300120
  • Successful treatment with an unrelated-donor bone marrow transplant in an HLA-deficient patient with severe combined immune deficiency ("bare lymphocyte syndrome"). (Casper JT, Ash RA, Kirchner P, Hunter JB, Havens PL, Chusid MJ) J Pediatr 1990 Feb;116(2):262-5 PMID 2299498
  • Treatment of meningeal relapse in childhood acute lymphoblastic leukemia: II. A prospective study of intellectual loss specific to CNS relapse and therapy. (Longeway K, Mulhern R, Crisco J, Kun L, Lauer S, Casper J, Camitta B, Hoffman RG) Am J Pediatr Hematol Oncol 1990;12(1):45-50 PMID 2309979
  • Bone marrow transplantation for severe aplastic anemia in children. (Casper JT, Truitt RR, Baxter-Lowe LA, Ash RC) Am J Pediatr Hematol Oncol 1990;12(4):434-48 PMID 2285124
  • Bone marrow transplantation for children with severe aplastic anemia: use of donors other than HLA-identical siblings. (Camitta B, Ash R, Menitove J, Murray K, Lawton C, Hunter J, Casper J) Blood 1989 Oct;74(5):1852-7 PMID 2529004
  • Intermediate-dose intravenous methotrexate and mercaptopurine therapy for non-T, non-B acute lymphocytic leukemia of childhood: a Pediatric Oncology Group study. (Camitta B, Leventhal B, Lauer S, Shuster JJ, Adair S, Casper J, Civin C, Graham M, Mahoney D, Munoz L) J Clin Oncol 1989 Oct;7(10):1539-44 PMID 2778483
  • HLA gene amplification and hybridization analysis of polymorphism. HLA matching for bone marrow transplantation of a patient with HLA-deficient severe combined immunodeficiency syndrome. (Baxter-Lowe LA, Hunter JB, Casper JT, Gorski J) J Clin Invest 1989 Aug;84(2):613-8 PMID 2668336
  • Technical modifications in hyperfractionated total body irradiation for T-lymphocyte deplete bone marrow transplant. (Lawton CA, Barber-Derus S, Murray KJ, Casper JT, Ash RC, Gillin MT, Wilson JF) Int J Radiat Oncol Biol Phys 1989 Aug;17(2):319-22 PMID 2666364
  • Partially matched bone marrow transplantation in patients with myelodysplastic syndromes. (Bunin NJ, Casper JT, Chitambar C, Hunter J, Truitt R, Menitove J, Camitta BM, Ash R) J Clin Oncol 1988 Dec;6(12):1851-5 PMID 3058877
  • Clinical cancer: 33. Clinical applications and research advances in marrow transplantation. (Ash RC, Casper JT) Wis Med J 1988 Nov;87(11):17-21 PMID 3068916
  • Intravenous immunoglobulin may lessen all forms of infection in patients receiving allogeneic bone marrow transplantation for acute lymphoblastic leukemia: a pediatric oncology group study. (Graham-Pole J, Camitta B, Casper J, Elfenbein G, Gross S, Herzig R, Koch P, Mahoney D, Marcus R, Munoz L) Bone Marrow Transplant 1988 Nov;3(6):559-66 PMID 3063324
  • The autologous mixed lymphocyte response: isolation of mononuclear cell populations by counterflow centrifugal elutriation. (Piaskowski V, Nikaein A, Lauer S, Casper JT) J Clin Lab Immunol 1988 Jul;26(3):147-51 PMID 2976427
  • Bone marrow transplantation (BMT) for advanced neuroblastoma (NBL): a multicenter POG pilot study. (Graham-Pole J, Gee AP, Gross S, Casper J, Graham M, Harvey W, Kapoor N, Koch P, Mendenhall N, Norris D) Prog Clin Biol Res 1988;271:215-23 PMID 3043449
  • Cytosine arabinoside/cyclophosphamide pulses during continuation therapy for childhood acute lymphoblastic leukemia. Potential selective effect in T-cell leukemia. (Lauer SJ, Pinkel D, Buchanan GR, Sartain P, Cornet JM, Krance R, Borella LD, Casper JT, Kun LE, Hoffman RG) Cancer 1987 Nov 15;60(10):2366-71 PMID 3499211
