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Paul S. Pagel MD, PhD Online Profile

Professor
Medical College of Wisconsin
Department: Anesthesiology
Division: Clinical
Program: Operating Room Service


Publications

  • Scholarly productivity of united states academic cardiothoracic anesthesiologists: influence of fellowship accreditation and transesophageal echocardiographic credentials on h-index and other citation bibliometrics. (Pagel PS, Hudetz JA) J Cardiothorac Vasc Anesth 2011 Oct;25(5):761-5 PMID 21546271
  • Postoperative cognitive dysfunction after noncardiac surgery: effects of metabolic syndrome. (Hudetz JA, Patterson KM, Amole O, Riley AV, Pagel PS) J Anesth 2011 Jun;25(3):337-44 PMID 21516370
  • Management of labor and delivery of a patient with Von Willebrand disease type 2A. (Amorde RW, Patel SN, Pagel PS) Int Anesthesiol Clin 2011;49(2):74-80 PMID 21441804
  • Sudden cardiac death resulting from acute coronary artery aneurysm occlusion: successful resuscitation and treatment of an adolescent boy with previously unrecognized Kawasaki disease. (Hadid D, Plambeck CJ, Nicolosi AC, Markan S, Pagel PS) Int Anesthesiol Clin 2011;49(2):42-51 PMID 21441798
  • Working the angles: continuous cardiac output through Doppler independence. (Pagel PS, Hudetz JA) Anesth Analg 2011 Apr;112(4):753-5 PMID 21430034
  • Persistent chest pain in a polysubstance abuser: an unusual consequence. (Radojevich LA, Pagel PS) J Cardiothorac Vasc Anesth 2012 Jun;26(3):532-4 PMID 21232980
  • Sudden onset of atrial flutter during continuous venovenous hemodialysis. (Brzezinski M, Kukreja J, Mitchell JD, Pagel PS, Tassone RF) J Cardiothorac Vasc Anesth 2012 Jun;26(3):535-6 PMID 21232978
  • Abnormal fibrillin-1 expression and chronic oxidative stress mediate endothelial mesenchymal transition in a murine model of systemic sclerosis. (Xu H, Zaidi M, Struve J, Jones DW, Krolikowski JG, Nandedkar S, Lohr NL, Gadicherla A, Pagel PS, Csuka ME, Pritchard KA, Weihrauch D) Am J Physiol Cell Physiol 2011 Mar;300(3):C550-6 PMID 21160034
  • A thin structure attached to the atrial septum: what is propping up the tent? (Pagel PS) J Cardiothorac Vasc Anesth 2012 Apr;26(2):346-8 PMID 21146424
  • Attitudes, patterns of recommendation, and communication of pediatric providers about complementary and alternative medicine in a large metropolitan children's hospital. (Kundu A, Tassone RF, Jimenez N, Seidel K, Valentine JK, Pagel PS) Clin Pediatr (Phila) 2011 Feb;50(2):153-8 PMID 21127080
  • Delayed cardioprotection by inhaled anesthetics. (Pagel PS, Hudetz JA) J Cardiothorac Vasc Anesth 2011 Dec;25(6):1125-40 PMID 21109464
  • Elevated postoperative inflammatory biomarkers are associated with short- and medium-term cognitive dysfunction after coronary artery surgery. (Hudetz JA, Gandhi SD, Iqbal Z, Patterson KM, Pagel PS) J Anesth 2011 Feb;25(1):1-9 PMID 21061037
  • A large mass on a newly implanted pulmonary artery catheter: thrombus, vegetation, or an anatomic explanation? (Loveday RK, Wanta BT, Nicolosi AC, Pagel PS) J Cardiothorac Vasc Anesth 2012 Feb;26(1):175-7 PMID 20864360
  • Reply. (Hudetz JA et al.) J Cardiothorac Vasc Anesth 2011 Apr;25(2):e9 PMID 20850988
  • Dizziness in a patient with a right atrial mass. (Iqbal Z, Sivils S, Pagel PS) J Cardiothorac Vasc Anesth 2012 Feb;26(1):172-4 PMID 20850987
  • A double-orifice, severely stenotic aortic valve: is leaflet perforation or extensive central calcification with near fusion the culprit? (Maqsood MA, Steward LM, Pagel PS) J Cardiothorac Vasc Anesth 2011 Dec;25(6):1223-5 PMID 20822919
  • Metabolic syndrome exacerbates short-term postoperative cognitive dysfunction in patients undergoing cardiac surgery: results of a pilot study. (Hudetz JA, Patterson KM, Iqbal Z, Gandhi SD, Pagel PS) J Cardiothorac Vasc Anesth 2011 Apr;25(2):282-7 PMID 20728380
  • In reply: extensive venous malformation: an alternative diagnosis to Klippel-TrĂ©naunay syndrome. (Holak EJ et al.) J Anesth 2010 Oct;24(5):823 PMID 20697918
  • Postoperative delirium and short-term cognitive dysfunction occur more frequently in patients undergoing valve surgery with or without coronary artery bypass graft surgery compared with coronary artery bypass graft surgery alone: results of a pilot study. (Hudetz JA, Iqbal Z, Gandhi SD, Patterson KM, Byrne AJ, Pagel PS) J Cardiothorac Vasc Anesth 2011 Oct;25(5):811-6 PMID 20655248
  • Feeling the pressure? Anterior mitral leaflet immobility in a patient with bicuspid aortic valve disease. (Dwarakanath K, Plambeck CJ, Markan S, Pagel PS) J Cardiothorac Vasc Anesth 2011 Oct;25(5):891-3 PMID 20638301
  • Facilitating the transition to practice: a weekend retreat curriculum for business-of-medicine education of United States anesthesiology residents. (Holak EJ, Kaslow O, Pagel PS) J Anesth 2010 Oct;24(5):807-10 PMID 20563736
  • CASE 3-2010 Dynamic partial obstruction of the tricuspid valve inlet produced by anterior mediastinal aspergillosis invading the right atrium. (Hansen TN, Plambeck CJ, Barron MJ, Pagel PS, DeAnda A, Neustein S) J Cardiothorac Vasc Anesth 2010 Jun;24(3):506-12 PMID 20510248
  • History of post-traumatic stress disorder is associated with impaired neuropsychometric performance after coronary artery surgery. (Hudetz JA, Gandhi SD, Iqbal Z, Patterson KM, Byrne AJ, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2010 Dec;24(6):964-8 PMID 20494591
  • Tricuspid regurgitation of varying severity: leaflet prolapse or pacemaker lead-induced obstruction? (Haake RM, Maqsood MA, Pinkerton C, Iqbal Z, Masroor S, Pagel PS) J Cardiothorac Vasc Anesth 2011 Aug;25(4):753-4 PMID 20417125
  • An image from the dark side of the stomach. (Eiseman MS, Iqbal Z, Markan S, Pagel PS) J Cardiothorac Vasc Anesth 2011 Jun;25(3):565-6 PMID 20399115
  • Preoperative dispositional optimism correlates with a reduced incidence of postoperative delirium and recovery of postoperative cognitive function in cardiac surgical patients. (Hudetz JA, Hoffmann RG, Patterson KM, Byrne AJ, Iqbal Z, Gandhi SD, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2010 Aug;24(4):560-7 PMID 20346702
  • Postoperative delirium is associated with postoperative cognitive dysfunction at one week after cardiac surgery with cardiopulmonary bypass. (Hudetz JA, Patterson KM, Byrne AJ, Pagel PS, Warltier DC) Psychol Rep 2009 Dec;105(3 Pt 1):921-32 PMID 20099555
  • Another potential anesthetic implication of body piercing. (Holak EJ, Schiller ED, Pagel PS) J Anesth 2010 Feb;24(1):152-3 PMID 20069315
  • Successful use of spinal anesthesia in a patient with severe Klippel-TrĂ©naunay syndrome associated with upper airway abnormalities and chronic Kasabach-Merritt coagulopathy. (Holak EJ, Pagel PS) J Anesth 2010 Feb;24(1):134-8 PMID 20054587
  • A history of alcohol dependence increases the incidence and severity of postoperative cognitive dysfunction in cardiac surgical patients. (Hudetz JA, Patterson KM, Byrne AJ, Iqbal Z, Gandhi SD, Warltier DC, Pagel PS) Int J Environ Res Public Health 2009 Nov;6(11):2725-39 PMID 20049218
  • Cardiac football or cause of severe tricuspid regurgitation? (Schiller ED, Maqsood MA, Pagel PS) J Cardiothorac Vasc Anesth 2010 Dec;24(6):1013-5 PMID 20005742
  • A rare cause of severe aortic insufficiency without stenosis: certainly not one of the usual suspects. (Dwarakanath K, De Vry DJ, Maqsood MA, Fons RA, Masroor S, Pagel PS) J Cardiothorac Vasc Anesth 2011 Feb;25(1):196-8 PMID 19880329
  • The poppies of Afghanistan. (Pagel PS) Anesth Analg 2009 Nov;109(5):1374-6 PMID 19843773
