Medical College of Wisconsin
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Tina W F Yen MD, MS

Tina W F Yen MD, MS

Associate Professor

Institution: Medical College of Wisconsin
Department: Surgery
Division: Surgical Oncology

Member of the Cancer Center


Research Experience

  • Breast Diseases
  • Breast Neoplasms
  • Endocrine Gland Neoplasms
  • Endocrine Surgical Procedures
  • Lymphedema
  • Outcome Assessment (Health Care)
  • Clinical Expertise

  • Adrenal Gland Neoplasms
  • Adrenalectomy
  • Adrenocortical Adenoma
  • Adrenocortical Carcinoma
  • Breast Diseases
  • Breast Neoplasms
  • Hyperparathyroidism, Primary
  • Hyperparathyroidism, Secondary
  • Hyperthyroidism
  • Parathyroid Diseases
  • Parathyroidectomy
  • Thyroid Neoplasms
  • Thyroid Nodule
  • Thyroidectomy
  • Leadership Positions

  • Director, Observational Methods Core Facility, MCW Cancer Center Program in Cancer Prevention, Control and Population Sciences
  • Service Chief, Breast and Endocrine Surgery, Froedtert Hospital
  • Publications

  • An algorithm to identify the development of lymphedema after breast cancer treatment. (Yen TW, Laud PW, Sparapani RA, Li J, Nattinger AB) J Cancer Surviv 2014 Sep 4: PMID 25187004
  • A single parathyroid hormone level obtained 4┬áhours after total thyroidectomy predicts the need for postoperative calcium supplementation. (Carr AA, Yen TW, Fareau GG, Cayo AK, Misustin SM, Evans DB, Wang TS) J Am Coll Surg 2014 Oct;219(4):757-64 PMID 25053220
  • Quality of life among a population-based cohort of older patients with breast cancer. (Neuner JM, Zokoe N, McGinley EL, Pezzin LE, Yen TW, Schapira MM, Nattinger AB) Breast 2014 Oct;23(5):609-16 PMID 25034932
  • Surgeon specialization and use of sentinel lymph node biopsy for breast cancer. (Yen TW, Laud PW, Sparapani RA, Nattinger AB) JAMA Surg 2014 Feb;149(2):185-92 PMID 24369337
  • Cost analysis of thyroid lobectomy and intraoperative frozen section versus total thyroidectomy in patients with a cytologic diagnosis of "suspicious for papillary thyroid cancer". (Leiker AJ, Yen TW, Cheung K, Evans DB, Wang TS) Surgery 2013 Dec;154(6):1307-13; discussion 1313-4 PMID 24238049
  • The utility of routine preoperative cervical ultrasonography in patients undergoing thyroidectomy for differentiated thyroid cancer. (O'Connell K, Yen TW, Quiroz F, Evans DB, Wang TS) Surgery 2013 Oct;154(4):697-701; discussion 701-3 PMID 24011674
  • Diagnosis and treatment of lymphedema after breast cancer: a population-based study. (Sayko O, Pezzin LE, Yen TW, Nattinger AB) PM R 2013 Nov;5(11):915-23 PMID 23684778
  • Factors that influence parathyroid hormone half-life: determining if new intraoperative criteria are needed. (Leiker AJ, Yen TW, Eastwood DC, Doffek KM, Szabo A, Evans DB, Wang TS) JAMA Surg 2013 Jul;148(7):602-6 PMID 23677330
  • Focused parathyroidectomy with intraoperative parathyroid hormone monitoring in patients with lithium-associated primary hyperparathyroidism. (Wade TJ, Yen TW, Amin AL, Evans DB, Wilson SD, Wang TS) Surgery 2013 May;153(5):718-22 PMID 23352236
  • Is previous same quadrant surgery a contraindication to laparoscopic adrenalectomy? (Mazeh H, Froyshteter AB, Wang TS, Amin AL, Evans DB, Sippel RS, Chen H, Yen TW) Surgery 2012 Dec;152(6):1211-7 PMID 23068085
  • Predicting the need for calcium and calcitriol supplementation after total thyroidectomy: results of a prospective, randomized study. (Cayo AK, Yen TW, Misustin SM, Wall K, Wilson SD, Evans DB, Wang TS) Surgery 2012 Dec;152(6):1059-67 PMID 23068088
  • Persistent elevation in serum parathyroid hormone levels in normocalcemic patients after parathyroidectomy: does it matter? (Carsello CB, Yen TW, Wang TS) Surgery 2012 Oct;152(4):575-81; discussion 581-3 PMID 23021134
