Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Marcio H. Malogolowkin MD

Marcio H. Malogolowkin MD

Chief, Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Hematology/Oncology
Program: Oncology


Research Experience

  • Liver Neoplasms
  • Neoplasms, Germ Cell and Embryonal
  • Rhabdomyosarcoma
  • Wilms Tumor
  • Other Rare Tumors
  • Clinical Expertise

  • Liver Neoplasms
  • Neoplasms, Germ Cell and Embryonal
  • Rhabdomyosarcoma
  • Wilms Tumor
  • Rare Tumors
  • Publications

  • Surveillance after initial surgery for pediatric and adolescent girls with stage I ovarian germ cell tumors: report from the Children's Oncology Group. (Billmire DF, Cullen JW, Rescorla FJ, Davis M, Schlatter MG, Olson TA, Malogolowkin MH, Pashankar F, Villaluna D, Krailo M, Egler RA, Rodriguez-Galindo C, Frazier AL) J Clin Oncol 2014 Feb 10;32(5):465-70 PMID 24395845
  • Hepatoblastoma state of the art: pathology, genetics, risk stratification, and chemotherapy. (Czauderna P, Lopez-Terrada D, Hiyama E, Häberle B, Malogolowkin MH, Meyers RL) Curr Opin Pediatr 2014 Feb;26(1):19-28 PMID 24322718
  • Treatment of multiply relapsed wilms tumor with vincristine, irinotecan, temozolomide and bevacizumab. (Venkatramani R, Malogolowkin MH, Mascarenhas L) Pediatr Blood Cancer 2014 Apr;61(4):756-9 PMID 24115645
  • Outcome of patients with Stage II/favorable histology Wilms tumor with and without local tumor spill: a report from the National Wilms Tumor Study Group. (Green DM, Breslow NE, D'Angio GJ, Malogolowkin MH, Ritchey ML, Evans AE, Beckwith JB, Perlman EJ, Shamberger RC, Peterson S, Grundy PE, Dome JS, Thomas PR, Kalapurakal JA) Pediatr Blood Cancer 2014 Jan;61(1):134-9 PMID 24038736
  • Towards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposium. (López-Terrada D, Alaggio R, de Dávila MT, Czauderna P, Hiyama E, Katzenstein H, Leuschner I, Malogolowkin M, Meyers R, Ranganathan S, Tanaka Y, Tomlinson G, Fabrè M, Zimmermann A, Finegold MJ) Mod Pathol 2014 Mar;27(3):472-91 PMID 24008558
  • Parental tobacco and alcohol use and risk of hepatoblastoma in offspring: a report from the children's oncology group. (Johnson KJ, Williams KS, Ross JA, Krailo MD, Tomlinson GE, Malogolowkin MH, Feusner JH, Spector LG) Cancer Epidemiol Biomarkers Prev 2013 Oct;22(10):1837-43 PMID 23950215
  • A phase I study of vincristine, irinotecan, temozolomide and bevacizumab (vitb) in pediatric patients with relapsed solid tumors. (Venkatramani R, Malogolowkin M, Davidson TB, May W, Sposto R, Mascarenhas L) PLoS One 2013;8(7):e68416 PMID 23894304
  • Outcomes for patients with congenital hepatoblastoma. (Trobaugh-Lotrario AD, Chaiyachati BH, Meyers RL, Häberle B, Tomlinson GE, Katzenstein HM, Malogolowkin MH, von Schweinitz D, Krailo M, Feusner JH) Pediatr Blood Cancer 2013 Nov;60(11):1817-25 PMID 23798361
  • Incidence and outcomes of patients with late recurrence of Wilms' tumor. (Malogolowkin M, Spreafico F, Dome JS, van Tinteren H, Pritchard-Jones K, van den Heuvel-Eibrink MM, Bergeron C, de Kraker J, Graf N, COG Renal Tumors Committee and the SIOP Renal Tumor Study Group) Pediatr Blood Cancer 2013 Oct;60(10):1612-5 PMID 23737480