  • Cardioprotection by volatile anesthetics: established scientific principle or lingering clinical uncertainty? (Pagel PS) J Cardiothorac Vasc Anesth 2009 Oct;23(5):589-93 PMID 19789055
  • A duplicate middle scallop of the anterior mitral leaflet: benign curiosity, imaging artifact, or important pathology? (Onuora TO, Pagel PS) J Cardiothorac Vasc Anesth 2010 Dec;24(6):1010-2 PMID 19783159
  • Use of ECMO to temporize circulatory instability during severe Brugada electrical storm. (Pagel PS, Lilly RE, Nicolosi AC) Ann Thorac Surg 2009 Sep;88(3):982-3 PMID 19699933
  • The rings of Saturn in the aortic arch? An unusual consequence of cardiopulmonary bypass in an acute type-A aortic dissection. (Owen HL, Quintana JS, Matysiak B, Holak EJ, Markan S, Pagel PS) J Cardiothorac Vasc Anesth 2010 Oct;24(5):887-9 PMID 19646903
  • Neuroprotection by ketamine: a review of the experimental and clinical evidence. (Hudetz JA, Pagel PS) J Cardiothorac Vasc Anesth 2010 Feb;24(1):131-42 PMID 19640746
  • A simple method for obtaining a "ramped" laryngoscopy position after anesthetic induction. (Brzezinski M, Lee A, Holak EJ, Pagel PS) J Cardiothorac Vasc Anesth 2010 Jun;24(3):537-9 PMID 19640744
  • An elongated oval-shaped echolucent structure centered in the transverse aortic arch: evidence of a vascular disaster or a lucky break? (Pitts NA, Holak EJ, Kaslow O, Pagel PS) J Cardiothorac Vasc Anesth 2010 Aug;24(4):719-21 PMID 19640743
  • Perioperative implications of hereditary spherocytosis in coronary artery surgery. (Khatri V, Holak EJ, Pagel PS) J Cardiothorac Vasc Anesth 2010 Aug;24(4):636-8 PMID 19640740
  • Anterior chest discomfort and right neck pain in a young woman 2 days after an appendectomy. (Kaslow O, Holak EJ, Owen HL, Woosencraft D, Tisol WB, Pagel PS) J Cardiothorac Vasc Anesth 2010 Jun;24(3):519-22 PMID 19553134
  • Case 4--2009. Severe reexpansion pulmonary edema after minimally invasive aortic valve replacement: management using extracorporeal membrane oxygenation. (Shires AL, Green TM, Owen HL, Hansen TN, Iqbal Z, Markan S, Lilly RE, Pagel PS, Slinger PD, DeRose JJ Jr) J Cardiothorac Vasc Anesth 2009 Aug;23(4):549-54 PMID 19525125
  • Cardioprotection by noble gases. (Pagel PS) J Cardiothorac Vasc Anesth 2010 Feb;24(1):143-63 PMID 19467886
  • Severe allergic contact dermatitis resulting from occupational exposure to tincture of benzoin aerosol spray in an anesthesiologist. (Klein TG, Woehlck HJ, Pagel PS) J Anesth 2009;23(2):292-4 PMID 19444575
  • Ketamine attenuates post-operative cognitive dysfunction after cardiac surgery. (Hudetz JA, Iqbal Z, Gandhi SD, Patterson KM, Byrne AJ, Hudetz AG, Pagel PS, Warltier DC) Acta Anaesthesiol Scand 2009 Aug;53(7):864-72 PMID 19422355
  • Surgical repair of long-standing mitral valve prolapse: a case report and brief review of the literature. (Pagel PS, Haider N, Butler EG, Nicolosi AC) WMJ 2009 Feb;108(1):44-7 PMID 19326636
  • Transient metabolic alkalosis during early reperfusion abolishes helium preconditioning against myocardial infarction: restoration of cardioprotection by cyclosporin A in rabbits. (Pagel PS, Krolikowski JG) Anesth Analg 2009 Apr;108(4):1076-82 PMID 19299764
  • A cavity in the left ventricular outflow tract: a disastrous consequence of tooth decay? (Young M, Markan S, Hansen TN, Iqbal Z, Nicolosi AC, Pagel PS) J Cardiothorac Vasc Anesth 2010 Jun;24(3):513-5 PMID 19285432
  • Ketamine attenuates delirium after cardiac surgery with cardiopulmonary bypass. (Hudetz JA, Patterson KM, Iqbal Z, Gandhi SD, Byrne AJ, Hudetz AG, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2009 Oct;23(5):651-7 PMID 19231245
  • An object in the proximal left ventricular outflow tract during late diastole: aortic valve prolapse, mass, or normal anatomy? (Pagel PS, Shah JR, Novalija J, Markan S, Lilly RE) J Cardiothorac Vasc Anesth 2010 Apr;24(2):367-8 PMID 19231244
  • Morphine reduces the threshold of helium preconditioning against myocardial infarction: the role of opioid receptors in rabbits. (Pagel PS, Krolikowski JG, Amour J, Warltier DC, Weihrauch D) J Cardiothorac Vasc Anesth 2009 Oct;23(5):619-24 PMID 19231239
  • Xenon preconditioning: the role of prosurvival signaling, mitochondrial permeability transition and bioenergetics in rats. (Mio Y, Shim YH, Richards E, Bosnjak ZJ, Pagel PS, Bienengraeber M) Anesth Analg 2009 Mar;108(3):858-66 PMID 19224794
  • Perioperative implications of Morquio syndrome in a 31-year-old woman undergoing aortic valve replacement. (Pagel PS, Almassi GH) J Cardiothorac Vasc Anesth 2009 Dec;23(6):855-7 PMID 19201209
  • A rare cause of mitral regurgitation in an elderly man undergoing aortic valve replacement. (Shah JR, Deyo CN, Pagel PS) J Cardiothorac Vasc Anesth 2010 Feb;24(1):193-5 PMID 19101170
  • Remote exposure to xenon produces delayed preconditioning against myocardial infarction in vivo: additional evidence that noble gases are not biologically inert. (Pagel PS) Anesth Analg 2008 Dec;107(6):1768-71 PMID 19020115
  • To flow or not to flow: that is the question in this chronic aortic dissection. (Patel K, Lindenbaum L, Plambeck CJ, Marla R, Nicolosi AC, Pagel PS) J Cardiothorac Vasc Anesth 2008 Oct;22(5):788-9 PMID 18922445
  • Postconditioning by volatile anesthetics: salvaging ischemic myocardium at reperfusion by activation of prosurvival signaling. (Pagel PS) J Cardiothorac Vasc Anesth 2008 Oct;22(5):753-65 PMID 18922439
  • Sudden onset of sharp left-sided chest pain and hemoptysis in a young man with a history of childhood aortic coarctation repair. (Patel K, Ruttum DM, Olund TJ, Gandhi SD, Tisol WB, Nicolosi AC, Pagel PS) J Cardiothorac Vasc Anesth 2009 Apr;23(2):256-8 PMID 18834811
  • Atrial septal thickening in a patient with syncope: variant of lipomatous hypertrophy or cardiac neoplasm? (Markan S, Lindenbaum L, Iqbal Z, Novalija J, Almassi GH, Pagel PS) J Cardiothorac Vasc Anesth 2009 Jun;23(3):424-6 PMID 18834808
  • Recurrent chest pain and dyspnea on exertion in an elderly man: just another case of coronary artery disease or a more unusual cause for "angina"? (Poller KJ, Robinson DA, Markan S, Iqbal Z, Novalija J, Lilly RE, Pagel PS) J Cardiothorac Vasc Anesth 2009 Jun;23(3):421-3 PMID 18834805
  • New rocking motion of a prosthetic aortic valve: an unexpected echocardiographic finding 1 month after implantation. (Nelson RY, Markan S, Iqbal Z, Nicolosi AC, Lilly RE, Pagel PS) J Cardiothorac Vasc Anesth 2009 Aug;23(4):561-3 PMID 18834779
  • A patient with chronic hemodialysis-dependent end-stage renal disease presenting with mild dyspnea on exertion and a harsh systolic murmur. (John A, Robinson DA, Markan S, Nicolosi AC, Pagel PS) J Cardiothorac Vasc Anesth 2009 Apr;23(2):253-5 PMID 18834768
  • Progressive dyspnea on exertion in a patient with known coronary artery disease and a remote history of Hodgkin's lymphoma. (Braun AJ, Marla R, Schubert C, Iqbal Z, Markan S, Almassi GH, Pagel PS) J Cardiothorac Vasc Anesth 2008 Dec;22(6):932-4 PMID 18834763
  • Why the "Y"? A peculiar intraventricular structure associated with a posterior basal aneurysm. Diagnosis: isolated calcification of the distal posterior medial papillary muscle. (Pagel PS, Murphy RM, Iqbal Z, Gandhi SD, Markan S) J Cardiothorac Vasc Anesth 2009 Feb;23(1):118-20 PMID 18834758
  • Gradual development of unilateral Horner's syndrome in an otherwise asymptomatic elderly man. Diagnosis: right upper posterior mediastinal thoracic schwannoma. (Smith EE, Novalija J, Tisol WB, Pagel PS) J Cardiothorac Vasc Anesth 2009 Feb;23(1):115-7 PMID 18834757
