Medical College of Wisconsin
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Judy R. Kersten MD

Professor

Institution: Medical College of Wisconsin
Department: Anesthesiology
Division: Clinical
Program: Operating Room Service


Leadership Positions

  • Editorial Board Member: Anesthesia & Analgesia (1999-2002), American Journal of Physiology Heart and Circulatory Physiology (1999-2005), Anesthesiology (Associate Editor, 2003-2004), Anesthesiology (Editor, 2004-present)
    Editorial Consultant: Anesthesiology, American Journal of Cardiology, Cardiovascular Research, Circulation, Free Radical Biology and Medicine, Journal of Pharmacology and Experimental Therapeutics, Journal of Molecular and Cellular Cardiology, European Journal of Physiology, Life Sciences, Microvascular Research
    Expert Analyst: Cardiovascular and Thoracic Anesthesia Journal Club (1996-1998)
    Referee, Jewish Hospital Foundation Medical Research Grant Program (1997-1998)
    Referee, The Welcome Trust Research Grant Program (1998)
    Member, American Heart Association, National Study Section on Anesthesiology, Radiology and Surgery (2000)
    Member, National Institutes of Health, Special Emphasis Panel on “Cellular and Molecular Mechanisms of Diabetic Cardiomyopathy”, June 2000
    Member, National Institutes of Health, Cardiovascular and Renal Study Section (2001-2003)
    Member, National Institutes of Health, Special Emphasis Panel December 7, 2005
    Member, National Institutes of Health, Special Emphasis Panel July 26, 2006
    Member, National Institutes of Health, Special Emphasis Panel March 23, 2007
    Member, National Institutes of Health, Myocardial Ischemia and Metabolism Study Section (2004-2005)
    Chair, National Institutes of Health, Myocardial Ischemia and Metabolism Study Section (2004-2005)
    Member, American Society of Anesthesiologists Subcommittee on Clinical Circulation (2000-2003)
    Member, Program Committee, Society of Cardiovascular Anesthesiologists Annual Meeting (2003-2005)
    Member, Foundation for Anesthesia Education and Research, Academy of Anesthesia Mentors (2004-present)
    Editor, American Board of Anesthesiology In-Training Examination (2000-2005)
    Abstract Grader, American Society of Anesthesiologists Annual Meeting (2001-2003)
    Member, American Heart Association/American College of Cardiology Committee to Update the Guidelines on Perioperative Cardiovascular Evaluation for Non-Cardiac Surgery (2005-present)
    Member, Association of University Anesthesiologists Scientific Advisory Board (2006-present)
    Abstract Grader, Association of University Anesthesiologists Annual Meeting (2006-present)
    Adjunct Member, American Society of Anesthesiologists Committee on Research (2007-2008)
    Member, Scientific Review Panel for Foundation of Anesthesia Education and Research, Mentored Research Grants (2008)
  • Publications

  • Man overboard! Rescuing myocardium with membrane rafts. (Lohr N, Kersten JR) Anesthesiology 2010 May;112(5):1076-8 PMID 20418686
  • Hyperglycemia adversely modulates endothelial nitric oxide synthase during anesthetic preconditioning through tetrahydrobiopterin- and heat shock protein 90-mediated mechanisms. (Amour J, Brzezinska AK, Jager Z, Sullivan C, Weihrauch D, Du J, Vladic N, Shi Y, Warltier DC, Pratt PF Jr, Kersten JR) Anesthesiology 2010 Mar;112(3):576-85 PMID 20124983
  • Isoflurane postconditioning protects against reperfusion injury by preventing mitochondrial permeability transition by an endothelial nitric oxide synthase-dependent mechanism. (Ge ZD, Pravdic D, Bienengraeber M, Pratt PF Jr, Auchampach JA, Gross GJ, Kersten JR, Warltier DC) Anesthesiology 2010 Jan;112(1):73-85 PMID 19996950
  • 2009 ACCF/AHA focused update on perioperative beta blockade. (American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine, Society for Vascular Surgery, Fleischmann KE, Beckman JA, Buller CE, Calkins H, Fleisher LA, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Robb JF, Valentine RJ) J Am Coll Cardiol 2009 Nov 24;54(22):2102-28 PMID 19926021
  • 2009 ACCF/AHA focused update on perioperative beta blockade incorporated into the ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery. (American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine, Society for Vascular Surgery, Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF) J Am Coll Cardiol 2009 Nov 24;54(22):e13-e118 PMID 19926002
  • 2009 ACCF/AHA focused update on perioperative beta blockade: a report of the American college of cardiology foundation/American heart association task force on practice guidelines. (Fleischmann KE, Beckman JA, Buller CE, Calkins H, Fleisher LA, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Robb JF, Valentine RJ) Circulation 2009 Nov 24;120(21):2123-51 PMID 19884474