  • Consistent N-myc copy number in simultaneous or consecutive neuroblastoma samples from sixty individual patients. (Brodeur GM, Hayes FA, Green AA, Casper JT, Wasson J, Wallach S, Seeger RC) Cancer Res 1987 Aug 15;47(16):4248-53 PMID 2440561
  • Expression of GD3 ganglioside in childhood T-cell lymphoblastic malignancies. (Merritt WD, Casper JT, Lauer SJ, Reaman GH) Cancer Res 1987 Mar 15;47(6):1724-30 PMID 3493067
  • Treatment of refractory acute lymphoblastic leukemia with teniposide and cytarabine. (Kamen BA, Casper J, Lauer S, Camitta BM, Holcenberg JS) Cancer Treat Rep 1986 Jul;70(7):935-6 PMID 3459577
  • Cyclic neutropenia in identical twins. (Chusid MJ, Casper JT, Camitta BM, McCreadie SR) Am J Med 1986 May;80(5):994-6 PMID 3706384
  • HTLV-III serology in hemophilia: relationship with immunologic abnormalities. (Gill JC, Menitove JE, Anderson PR, Casper JT, Devare SG, Wood C, Adair S, Casey J, Scheffel C, Montgomery RR) J Pediatr 1986 Apr;108(4):511-6 PMID 3083075
  • Cerebral toxoplasmosis in an immunocompromised host. A precise and rapid diagnosis by electron microscopy. (Tang TT, Harb JM, Dunne WM Jr, Wells RG, Meyer GA, Chusid MJ, Casper JT, Camitta BM) Am J Clin Pathol 1986 Jan;85(1):104-10 PMID 3940413
  • Isolated bilateral T-cell renal lymphoblastic lymphoma. (Camitta BM, Casper JT, Kun LE, Lauer SJ, Starshak RJ, Oechler HW) Am J Pediatr Hematol Oncol 1986;8(1):8-12 PMID 3487255
  • Effectiveness of a six-drug regimen (APO) without local irradiation for treatment of mediastinal lymphoblastic lymphoma in children. (Camitta BM, Lauer SJ, Casper JT, Kirchner PA, Kun LE, Oechler HW, Adair SE) Cancer 1985 Aug 15;56(4):738-41 PMID 3839432
  • Inherited absence of OKT4 lymphocyte antigen in a chronically transfused patient with homozygous sickle cell disease. (Gill JC, Maples J, Nikaein A, Kirchner P, Lockhart D, Snyder AJ, Montgomery RR, Casper JT) J Pediatr 1985 Aug;107(2):251-3 PMID 3874945
  • Persistence and progression of immunologic abnormalities in haemophilia. (Gill JC, Wheeler D, Menitove JE, Aster RH, Casper JT, Kirchner P, Montgomery RR) Thromb Haemost 1985 Jun 24;53(3):328-31 PMID 3931282
  • Nonrandom chromosome alterations in rhabdomyosarcoma. (Trent J, Casper J, Meltzer P, Thompson F, Fogh J) Cancer Genet Cytogenet 1985 Apr 1;16(3):189-97 PMID 3978590
  • Contribution of electron microscopy of cell cultures to the classification of three round cell sarcomas in children. (Harb JM, Piaskowski V, Casper JT) Ultrastruct Pathol 1985;8(2-3):165-76 PMID 4060257
  • Terminal transferase surveillance of remission bone marrows in childhood acute lymphoblastic leukemia: improved sensitivity with countercurrent centrifugal elutriation. (Lauer SJ, Lyman S, Kirchner PA, Gottschall JL, Camitta BM, Casper JT) J Clin Lab Immunol 1985 Jan;16(1):17-22 PMID 3856682
  • Editors have ethical responsibilities, too. (Chusid MJ, Casper JT, Camitta BM) N Engl J Med 1984 Oct 11;311(15):990-1 PMID 6472434
  • Treatment of meningeal relapse in childhood acute lymphoblastic leukemia. I. Results of craniospinal irradiation. (Kun LE, Camitta BM, Mulhern RK, Lauer SJ, Kline RW, Casper JT, Kamen BA, Kaplan BM, Barber SW) J Clin Oncol 1984 May;2(5):359-64 PMID 6587015
  • Evaluation of cerebrospinal fluid mononuclear cells obtained from children with acute lymphocytic leukemia: advantages of combining cytomorphology and terminal deoxynucleotidyl transferase. (Casper JT, Lauer SJ, Kirchner PA, Gottschall JL, Camitta BM) Am J Clin Pathol 1983 Nov;80(5):666-70 PMID 6579834