  • A mobile threadlike structure in the left atrium: cor triatriatum, artifact, or thrombus? (Markan S, Haider N, Novalija J, Iqbal Z, Gandhi SD, Pagel PS) J Cardiothorac Vasc Anesth 2009 Aug;23(4):566-8 PMID 18834832
  • Incidental discovery of a large right atrial mass in a patient during evaluation for upper abdominal pain. (Novalija J, Lang T, Butler EG, Almassi GH, Pagel PS) J Cardiothorac Vasc Anesth 2009 Oct;23(5):729-31 PMID 18834833
  • Case report: delayed presentation of postural headache in an adolescent girl after microscopic lumbar discectomy. (Kundu A, Sano Y, Pagel PS) Can J Anaesth 2008 Oct;55(10):696-701 PMID 18835968
  • A 2-day history of shortness of breath and intermittent dull substernal chest pain in a 42-year-old man: a case of acute insecticide toxicity or something more ominous? (Pagel PS, Gandhi SD, Shah JR, Butler EG, Almassi GH) J Cardiothorac Vasc Anesth 2009 Oct;23(5):732-4 PMID 18834817
  • Inhibition of glycogen synthase kinase or the apoptotic protein p53 lowers the threshold of helium cardioprotection in vivo: the role of mitochondrial permeability transition. (Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D) Anesth Analg 2008 Sep;107(3):769-75 PMID 18713881
  • Induction of heat shock protein 70 and preconditioning by sevoflurane: a potent protective interaction against myocardial ischemia-reperfusion injury. (Pagel PS) Anesth Analg 2008 Sep;107(3):742-5 PMID 18713875
  • The mechanism of helium-induced preconditioning: a direct role for nitric oxide in rabbits. (Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D) Anesth Analg 2008 Sep;107(3):762-8 PMID 18713880
  • Pretty intraventricular rainbow or convincing evidence for a primary cause of heart failure? (Carroll B, Robinson DA, Markan S, Iqbal Z, Almassi GH, Pagel PS) J Cardiothorac Vasc Anesth 2008 Aug;22(4):633-5 PMID 18662646
  • Reactive oxygen species and mitochondrial adenosine triphosphate-regulated potassium channels mediate helium-induced preconditioning against myocardial infarction in vivo. (Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D) J Cardiothorac Vasc Anesth 2008 Aug;22(4):554-9 PMID 18662630
  • Anesthesiology, its mission, and 2007's "best" articles. (Pagel PS) Anesthesiology 2008 Jul;109(1):158; author reply 158 PMID 18580195
  • Intracardiac masses associated with permanent endocardial pacemaker lead erosion through the skin. (Gandhi SD, Shah B, Iqbal Z, Markan S, Novalija J, Pagel PS) J Cardiothorac Vasc Anesth 2008 Jun;22(3):492-4 PMID 18503947
  • Additive cardioprotection by ethanol and sevoflurane: are sarcolemmal K ATP channels also involved? (Pagel PS) Anesth Analg 2008 Jun;106(6):1926; author reply 1926-7 PMID 18499639
  • An Intracardiac UFO. (Pagel PS) J Cardiothorac Vasc Anesth 2008 Apr;22(2):332-3 PMID 18375346
  • A large, spherical echogenic object appearing in the left atrium during early left ventricular ejection. (Patel K, Pitts NA, Iqbal Z, Gandhi SD, Quinn TM, Pagel PS) J Cardiothorac Vasc Anesth 2008 Apr;22(2):321-3 PMID 18375344
  • Remote right ventricular rupture after coronary artery bypass graft surgery: a catastrophic complication of occult right ventricular infarction in a patient with a sternal infection. (Pagel PS, Iqbal Z, Gandhi SD, Novalija J, Markan S, May JA, Almassi GH) J Cardiothorac Vasc Anesth 2008 Apr;22(2):270-2 PMID 18375334
  • Simvastatin restores ischemic preconditioning in the presence of hyperglycemia through a nitric oxide-mediated mechanism. (Gu W, Kehl F, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2008 Apr;108(4):634-42 PMID 18362595
  • Massive retrograde acute type B aortic dissection in a postpartum woman with a family history of Marfan syndrome. (Gandhi SD, Iqbal Z, Markan S, Almassi GH, Pagel PS) J Clin Anesth 2008 Feb;20(1):50-3 PMID 18346611
  • Management of hereditary angioedema during off-pump coronary arterial surgery. (Pecsi SA, Almassi GH, Bojrab RB, Pagel PS) Ann Thorac Surg 2008 Mar;85(3):1079-81 PMID 18291204
  • Acute pericardial tamponade as a remote complication of a CardioSEAL atrial septal defect closure device. (Iqbal Z, Gandhi SD, Markan S, Olund TJ, May JA, Lilly RE, Pagel PS) J Cardiothorac Vasc Anesth 2008 Feb;22(1):90-1 PMID 18249337
  • Progressive dyspnea and exercise intolerance in an adult with a persistent childhood murmur. (Patel K, Shankar V, Plambeck CJ, Pagel PS) J Cardiothorac Vasc Anesth 2008 Feb;22(1):157-9 PMID 18249353
  • [Pseudomembranous supraglottitis with airway compromise in a patient with recurrent tonsillar carcinoma]. (Klein TG, Parkins DG, Gandhi SD, Iqbal Z, Schmeling WT, Pagel PS) Can J Anaesth 2008 Jan;55(1):42-6 PMID 18166747
  • Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection. (Jamnicki-Abegg M, Weihrauch D, Chiari PC, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) J Cardiovasc Pharmacol 2007 Dec;50(6):670-6 PMID 18091584
  • A rare cause of subtotal airway obstruction during anesthetic induction in a patient with facial trauma. (Holak EJ, Anderson RF, Pagel PS) J Cardiothorac Vasc Anesth 2007 Dec;21(6):903-5 PMID 18068078
  • When lack of addition really does add up. (Pagel PS) Anesth Analg 2007 Dec;105(6):1863; author reply 1863-4 PMID 18042898
  • An unusual complication of lumbar subarachnoid drainage catheter placement in a patient undergoing endovascular stent repair of a thoracic aortic aneurysm. (Chen P, Gandhi SD, Iqbal Z, Markan S, Novalija J, Signorino PR, Seabrook GR, Pagel PS) J Cardiothorac Vasc Anesth 2007 Oct;21(5):763-5 PMID 17905293
  • Management of ileostomy trauma produced by a dog bite in a patient with thoracic paraplegia. (Pagel PS, Scott JP, Schmeling WT, Donnell RF) Urology 2007 Aug;70(2):373.e8-9 PMID 17826522
  • Electroconvulsive therapy-induced asystole: occurrence after 39 previous uneventful treatments. (Holak EJ, Scott JP, Pagel PS) Can J Anaesth 2007 Sep;54(9):772-3 PMID 17766750
  • Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo. (Pagel PS, Krolikowski JG, Shim YH, Venkatapuram S, Kersten JR, Weihrauch D, Warltier DC, Pratt PF Jr) Anesth Analg 2007 Sep;105(3):562-9 PMID 17717207
  • Near total eclipse of the aortic valve: an echocardiographic penumbra caused by a mechanical mitral valve prosthesis and its clinical implications. (Vandrovec SM, Butler EG, May JA, Iqbal Z, Gandhi SD, Nicolosi AC, Pagel PS) J Cardiothorac Vasc Anesth 2007 Aug;21(4):610-1 PMID 17678800
  • Case 4-2007. Aprotinin-induced cardiovascular collapse after a negative test dose in a patient scheduled for repeat mitral valve surgery. (Beaulieu PL, Gandhi SD, Iqbal Z, Butler EG, Almassi GH, Pagel PS, Levy JH) J Cardiothorac Vasc Anesth 2007 Aug;21(4):597-601 PMID 17678797
  • Perioperative implications of charcot-marie-tooth disease during coronary artery bypass graft surgery. (Shankar V, Markan S, Gandhi SD, Iqbal Z, Novalija J, Nicolosi AC, Pagel PS) J Cardiothorac Vasc Anesth 2007 Aug;21(4):567-9 PMID 17678787
  • Repetitive generalized seizure-like activity during emergence from sevoflurane anesthesia. (Mohanram A, Kumar V, Iqbal Z, Markan S, Pagel PS) Can J Anaesth 2007 Aug;54(8):657-61 PMID 17666720
  • A triple-lumen aorta: an unusual manifestation of complex aortic pathology associated with crack cocaine abuse. (Feldhendler M, May JA, Gandhi SD, Iqbal Z, Butler EG, Lilly RE, Pagel PS) J Cardiothorac Vasc Anesth 2007 Jun;21(3):462-4 PMID 17544910
  • Suxamethonium-induced hyperkalaemia 6 weeks after chemoradiotherapy in a patient with rectal carcinoma. (Holak EJ, Connelly JF, Pagel PS) Br J Anaesth 2007 Jun;98(6):766-8 PMID 17470846
  • A widened mediastinum in a patient with a left parasternal stab wound. (Iqbal Z, Gandhi SD, Markan S, Nicolosi AC, Pagel PS) J Cardiothorac Vasc Anesth 2007 Apr;21(2):307-9 PMID 17418756