  • 2009 ACCF/AHA focused update on perioperative beta blockade incorporated into the ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American college of cardiology foundation/American heart association task force on practice guidelines. (Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF) Circulation 2009 Nov 24;120(21):e169-276 PMID 19884473
  • Anesthesia for noncardiac surgery in adults with congenital heart disease. (Cannesson M, Earing MG, Collange V, Kersten JR) Anesthesiology 2009 Aug;111(2):432-40 PMID 19602959
  • Continuous perioperative insulin infusion decreases major cardiovascular events in patients undergoing vascular surgery: a prospective, randomized trial. (Subramaniam B, Panzica PJ, Novack V, Mahmood F, Matyal R, Mitchell JD, Sundar E, Bose R, Pomposelli F, Kersten JR, Talmor DS) Anesthesiology 2009 May;110(5):970-7 PMID 19387173
  • Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning. (Amour J, Brzezinska AK, Weihrauch D, Billstrom AR, Zielonka J, Krolikowski JG, Bienengraeber MW, Warltier DC, Pratt PF Jr, Kersten JR) Anesthesiology 2009 Feb;110(2):317-25 PMID 19194158
  • 2008 in review: advancing medicine in anesthesiology. (Eisenach JC, Borgeat A, Bosnjak ZJ, Brennan TJ, Kersten JR, Kochs E, Lerman J, Warner DS, Wiener-Kronish JP) Anesthesiology 2008 Dec;109(6):962-72 PMID 19034092
  • Preconditioning, anesthetics, and perioperative medication. (Shim YH, Kersten JR) Best Pract Res Clin Anaesthesiol 2008 Mar;22(1):151-65 PMID 18494394
  • Simvastatin restores ischemic preconditioning in the presence of hyperglycemia through a nitric oxide-mediated mechanism. (Gu W, Kehl F, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2008 Apr;108(4):634-42 PMID 18362595
  • Diabetic cardiomyopathy and anesthesia: bench to bedside. (Amour J, Kersten JR) Anesthesiology 2008 Mar;108(3):524-30 PMID 18292689
  • ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). (American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery), American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society for Vascular Surgery, Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW) Anesth Analg 2008 Mar;106(3):685-712 PMID 18292406
  • 2007 in review: a dozen steps forward in Anesthesiology. (Eisenach JC, Borgeat A, Bosnjak ZJ, Brennan TJ, Kersten JR, Kochs EF, Wiener-Kronish JP) Anesthesiology 2008 Jan;108(1):149-55 PMID 18156893
  • Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection. (Jamnicki-Abegg M, Weihrauch D, Chiari PC, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) J Cardiovasc Pharmacol 2007 Dec;50(6):670-6 PMID 18091584
  • ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery) Developed in Collaboration With the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. (Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW) J Am Coll Cardiol 2007 Oct 23;50(17):1707-32 PMID 17950159
  • ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery) developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. (Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW, American College of Cardiology, American Heart Association Task Force on Practice Guidelines (writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery), American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society for Vascular Surgery) J Am Coll Cardiol 2007 Oct 23;50(17):e159-241 PMID 17950140
  • ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. (Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Tarkington LG, Yancy CW, American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery), American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society for Vascular Surgery) Circulation 2007 Oct 23;116(17):e418-99 PMID 17901357
  • ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): Developed in Collaboration With the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. (Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, ACC/AHA TASK FORCE MEMBERS, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Buller CE, Creager MA, Ettinger SM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW) Circulation 2007 Oct 23;116(17):1971-96 PMID 17901356
  • Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo. (Pagel PS, Krolikowski JG, Shim YH, Venkatapuram S, Kersten JR, Weihrauch D, Warltier DC, Pratt PF Jr) Anesth Analg 2007 Sep;105(3):562-9 PMID 17717207
  • Drug-eluting coronary stents: what are the risks? (Kersten JR, Fleisher LA) Anesthesiology 2007 May;106(5):898-900 PMID 17457119