  • Pilot study of cisplatin, etoposide, bleomycin, and escalating dose cyclophosphamide therapy for children with high risk germ cell tumors: a report of the children's oncology group (COG). (Malogolowkin MH, Krailo M, Marina N, Olson T, Frazier AL) Pediatr Blood Cancer 2013 Oct;60(10):1602-5 PMID 23703725
  • A phase I study of oxaliplatin and doxorubicin in pediatric patients with relapsed or refractory extracranial non-hematopoietic solid tumors. (Mascarenhas L, Malogolowkin M, Armenian SH, Sposto R, Venkatramani R) Pediatr Blood Cancer 2013 Jul;60(7):1103-7 PMID 23335436
  • Children's Oncology Group's 2013 blueprint for research: renal tumors. (Dome JS, Fernandez CV, Mullen EA, Kalapurakal JA, Geller JI, Huff V, Gratias EJ, Dix DB, Ehrlich PF, Khanna G, Malogolowkin MH, Anderson JR, Naranjo A, Perlman EJ, COG Renal Tumors Committee) Pediatr Blood Cancer 2013 Jun;60(6):994-1000 PMID 23255438
  • Children's Oncology Group's 2013 blueprint for research: rare tumors. (Rodriguez-Galindo C, Krailo M, Frazier L, Chintagumpala M, Amatruda J, Katzenstein H, Malogolowkin M, Spector L, Pashankar F, Meyers R, Tomlinson G, COG Rare Tumors Disease Committee) Pediatr Blood Cancer 2013 Jun;60(6):1016-21 PMID 23255219
  • An international strategy to determine the role of high dose therapy in recurrent Wilms' tumour. (Ha TC, Spreafico F, Graf N, Dallorso S, Dome JS, Malogolowkin M, Furtwängler R, Hale JP, Moroz V, Machin D, Pritchard-Jones K) Eur J Cancer 2013 Jan;49(1):194-210 PMID 22959164
  • Current and future management strategies for relapsed or progressive hepatoblastoma. (Venkatramani R, Furman WL, Fuchs J, Warmann SW, Malogolowkin MH) Paediatr Drugs 2012 Aug 1;14(4):221-32 PMID 22702740
  • Hepatoblastoma clinical research: lessons learned and future challenges. (Perilongo G, Malogolowkin M, Feusner J) Pediatr Blood Cancer 2012 Nov;59(5):818-21 PMID 22678761
  • Pleuropulmonary blastoma: a single-institution experience. (Venkatramani R, Malogolowkin MH, Wang L, Mascarenhas L) J Pediatr Hematol Oncol 2012 Jul;34(5):e182-5 PMID 22584785
  • Treatment of Relapsed Wilms Tumor Patients (Spreafico F, Malogolowkin MH) Oncopedia
  • Parental infertility, infertility treatment and hepatoblastoma: a report from the Children's Oncology Group. (Puumala SE, Ross JA, Feusner JH, Tomlinson GE, Malogolowkin MH, Krailo MD, Spector LG) Hum Reprod 2012 Jun;27(6):1649-56 PMID 22473396
  • The depiction of brown adipose tissue is related to disease status in pediatric patients with lymphoma. (Gilsanz V, Hu HH, Smith ML, Goodarzian F, Carcich SL, Warburton NM, Malogolowkin M) AJR Am J Roentgenol 2012 Apr;198(4):909-13 PMID 22451560
  • Treatment of hepatoblastoma: the North American cooperative group experience. (Malogolowkin MH, Katzenstein HM, Krailo M, Meyers RL) Front Biosci (Elite Ed) 2012;4:1717-23 PMID 22201987