  • Anesthetics and echocardiographic assessment of left ventricular function: lessons learned from invasive analysis of cardiovascular mechanics. (Pagel PS) J Am Soc Echocardiogr 2007 Apr;20(4):440-1 PMID 17400131
  • Levosimendan in cardiac surgery: a unique drug for the treatment of perioperative left ventricular dysfunction or just another inodilator searching for a clinical application? (Pagel PS) Anesth Analg 2007 Apr;104(4):759-61 PMID 17377077
  • An unusual right atrial structure in a patient with a new diastolic murmur. (Iqbal Z, Gandhi SD, Kersten JR, Pagel PS) J Cardiothorac Vasc Anesth 2007 Feb;21(1):152-4 PMID 17289501
  • Inhibition of apoptotic protein p53 lowers the threshold of isoflurane-induced cardioprotection during early reperfusion in rabbits. (Venkatapuram S, Wang C, Krolikowski JG, Weihrauch D, Kersten JR, Warltier DC, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Dec;103(6):1400-5 PMID 17122210
  • Ischemic preconditioning, myocardial stunning and anesthesia. (Toller WG, Kersten JR, Pagel PS, Warltier DC) Curr Opin Anaesthesiol 2000 Feb;13(1):35-40 PMID 17016277
  • Nitrous oxide and preconditioning. (Pagel PS, Warltier DC) Anesthesiology 2006 Sep;105(3):630; author reply 631 PMID 16932006
  • Extracellular signal-regulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in rats. (Wang C, Weihrauch D, Schwabe DA, Bienengraeber M, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Aug;103(2):281-8, table of contents PMID 16861403
  • Gender-specificity of delayed preconditioning by isoflurane in rabbits: potential role of endothelial nitric oxide synthase. (Wang C, Chiari PC, Weihrauch D, Krolikowski JG, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Aug;103(2):274-80, table of contents PMID 16861402
  • Cardioprotection by volatile anesthetics: new applications for old drugs? (Pratt PF Jr, Wang C, Weihrauch D, Bienengraeber MW, Kersten JR, Pagel PS, Warltier DC) Curr Opin Anaesthesiol 2006 Aug;19(4):397-403 PMID 16829721
  • Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling. (LaDisa JF Jr, Olson LE, Douglas HA, Warltier DC, Kersten JR, Pagel PS) Biomed Eng Online 2006;5:40 PMID 16780592
  • A circular structure in the aortic outflow tract during diastole: an unusual complication of cocaine abuse. (Alosman A, Bress JM, Bek E, Almassi GH, Pagel PS) J Cardiothorac Vasc Anesth 2006 Jun;20(3):458-60 PMID 16750754
  • The influence of B-cell lymphoma 2 protein, an antiapoptotic regulator of mitochondrial permeability transition, on isoflurane-induced and ischemic postconditioning in rabbits. (Wang C, Neff DA, Krolikowski JG, Weihrauch D, Bienengraeber M, Warltier DC, Kersten JR, Pagel PS) Anesth Analg 2006 May;102(5):1355-60 PMID 16632808
  • Inhibition of glycogen synthase kinase enhances isoflurane-induced protection against myocardial infarction during early reperfusion in vivo. (Pagel PS, Krolikowski JG, Neff DA, Weihrauch D, Bienengraeber M, Kersten JR, Warltier DC) Anesth Analg 2006 May;102(5):1348-54 PMID 16632807
  • Ischemia reperfusion dysfunction changes model-estimated kinetics of myofilament interaction due to inotropic drugs in isolated hearts. (Rhodes SS, Camara AK, Ropella KM, Audi SH, Riess ML, Pagel PS, Stowe DF) Biomed Eng Online 2006;5:16 PMID 16512898
  • Role of Erk1/2, p70s6K, and eNOS in isoflurane-induced cardioprotection during early reperfusion in vivo. (Krolikowski JG, Weihrauch D, Bienengraeber M, Kersten JR, Warltier DC, Pagel PS) Can J Anaesth 2006 Feb;53(2):174-82 PMID 16434759
  • Inhibition of mitochondrial permeability transition enhances isoflurane-induced cardioprotection during early reperfusion: the role of mitochondrial KATP channels. (Krolikowski JG, Bienengraeber M, Weihrauch D, Warltier DC, Kersten JR, Pagel PS) Anesth Analg 2005 Dec;101(6):1590-6 PMID 16301224
  • Ischemia-reperfusion injury changes the dynamics of Ca2+-contraction coupling due to inotropic drugs in isolated hearts. (Rhodes SS, Ropella KM, Camara AK, Chen Q, Riess ML, Pagel PS, Stowe DF) J Appl Physiol 2006 Mar;100(3):940-50 PMID 16282437
  • Axial stent strut angle influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics models of stent foreshortening. (LaDisa JF Jr, Olson LE, Hettrick DA, Warltier DC, Kersten JR, Pagel PS) Biomed Eng Online 2005;4:59 PMID 16250918
  • Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression. (Jamnicki-Abegg M, Weihrauch D, Pagel PS, Kersten JR, Bosnjak ZJ, Warltier DC, Bienengraeber MW) Anesthesiology 2005 Nov;103(5):1006-14 PMID 16249675
  • Aggressive control of intraoperative blood glucose concentration: a shifting paradigm? (Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2005 Oct;103(4):677-8 PMID 16192757
  • Morphine enhances isoflurane-induced postconditioning against myocardial infarction: the role of phosphatidylinositol-3-kinase and opioid receptors in rabbits. (Weihrauch D, Krolikowski JG, Bienengraeber M, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2005 Oct;101(4):942-9, table of contents PMID 16192500
  • Intraoperative iatrogenic acute pericardial tamponade: use of rescue transesophageal echocardiography in a patient undergoing orthotopic liver transplantation. (Sharma A, Pagel PS, Bhatia A) J Cardiothorac Vasc Anesth 2005 Jun;19(3):364-6 PMID 16130066
  • Role of endothelial nitric oxide synthase as a trigger and mediator of isoflurane-induced delayed preconditioning in rabbit myocardium. (Chiari PC, Bienengraeber MW, Weihrauch D, Krolikowski JG, Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2005 Jul;103(1):74-83 PMID 15983459
  • Cardioprotection by volatile anesthetics. (Bienengraeber MW, Weihrauch D, Kersten JR, Pagel PS, Warltier DC) Vascul Pharmacol 2005 Apr-May;42(5-6):243-52 PMID 15922257
  • Microfocal X-ray computed tomography post-processing operations for optimizing reconstruction volumes of stented arteries during 3D computational fluid dynamics modeling. (Ladisa JF Jr, Olson LE, Ropella KM, Molthen RC, Haworth ST, Kersten JR, Warltier DC, Pagel PS) Comput Methods Programs Biomed 2005 Aug;79(2):121-34 PMID 15894401
  • Antegrade iliac artery stent implantation for the temporal and spatial examination of stent-induced neointimal hyperplasia and alterations in regional fluid dynamics. (LaDisa JF Jr, Meier HT, Olson LE, Kersten JR, Warltier DC, Pagel PS) J Pharmacol Toxicol Methods 2005 Mar-Apr;51(2):115-21 PMID 15767204
  • Alterations in wall shear stress predict sites of neointimal hyperplasia after stent implantation in rabbit iliac arteries. (LaDisa JF Jr, Olson LE, Molthen RC, Hettrick DA, Pratt PF, Hardel MD, Kersten JR, Warltier DC, Pagel PS) Am J Physiol Heart Circ Physiol 2005 May;288(5):H2465-75 PMID 15653759
  • Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: evidence for anesthetic-induced postconditioning in rabbits. (Chiari PC, Bienengraeber MW, Pagel PS, Krolikowski JG, Kersten JR, Warltier DC) Anesthesiology 2005 Jan;102(1):102-9 PMID 15618793
  • Circumferential vascular deformation after stent implantation alters wall shear stress evaluated with time-dependent 3D computational fluid dynamics models. (LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol 2005 Mar;98(3):947-57 PMID 15531564
  • Intravenous emulsified halogenated anesthetics produce acute and delayed preconditioning against myocardial infarction in rabbits. (Chiari PC, Pagel PS, Tanaka K, Krolikowski JG, Ludwig LM, Trillo RA Jr, Puri N, Kersten JR, Warltier DC) Anesthesiology 2004 Nov;101(5):1160-6 PMID 15505452