  • An unusual right atrial structure in a patient with a new diastolic murmur. (Iqbal Z, Gandhi SD, Kersten JR, Pagel PS) J Cardiothorac Vasc Anesth 2007 Feb;21(1):152-4 PMID 17289501
  • ACC/AHA 2006 guideline update on perioperative cardiovascular evaluation for noncardiac surgery: focused update on perioperative beta-blocker therapy--a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). (Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof EL, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, American College of Cardiology, American Heart Association Task Force on Practice Guidelines, Writing Committee to Update the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology) Anesth Analg 2007 Jan;104(1):15-26 PMID 17179239
  • Statins: The next advance in cardioprotection? (Kersten JR, Fleisher LA) Anesthesiology 2006 Dec;105(6):1079-80 PMID 17122569
  • Inhibition of apoptotic protein p53 lowers the threshold of isoflurane-induced cardioprotection during early reperfusion in rabbits. (Venkatapuram S, Wang C, Krolikowski JG, Weihrauch D, Kersten JR, Warltier DC, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Dec;103(6):1400-5 PMID 17122210
  • Ischemic preconditioning, myocardial stunning and anesthesia. (Toller WG, Kersten JR, Pagel PS, Warltier DC) Curr Opin Anaesthesiol 2000 Feb;13(1):35-40 PMID 17016277
  • Extracellular signal-regulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in rats. (Wang C, Weihrauch D, Schwabe DA, Bienengraeber M, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Aug;103(2):281-8, table of contents PMID 16861403
  • Gender-specificity of delayed preconditioning by isoflurane in rabbits: potential role of endothelial nitric oxide synthase. (Wang C, Chiari PC, Weihrauch D, Krolikowski JG, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Aug;103(2):274-80, table of contents PMID 16861402
  • Cardioprotection by volatile anesthetics: new applications for old drugs? (Pratt PF Jr, Wang C, Weihrauch D, Bienengraeber MW, Kersten JR, Pagel PS, Warltier DC) Curr Opin Anaesthesiol 2006 Aug;19(4):397-403 PMID 16829721
  • Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling. (LaDisa JF Jr, Olson LE, Douglas HA, Warltier DC, Kersten JR, Pagel PS) Biomed Eng Online 2006;5:40 PMID 16780592
  • ACC/AHA 2006 guideline update on perioperative cardiovascular evaluation for noncardiac surgery: focused update on perioperative beta-blocker therapy: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society for Vascular Medicine and Biology. (Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Page RL, Riegel B, American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Committee to Update the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology) Circulation 2006 Jun 6;113(22):2662-74 PMID 16754815
  • ACC/AHA 2006 guideline update on perioperative cardiovascular evaluation for noncardiac surgery: focused update on perioperative beta-blocker therapy: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery) developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society for Vascular Medicine and Biology. (American College of Cardiology, American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery), American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Riegel B, Robb JF, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Faxon DP, Fuster V, Halperin JL, Hiratzka LF, Hunt SA, Lytle BW, Nishimura R, Page RL, Riegel B) J Am Coll Cardiol 2006 Jun 6;47(11):2343-55 PMID 16750714
  • The influence of B-cell lymphoma 2 protein, an antiapoptotic regulator of mitochondrial permeability transition, on isoflurane-induced and ischemic postconditioning in rabbits. (Wang C, Neff DA, Krolikowski JG, Weihrauch D, Bienengraeber M, Warltier DC, Kersten JR, Pagel PS) Anesth Analg 2006 May;102(5):1355-60 PMID 16632808
  • Inhibition of glycogen synthase kinase enhances isoflurane-induced protection against myocardial infarction during early reperfusion in vivo. (Pagel PS, Krolikowski JG, Neff DA, Weihrauch D, Bienengraeber M, Kersten JR, Warltier DC) Anesth Analg 2006 May;102(5):1348-54 PMID 16632807
  • Role of Erk1/2, p70s6K, and eNOS in isoflurane-induced cardioprotection during early reperfusion in vivo. (Krolikowski JG, Weihrauch D, Bienengraeber M, Kersten JR, Warltier DC, Pagel PS) Can J Anaesth 2006 Feb;53(2):174-82 PMID 16434759
  • Inhibition of mitochondrial permeability transition enhances isoflurane-induced cardioprotection during early reperfusion: the role of mitochondrial KATP channels. (Krolikowski JG, Bienengraeber M, Weihrauch D, Warltier DC, Kersten JR, Pagel PS) Anesth Analg 2005 Dec;101(6):1590-6 PMID 16301224