  • Tumor necrosis predicts survival following neo-adjuvant chemotherapy for hepatoblastoma. (Venkatramani R, Wang L, Malvar J, Dias D, Sposto R, Malogolowkin MH, Mascarenhas L) Pediatr Blood Cancer 2012 Sep;59(3):493-8 PMID 22190448
  • Complete surgical resection is curative for children with hepatoblastoma with pure fetal histology: a report from the Children's Oncology Group. (Malogolowkin MH, Katzenstein HM, Meyers RL, Krailo MD, Rowland JM, Haas J, Finegold MJ) J Clin Oncol 2011 Aug 20;29(24):3301-6 PMID 21768450
  • Critical review of controversial issues in the management of advanced pediatric liver tumors. (Gupta AA, Gerstle JT, Ng V, Wong A, Fecteau A, Malogolowkin MH, Meyers RL, Grant D, Grant RM) Pediatr Blood Cancer 2011 Jul 1;56(7):1013-8 PMID 21488153
  • Gorham's disease and diffuse lymphangiomatosis in children and adolescents. (Venkatramani R, Ma NS, Pitukcheewanont P, Malogolowkin MH, Mascarenhas L) Pediatr Blood Cancer 2010 Dec 22: PMID 21181877
  • Critical review of controversial issues in the management of advanced pediatric liver tumors. (Gupta AA, Gerstle JT, Ng V, Wong A, Fecteau A, Malogolowkin MH, Meyers RL, Grant D, Grant RM) Pediatr Blood Cancer 2010 Dec 1: PMID 21125617
  • A phase II trial and pharmacokinetic study of oxaliplatin in children with refractory solid tumors: a Children's Oncology Group study. (Beaty O 3rd, Berg S, Blaney S, Malogolowkin M, Krailo M, Knight R, Schaiquevich P, Stewart C, Chen Z, Nelson M, Voss S, Ivy SP, Adamson PC) Pediatr Blood Cancer 2010 Sep;55(3):440-5 PMID 20658614
  • Long-term outcomes for infants with very low risk Wilms tumor treated with surgery alone in National Wilms Tumor Study-5. (Shamberger RC, Anderson JR, Breslow NE, Perlman EJ, Beckwith JB, Ritchey ML, Haase GM, Donaldson M, Grundy PE, Weetman R, Coppes MJ, Malogolowkin M, Shearer PD, Kletzel M, Thomas PR, Macklis R, Huff V, Weeks DA, Green DM) Ann Surg 2010 Mar;251(3):555-8 PMID 20142733
  • Treatment of relapsed Wilms tumors: lessons learned. (Spreafico F, Pritchard Jones K, Malogolowkin MH, Bergeron C, Hale J, de Kraker J, Dallorso S, Acha T, de Camargo B, Dome JS, Graf N) Expert Rev Anticancer Ther 2009 Dec;9(12):1807-15 PMID 19954292
  • Amifostine does not prevent platinum-induced hearing loss associated with the treatment of children with hepatoblastoma: a report of the Intergroup Hepatoblastoma Study P9645 as a part of the Children's Oncology Group. (Katzenstein HM, Chang KW, Krailo M, Chen Z, Finegold MJ, Rowland J, Reynolds M, Pappo A, London WB, Malogolowkin M, Children's Oncology Group) Cancer 2009 Dec 15;115(24):5828-35 PMID 19813275
  • Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor. (Chen TT, Rakheja D, Hung JY, Hornsby PJ, Tabaczewski P, Malogolowkin M, Feusner J, Miskevich F, Schultz R, Tomlinson GE) Pediatr Blood Cancer 2009 Dec;53(6):1040-7 PMID 19637320
  • Predictive power of pretreatment prognostic factors in children with hepatoblastoma: a report from the Children's Oncology Group. (Meyers RL, Rowland JR, Krailo M, Chen Z, Katzenstein HM, Malogolowkin MH) Pediatr Blood Cancer 2009 Dec;53(6):1016-22 PMID 19588519