  • In vitro enhancement of peripheral blood mononuclear cell natural killer activity following short term incubation with fetal calf serum. (Lauer SJ, Finlan J, Borella LD, Piaskowski VD, Casper JT) J Clin Lab Immunol 1983 Oct;12(2):105-10 PMID 6606047
  • Distinguishing characteristics of a new neuroblastoma cell line. (Casper JT, Trent JM, Harb J, Piaskowski V, Helmsworth M, Finlan J, Von Hoff DD) Cancer Genet Cytogenet 1983 Oct;10(2):177-86 PMID 6616438
  • Image correlation. Budd-Chiari Syndrome. (Sty JR, Starshak RJ, Casper JT) Clin Nucl Med 1983 Aug;8(8):369-70 PMID 6627806
  • Prospective clinical trial of a human tumor cloning system. (Von Hoff DD, Clark GM, Stogdill BJ, Sarosdy MF, O'Brien MT, Casper JT, Mattox DE, Page CP, Cruz AB, Sandbach JF) Cancer Res 1983 Apr;43(4):1926-31 PMID 6339044
  • T-lymphocyte subpopulations in patients with classic hemophilia treated with cryoprecipitate and lyophilized concentrates. (Menitove JE, Aster RH, Casper JT, Lauer SJ, Gottschall JL, Williams JE, Gill JC, Wheeler DV, Piaskowski V, Kirchner P, Montgomery RR) N Engl J Med 1983 Jan 13;308(2):83-6 PMID 6401196
  • Extraosseous accumulation of Tc-99m MDP. Metastatic intracranial neuroblastoma. (Sty JR, Starshak RJ, Casper JT) Clin Nucl Med 1983 Jan;8(1):26-7 PMID 6219852
  • Association between HLA-D region antigens and disease-free survival in childhood non-T, non-B acute lymphocytic leukemia. (Casper JT, Marrari M, Piaskowski V, Lauer SJ, Duquesnoy RJ) Blood 1982 Sep;60(3):698-702 PMID 6954996
  • Ultrastructural analysis of colonies growing in a human tumor cloning system. (Harris GJ, Zeagler J, Hodach A, Casper J, Harb J, Von Hoff DD) Cancer 1982 Aug 15;50(4):722-6 PMID 7093906
  • Bone marrow and extramedullary variations of cell membrane antigen expression in childhood lymphoid neoplasias at relapse. (Lauer S, Piaskowski V, Camitta B, Casper J) Leuk Res 1982;6(6):769-74 PMID 6961270
  • Fractionated total body irradiation for metastatic neuroblastoma. (Kun LE, Casper JT, Kline RW, Piaskowski VD) Int J Radiat Oncol Biol Phys 1981 Nov;7(11):1599-602 PMID 7037701
  • Clinical evaluation of sequentially scheduled cisplatin and VM26 in neuroblastoma: response and toxicity. (Hayes FA, Green AA, Casper J, Cornet J, Evans WE) Cancer 1981 Oct 15;48(8):1715-8 PMID 7197189
  • Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapy. (Von Hoff DD, Casper J, Bradley E, Sandbach J, Jones D, Makuch R) Am J Med 1981 May;70(5):1027-41 PMID 7234870
  • Neutropenia in dysgammaglobulinemia I: remission with immunoglobulin therapy. (Chusid MJ, Casper JT, Adair SE, Camitta BM) Wis Med J 1981 Mar;80(3):32-3 PMID 7281709
  • Bone scintigraphy: retroperitoneal fibrosis. (Sty JR, Casper JT, Oechler HW) Wis Med J 1980 Oct;79(10):27-8 PMID 7456487
  • Direct cloning of human neuroblastoma cells in soft agar culture. (Von Hoff DD, Casper J, Bradley E, Trent JM, Hodach A, Reichert C, Makuch R, Altman A) Cancer Res 1980 Oct;40(10):3591-7 PMID 7002289
  • Bone scintigraphy in neuroblastoma with ovarian metastasis. (Sty JR, Kun LE, Casper JT) Wis Med J 1980 Sep;79(9):28-9 PMID 7424045
  • Transient appearance of HLA-DRw-positive leukocytes in peripheral blood after cessation of antileukemia therapy. (Casper JT, Duquesnoy RJ, Borella L) Transplant Proc 1980 Mar;12(1):130-3 PMID 6154351