  • Axial stent strut angle influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics models of stent foreshortening. (LaDisa JF Jr, Olson LE, Hettrick DA, Warltier DC, Kersten JR, Pagel PS) Biomed Eng Online 2005;4:59 PMID 16250918
  • Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression. (Jamnicki-Abegg M, Weihrauch D, Pagel PS, Kersten JR, Bosnjak ZJ, Warltier DC, Bienengraeber MW) Anesthesiology 2005 Nov;103(5):1006-14 PMID 16249675
  • Aggressive control of intraoperative blood glucose concentration: a shifting paradigm? (Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2005 Oct;103(4):677-8 PMID 16192757
  • Morphine enhances isoflurane-induced postconditioning against myocardial infarction: the role of phosphatidylinositol-3-kinase and opioid receptors in rabbits. (Weihrauch D, Krolikowski JG, Bienengraeber M, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2005 Oct;101(4):942-9, table of contents PMID 16192500
  • Role of endothelial nitric oxide synthase as a trigger and mediator of isoflurane-induced delayed preconditioning in rabbit myocardium. (Chiari PC, Bienengraeber MW, Weihrauch D, Krolikowski JG, Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2005 Jul;103(1):74-83 PMID 15983459
  • Cardioprotection by volatile anesthetics. (Bienengraeber MW, Weihrauch D, Kersten JR, Pagel PS, Warltier DC) Vascul Pharmacol 2005 Apr-May;42(5-6):243-52 PMID 15922257
  • Microfocal X-ray computed tomography post-processing operations for optimizing reconstruction volumes of stented arteries during 3D computational fluid dynamics modeling. (Ladisa JF Jr, Olson LE, Ropella KM, Molthen RC, Haworth ST, Kersten JR, Warltier DC, Pagel PS) Comput Methods Programs Biomed 2005 Aug;79(2):121-34 PMID 15894401
  • Antegrade iliac artery stent implantation for the temporal and spatial examination of stent-induced neointimal hyperplasia and alterations in regional fluid dynamics. (LaDisa JF Jr, Meier HT, Olson LE, Kersten JR, Warltier DC, Pagel PS) J Pharmacol Toxicol Methods 2005 Mar-Apr;51(2):115-21 PMID 15767204
  • Alterations in wall shear stress predict sites of neointimal hyperplasia after stent implantation in rabbit iliac arteries. (LaDisa JF Jr, Olson LE, Molthen RC, Hettrick DA, Pratt PF, Hardel MD, Kersten JR, Warltier DC, Pagel PS) Am J Physiol Heart Circ Physiol 2005 May;288(5):H2465-75 PMID 15653759
  • Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: evidence for anesthetic-induced postconditioning in rabbits. (Chiari PC, Bienengraeber MW, Pagel PS, Krolikowski JG, Kersten JR, Warltier DC) Anesthesiology 2005 Jan;102(1):102-9 PMID 15618793
  • Circumferential vascular deformation after stent implantation alters wall shear stress evaluated with time-dependent 3D computational fluid dynamics models. (LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2005 Mar;98(3):947-57 PMID 15531564
  • Intravenous emulsified halogenated anesthetics produce acute and delayed preconditioning against myocardial infarction in rabbits. (Chiari PC, Pagel PS, Tanaka K, Krolikowski JG, Ludwig LM, Trillo RA Jr, Puri N, Kersten JR, Warltier DC) Anesthesiology 2004 Nov;101(5):1160-6 PMID 15505452
  • Preconditioning by isoflurane is mediated by reactive oxygen species generated from mitochondrial electron transport chain complex III. (Ludwig LM, Tanaka K, Eells JT, Weihrauch D, Pagel PS, Kersten JR, Warltier DC) Anesth Analg 2004 Nov;99(5):1308-15; table of contents PMID 15502022
  • Chronic hyperglycemia attenuates coronary collateral development and impairs proliferative properties of myocardial interstitial fluid by production of angiostatin. (Weihrauch D, Lohr NL, Mraovic B, Ludwig LM, Chilian WM, Pagel PS, Warltier DC, Kersten JR) Circulation 2004 May 18;109(19):2343-8 PMID 15136506
  • Mechanisms of cardioprotection by volatile anesthetics. (Tanaka K, Ludwig LM, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):707-21 PMID 15108989
  • Isoflurane produces delayed preconditioning against myocardial ischemia and reperfusion injury: role of cyclooxygenase-2. (Tanaka K, Ludwig LM, Krolikowski JG, Alcindor D, Pratt PF, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):525-31 PMID 15108964
  • Protein kinase C translocation and Src protein tyrosine kinase activation mediate isoflurane-induced preconditioning in vivo: potential downstream targets of mitochondrial adenosine triphosphate-sensitive potassium channels and reactive oxygen species. (Ludwig LM, Weihrauch D, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):532-9 PMID 15108965
  • Cyclooxygenase-2 mediates ischemic, anesthetic, and pharmacologic preconditioning in vivo. (Alcindor D, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2004 Mar;100(3):547-54 PMID 15108967