  • Preconditioning by isoflurane is mediated by reactive oxygen species generated from mitochondrial electron transport chain complex III. (Ludwig LM, Tanaka K, Eells JT, Weihrauch D, Pagel PS, Kersten JR, Warltier DC) Anesth Analg 2004 Nov;99(5):1308-15; table of contents PMID 15502022
  • Chronic hyperglycemia attenuates coronary collateral development and impairs proliferative properties of myocardial interstitial fluid by production of angiostatin. (Weihrauch D, Lohr NL, Mraovic B, Ludwig LM, Chilian WM, Pagel PS, Warltier DC, Kersten JR) Circulation 2004 May 18;109(19):2343-8 PMID 15136506
  • Mechanisms of cardioprotection by volatile anesthetics. (Tanaka K, Ludwig LM, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):707-21 PMID 15108989
  • Cyclooxygenase-2 mediates ischemic, anesthetic, and pharmacologic preconditioning in vivo. (Alcindor D, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2004 Mar;100(3):547-54 PMID 15108967
  • Protein kinase C translocation and Src protein tyrosine kinase activation mediate isoflurane-induced preconditioning in vivo: potential downstream targets of mitochondrial adenosine triphosphate-sensitive potassium channels and reactive oxygen species. (Ludwig LM, Weihrauch D, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):532-9 PMID 15108965
  • Isoflurane produces delayed preconditioning against myocardial ischemia and reperfusion injury: role of cyclooxygenase-2. (Tanaka K, Ludwig LM, Krolikowski JG, Alcindor D, Pratt PF, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):525-31 PMID 15108964
  • Cardioprotection by glucose-insulin-potassium: dependence on KATP channel opening and blood glucose concentration before ischemia. (LaDisa JF Jr, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H601-7 PMID 15044191
  • Mechanisms of myocardial protection produced by chronic ethanol consumption. (Pagel PS, Kersten JR, Warltier DC) Pathophysiology 2004 Apr;10(2):121-9 PMID 15006418
  • Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery. (LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Audi SH, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol 2004 Jul;97(1):424-30; discussion 416 PMID 14766776
  • Influence of isoflurane on left atrial function in dogs with pacing-induced cardiomyopathy: evaluation with pressure-volume relationships. (Kehl F, Ladisa JF Jr, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2003 Dec;17(6):709-14 PMID 14689410
  • An automated coronary artery occlusion device for stimulating collateral development in vivo. (Rys R, LaDisa JF Jr, Tessmer JP, Gu W, Kersten JR, Warltier DC, Pagel PS) J Pharmacol Toxicol Methods 2002 Sep-Oct;48(2):111-8 PMID 14565568
  • Three-dimensional computational fluid dynamics modeling of alterations in coronary wall shear stress produced by stent implantation. (LaDisa JF Jr, Guler I, Olson LE, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Ann Biomed Eng 2003 Sep;31(8):972-80 PMID 12918912
  • Reactive oxygen species are critical mediators of coronary collateral development in a canine model. (Gu W, Weihrauch D, Tanaka K, Tessmer JP, Pagel PS, Kersten JR, Chilian WM, Warltier DC) Am J Physiol Heart Circ Physiol 2003 Oct;285(4):H1582-9 PMID 12816750
  • N-acetylcysteine restores isoflurane-induced preconditioning against myocardial infarction during hyperglycemia. (Kehl F, Krolikowski JG, Weihrauch D, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2003 Jun;98(6):1384-90 PMID 12766647
  • Atrial pacing lead location alters the hemodynamic effects of atrial-ventricular delay in dogs with pacing induced cardiomyopathy. (Hettrick DA, Mittelstadt JR, Kehl F, Kress TT, Tessmer JP, Krolikowski JG, Kersten JR, Warltier DC, Pagel PS) Pacing Clin Electrophysiol 2003 Apr;26(4 Pt 1):853-61 PMID 12715846
  • Adenosine type 1 (A1) receptors mediate protection against myocardial infarction produced by chronic, intermittent ingestion of ethanol in dogs. (Kehl F, Krolikowski JG, LaDisa JF Jr, Kersten JR, Warltier DC, Pagel PS) Int J Cardiol 2003 Apr;88(2-3):175-82 PMID 12714196
  • Mechanical function of the left atrium: new insights based on analysis of pressure-volume relations and Doppler echocardiography. (Pagel PS, Kehl F, Gare M, Hettrick DA, Kersten JR, Warltier DC) Anesthesiology 2003 Apr;98(4):975-94 PMID 12657862
  • Mitochondrial adenosine triphosphate-regulated potassium channel opening acts as a trigger for isoflurane-induced preconditioning by generating reactive oxygen species. (Tanaka K, Weihrauch D, Ludwig LM, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2003 Apr;98(4):935-43 PMID 12657856
  • Modifying cardiovascular risk in diabetes mellitus. (Gu W, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2003 Mar;98(3):774-9 PMID 12606925
  • Morphine enhances pharmacological preconditioning by isoflurane: role of mitochondrial K(ATP) channels and opioid receptors. (Ludwig LM, Patel HH, Gross GJ, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2003 Mar;98(3):705-11 PMID 12606915
  • Perioperative considerations in the patient with a left ventricular assist device. (Nicolosi AC, Pagel PS) Anesthesiology 2003 Feb;98(2):565-70 PMID 12552217
  • Reactive oxygen species modulate coronary wall shear stress and endothelial function during hyperglycemia. (Gross ER, LaDisa JF Jr, Weihrauch D, Olson LE, Kress TT, Hettrick DA, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2003 May;284(5):H1552-9 PMID 12543642
  • Cross-bridge kinetics modeled from myoplasmic [Ca2+] and LV pressure at 17 degrees C and after 37 degrees C and 17 degrees C ischemia. (Rhodes SS, Ropella KM, Audi SH, Camara AK, Kevin LG, Pagel PS, Stowe DF) Am J Physiol Heart Circ Physiol 2003 Apr;284(4):H1217-29 PMID 12531735
  • Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. (Tanaka K, Weihrauch D, Kehl F, Ludwig LM, LaDisa JF Jr, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2002 Dec;97(6):1485-90 PMID 12459675
  • An intramyocardial catheter for repeated in vivo sampling of interstitial fluid. (Tessmer JP, Pagel PS, Weihrauch D, Ludwig LM, Chilian WM, Kersten JR, Warltier DC) J Pharmacol Toxicol Methods 2002 Mar-Apr;47(2):73-8 PMID 12459145
  • Isoflurane does not produce a second window of preconditioning against myocardial infarction in vivo. (Kehl F, Pagel PS, Krolikowski JG, Gu W, Toller W, Warltier DC, Kersten JR) Anesth Analg 2002 Nov;95(5):1162-8, table of contents PMID 12401584
  • Stent implantation alters coronary artery hemodynamics and wall shear stress during maximal vasodilation. (LaDisa JF Jr, Hettrick DA, Olson LE, Guler I, Gross ER, Kress TT, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol 2002 Dec;93(6):1939-46 PMID 12391052
  • Increases in coronary collateral blood flow produced by sevoflurane are mediated by calcium-activated potassium (BKCa) channels in vivo. (Kehl F, Krolikowski JG, Tessmer JP, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2002 Sep;97(3):725-31 PMID 12218541
  • Atrial pacing lead location alters the effects of atrioventricular delay on atrial and ventricular hemodynamics. (Hettrick DA, Euler DE, Pagel PS, Musley SK, Warman EN, Ziegler PD, Mehra R) Pacing Clin Electrophysiol 2002 Jun;25(6):888-96 PMID 12137340
  • Editorial view: anesthetic preconditioning: serendipity and science. (Warltier DC, Kersten JR, Pagel PS, Gross GJ) Anesthesiology 2002 Jul;97(1):1-3 PMID 12131096
  • Attitudes of anesthesiologists about addiction and its treatment: a survey of Illinois and Wisconsin members of the American Society of Anesthesiologists. (May JA, Warltier DC, Pagel PS) J Clin Anesth 2002 Jun;14(4):284-9 PMID 12088813
