Medical College of Wisconsin
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Robert Love MD

Robert Love MD

Chief, Professor

Institution: Medical College of Wisconsin
Department: Surgery
Division: Cardiothoracic
Program: Cardiothoracic Surgery


Publications

  • Proteasomes in lungs from organ donors and patients with end-stage pulmonary diseases. (Baker TA, Bach HH 4th, Gamelli RL, Love RB, Majetschak M) Physiol Res 2014;63(3):311-9 PMID 24564596
  • Clinical neurology in lung transplantation. (Wigfield CH, Love RB) Handb Clin Neurol 2014;121:1237-43 PMID 24365415
  • Membranous atresia of anomalous left coronary artery originating from the pulmonary artery presenting as an intravascular tumor. (Wyler von Ballmoos MC, Bartz P, Love RB, Woods RK) J Thorac Cardiovasc Surg 2014 Mar;147(3):e13-4 PMID 24246547
  • Role of complement activation in obliterative bronchiolitis post-lung transplantation. (Suzuki H, Lasbury ME, Fan L, Vittal R, Mickler EA, Benson HL, Shilling R, Wu Q, Weber DJ, Wagner SR, Lasaro M, Devore D, Wang Y, Sandusky GE, Lipking K, Pandya P, Reynolds J, Love R, Wozniak T, Gu H, Brown KM, Wilkes DS) J Immunol 2013 Oct 15;191(8):4431-9 PMID 24043901
  • Pepsin concentrations are elevated in the bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis after lung transplantation. (Davis CS, Mendez BM, Flint DV, Pelletiere K, Lowery E, Ramirez L, Love RB, Kovacs EJ, Fisichella PM) J Surg Res 2013 Dec;185(2):e101-8 PMID 23845868
  • An official American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death. (Gries CJ, White DB, Truog RD, Dubois J, Cosio CC, Dhanani S, Chan KM, Corris P, Dark J, Fulda G, Glazier AK, Higgins R, Love R, Mason DP, Nakagawa TA, Shapiro R, Shemie S, Tracy MF, Travaline JM, Valapour M, West L, Zaas D, Halpern SD, American Thoracic Society Health Policy Committee) Am J Respir Crit Care Med 2013 Jul 1;188(1):103-9 PMID 23815722
  • Positioning ganglioside D3 as an immunotherapeutic target in lymphangioleiomyomatosis. (Gilbert ER, Eby JM, Hammer AM, Klarquist J, Christensen DG, Barfuss AJ, Boissy RE, Picken MM, Love RB, Dilling DF, Le Poole IC) Am J Pathol 2013 Jul;183(1):226-34 PMID 23665200
  • Decreased incidence of cytomegalovirus infection with sirolimus in a post hoc randomized, multicenter study in lung transplantation. (Ghassemieh B, Ahya VN, Baz MA, Valentine VG, Arcasoy SM, Love RB, Seethamraju H, Alex CG, Bag R, DeOliveira NC, Vigneswaran WT, Charbeneau J, Garrity ER, Bhorade SM) J Heart Lung Transplant 2013 Jul;32(7):701-6 PMID 23664526
  • Potential of targeting TGF-β for organ transplant patients. (Iwashima M, Love R) Future Med Chem 2013 Mar;5(3):281-9 PMID 23464518
  • Interobserver variability in grading transbronchial lung biopsy specimens after lung transplantation. (Bhorade SM, Husain AN, Liao C, Li LC, Ahya VN, Baz MA, Valentine VG, Love RB, Seethamraju H, Alex CG, Bag R, DeOliveira NC, Vigneswaran WT, Garrity ER, Arcasoy SM) Chest 2013 Jun;143(6):1717-24 PMID 23370547
  • Successful emergent lung transplantation after remote ex vivo perfusion optimization and transportation of donor lungs. (Wigfield CH, Cypel M, Yeung J, Waddell T, Alex C, Johnson C, Keshavjee S, Love RB) Am J Transplant 2012 Oct;12(10):2838-44 PMID 23009140
  • Perspectives on lung transplantation and donation-after-determination-of-cardiac-death donors. (Love RB) Am J Transplant 2012 Sep;12(9):2271-2 PMID 22925184