  • Cardioprotection by glucose-insulin-potassium: dependence on KATP channel opening and blood glucose concentration before ischemia. (LaDisa JF Jr, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H601-7 PMID 15044191
  • Mechanisms of myocardial protection produced by chronic ethanol consumption. (Pagel PS, Kersten JR, Warltier DC) Pathophysiology 2004 Apr;10(2):121-9 PMID 15006418
  • Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery. (LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Audi SH, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2004 Jul;97(1):424-30; discussion 416 PMID 14766776
  • Influence of isoflurane on left atrial function in dogs with pacing-induced cardiomyopathy: evaluation with pressure-volume relationships. (Kehl F, Ladisa JF Jr, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2003 Dec;17(6):709-14 PMID 14689410
  • An automated coronary artery occlusion device for stimulating collateral development in vivo. (Rys R, LaDisa JF Jr, Tessmer JP, Gu W, Kersten JR, Warltier DC, Pagel PS) J Pharmacol Toxicol Methods 2002 Sep-Oct;48(2):111-8 PMID 14565568
  • Three-dimensional computational fluid dynamics modeling of alterations in coronary wall shear stress produced by stent implantation. (LaDisa JF Jr, Guler I, Olson LE, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Ann Biomed Eng 2003 Sep;31(8):972-80 PMID 12918912
  • Reactive oxygen species are critical mediators of coronary collateral development in a canine model. (Gu W, Weihrauch D, Tanaka K, Tessmer JP, Pagel PS, Kersten JR, Chilian WM, Warltier DC) Am J Physiol Heart Circ Physiol 2003 Oct;285(4):H1582-9 PMID 12816750
  • N-acetylcysteine restores isoflurane-induced preconditioning against myocardial infarction during hyperglycemia. (Kehl F, Krolikowski JG, Weihrauch D, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2003 Jun;98(6):1384-90 PMID 12766647
  • Atrial pacing lead location alters the hemodynamic effects of atrial-ventricular delay in dogs with pacing induced cardiomyopathy. (Hettrick DA, Mittelstadt JR, Kehl F, Kress TT, Tessmer JP, Krolikowski JG, Kersten JR, Warltier DC, Pagel PS) Pacing Clin Electrophysiol 2003 Apr;26(4 Pt 1):853-61 PMID 12715846
  • Adenosine type 1 (A1) receptors mediate protection against myocardial infarction produced by chronic, intermittent ingestion of ethanol in dogs. (Kehl F, Krolikowski JG, LaDisa JF Jr, Kersten JR, Warltier DC, Pagel PS) Int J Cardiol 2003 Apr;88(2-3):175-82 PMID 12714196
  • Mechanical function of the left atrium: new insights based on analysis of pressure-volume relations and Doppler echocardiography. (Pagel PS, Kehl F, Gare M, Hettrick DA, Kersten JR, Warltier DC) Anesthesiology 2003 Apr;98(4):975-94 PMID 12657862
  • Mitochondrial adenosine triphosphate-regulated potassium channel opening acts as a trigger for isoflurane-induced preconditioning by generating reactive oxygen species. (Tanaka K, Weihrauch D, Ludwig LM, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2003 Apr;98(4):935-43 PMID 12657856
  • Modifying cardiovascular risk in diabetes mellitus. (Gu W, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2003 Mar;98(3):774-9 PMID 12606925
  • Morphine enhances pharmacological preconditioning by isoflurane: role of mitochondrial K(ATP) channels and opioid receptors. (Ludwig LM, Patel HH, Gross GJ, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2003 Mar;98(3):705-11 PMID 12606915
  • Reactive oxygen species modulate coronary wall shear stress and endothelial function during hyperglycemia. (Gross ER, LaDisa JF Jr, Weihrauch D, Olson LE, Kress TT, Hettrick DA, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2003 May;284(5):H1552-9 PMID 12543642
  • Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. (Tanaka K, Weihrauch D, Kehl F, Ludwig LM, LaDisa JF Jr, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2002 Dec;97(6):1485-90 PMID 12459675
  • An intramyocardial catheter for repeated in vivo sampling of interstitial fluid. (Tessmer JP, Pagel PS, Weihrauch D, Ludwig LM, Chilian WM, Kersten JR, Warltier DC) J Pharmacol Toxicol Methods 2002 Mar-Apr;47(2):73-8 PMID 12459145
  • Isoflurane does not produce a second window of preconditioning against myocardial infarction in vivo. (Kehl F, Pagel PS, Krolikowski JG, Gu W, Toller W, Warltier DC, Kersten JR) Anesth Analg 2002 Nov;95(5):1162-8, table of contents PMID 12401584
  • Stent implantation alters coronary artery hemodynamics and wall shear stress during maximal vasodilation. (LaDisa JF Jr, Hettrick DA, Olson LE, Guler I, Gross ER, Kress TT, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2002 Dec;93(6):1939-46 PMID 12391052