  • Redefining the role of doxorubicin for the treatment of children with hepatoblastoma. (Malogolowkin MH, Katzenstein HM, Krailo M, Chen Z, Quinn JJ, Reynolds M, Ortega JA) J Clin Oncol 2008 May 10;26(14):2379-83 PMID 18467729
  • Surgical resection of pulmonary metastatic lesions in children with hepatoblastoma. (Meyers RL, Katzenstein HM, Krailo M, McGahren ED 3rd, Malogolowkin MH) J Pediatr Surg 2007 Dec;42(12):2050-6 PMID 18082706
  • The addition of ifosfamide/etoposide to cisplatin/teniposide improves the survival of children with retinoblastoma and orbital involvement. (Antoneli CB, Ribeiro KB, Rodriguez-Galindo C, Soares FA, Arias VA, Novaes PE, Chojniak MM, Malogolowkin M) J Pediatr Hematol Oncol 2007 Oct;29(10):700-4 PMID 17921851
  • Extracranial malignant rhabdoid tumors in childhood: the Childrens Hospital Los Angeles experience. (Madigan CE, Armenian SH, Malogolowkin MH, Mascarenhas L) Cancer 2007 Nov 1;110(9):2061-6 PMID 17828773
  • Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group. (Malogolowkin M, Cotton CA, Green DM, Breslow NE, Perlman E, Miser J, Ritchey ML, Thomas PR, Grundy PE, D'Angio GJ, Beckwith JB, Shamberger RC, Haase GM, Donaldson M, Weetman R, Coppes MJ, Shearer P, Coccia P, Kletzel M, Macklis R, Tomlinson G, Huff V, Newbury R, Weeks D, National Wilms Tumor Study Group) Pediatr Blood Cancer 2008 Feb;50(2):236-41 PMID 17539021
  • Predictive value of staging systems in hepatoblastoma. (Meyers RL, Katzenstein HM, Malogolowkin MH) J Clin Oncol 2007 Feb 20;25(6):737; author reply 737-8 PMID 17308285
  • Treatment of retinoblastoma patients with chemoreduction plus local therapy: experience of the AC Camargo Hospital, Brazil. (Antoneli CB, Ribeiro KC, Steinhorst F, Novaes PE, Chojniak MM, Malogolowkin M) J Pediatr Hematol Oncol 2006 Jun;28(6):342-5 PMID 16794500
  • Intensified platinum therapy is an ineffective strategy for improving outcome in pediatric patients with advanced hepatoblastoma. (Malogolowkin MH, Katzenstein H, Krailo MD, Chen Z, Bowman L, Reynolds M, Finegold M, Greffe B, Rowland J, Newman K, Womer RB, London WB, Castleberry RP) J Clin Oncol 2006 Jun 20;24(18):2879-84 PMID 16782927
  • Prognostic factors in children with extragonadal malignant germ cell tumors: a pediatric intergroup study. (Marina N, London WB, Frazier AL, Lauer S, Rescorla F, Cushing B, Malogolowkin MH, Castleberry RP, Womer RB, Olson T) J Clin Oncol 2006 Jun 1;24(16):2544-8 PMID 16735707
  • Treatment of anaplastic histology Wilms' tumor: results from the fifth National Wilms' Tumor Study. (Dome JS, Cotton CA, Perlman EJ, Breslow NE, Kalapurakal JA, Ritchey ML, Grundy PE, Malogolowkin M, Beckwith JB, Shamberger RC, Haase GM, Coppes MJ, Coccia P, Kletzel M, Weetman RM, Donaldson M, Macklis RM, Green DM) J Clin Oncol 2006 May 20;24(15):2352-8 PMID 16710034