  • Effect of prophylactic central compartment neck dissection on serum thyroglobulin and recommendations for adjuvant radioactive iodine in patients with differentiated thyroid cancer. (Wang TS, Evans DB, Fareau GG, Carroll T, Yen TW) Ann Surg Oncol 2012 Dec;19(13):4217-22 PMID 23010732
  • Surgical management of normocalcemic primary hyperparathyroidism. (Wade TJ, Yen TW, Amin AL, Wang TS) World J Surg 2012 Apr;36(4):761-6 PMID 22286968
  • Nonlocalizing imaging studies for hyperparathyroidism: where to explore first? (Amin AL, Wang TS, Wade TJ, Quiroz FA, Hellman RS, Evans DB, Yen TW) J Am Coll Surg 2011 Dec;213(6):793-9 PMID 22014659
  • Primary hyperparathyroidism with a history of head and neck irradiation: the consequences of associated thyroid tumors. (Wilson SD, Doffek KM, Wang TS, Krzywda EA, Evans DB, Yen TW) Surgery 2011 Oct;150(4):869-77 PMID 22000202
  • Socioeconomic and racial differences in treatment for breast cancer at a low-volume hospital. (Kong AL, Yen TW, Pezzin LE, Miao H, Sparapani RA, Laud PW, Nattinger AB) Ann Surg Oncol 2011 Oct;18(11):3220-7 PMID 21861226
  • Normal PTH levels in primary hyperparathyroidism: still the same disease? (Amin AL, Wang TS, Wade TJ, Yen TW) Ann Surg Oncol 2011 Nov;18(12):3437-42 PMID 21537864
  • Genetic testing for BRCA mutations can save lives. (Yen TW) Arch Surg 2011 Apr;146(4):479-80 PMID 21502459
  • Fracture risk and adjuvant hormonal therapy among a population-based cohort of older female breast cancer patients. (Neuner JM, Yen TW, Sparapani RA, Laud PW, Nattinger AB) Osteoporos Int 2011 Nov;22(11):2847-55 PMID 21170643
  • Subtotal parathyroidectomy for primary hyperparathyroidism. (Yen TW, Wang TS) Endocr Pract 2011 Mar-Apr;17 Suppl 1:7-12 PMID 21134873
  • The value of postoperative parathyroid hormone levels in predicting the need for long-term vitamin D supplementation after total thyroidectomy. (Wang TS, Cayo AK, Wilson SD, Yen TW) Ann Surg Oncol 2011 Mar;18(3):777-81 PMID 20957441
  • Operative failures after parathyroidectomy for hyperparathyroidism: the influence of surgical volume. (Chen H, Wang TS, Yen TW, Doffek K, Krzywda E, Schaefer S, Sippel RS, Wilson SD) Ann Surg 2010 Oct;252(4):691-5 PMID 20881776
  • Socioeconomic factors associated with adjuvant hormone therapy use in older breast cancer survivors. (Yen TW, Czypinski LK, Sparapani RA, Guo C, Laud PW, Pezzin LE, Nattinger AB) Cancer 2011 Jan 15;117(2):398-405 PMID 20824718
  • Elderly breast cancer survivors accurately self-report key treatment information. (Yen TW, Sparapani RA, Guo C, Neuner JM, Laud PW, Nattinger AB) J Am Geriatr Soc 2010 Feb;58(2):410-2 PMID 20370882
  • Do practice patterns reflect practice guidelines? (Yen TW, Evans DB) Ann Surg Oncol 2010 Jun;17(6):1478-80 PMID 20232162
  • A contemporary, population-based study of lymphedema risk factors in older women with breast cancer. (Yen TW, Fan X, Sparapani R, Laud PW, Walker AP, Nattinger AB) Ann Surg Oncol 2009 Apr;16(4):979-88 PMID 19194754
  • The influence of surgery in MEN-1 syndrome: observations over 150 years. (Wilson SD, Krzywda EA, Zhu YR, Yen TW, Wang TS, Sugg SL, Pappas SG) Surgery 2008 Oct;144(4):695-701; discussion 701-2 PMID 18847656
  • Reoperative parathyroidectomy: an algorithm for imaging and monitoring of intraoperative parathyroid hormone levels that results in a successful focused approach. (Yen TW, Wang TS, Doffek KM, Krzywda EA, Wilson SD) Surgery 2008 Oct;144(4):611-9; discussion 619-21 PMID 18847646