  • Propofol alters left atrial function evaluated with pressure-volume relations in vivo. (Kehl F, Kress TT, Mraovic B, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2002 Jun;94(6):1421-6, table of contents PMID 12031999
  • Reactive oxygen species contribute to contractile dysfunction following rapid ventricular pacing in dogs. (Gare M, Mraovic B, Kehl F, Kersten JR, Warltier DC, Pagel PS) Int J Cardiol 2002 May;83(2):125-31 PMID 12007684
  • Isoflurane-induced preconditioning is attenuated by diabetes. (Tanaka K, Kehl F, Gu W, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2002 Jun;282(6):H2018-23 PMID 12003806
  • The role of mitochondrial and sarcolemmal K(ATP) channels in canine ethanol-induced preconditioning in vivo. (Pagel PS, Krolikowski JG, Kehl F, Mraovic B, Kersten JR, Warltier DC) Anesth Analg 2002 Apr;94(4):841-8, table of contents PMID 11916782
  • Is isoflurane-induced preconditioning dose related? (Kehl F, Krolikowski JG, Mraovic B, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2002 Mar;96(3):675-80 PMID 11873044
  • Hyperglycemia prevents isoflurane-induced preconditioning against myocardial infarction. (Kehl F, Krolikowski JG, Mraovic B, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2002 Jan;96(1):183-8 PMID 11753019
  • Hyperglycemia reduces coronary collateral blood flow through a nitric oxide-mediated mechanism. (Kersten JR, Toller WG, Tessmer JP, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2001 Nov;281(5):H2097-104 PMID 11668071
  • Desflurane, sevoflurane, and isoflurane affect left atrial active and passive mechanical properties and impair left atrial-left ventricular coupling in vivo: analysis using pressure-volume relations. (Gare M, Schwabe DA, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2001 Sep;95(3):689-98 PMID 11575543
  • Conscious sedation with midazolam or propofol does not alter left ventricular diastolic performance in patients with preexisting diastolic dysfunction: a transmitral and tissue Doppler transthoracic echocardiography study. (Gare M, Parail A, Milosavljevic D, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2001 Oct;93(4):865-71 PMID 11574347
  • Hyperglycemia: an independent predictor of cardiovascular risk. (Kersten JR, Pagel PS, Warltier D) J Cardiothorac Vasc Anesth 2001 Jun;15(3):404-6 PMID 11426382
  • The patient recovering from alcohol or drug addiction: special issues for the anesthesiologist. (May JA, White HC, Leonard-White A, Warltier DC, Pagel PS) Anesth Analg 2001 Jun;92(6):1601-8 PMID 11375854
  • Diabetes and hyperglycemia impair activation of mitochondrial K(ATP) channels. (Kersten JR, Montgomery MW, Ghassemi T, Gross ER, Toller WG, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2001 Apr;280(4):H1744-50 PMID 11247788
  • Ethanol enhances the functional recovery of stunned myocardium independent of K(ATP) channels in dogs. (Gross ER, Gare M, Toller WG, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2001 Feb;92(2):299-305 PMID 11159220
  • K(ATP) channels mediate the beneficial effects of chronic ethanol ingestion. (Pagel PS, Toller WG, Gross ER, Gare M, Kersten JR, Warltier DC) Am J Physiol Heart Circ Physiol 2000 Nov;279(5):H2574-9 PMID 11045996
  • Perioperative considerations in a patient with orthostatic intolerance syndrome. (McHaourab A, Mazzeo AJ, May JA, Pagel PS) Anesthesiology 2000 Aug;93(2):571-3 PMID 10910484
  • Sarcolemmal and mitochondrial adenosine triphosphate- dependent potassium channels: mechanism of desflurane-induced cardioprotection. (Toller WG, Gross ER, Kersten JR, Pagel PS, Gross GJ, Warltier DC) Anesthesiology 2000 Jun;92(6):1731-9 PMID 10839925
  • Isoflurane preconditions myocardium against infarction via activation of inhibitory guanine nucleotide binding proteins. (Toller WG, Kersten JR, Gross ER, Pagel PS, Warltier DC) Anesthesiology 2000 May;92(5):1400-7 PMID 10781287
  • Correlation of esophageal conductance measurements with aortic and left ventricular diameters and stroke volume. (Hettrick DA, Battocletti JH, Pagel PS, Vurek GG, Tessmer JP, Kersten JR, Warltier DC) IEEE Trans Biomed Eng 2000 Apr;47(4):559-64 PMID 10763303
  • Diabetes abolishes ischemic preconditioning: role of glucose, insulin, and osmolality. (Kersten JR, Toller WG, Gross ER, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2000 Apr;278(4):H1218-24 PMID 10749717
  • Approaches to the prevention of perioperative myocardial ischemia. (Warltier DC, Pagel PS, Kersten JR) Anesthesiology 2000 Jan;92(1):253-9 PMID 10638923
  • Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels. (Kersten JR, Montgomery MW, Pagel PS, Warltier DC) Anesth Analg 2000 Jan;90(1):5-11 PMID 10624967
  • Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs. (Toller WG, Kersten JR, Pagel PS, Hettrick DA, Warltier DC) Anesthesiology 1999 Nov;91(5):1437-46 PMID 10551596
  • Multifactorial basis for coronary collateralization: a complex adaptive response to ischemia. (Kersten JR, Pagel PS, Chilian WM, Warltier DC) Cardiovasc Res 1999 Jul;43(1):44-57 PMID 10536689
  • Isoflurane-enhanced recovery of canine stunned myocardium: role for protein kinase C? (Toller WG, Montgomery MW, Pagel PS, Hettrick DA, Warltier DC, Kersten JR) Anesthesiology 1999 Sep;91(3):713-22 PMID 10485783
  • Levosimendan enhances cardiac performance after cardiopulmonary bypass: a prospective, randomized placebo-controlled trial. (Nijhawan N, Nicolosi AC, Montgomery MW, Aggarwal A, Pagel PS, Warltier DC) J Cardiovasc Pharmacol 1999 Aug;34(2):219-28 PMID 10445673
  • Changes in passive but not active mechanical properties predict recovery of function of stunned myocardium. (Schmeling TJ, Hettrick DA, Kersten JR, Pagel PS, Warltier DC) Ann Biomed Eng 1999 Mar-Apr;27(2):131-40 PMID 10199689
  • Sevoflurane selectively increases coronary collateral blood flow independent of KATP channels in vivo. (Kersten JR, Schmeling T, Tessmer J, Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1999 Jan;90(1):246-56 PMID 9915334
  • RSR13, a synthetic allosteric modifier of hemoglobin, enhances recovery of stunned myocardium in dogs. (Pagel PS, Hettrick DA, Montgomery MW, Kersten JR, Warltier DC) Adv Exp Med Biol 1998;454:527-31 PMID 9889932
  • Ischemia-induced coronary collateral angiogenesis. (Weihrauch D, Tessmer JP, Kersten JR, Pagel PS, Hettrick DA, Chilian WM, Warltier DC) Adv Exp Med Biol 1998;454:281-6 PMID 9889902
  • Cardiovascular effects of xenon in isoflurane-anesthetized dogs with dilated cardiomyopathy. (Hettrick DA, Pagel PS, Kersten JR, Tessmer JP, Bosnjak ZJ, Georgieff M, Warltier DC) Anesthesiology 1998 Nov;89(5):1166-73 PMID 9822005
  • Propofol, but not thiopentone or etomidate, enhances isoflurane-induced coronary vasodilatation in dogs. (Pagel PS, Hettrick DA, Kersten JR, Lowe D, Warltier DC) Can J Anaesth 1998 Aug;45(8):809-17 PMID 9793674
  • Desflurane and isoflurane produce similar alterations in systemic and pulmonary hemodynamics and arterial oxygenation in patients undergoing one-lung ventilation during thoracotomy. (Pagel PS, Fu JL, Damask MC, Davis RF, Samuelson PN, Howie MB, Warltier DC) Anesth Analg 1998 Oct;87(4):800-7 PMID 9768773
  • Dexmedetomidine produces similar alterations in the determinants of left ventricular afterload in conscious dogs before and after the development of pacing-induced cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Warltier DC) Anesthesiology 1998 Sep;89(3):741-8 PMID 9743413
  • Interpretation of nonpulsatile arterial pressure-flow relations during cardiopulmonary bypass. (Hettrick DA, Kersten JR, Pagel PS, Warltier DC) Anesth Analg 1998 Sep;87(3):743 PMID 9728869