  • Increases in coronary collateral blood flow produced by sevoflurane are mediated by calcium-activated potassium (BKCa) channels in vivo. (Kehl F, Krolikowski JG, Tessmer JP, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2002 Sep;97(3):725-31 PMID 12218541
  • Editorial view: anesthetic preconditioning: serendipity and science. (Warltier DC, Kersten JR, Pagel PS, Gross GJ) Anesthesiology 2002 Jul;97(1):1-3 PMID 12131096
  • Propofol alters left atrial function evaluated with pressure-volume relations in vivo. (Kehl F, Kress TT, Mraovic B, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2002 Jun;94(6):1421-6, table of contents PMID 12031999
  • Reactive oxygen species contribute to contractile dysfunction following rapid ventricular pacing in dogs. (Gare M, Mraovic B, Kehl F, Kersten JR, Warltier DC, Pagel PS) Int J Cardiol 2002 May;83(2):125-31 PMID 12007684
  • Isoflurane-induced preconditioning is attenuated by diabetes. (Tanaka K, Kehl F, Gu W, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2002 Jun;282(6):H2018-23 PMID 12003806
  • The role of mitochondrial and sarcolemmal K(ATP) channels in canine ethanol-induced preconditioning in vivo. (Pagel PS, Krolikowski JG, Kehl F, Mraovic B, Kersten JR, Warltier DC) Anesth Analg 2002 Apr;94(4):841-8, table of contents PMID 11916782
  • Is isoflurane-induced preconditioning dose related? (Kehl F, Krolikowski JG, Mraovic B, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2002 Mar;96(3):675-80 PMID 11873044
  • Hyperglycemia prevents isoflurane-induced preconditioning against myocardial infarction. (Kehl F, Krolikowski JG, Mraovic B, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2002 Jan;96(1):183-8 PMID 11753019
  • Hyperglycemia reduces coronary collateral blood flow through a nitric oxide-mediated mechanism. (Kersten JR, Toller WG, Tessmer JP, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2001 Nov;281(5):H2097-104 PMID 11668071
  • Desflurane, sevoflurane, and isoflurane affect left atrial active and passive mechanical properties and impair left atrial-left ventricular coupling in vivo: analysis using pressure-volume relations. (Gare M, Schwabe DA, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2001 Sep;95(3):689-98 PMID 11575543
  • Conscious sedation with midazolam or propofol does not alter left ventricular diastolic performance in patients with preexisting diastolic dysfunction: a transmitral and tissue Doppler transthoracic echocardiography study. (Gare M, Parail A, Milosavljevic D, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2001 Oct;93(4):865-71 PMID 11574347
  • Hyperglycemia: an independent predictor of cardiovascular risk. (Kersten JR, Pagel PS, Warltier D) J Cardiothorac Vasc Anesth 2001 Jun;15(3):404-6 PMID 11426382
  • Diabetes and hyperglycemia impair activation of mitochondrial K(ATP) channels. (Kersten JR, Montgomery MW, Ghassemi T, Gross ER, Toller WG, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2001 Apr;280(4):H1744-50 PMID 11247788
  • Ethanol enhances the functional recovery of stunned myocardium independent of K(ATP) channels in dogs. (Gross ER, Gare M, Toller WG, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2001 Feb;92(2):299-305 PMID 11159220
  • K(ATP) channels mediate the beneficial effects of chronic ethanol ingestion. (Pagel PS, Toller WG, Gross ER, Gare M, Kersten JR, Warltier DC) Am J Physiol Heart Circ Physiol 2000 Nov;279(5):H2574-9 PMID 11045996
  • Sarcolemmal and mitochondrial adenosine triphosphate- dependent potassium channels: mechanism of desflurane-induced cardioprotection. (Toller WG, Gross ER, Kersten JR, Pagel PS, Gross GJ, Warltier DC) Anesthesiology 2000 Jun;92(6):1731-9 PMID 10839925
  • Isoflurane preconditions myocardium against infarction via activation of inhibitory guanine nucleotide binding proteins. (Toller WG, Kersten JR, Gross ER, Pagel PS, Warltier DC) Anesthesiology 2000 May;92(5):1400-7 PMID 10781287
  • Correlation of esophageal conductance measurements with aortic and left ventricular diameters and stroke volume. (Hettrick DA, Battocletti JH, Pagel PS, Vurek GG, Tessmer JP, Kersten JR, Warltier DC) IEEE Trans Biomed Eng 2000 Apr;47(4):559-64 PMID 10763303
  • Diabetes abolishes ischemic preconditioning: role of glucose, insulin, and osmolality. (Kersten JR, Toller WG, Gross ER, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2000 Apr;278(4):H1218-24 PMID 10749717
  • Approaches to the prevention of perioperative myocardial ischemia. (Warltier DC, Pagel PS, Kersten JR) Anesthesiology 2000 Jan;92(1):253-9 PMID 10638923
  • Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels. (Kersten JR, Montgomery MW, Pagel PS, Warltier DC) Anesth Analg 2000 Jan;90(1):5-11 PMID 10624967