  • Cellular basis of tissue regeneration by omentum. (Shah S, Lowery E, Braun RK, Martin A, Huang N, Medina M, Sethupathi P, Seki Y, Takami M, Byrne K, Wigfield C, Love RB, Iwashima M) PLoS One 2012;7(6):e38368 PMID 22701632
  • Pin1 protein regulates Smad protein signaling and pulmonary fibrosis. (Shen ZJ, Braun RK, Hu J, Xie Q, Chu H, Love RB, Stodola LA, Rosenthal LA, Szakaly RJ, Sorkness RL, Malter JS) J Biol Chem 2012 Jul 6;287(28):23294-305 PMID 22613712
  • Pulmonary immune changes early after laparoscopic antireflux surgery in lung transplant patients with gastroesophageal reflux disease. (Fisichella PM, Davis CS, Lowery E, Pittman M, Gagermeier J, Love RB, Kovacs EJ) J Surg Res 2012 Oct;177(2):e65-73 PMID 22537841
  • TGF-β converts apoptotic stimuli into the signal for Th9 differentiation. (Takami M, Love RB, Iwashima M) J Immunol 2012 May 1;188(9):4369-75 PMID 22461692
  • Low vitamin D levels are associated with increased rejection and infections after lung transplantation. (Lowery EM, Bemiss B, Cascino T, Durazo-Arvizu RA, Forsythe SM, Alex C, Laghi F, Love RB, Camacho P) J Heart Lung Transplant 2012 Jul;31(7):700-7 PMID 22386448
  • The prevalence and extent of gastroesophageal reflux disease correlates to the type of lung transplantation. (Fisichella PM, Davis CS, Shankaran V, Gagermeier J, Dilling D, Alex CG, Kovacs EJ, Joehl RJ, Love RB) Surg Laparosc Endosc Percutan Tech 2012 Feb;22(1):46-51 PMID 22318059
  • Donation after cardiac death: a 29-year experience. (Bellingham JM, Santhanakrishnan C, Neidlinger N, Wai P, Kim J, Niederhaus S, Leverson GE, Fernandez LA, Foley DP, Mezrich JD, Odorico JS, Love RB, De Oliveira N, Sollinger HW, D'Alessandro AM) Surgery 2011 Oct;150(4):692-702 PMID 22000181
  • The protective role of laparoscopic antireflux surgery against aspiration of pepsin after lung transplantation. (Fisichella PM, Davis CS, Lundberg PW, Lowery E, Burnham EL, Alex CG, Ramirez L, Pelletiere K, Love RB, Kuo PC, Kovacs EJ) Surgery 2011 Oct;150(4):598-606 PMID 22000170
  • Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy. (Brueggemann LI, Kakad PP, Love RB, Solway J, Dowell ML, Cribbs LL, Byron KL) Am J Physiol Lung Cell Mol Physiol 2012 Jan 1;302(1):L120-32 PMID 21964407
  • A current viewpoint of lymphangioleiomyomatosis supporting immunotherapeutic treatment options. (Dilling DF, Gilbert ER, Picken MM, Eby JM, Love RB, Le Poole IC) Am J Respir Cell Mol Biol 2012 Jan;46(1):1-5 PMID 21940815
  • Donation after cardiac death lung transplantation outcomes. (Wigfield CH, Love RB) Curr Opin Organ Transplant 2011 Oct;16(5):462-8 PMID 21897244
  • Laparoscopic antireflux surgery for gastroesophageal reflux disease after lung transplantation. (Fisichella PM, Davis CS, Gagermeier J, Dilling D, Alex CG, Dorfmeister JA, Kovacs EJ, Love RB, Gamelli RL) J Surg Res 2011 Oct;170(2):e279-86 PMID 21816422
  • Increased risk of venous thromboembolism with a sirolimus-based immunosuppression regimen in lung transplantation. (Ahya VN, McShane PJ, Baz MA, Valentine VG, Arcasoy SM, Love RB, Seethamraju H, Garrity E, Alex CG, Bag R, DeOliveira NC, Vigneswaran WT, Charbeneau J, Krishnan JA, Durazo-Arvizu R, Norwick L, Bhorade S) J Heart Lung Transplant 2011 Feb;30(2):175-81 PMID 20947384