  • A novel alpha 2-adrenoceptor antagonist attenuates the early, but preserves the late cardiovascular effects of intravenous dexmedetomidine in conscious dogs. (Pagel PS, Proctor LT, Devcic A, Hettrick DA, Kersten JR, Tessmer JP, Farber NE, Schmeling WT, Warltier DC) J Cardiothorac Vasc Anesth 1998 Aug;12(4):429-34 PMID 9713732
  • Acute hyperglycemia abolishes ischemic preconditioning in vivo. (Kersten JR, Schmeling TJ, Orth KG, Pagel PS, Warltier DC) Am J Physiol 1998 Aug;275(2 Pt 2):H721-5 PMID 9683464
  • Cardiovascular effects of verapamil enantiomer combinations in conscious dogs. (Pagel PS, Hettrick DA, Lowe D, Gowrie PW, Kersten JR, Bosnjak ZJ, Warltier DC) Eur J Pharmacol 1998 May 8;348(2-3):213-21 PMID 9652336
  • Etomidate adversely alters determinants of left ventricular afterload in dogs with dilated cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Tessmer JP, Lowe D, Warltier DC) Anesth Analg 1998 May;86(5):932-8 PMID 9585271
  • RSR13, a synthetic modifier of hemoglobin-oxygen affinity, enhances the recovery of stunned myocardium in anesthetized dogs. (Pagel PS, Hettrick DA, Montgomery MW, Kersten JR, Steffen RP, Warltier DC) J Pharmacol Exp Ther 1998 Apr;285(1):1-8 PMID 9535987
  • Activation of adenosine triphosphate-regulated potassium channels: mediation of cellular and organ protection. (Kersten JR, Gross GJ, Pagel PS, Warltier DC) Anesthesiology 1998 Feb;88(2):495-513 PMID 9477071
  • Cardiovascular effects of propofol in dogs with dilated cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Lowe D, Warltier DC) Anesthesiology 1998 Jan;88(1):180-9 PMID 9447871
  • Isoflurane and halothane do not alter the enhanced afterload sensitivity of left ventricular relaxation in dogs with pacing-induced cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Tessmer JP, Lowe D, Warltier DC) Anesthesiology 1997 Oct;87(4):952-62 PMID 9357899
  • The effects of isoflurane and halothane on left ventricular afterload in dogs with dilated cardiomyopathy. (Hettrick DA, Pagel PS, Kersten JR, Lowe D, Warltier DC) Anesth Analg 1997 Nov;85(5):979-86 PMID 9356087
  • Hemodynamic effects of repetitive cocaine administration. (Pagel PS, Warltier DC) Circulation 1997 Aug 5;96(3):1050 PMID 9264524
  • Isoflurane mimics ischemic preconditioning via activation of K(ATP) channels: reduction of myocardial infarct size with an acute memory phase. (Kersten JR, Schmeling TJ, Pagel PS, Gross GJ, Warltier DC) Anesthesiology 1997 Aug;87(2):361-70 PMID 9286901
  • Positive inotropic and lusitropic effects of triiodothyronine in conscious dogs with pacing-induced cardiomyopathy. (Jamall IN, Pagel PS, Hettrick DA, Lowe D, Kersten JR, Tessmer JP, Warltier DC) Anesthesiology 1997 Jul;87(1):102-9 PMID 9232140
  • Intracoronary levosimendan enhances contractile function of stunned myocardium. (Jamali IN, Kersten JR, Pagel PS, Hettrick DA, Warltier DC) Anesth Analg 1997 Jul;85(1):23-9 PMID 9212117
  • Levosimendan enhances left ventricular systolic and diastolic function in conscious dogs with pacing-induced cardiomyopathy. (Pagel PS, McGough MF, Hettrick DA, Lowe D, Tessmer JP, Jamali IN, Warltier DC) J Cardiovasc Pharmacol 1997 May;29(5):563-73 PMID 9213196
  • Temporal dependence of coronary collateral development. (Kersten JR, McGough MF, Pagel PS, Tessmer JP, Warltier DC) Cardiovasc Res 1997 May;34(2):306-12 PMID 9205544
  • Role of adenosine in isoflurane-induced cardioprotection. (Kersten JR, Orth KG, Pagel PS, Mei DA, Gross GJ, Warltier DC) Anesthesiology 1997 May;86(5):1128-39 PMID 9158363
  • Alterations in canine left ventricular-arterial coupling and mechanical efficiency produced by propofol. (Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1997 May;86(5):1088-93 PMID 9158358
  • Effects of isoflurane and propofol on arterial mechanical properties. (Hettrick DA, Pagel PS, Warltier DC) Anesth Analg 1997 Apr;84(4):940-1 PMID 9085995
  • Effects of levosimendan on left ventricular function: correlation with plasma concentrations in conscious dogs. (McGough MF, Pagel PS, Lowe D, Hettrick DA, Kersten JR, Warltier DC) J Cardiothorac Vasc Anesth 1997 Feb;11(1):49-53 PMID 9058220
  • Increases in inotropic state without change in heart rate: combined use of dobutamine and zatebradine in conscious dogs. (Hettrick DA, Pagel PS, Lowe D, Tessmer JP, Warltier DC) Eur J Pharmacol 1996 Dec 5;316(2-3):237-44 PMID 8982692
  • Isoflurane and halothane produce similar alterations in aortic distensibility and characteristic aortic impedance. (Hettrick DA, Pagel PS, Warltier DC) Anesth Analg 1996 Dec;83(6):1166-72 PMID 8942580
  • Influence of levosimendan, pimobendan, and milrinone on the regional distribution of cardiac output in anaesthetized dogs. (Pagel PS, Hettrick DA, Warltier DC) Br J Pharmacol 1996 Oct;119(3):609-15 PMID 8894186
  • Mechanism of myocardial protection by isoflurane. Role of adenosine triphosphate-regulated potassium (KATP) channels. (Kersten JR, Schmeling TJ, Hettrick DA, Pagel PS, Gross GJ, Warltier DC) Anesthesiology 1996 Oct;85(4):794-807; discussion 27A PMID 8873550
  • Isoflurane, but not halothane, improves indices of diastolic performance in dogs with rapid ventricular, pacing-induced cardiomyopathy. (Pagel PS, Lowe D, Hettrick DA, Jamali IN, Kersten JR, Tessmer JP, Warltier DC) Anesthesiology 1996 Sep;85(3):644-54 PMID 8853096
  • Desflurane, sevoflurane, and isoflurane impair canine left ventricular-arterial coupling and mechanical efficiency. (Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1996 Aug;85(2):403-13 PMID 8712457
  • Comparison of the effects of levosimendan, pimobendan, and milrinone on canine left ventricular-arterial coupling and mechanical efficiency. (Pagel PS, Hettrick DA, Warltier DC) Basic Res Cardiol 1996 Jul-Aug;91(4):296-307 PMID 8874779
  • Levosimendan potentiates the inotropic actions of dopamine in conscious dogs. (McGough MF, Pagel PS, Lowe D, Hettrick DA, Warltier DC) J Cardiovasc Pharmacol 1996 Jul;28(1):36-47 PMID 8797134
  • Glyburide, a KATP channel antagonist, attenuates the cardioprotective effects of isoflurane in stunned myocardium. (Kersten JR, Lowe D, Hettrick DA, Pagel PS, Gross GJ, Warltier DC) Anesth Analg 1996 Jul;83(1):27-33 PMID 8659760
  • Influence of volatile anesthetics on left ventricular afterload in vivo. Differences between desflurane and sevoflurane. (Lowe D, Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1996 Jul;85(1):112-20 PMID 8694356
  • Comparison of the cardiovascular effects of two novel superoxide dismutase mimetics, SC-55858 and SC-54417, in conscious dogs. (Lowe D, Pagel PS, McGough MF, Hettrick DA, Warltier DC) Eur J Pharmacol 1996 May 23;304(1-3):81-6 PMID 8813587
  • Propofol alters left ventricular afterload as evaluated by aortic input impedance in dogs. (Lowe D, Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1996 Feb;84(2):368-76 PMID 8602668
  • Desflurane and isoflurane exert modest beneficial actions on left ventricular diastolic function during myocardial ischemia in dogs. (Pagel PS, Hettrick DA, Lowe D, Tessmer JP, Warltier DC) Anesthesiology 1995 Nov;83(5):1021-35 PMID 7486153
  • Implementation of a formal treatment agreement for outpatient management of chronic nonmalignant pain with opioid analgesics. (Burchman SL, Pagel PS) J Pain Symptom Manage 1995 Oct;10(7):556-63 PMID 8537698
  • Zatebradine, a specific bradycardic agent, alters the hemodynamic and left ventricular mechanical actions of levosimendan, a new myofilament calcium sensitizer, in conscious dogs. (Pagel PS, Harkin CP, Hettrick DA, Warltier DC) J Pharmacol Exp Ther 1995 Oct;275(1):127-35 PMID 7562540