  • Mechanisms of postischemic contractile dysfunction. (Gross GJ, Kersten JR, Warltier DC) Ann Thorac Surg 1999 Nov;68(5):1898-904 PMID 10585101
  • Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs. (Toller WG, Kersten JR, Pagel PS, Hettrick DA, Warltier DC) Anesthesiology 1999 Nov;91(5):1437-46 PMID 10551596
  • Multifactorial basis for coronary collateralization: a complex adaptive response to ischemia. (Kersten JR, Pagel PS, Chilian WM, Warltier DC) Cardiovasc Res 1999 Jul;43(1):44-57 PMID 10536689
  • Isoflurane-enhanced recovery of canine stunned myocardium: role for protein kinase C? (Toller WG, Montgomery MW, Pagel PS, Hettrick DA, Warltier DC, Kersten JR) Anesthesiology 1999 Sep;91(3):713-22 PMID 10485783
  • Modulation of the adaptive response to myocardial ischemia by coexisting disease. (Kersten JR, Warltier DC) Am J Physiol 1999 Jun;276(6 Pt 2):H2268-70 PMID 10362711
  • Changes in passive but not active mechanical properties predict recovery of function of stunned myocardium. (Schmeling TJ, Hettrick DA, Kersten JR, Pagel PS, Warltier DC) Ann Biomed Eng 1999 Mar-Apr;27(2):131-40 PMID 10199689
  • Sevoflurane selectively increases coronary collateral blood flow independent of KATP channels in vivo. (Kersten JR, Schmeling T, Tessmer J, Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1999 Jan;90(1):246-56 PMID 9915334
  • RSR13, a synthetic allosteric modifier of hemoglobin, enhances recovery of stunned myocardium in dogs. (Pagel PS, Hettrick DA, Montgomery MW, Kersten JR, Warltier DC) Adv Exp Med Biol 1998;454:527-31 PMID 9889932
  • Ischemia-induced coronary collateral angiogenesis. (Weihrauch D, Tessmer JP, Kersten JR, Pagel PS, Hettrick DA, Chilian WM, Warltier DC) Adv Exp Med Biol 1998;454:281-6 PMID 9889902
  • Cardiovascular effects of xenon in isoflurane-anesthetized dogs with dilated cardiomyopathy. (Hettrick DA, Pagel PS, Kersten JR, Tessmer JP, Bosnjak ZJ, Georgieff M, Warltier DC) Anesthesiology 1998 Nov;89(5):1166-73 PMID 9822005
  • Propofol, but not thiopentone or etomidate, enhances isoflurane-induced coronary vasodilatation in dogs. (Pagel PS, Hettrick DA, Kersten JR, Lowe D, Warltier DC) Can J Anaesth 1998 Aug;45(8):809-17 PMID 9793674
  • Dexmedetomidine produces similar alterations in the determinants of left ventricular afterload in conscious dogs before and after the development of pacing-induced cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Warltier DC) Anesthesiology 1998 Sep;89(3):741-8 PMID 9743413
  • Interpretation of nonpulsatile arterial pressure-flow relations during cardiopulmonary bypass. (Hettrick DA, Kersten JR, Pagel PS, Warltier DC) Anesth Analg 1998 Sep;87(3):743 PMID 9728869
  • A novel alpha 2-adrenoceptor antagonist attenuates the early, but preserves the late cardiovascular effects of intravenous dexmedetomidine in conscious dogs. (Pagel PS, Proctor LT, Devcic A, Hettrick DA, Kersten JR, Tessmer JP, Farber NE, Schmeling WT, Warltier DC) J Cardiothorac Vasc Anesth 1998 Aug;12(4):429-34 PMID 9713732
  • Acute hyperglycemia abolishes ischemic preconditioning in vivo. (Kersten JR, Schmeling TJ, Orth KG, Pagel PS, Warltier DC) Am J Physiol 1998 Aug;275(2 Pt 2):H721-5 PMID 9683464
  • Cardiovascular effects of verapamil enantiomer combinations in conscious dogs. (Pagel PS, Hettrick DA, Lowe D, Gowrie PW, Kersten JR, Bosnjak ZJ, Warltier DC) Eur J Pharmacol 1998 May 8;348(2-3):213-21 PMID 9652336
  • Etomidate adversely alters determinants of left ventricular afterload in dogs with dilated cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Tessmer JP, Lowe D, Warltier DC) Anesth Analg 1998 May;86(5):932-8 PMID 9585271
  • RSR13, a synthetic modifier of hemoglobin-oxygen affinity, enhances the recovery of stunned myocardium in anesthetized dogs. (Pagel PS, Hettrick DA, Montgomery MW, Kersten JR, Steffen RP, Warltier DC) J Pharmacol Exp Ther 1998 Apr;285(1):1-8 PMID 9535987
  • Activation of adenosine triphosphate-regulated potassium channels: mediation of cellular and organ protection. (Kersten JR, Gross GJ, Pagel PS, Warltier DC) Anesthesiology 1998 Feb;88(2):495-513 PMID 9477071
  • Cardiovascular effects of propofol in dogs with dilated cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Lowe D, Warltier DC) Anesthesiology 1998 Jan;88(1):180-9 PMID 9447871
  • Isoflurane and halothane do not alter the enhanced afterload sensitivity of left ventricular relaxation in dogs with pacing-induced cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Tessmer JP, Lowe D, Warltier DC) Anesthesiology 1997 Oct;87(4):952-62 PMID 9357899
  • The effects of isoflurane and halothane on left ventricular afterload in dogs with dilated cardiomyopathy. (Hettrick DA, Pagel PS, Kersten JR, Lowe D, Warltier DC) Anesth Analg 1997 Nov;85(5):979-86 PMID 9356087