  • Comparison of sirolimus with azathioprine in a tacrolimus-based immunosuppressive regimen in lung transplantation. (Bhorade S, Ahya VN, Baz MA, Valentine VG, Arcasoy SM, Love RB, Seethamraju H, Alex CG, Bag R, Deoliveira NC, Husain A, Vigneswaran WT, Charbeneau J, Krishnan JA, Durazo-Arvizu R, Norwick L, Garrity E) Am J Respir Crit Care Med 2011 Feb 1;183(3):379-87 PMID 20833822
  • Gastroesophageal reflux disease after lung transplantation: pathophysiology and implications for treatment. (Davis CS, Shankaran V, Kovacs EJ, Gagermeier J, Dilling D, Alex CG, Love RB, Sinacore J, Fisichella PM) Surgery 2010 Oct;148(4):737-44; discussion 744-5 PMID 20727564
  • Inhibition of bleomycin-induced pulmonary fibrosis through pre-treatment with collagen type V. (Braun RK, Martin A, Shah S, Iwashima M, Medina M, Byrne K, Sethupathi P, Wigfield CH, Brand DD, Love RB) J Heart Lung Transplant 2010 Aug;29(8):873-80 PMID 20471860
  • Lung transplantation with donation after cardiac death donors: long-term follow-up in a single center. (De Oliveira NC, Osaki S, Maloney JD, Meyer KC, Kohmoto T, D'Alessandro AM, Love RB) J Thorac Cardiovasc Surg 2010 May;139(5):1306-15 PMID 20412963
  • A review of the potential applications and controversies of non-invasive testing for biomarkers of aspiration in the lung transplant population. (Davis CS, Gagermeier J, Dilling D, Alex C, Lowery E, Kovacs EJ, Love RB, Fisichella PM) Clin Transplant 2010 May-Jun;24(3):E54-61 PMID 20331688
  • Transfer of tolerance to collagen type V suppresses T-helper-cell-17 lymphocyte-mediated acute lung transplant rejection. (Braun RK, Molitor-Dart M, Wigfield C, Xiang Z, Fain SB, Jankowska-Gan E, Seroogy CM, Burlingham WJ, Wilkes DS, Brand DD, Torrealba J, Love RB) Transplantation 2009 Dec 27;88(12):1341-8 PMID 20029330
  • Melanoma-associated antigen expression in lymphangioleiomyomatosis renders tumor cells susceptible to cytotoxic T cells. (Klarquist J, Barfuss A, Kandala S, Reust MJ, Braun RK, Hu J, Dilling DF, McKee MD, Boissy RE, Love RB, Nishimura MI, Le Poole IC) Am J Pathol 2009 Dec;175(6):2463-72 PMID 19893037
  • Effect of annual influenza immunization on antibody response in lung transplant patients. (Dopp JM, Wiegert NA, Moran JJ, Francois ML, Radford KL, Thomas H, Love RB, Hayney MS) Prog Transplant 2009 Jun;19(2):153-9 PMID 19588665
  • IL-17 producing gammadelta T cells are required for a controlled inflammatory response after bleomycin-induced lung injury. (Braun RK, Ferrick C, Neubauer P, Sjoding M, Sterner-Kock A, Kock M, Putney L, Ferrick DA, Hyde DM, Love RB) Inflammation 2008 Jun;31(3):167-79 PMID 18338242
  • Th-17, monokines, collagen type V, and primary graft dysfunction in lung transplantation. (Bobadilla JL, Love RB, Jankowska-Gan E, Xu Q, Haynes LD, Braun RK, Hayney MS, Munoz del Rio A, Meyer K, Greenspan DS, Torrealba J, Heidler KM, Cummings OW, Iwata T, Brand D, Presson R, Burlingham WJ, Wilkes DS) Am J Respir Crit Care Med 2008 Mar 15;177(6):660-8 PMID 18174545
  • IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants. (Burlingham WJ, Love RB, Jankowska-Gan E, Haynes LD, Xu Q, Bobadilla JL, Meyer KC, Hayney MS, Braun RK, Greenspan DS, Gopalakrishnan B, Cai J, Brand DD, Yoshida S, Cummings OW, Wilkes DS) J Clin Invest 2007 Nov;117(11):3498-506 PMID 17965778
  • T-cell responses to hepatitis B surface antigen in lung transplant recipients. (Hayney MS, Wiegert NA, Pelsue FL, Fohl RM, Jankowska-Gan E, Love RB, Burlingham WJ) Pharmacotherapy 2007 Sep;27(9):1248-52 PMID 17723078