  • Treatment of Wilms tumor relapsing after initial treatment with vincristine and actinomycin D: a report from the National Wilms Tumor Study Group. (Green DM, Cotton CA, Malogolowkin M, Breslow NE, Perlman E, Miser J, Ritchey ML, Thomas PR, Grundy PE, D'Angio GJ, Beckwith JB, Shamberger RC, Haase GM, Donaldson M, Weetman R, Coppes MJ, Shearer P, Coccia P, Kletzel M, Macklis R, Tomlinson G, Huff V, Newbury R, Weeks D) Pediatr Blood Cancer 2007 May;48(5):493-9 PMID 16547940
  • Treatment of infantile choriocarcinoma of the liver. (Yoon JM, Burns RC, Malogolowkin MH, Mascarenhas L) Pediatr Blood Cancer 2007 Jul;49(1):99-102 PMID 16206190
  • Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorable-histology Wilms tumor: a report from the National Wilms Tumor Study Group. (Grundy PE, Breslow NE, Li S, Perlman E, Beckwith JB, Ritchey ML, Shamberger RC, Haase GM, D'Angio GJ, Donaldson M, Coppes MJ, Malogolowkin M, Shearer P, Thomas PR, Macklis R, Tomlinson G, Huff V, Green DM, National Wilms Tumor Study Group) J Clin Oncol 2005 Oct 10;23(29):7312-21 PMID 16129848
  • Post-transplant multiple myeloma in a pediatric renal transplant patient. (Tcheng WY, Said J, Hall T, Al-Akash S, Malogolowkin M, Feig SA) Pediatr Blood Cancer 2006 Aug;47(2):218-23 PMID 16086426
  • Amifostine does not protect against the ototoxicity of high-dose cisplatin combined with etoposide and bleomycin in pediatric germ-cell tumors: a Children's Oncology Group study. (Marina N, Chang KW, Malogolowkin M, London WB, Frazier AL, Womer RB, Rescorla F, Billmire DF, Davis MM, Perlman EJ, Giller R, Lauer SJ, Olson TA, Children's Oncology Group) Cancer 2005 Aug 15;104(4):841-7 PMID 15999362
  • Predictors of outcome in children with Langerhans cell histiocytosis. (Jubran RF, Marachelian A, Dorey F, Malogolowkin M) Pediatr Blood Cancer 2005 Jul;45(1):37-42 PMID 15768381
  • Management of Wilms' tumour: current practice and future goals. (Kalapurakal JA, Dome JS, Perlman EJ, Malogolowkin M, Haase GM, Grundy P, Coppes MJ) Lancet Oncol 2004 Jan;5(1):37-46 PMID 14700607
  • Fibrolamellar hepatocellular carcinoma in children and adolescents. (Katzenstein HM, Krailo MD, Malogolowkin MH, Ortega JA, Qu W, Douglass EC, Feusner JH, Reynolds M, Quinn JJ, Newman K, Finegold MJ, Haas JE, Sensel MG, Castleberry RP, Bowman LC) Cancer 2003 Apr 15;97(8):2006-12 PMID 12673731
  • Hepatocellular carcinoma in children and adolescents: results from the Pediatric Oncology Group and the Children's Cancer Group intergroup study. (Katzenstein HM, Krailo MD, Malogolowkin MH, Ortega JA, Liu-Mares W, Douglass EC, Feusner JH, Reynolds M, Quinn JJ, Newman K, Finegold MJ, Haas JE, Sensel MG, Castleberry RP, Bowman LC) J Clin Oncol 2002 Jun 15;20(12):2789-97 PMID 12065555
  • Treatment with nephrectomy only for small, stage I/favorable histology Wilms' tumor: a report from the National Wilms' Tumor Study Group. (Green DM, Breslow NE, Beckwith JB, Ritchey ML, Shamberger RC, Haase GM, D'Angio GJ, Perlman E, Donaldson M, Grundy PE, Weetman R, Coppes MJ, Malogolowkin M, Shearer P, Coccia P, Kletzel M, Thomas PR, Macklis R, Tomlinson G, Huff V, Newbury R, Weeks D) J Clin Oncol 2001 Sep 1;19(17):3719-24 PMID 11533093