  • Isoflurane mimics ischemic preconditioning via activation of K(ATP) channels: reduction of myocardial infarct size with an acute memory phase. (Kersten JR, Schmeling TJ, Pagel PS, Gross GJ, Warltier DC) Anesthesiology 1997 Aug;87(2):361-70 PMID 9286901
  • Positive inotropic and lusitropic effects of triiodothyronine in conscious dogs with pacing-induced cardiomyopathy. (Jamall IN, Pagel PS, Hettrick DA, Lowe D, Kersten JR, Tessmer JP, Warltier DC) Anesthesiology 1997 Jul;87(1):102-9 PMID 9232140
  • Intracoronary levosimendan enhances contractile function of stunned myocardium. (Jamali IN, Kersten JR, Pagel PS, Hettrick DA, Warltier DC) Anesth Analg 1997 Jul;85(1):23-9 PMID 9212117
  • Temporal dependence of coronary collateral development. (Kersten JR, McGough MF, Pagel PS, Tessmer JP, Warltier DC) Cardiovasc Res 1997 May;34(2):306-12 PMID 9205544
  • Role of adenosine in isoflurane-induced cardioprotection. (Kersten JR, Orth KG, Pagel PS, Mei DA, Gross GJ, Warltier DC) Anesthesiology 1997 May;86(5):1128-39 PMID 9158363
  • Effects of levosimendan on left ventricular function: correlation with plasma concentrations in conscious dogs. (McGough MF, Pagel PS, Lowe D, Hettrick DA, Kersten JR, Warltier DC) J Cardiothorac Vasc Anesth 1997 Feb;11(1):49-53 PMID 9058220
  • Mechanism of myocardial protection by isoflurane. Role of adenosine triphosphate-regulated potassium (KATP) channels. (Kersten JR, Schmeling TJ, Hettrick DA, Pagel PS, Gross GJ, Warltier DC) Anesthesiology 1996 Oct;85(4):794-807; discussion 27A PMID 8873550
  • Isoflurane, but not halothane, improves indices of diastolic performance in dogs with rapid ventricular, pacing-induced cardiomyopathy. (Pagel PS, Lowe D, Hettrick DA, Jamali IN, Kersten JR, Tessmer JP, Warltier DC) Anesthesiology 1996 Sep;85(3):644-54 PMID 8853096
  • Glyburide, a KATP channel antagonist, attenuates the cardioprotective effects of isoflurane in stunned myocardium. (Kersten JR, Lowe D, Hettrick DA, Pagel PS, Gross GJ, Warltier DC) Anesth Analg 1996 Jul;83(1):27-33 PMID 8659760
  • Differential hemodynamic effects of the nitric oxide donor pirsidomine in comparison to SIN-1, nitroprusside and nitroglycerin. (Arkonac BM, Kersten JR, Wynsen JC, Nijhawan N, Warltier DC) Pharmacology 1996 Feb;52(2):92-100 PMID 8851630
  • Bronchospasm during pneumoperitoneum. (Kersten JR, Kane K, Coon R) Anesth Analg 1995 Nov;81(5):1099-101 PMID 7486057
  • Modulation of coronary collateral angiogenesis: a canine model of neovascularization induced by chronic ischemia. (Kersten JR, Warltier DC) J Card Surg 1995 Jul;10(4 Pt 1):354-7 PMID 7549194
  • Impaired microvascular response to graded coronary occlusion in diabetic and hyperglycemic dogs. (Kersten JR, Brooks LA, Dellsperger KC) Am J Physiol 1995 Apr;268(4 Pt 2):H1667-74 PMID 7733369
  • Protamine inhibits coronary collateral development in a canine model of repetitive coronary occlusion. (Kersten JR, Pagel PS, Warltier DC) Am J Physiol 1995 Feb;268(2 Pt 2):H720-8 PMID 7532374
  • Dexmedetomidine partially attenuates the sympathetically mediated systemic and coronary hemodynamic effects of cocaine. (Kersten JR, Pagel PS, Hettrick DA, Warltier DC) Anesth Analg 1995 Jan;80(1):114-21 PMID 7802267
  • Perfusion of ischemic myocardium during anesthesia with sevoflurane. (Kersten JR, Brayer AP, Pagel PS, Tessmer JP, Warltier DC) Anesthesiology 1994 Oct;81(4):995-1004 PMID 7943851
  • Direct negative inotropic and lusitropic effects of sevoflurane. (Harkin CP, Pagel PS, Kersten JR, Hettrick DA, Warltier DC) Anesthesiology 1994 Jul;81(1):156-67 PMID 8042785
  • Volatile anesthetics and coronary collateral circulation. (Kersten JR, Hartman JC, Pagel PS, Warltier DC) Adv Pharmacol 1994;31:269-84 PMID 7873418
  • Grants and Awards

  • Mechansims of Myocardial Ischemic Injury in Diabetes (#9204031 03/15/2006 - 02/28/2012) Sponsor: NIH Heart Lung and Blood Institute
  • Supplement: Mechansims of Myocardial Ischemic Injury in Diabetes (#9205727 06/01/2009 - 10/31/2010) Sponsor: NIH Heart Lung and Blood Institute
  • Anesthesiology Reserach Training Program (#9206367 07/01/2010 - 06/30/2015) Sponsor: NIH General Medical Sciences
  • Novel Strategies in Advancing Cardiopulmonary Resuscitation: MicroRNAs, Small Molecules with Great Potential (#9208678 07/01/2014 - 06/30/2015) Sponsor: Society of Cardiovascular Anesthesiologists Founda
  • Mechanisms of Myocardial Ischemic Injury in Diabetes (#9201917 01/01/2001 - 12/31/2005) Sponsor: NIH Heart Lung and Blood Institute
  • Anesthetic-Induced Cardiac Preconditioning (#9205281 08/01/2008 - 07/31/2014) PI of Project III: Diabetes and Anesthetic Preconditioning (#2207654)