  • Differential effects of isoflurane and halothane on aortic input impedance quantified using a three-element Windkessel model. (Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1995 Aug;83(2):361-73 PMID 7631959
  • Systemic and coronary hemodynamic actions and left ventricular functional effects of levosimendan in conscious dogs. (Harkin CP, Pagel PS, Tessmer JP, Warltier DC) J Cardiovasc Pharmacol 1995 Aug;26(2):179-88 PMID 7475041
  • A complication of internal jugular vein double cannulation. (Lowe D, Pagel PS) Anesth Analg 1995 Jul;81(1):206-7 PMID 7598265
  • Protamine inhibits coronary collateral development in a canine model of repetitive coronary occlusion. (Kersten JR, Pagel PS, Warltier DC) Am J Physiol 1995 Feb;268(2 Pt 2):H720-8 PMID 7532374
  • Dexmedetomidine partially attenuates the sympathetically mediated systemic and coronary hemodynamic effects of cocaine. (Kersten JR, Pagel PS, Hettrick DA, Warltier DC) Anesth Analg 1995 Jan;80(1):114-21 PMID 7802267
  • Perfusion of ischemic myocardium during anesthesia with sevoflurane. (Kersten JR, Brayer AP, Pagel PS, Tessmer JP, Warltier DC) Anesthesiology 1994 Oct;81(4):995-1004 PMID 7943851
  • Levosimendan (OR-1259), a myofilament calcium sensitizer, enhances myocardial contractility but does not alter isovolumic relaxation in conscious and anesthetized dogs. (Pagel PS, Harkin CP, Hettrick DA, Warltier DC) Anesthesiology 1994 Oct;81(4):974-87 PMID 7943849
  • Systemic and coronary hemodynamic effects of repetitive cocaine administration in conscious dogs. (Pagel PS, Tessmer JP, Warltier DC) J Cardiovasc Pharmacol 1994 Sep;24(3):443-53 PMID 7528301
  • Direct negative inotropic and lusitropic effects of sevoflurane. (Harkin CP, Pagel PS, Kersten JR, Hettrick DA, Warltier DC) Anesthesiology 1994 Jul;81(1):156-67 PMID 8042785
  • Left ventricular mechanical consequences of dihydropyridine calcium channel modulation in conscious and anesthetized chronically instrumented dogs. (Pagel PS, Hettrick DA, Warltier DC) Anesthesiology 1994 Jul;81(1):190-208 PMID 7519000
  • Transforming growth factor beta 1 preserves endothelial function after multiple brief coronary artery occlusions and reperfusion. (Kenny D, Coughlan MG, Pagel PS, Kampine JP, Warltier DC) Am Heart J 1994 Jun;127(6):1456-61 PMID 8197968
  • Volatile anesthetics and coronary collateral circulation. (Kersten JR, Hartman JC, Pagel PS, Warltier DC) Adv Pharmacol 1994;31:269-84 PMID 7873418
  • Mechanical consequences of calcium channel modulation during volatile anesthetic-induced left ventricular systolic and diastolic dysfunction. (Pagel PS, Warltier DC) Adv Pharmacol 1994;31:125-43 PMID 7532986
  • Quantitation of volatile anesthetic-induced depression of myocardial contractility using a single beat index derived from maximal ventricular power. (Pagel PS, Nijhawan N, Warltier DC) J Cardiothorac Vasc Anesth 1993 Dec;7(6):688-95 PMID 8305659
  • Left ventricular diastolic function in the normal and diseased heart. Perspectives for the anesthesiologist (2). (Pagel PS, Grossman W, Haering JM, Warltier DC) Anesthesiology 1993 Nov;79(5):1104-20 PMID 8238987
  • Dexmedetomidine alters the hemodynamic effects of desflurane and isoflurane in chronically instrumented dogs. (Kersten J, Pagel PS, Tessmer JP, Roerig DL, Schmeling WT, Warltier DC) Anesthesiology 1993 Nov;79(5):1022-32 PMID 7902030
  • Amrinone enhances myocardial contractility and improves left ventricular diastolic function in conscious and anesthetized chronically instrumented dogs. (Pagel PS, Hettrick DA, Warltier DC) Anesthesiology 1993 Oct;79(4):753-65 PMID 8214755
  • Left ventricular diastolic function in the normal and diseased heart. Perspectives for the anesthesiologist (1). (Pagel PS, Grossman W, Haering JM, Warltier DC) Anesthesiology 1993 Oct;79(4):836-54 PMID 8214764
  • Evaluation of myocardial contractility in the chronically instrumented dog with intact autonomic nervous system function: effects of desflurane and isoflurane. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Acta Anaesthesiol Scand 1993 Feb;37(2):203-10 PMID 8447212
  • Reversal of volatile anesthetic-induced depression of myocardial contractility by extracellular calcium also enhances left ventricular diastolic function. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1993 Jan;78(1):141-54 PMID 8424547
  • Negative inotropic effects of propofol as evaluated by the regional preload recruitable stroke work relationship in chronically instrumented dogs. (Pagel PS, Warltier DC) Anesthesiology 1993 Jan;78(1):100-8 PMID 8424542
  • Nitrous oxide impairs functional recovery of stunned myocardium in barbiturate-anesthetized, acutely instrumented dogs. (Siker D, Pagel PS, Pelc LR, Kampine JP, Schmeling WT, Warltier DC) Anesth Analg 1992 Oct;75(4):539-48 PMID 1530167
  • Cardiovascular and respiratory actions of desflurane: is desflurane different from isoflurane? (Warltier DC, Pagel PS) Anesth Analg 1992 Oct;75(4 Suppl):S17-29; discussion S29-31 PMID 1524236
  • Influence of desflurane, isoflurane and halothane on regional tissue perfusion in dogs. (Hartman JC, Pagel PS, Proctor LT, Kampine JP, Schmeling WT, Warltier DC) Can J Anaesth 1992 Oct;39(8):877-87 PMID 1288912
  • Attenuation of the systemic and coronary hemodynamic effects of cocaine in conscious dogs: propranolol versus labetalol. (Kenny D, Pagel PS, Warltier DC) Basic Res Cardiol 1992 Sep-Oct;87(5):465-77 PMID 1334401
  • Cocaine depresses myocardial contractility and prolongs isovolumetric relaxation in conscious dogs with partial autonomic nervous system blockade. (Pagel PS, Power MW, Kenny D, Warltier DC) J Cardiovasc Pharmacol 1992 Jul;20(1):25-34 PMID 1383628
  • Ketamine depresses myocardial contractility as evaluated by the preload recruitable stroke work relationship in chronically instrumented dogs with autonomic nervous system blockade. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1992 Apr;76(4):564-72 PMID 1550282
  • Alteration of canine left ventricular diastolic function by intravenous anesthetics in vivo. Ketamine and propofol. (Pagel PS, Schmeling WT, Kampine JP, Warltier DC) Anesthesiology 1992 Mar;76(3):419-25 PMID 1539854
  • Alteration of left ventricular diastolic function by desflurane, isoflurane, and halothane in the chronically instrumented dog with autonomic nervous system blockade. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1991 Jun;74(6):1103-14 PMID 2042762
  • Influence of volatile anesthetics on myocardial contractility in vivo: desflurane versus isoflurane. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1991 May;74(5):900-7 PMID 2021208
  • Comparison of the systemic and coronary hemodynamic actions of desflurane, isoflurane, halothane, and enflurane in the chronically instrumented dog. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1991 Mar;74(3):539-51 PMID 2001033
  • Influence of desflurane on regional distribution of coronary blood flow in a chronically instrumented canine model of multivessel coronary artery obstruction. (Hartman JC, Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesth Analg 1991 Mar;72(3):289-99 PMID 1994756
  • Effects of nitrous oxide on myocardial contractility as evaluated by the preload recruitable stroke work relationship in chronically instrumented dogs. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1990 Dec;73(6):1148-57 PMID 2147368
  • Comparison of end-systolic pressure-length relations and preload recruitable stroke work as indices of myocardial contractility in the conscious and anesthetized, chronically instrumented dog. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1990 Aug;73(2):278-90 PMID 2382851