  • Mycotic aneurysm of the thoracic aorta due to Aspergillus terreus: case report and review. (Silva ME, Malogolowkin MH, Hall TR, Sadeghi AM, Krogstad P) Clin Infect Dis 2000 Nov;31(5):1144-8 PMID 11073743
  • Presence of well-differentiated rhabdomyoblasts at the end of therapy for pelvic rhabdomyosarcoma: implications for the outcome. (Ortega JA, Rowland J, Monforte H, Malogolowkin M, Triche T) J Pediatr Hematol Oncol 2000 Mar-Apr;22(2):106-11 PMID 10779022
  • Feasibility and toxicity of chemoembolization for children with liver tumors. (Malogolowkin MH, Stanley P, Steele DA, Ortega JA) J Clin Oncol 2000 Mar;18(6):1279-84 PMID 10715298
  • Complications of cancer therapy in children: a radiologist's guide. (Parisi MT, Fahmy JL, Kaminsky CK, Malogolowkin MH) Radiographics 1999 Mar-Apr;19(2):283-97 PMID 10194780
  • Risk factors for early infection of central venous catheters in pediatric patients. (Shaul DB, Scheer B, Rokhsar S, Jones VA, Chan LS, Boody BA, Malogolowkin MH, Mason WH) J Am Coll Surg 1998 Jun;186(6):654-8 PMID 9632153
  • Chemotherapy plus local treatment in the management of intraocular retinoblastoma. (Murphree AL, Villablanca JG, Deegan WF 3rd, Sato JK, Malogolowkin M, Fisher A, Parker R, Reed E, Gomer CJ) Arch Ophthalmol 1996 Nov;114(11):1348-56 PMID 8906025
  • A prospective study of vancomycin pharmacokinetics and dosage requirements in pediatric cancer patients. (Chang D, Liem L, Malogolowkin M) Pediatr Infect Dis J 1994 Nov;13(11):969-74 PMID 7845750
  • Results of treatment of malignant germ cell tumors in 93 children: a report from the Childrens Cancer Study Group. (Ablin AR, Krailo MD, Ramsay NK, Malogolowkin MH, Isaacs H, Raney RB, Adkins J, Hays DM, Benjamin DR, Grosfeld JL) J Clin Oncol 1991 Oct;9(10):1782-92 PMID 1717667
  • Germ cell tumors in infancy and childhood: a 45-year experience. (Malogolowkin MH, Mahour GH, Krailo M, Ortega JA) Pediatr Pathol 1990;10(1-2):231-41 PMID 2156245
  • Immature teratomas: identification of patients at risk for malignant recurrence. (Malogolowkin MH, Ortega JA, Krailo M, Gonzalez O, Mahour GH, Landing BH, Siegel SE) J Natl Cancer Inst 1989 Jun 7;81(11):870-4 PMID 2470911
  • Tracing expert thinking in clinical trial design. (Malogolowkin MH, Horowitz RS, Ortega JA, Siegel SE, Hammond GD, Weiner JM) Comput Biomed Res 1989 Apr;22(2):190-208 PMID 2656077
  • Rhabdomyosarcoma of childhood. (Malogolowkin MH, Ortega JA) Pediatr Ann 1988 Apr;17(4):251, 254-68 PMID 3290813
  • Grants and Awards

  • Children's Operational Award (#9207826 01/01/2013 - 12/31/2013) Sponsor: Children's Hospital of Wisconsin
  • 2014 Children's Operational Award (#9208426 01/01/2014 - 04/30/2014) Sponsor: Children's Hospital of Wisconsin
  • Cancer Imaging Research Program (#9520223 02/01/2012 - 01/31/2017) PI of Diffusion-Weighted Imaging to Evaluate Cellularity of Solid Tumors in Children, Adolescents and Young Adults (Cancer Center-AHW) (#5520270)