  • Failure of early intensive chemotherapy to improve prognosis in childhood acute lymphocytic leukemia. (Camitta BM, Pinkel D, Thatcher LG, Casper J, Kun LE, Lauer S) Med Pediatr Oncol 1980;8(4):383-9 PMID 7005645
  • Cloning of human neuroblastoma cells in soft agar. (Casper JT, Trent JM, Von Hoff DD) Prog Clin Biol Res 1980;48:101-11 PMID 7208513
  • Extraosseous uptake of 99mtechnetium methylene diphosphonate: neuroblastoma or radiation therapy. (Sty JR, Kun L, Casper J, Babbitt DP) Pediatr Radiol 1980;9(1):53-4 PMID 7352114
  • Shifts in expression of cell membrane phenotypes in childhood lymphoid malignancies at relapse. (Borella L, Casper JT, Lauer SJ) Blood 1979 Jul;54(1):64-71 PMID 286608
  • Immunodiagnosis of childhood ALL: problems associated with the use of peripheral blood alone. (Lauer SJ, Casper JT, Borella LD) Med Pediatr Oncol 1979;6(2):157-62 PMID 313504
  • 99mTc-methylene diphosphonate imaging in neural crest tumors. (Sty JR, Babbitt DP, Casper JT, Boedecker RA) Clin Nucl Med 1979 Jan;4(1):12-7 PMID 421393
  • Interstitial nephritis due to phenytoin hypersensitivity. (Sheth KJ, Casper JT, Good TA) J Pediatr 1977 Sep;91(3):438-41 PMID 894414
  • Reactivity of human brain antiserum with neuroblastoma cells and nonreactivity with thymocytes and lymphoblasts. (Casper JT, Borella L, Sen L) Cancer Res 1977 Jun;37(6):1750-6 PMID 66986
  • Computerized evaluation of electroencephalographic changes accompanying exchange transfusion in Reye's syndrome. (Barr RE, Ackmann JJ, Harrington GJ, Varma RR, Lewis JD, Casper JT) Electroencephalogr Clin Neurophysiol 1977 Apr;42(4):466-79 PMID 66130
  • Acute lymphoblastic leukemia (ALL) antigens detected with antisera to E rosette-froming and non-E rosette-forming ALL blasts. (Borella L, Sen L, Casper JT) J Immunol 1977 Jan;118(1):309-15 PMID 318669
  • Cell differentiation antigens versus tumor-related antigens in childhood acute lymphoblastic leukemia (ALL). Clinical significance of leukemia markers. (Borella L, Sen L, Dow LW, Casper JT) Haematol Blood Transfus 1977;20:77-85 PMID 305404
  • Exchange transfusion in Reye's syndrome with saline-washed red blood cells. (Casper JT, Varma RR, Lewis JD, Harrington GJ, Aster RH) Transfusion 1976 Mar-Apr;16(2):130-4 PMID 1258113
  • A new method for studying splenic reticuloendothelial dysfunction in sickle cell disease patients and its clinical application: a brief report. (Casper JT, Koethe S, Rodey GE, Thatcher LG) Blood 1976 Feb;47(2):183-8 PMID 1244917
  • Alternative complement pathway activity in sera from patients with sickle cell disease. (Koethe SM, Casper JT, Rodey GE) Clin Exp Immunol 1976 Jan;23(1):56-60 PMID 816581
  • Reye syndrome. A correlated electron-microscopic, viral, and biochemical observation. (Tang TT, Siegesmund KA, Sedmak GV, Casper JT, Varma RR, McCreadie SR) JAMA 1975 Jun 30;232(13):1339-46 PMID 1173398
  • Exchange transfusion for Reye's syndrome. (Lewis JD, Varma RR, Harrington G, Casper J, Ackmann JJ, Darin JC) J Surg Res 1975 Mar;18(3):327-9 PMID 1134093
  • Grants and Awards

  • A Multi-Center Pilot Study of Reduced Intensity Allogeneic Hematopoietic Stem Cell Transportation with In-Vivo T-Cell Depletion to Evaluate the Role of NK Cells and KIR Mis-Matches in Relapsed or Refractory High-Risk Neuroblastoma (#9304632 08/03/2009 - 06/30/2014) Sponsor: Nationwide Children's Hospital