  • Prevention of acute rejection and allograft vasculopathy by everolimus in cardiac transplants recipients: a 24-month analysis. (Viganò M, Tuzcu M, Benza R, Boissonnat P, Haverich A, Hill J, Laufer G, Love R, Parameshwar J, Pulpón LA, Renlund D, Abeywickrama K, Cretin N, Starling RC, Eisen HJ, RAD B253 Study Group) J Heart Lung Transplant 2007 Jun;26(6):584-92 PMID 17543781
  • Lung transplantation for cystic fibrosis: current concepts and one center's experience. (Spahr JE, Love RB, Francois M, Radford K, Meyer KC) J Cyst Fibros 2007 Sep;6(5):334-50 PMID 17418647
  • Early institution of extracorporeal membrane oxygenation for primary graft dysfunction after lung transplantation improves outcome. (Wigfield CH, Lindsey JD, Steffens TG, Edwards NM, Love RB) J Heart Lung Transplant 2007 Apr;26(4):331-8 PMID 17403473
  • Pin1 modulates the type 1 immune response. (Esnault S, Braun RK, Shen ZJ, Xiang Z, Heninger E, Love RB, Sandor M, Malter JS) PLoS One 2007;2(2):e226 PMID 17311089
  • Impact of donor and recipient factors on allograft survival in lung transplantation: A single-center analysis. (Lindsey JD, Wigfield CH, Nath DS, Anderson JE, Leverson GE, Love RB) Transplant Proc 2006 Dec;38(10):3685-8 PMID 17175367
  • Is extreme obesity a risk factor for cardiac surgery? An analysis of patients with a BMI > or = 40. (Wigfield CH, Lindsey JD, Muñoz A, Chopra PS, Edwards NM, Love RB) Eur J Cardiothorac Surg 2006 Apr;29(4):434-40 PMID 16504529
  • Operative treatment of the painful sternoclavicular joint: a new technique using interpositional arthroplasty. (Meis RC, Love RB, Keene JS, Orwin JF) J Shoulder Elbow Surg 2006 Jan-Feb;15(1):60-6 PMID 16414470
  • Daclizumab to prevent rejection after cardiac transplantation. (Hershberger RE, Starling RC, Eisen HJ, Bergh CH, Kormos RL, Love RB, Van Bakel A, Gordon RD, Popat R, Cockey L, Mamelok RD) N Engl J Med 2005 Jun 30;352(26):2705-13 PMID 15987919
  • CMV-infected allogeneic endothelial cells initiate responder and bystander donor HLA class I release via the metalloproteinase cleavage pathway. (Haynes LD, Waldman WJ, Bushkin Y, Love RB, Burlingham WJ) Hum Immunol 2005 Mar;66(3):211-21 PMID 15784459
  • Influenza vaccine antibody responses in lung transplant recipients. (Hayney MS, Welter DL, Francois M, Reynolds AM, Love RB) Prog Transplant 2004 Dec;14(4):346-51 PMID 15663020
  • Donation after cardiac death: the University of Wisconsin experience. (D'Alessandro AM, Fernandez LA, Chin LT, Shames BD, Turgeon NA, Scott DL, Di Carlo A, Becker YT, Odorico JS, Knechtle SJ, Love RB, Pirsch JD, Becker BN, Musat AI, Kalayoglu M, Sollinger HW) Ann Transplant 2004;9(1):68-71 PMID 15478896
  • High-dose hepatitis B vaccine in patients waiting for lung transplantation. (Hayney MS, Welter DL, Reynolds AM, Francois M, Love RB) Pharmacotherapy 2003 May;23(5):555-60 PMID 12741428
  • Pre-transplant mechanical ventilation and outcome in patients with cystic fibrosis. (Bartz RR, Love RB, Leverson GE, Will LR, Welter DL, Meyer KC) J Heart Lung Transplant 2003 Apr;22(4):433-8 PMID 12681421
  • Aspergillus infection in lung transplant recipients with cystic fibrosis: risk factors and outcomes comparison to other types of transplant recipients. (Helmi M, Love RB, Welter D, Cornwell RD, Meyer KC) Chest 2003 Mar;123(3):800-8 PMID 12628881
