Medical College of Wisconsin
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Qing Miao PhD

Qing Miao PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Surgery
Division: Pediatric Surgery

Member of the MCW Cancer Center


Publications

  • Expression of NgBR is highly associated with estrogen receptor alpha and survivin in breast cancer. (Wang B, Zhao B, North P, Kong A, Huang J, Miao QR) PLoS One 2013;8(11):e78083 PMID 24223763
  • Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR. (Kilari S, Remadevi I, Zhao B, Pan J, Miao R, Ramchandran R, North PE, You M, Rahimi N, Wilkinson GA) J Biol Chem 2013 Apr 12;288(15):10265-74 PMID 23393131
  • Nogo-B receptor is essential for angiogenesis in zebrafish via Akt pathway. (Zhao B, Chun C, Liu Z, Horswill MA, Pramanik K, Wilkinson GA, Ramchandran R, Miao RQ) Blood 2010 Dec 9;116(24):5423-33 PMID 20813898
  • Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity. (Verma A, Bhattacharya R, Remadevi I, Li K, Pramanik K, Samant GV, Horswill M, Chun CZ, Zhao B, Wang E, Miao RQ, Mukhopadhyay D, Ramchandran R, Wilkinson GA) Blood 2010 Jun 3;115(22):4614-22 PMID 20086248
  • A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo. (Li K, Blum Y, Verma A, Liu Z, Pramanik K, Leigh NR, Chun CZ, Samant GV, Zhao B, Garnaas MK, Horswill MA, Stanhope SA, North PE, Miao RQ, Wilkinson GA, Affolter M, Ramchandran R) Blood 2010 Jan 7;115(1):133-9 PMID 19880500
  • Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking. (Harrison KD, Miao RQ, Fernandez-Hernándo C, Suárez Y, Dávalos A, Sessa WC) Cell Metab 2009 Sep;10(3):208-18 PMID 19723497
  • Approaches for studying angiogenesis-related signal transduction. (Derakhshan B, Harrison KD, Miao QR, Sessa WC) Methods Enzymol 2008;443:1-23 PMID 18772008
  • The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. (Facchinetti V, Ouyang W, Wei H, Soto N, Lazorchak A, Gould C, Lowry C, Newton AC, Mao Y, Miao RQ, Sessa WC, Qin J, Zhang P, Su B, Jacinto E) EMBO J 2008 Jul 23;27(14):1932-43 PMID 18566586
  • Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. (Fernández-Hernando C, Ackah E, Yu J, Suárez Y, Murata T, Iwakiri Y, Prendergast J, Miao RQ, Birnbaum MJ, Sessa WC) Cell Metab 2007 Dec;6(6):446-57 PMID 18054314
  • Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells. (Miao RQ, Fontana J, Fulton D, Lin MI, Harrison KD, Sessa WC) Arterioscler Thromb Vasc Biol 2008 Jan;28(1):105-11 PMID 17975117
  • Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells. (Miao RQ, Gao Y, Harrison KD, Prendergast J, Acevedo LM, Yu J, Hu F, Strittmatter SM, Sessa WC) Proc Natl Acad Sci U S A 2006 Jul 18;103(29):10997-1002 PMID 16835300
  • Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis. (Zhang R, Luo D, Miao R, Bai L, Ge Q, Sessa WC, Min W) Oncogene 2005 Jun 2;24(24):3954-63 PMID 15782121
  • A new role for Nogo as a regulator of vascular remodeling. (Acevedo L, Yu J, Erdjument-Bromage H, Miao RQ, Kim JE, Fulton D, Tempst P, Strittmatter SM, Sessa WC) Nat Med 2004 Apr;10(4):382-8 PMID 15034570
  • Structural elements of kallistatin required for inhibition of angiogenesis. (Miao RQ, Chen V, Chao L, Chao J) Am J Physiol Cell Physiol 2003 Jun;284(6):C1604-13 PMID 12734113
  • Kallistatin is a new inhibitor of angiogenesis and tumor growth. (Miao RQ, Agata J, Chao L, Chao J) Blood 2002 Nov 1;100(9):3245-52 PMID 12384424
  • Novel roles of kallistatin, a specific tissue kallikrein inhibitor, in vascular remodeling. (Chao J, Miao RQ, Chen V, Chen LM, Chao L) Biol Chem 2001 Jan;382(1):15-21 PMID 11258665
  • Bradykinin B(1) receptor mediates inhibition of neointima formation in rat artery after balloon angioplasty. (Agata J, Miao RQ, Yayama K, Chao L, Chao J) Hypertension 2000 Sep;36(3):364-70 PMID 10988266
  • Kallistatin stimulates vascular smooth muscle cell proliferation and migration in vitro and neointima formation in balloon-injured rat artery. (Miao RQ, Murakami H, Song Q, Chao L, Chao J) Circ Res 2000 Mar 3;86(4):418-24 PMID 10700446
  • Adenovirus-mediated kallikrein gene transfer inhibits neointima formation via increased production of nitric oxide in rat artery. (Murakami H, Miao RQ, Chao L, Chao J) Immunopharmacology 1999 Oct 15;44(1-2):137-43 PMID 10604537
  • Kallikrein gene delivery inhibits vascular smooth muscle cell growth and neointima formation in the rat artery after balloon angioplasty. (Murakami H, Yayama K, Miao RQ, Wang C, Chao L, Chao J) Hypertension 1999 Aug;34(2):164-70 PMID 10454435
  • Grants and Awards

  • Role of NgBR in endothelial cell function and angiogenesis (#9207119 09/01/2011 - 07/31/2016) Sponsor: NIH Heart Lung and Blood Institute
  • Role of Nogo-B Receptor (NgBR) in Promoting Ras Translocation and Angiogenesis (#9207841 01/01/2013 - 12/31/2013) Sponsor: American Heart Association - Midwest Affiliate
  • Roles of Nogo-B Receptor (NgBR) in Breast Cancer Initiation and Progression (#9306377 06/01/2013 - 05/31/2015) Sponsor: Cancer Center
  • American Cancer Society Institutional Research Grant (#9206663 01/01/2011 - 04/30/2015) PI of Roles of Nogo-B and Nogo-B receptor (NgBR) in tumor angiogenesis (#2206876)
  • American Cancer Society Institutional Research Grant (#9206663 01/01/2011 - 04/30/2015) PI of Roles of Nogo-B and Nogo-B receptor (NgBR) in tumor angiogenesis (#2206876)