  • Interferon-gamma drives the metalloproteinase-dependent cleavage of HLA class I soluble forms from primary human bronchial epithelial cells. (Haynes LD, Bushkin Y, Love RB, Burlingham WJ) Hum Immunol 2002 Oct;63(10):893-901 PMID 12368042
  • Report of the Crystal City meeting to maximize the use of organs recovered from the cadaver donor. (Rosengard BR, Feng S, Alfrey EJ, Zaroff JG, Emond JC, Henry ML, Garrity ER, Roberts JP, Wynn JJ, Metzger RA, Freeman RB, Port FK, Merion RM, Love RB, Busuttil RW, Delmonico FL) Am J Transplant 2002 Sep;2(8):701-11 PMID 12243491
  • Bronchogenic carcinoma after lung transplantation: frequency, clinical characteristics, and imaging findings. (Collins J, Kazerooni EA, Lacomis J, McAdams HP, Leung AN, Shiau M, Semenkovich J, Love RB) Radiology 2002 Jul;224(1):131-8 PMID 12091672
  • Severe Ehrlichia chaffeensis infection in a lung transplant recipient: a review of ehrlichiosis in the immunocompromised patient. (Safdar N, Love RB, Maki DG) Emerg Infect Dis 2002 Mar;8(3):320-3 PMID 11927032
  • Endoscopic repair of bronchial dehiscence after lung transplantation. (Maloney JD, Weigel TL, Love RB) Ann Thorac Surg 2001 Dec;72(6):2109-11 PMID 11789804
  • Neutrophils, unopposed neutrophil elastase, and alpha1-antiprotease defenses following human lung transplantation. (Meyer KC, Nunley DR, Dauber JH, Iacono AT, Keenan RJ, Cornwell RD, Love RB) Am J Respir Crit Care Med 2001 Jul 1;164(1):97-102 PMID 11435246
  • Cell-mediated immunity to collagen V in lung transplant recipients: correlation with collagen V release into BAL fluid. (Wilkes DS, Heidler KM, Yasufuku K, Devito-Haynes L, Jankowska-Gan E, Meyer KC, Love RB, Burlingham WJ) J Heart Lung Transplant 2001 Feb;20(2):167 PMID 11250258
  • Effect of HLA-DR mismatch on lung transplant outcome. (Love RB, Meyer KC, Devito-Haynes LD, Ulschmid S, Leverson GE, Van Der Bij W, De Boer WJ, Hepkema BG, Cornwell RD, Woolley DS, Burlingham WJ) J Heart Lung Transplant 2001 Feb;20(2):177 PMID 11250286
  • Extended lung preservation with UW solution does not adversely affect graft outcome. (Woolley DS, Devito-Haynes LD, Ulschmid S, Leverson G, Welter DL, Hoffmann A, Cornwell RD, Burlingham WJ, Meyer KC, Love RB) J Heart Lung Transplant 2001 Feb;20(2):207 PMID 11250372
  • Soluble donor HLA class I and beta 2m-free heavy chain in serum of lung transplant recipients: steady-state levels and increases in patients with recurrent CMV infection, acute rejection episodes, and poor outcome. (DeVito-Haynes LD, Jankowska-Gan E, Meyer KC, Cornwell RD, Zeevi A, Griffith B, Dauber J, Iacono A, Burlingham WJ, Love RB) Hum Immunol 2000 Dec;61(12):1370-82 PMID 11163095
  • Vascular endothelial growth factor in human lung transplantation. (Meyer KC, Cardoni AL, Xiang Z, Cornwell RD, Love RB) Chest 2001 Jan;119(1):137-43 PMID 11157595
  • Short- and long-term results after lung volume reduction surgery. (Meyer KC, Cornwell RD, Love RB) Curr Opin Pulm Med 2000 Mar;6(2):116-21 PMID 10741770
  • Does University of Wisconsin solution harm the transplanted heart? (Stringham JC, Love RB, Welter D, Canver CC, Mentzer RM Jr) J Heart Lung Transplant 1999 Jun;18(6):587-96 PMID 10395357
  • Grants and Awards

  • Ex Vivo Lung Perfusion Device (#9208238 07/01/2013 - 06/30/2015) Sponsor: Froedtert Hospital Foundation
  • Placenta Perfusion by Pulsatile Pump (#9208151 07/01/2013 - 01/17/2015) Sponsor: Froedtert Hospital Foundation