  • Impact of randomized clinical trial results in the national comprehensive cancer network on the use of tamoxifen after breast surgery for ductal carcinoma in situ. (Yen TW, Kuerer HM, Ottesen RA, Rouse L, Niland JC, Edge SB, Theriault RL, Weeks JC) J Clin Oncol 2007 Aug 1;25(22):3251-8 PMID 17577019
  • Novel clinical trial designs for treatment of ductal carcinoma in situ of the breast with trastuzumab (herceptin). (Gonzalez RJ, Buzdar AU, Fraser Symmans W, Yen TW, Broglio KR, Lucci A, Esteva FJ, Yin G, Kuerer HM) Breast J 2007 Jan-Feb;13(1):72-5 PMID 17214797
  • The role of parathyroid hormone measurements after surgery for primary hyperparathyroidism. (Yen TW, Wilson SD, Krzywda EA, Sugg SL) Surgery 2006 Oct;140(4):665-72; discussion 672-4 PMID 17011915
  • The role of ultrasound in the surgical management of patients diagnosed with ductal carcinoma in situ of the breast. (Khakpour N, Zager JS, Yen T, Stephens T, Kuerer HM, Singletary ES, Ross MI, Hunt KK, Babiera GV) Breast J 2006 May-Jun;12(3):212-5 PMID 16684318
  • Predictors of invasive breast cancer in patients with an initial diagnosis of ductal carcinoma in situ: a guide to selective use of sentinel lymph node biopsy in management of ductal carcinoma in situ. (Yen TW, Hunt KK, Ross MI, Mirza NQ, Babiera GV, Meric-Bernstam F, Singletary SE, Symmans WF, Giordano SH, Feig BW, Ames FC, Kuerer HM) J Am Coll Surg 2005 Apr;200(4):516-26 PMID 15804465
  • Physician recommendations regarding tamoxifen and patient utilization of tamoxifen after surgery for ductal carcinoma in situ. (Yen TW, Hunt KK, Mirza NQ, Thomas ES, Singletary SE, Babiera GV, Meric-Bernstam F, Buchholz TA, Feig BW, Ross MI, Ames FC, Theriault RL, Kuerer HM) Cancer 2004 Mar 1;100(5):942-9 PMID 14983489
  • Medullary thyroid carcinoma: results of a standardized surgical approach in a contemporary series of 80 consecutive patients. (Yen TW, Shapiro SE, Gagel RF, Sherman SI, Lee JE, Evans DB) Surgery 2003 Dec;134(6):890-9; discussion 899-901 PMID 14668720
  • Intraoperative margin assessment reduces reexcision rates in patients with ductal carcinoma in situ treated with breast-conserving surgery. (Chagpar A, Yen T, Sahin A, Hunt KK, Whitman GJ, Ames FC, Ross MI, Meric-Bernstam F, Babiera GV, Singletary SE, Kuerer HM) Am J Surg 2003 Oct;186(4):371-7 PMID 14553853
  • An axillary recurrence of breast cancer following a negative sentinel lymph node biopsy. (Yen TW, Mann GN, Lawton TJ, Livingston RB, Anderson BO) Breast J 2003 May-Jun;9(3):234-6 PMID 12752634
  • Pericarditis after trauma resulting in delayed cardiac tamponade. (Karmy-Jones R, Yen T, Cornejo C) Ann Thorac Surg 2002 Jul;74(1):239-41 PMID 12118769
  • Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas. (Yen TW, Aardal NP, Bronner MP, Thorning DR, Savard CE, Lee SP, Bell RH Jr) Surgery 2002 Feb;131(2):129-34 PMID 11854689
  • The gastrin receptor promotes pancreatic growth in transgenic mice. (Yen TW, Sandgren EP, Liggitt HD, Palmiter RD, Zhou W, Hinds TR, Grippo PJ, McDonald JM, Robinson LM, Bell RH Jr) Pancreas 2002 Mar;24(2):121-9 PMID 11854616
  • Grants and Awards

  • Alliance For Clinical Trials in Oncology (#9208079 05/01/2013 - 04/30/2015) Sponsor: Brigham and Women's Hospital Inc
  • Variations in Patterns of Breast Cancer Care by Hospital Volume (#9306386 06/01/2013 - 05/31/2014) Sponsor: Cancer Center
  • Prevention of Recurrence in Early-Stage, Node-Positive Breast Cancer with Low to Intermediate HER2 Expression with NeuVax Treatment (#9305852 08/14/2012 - 08/13/2015) Sponsor: Aptiv Solutions
  • Non Profit - Alliance for Clinical Trials in Oncology Services Agreement (#9208145 05/01/2013 - 04/30/2014) Sponsor: Brigham and Women's Hospital Inc
  • Lymphedema Incidence and Risk Factors Among Older Breast Cancer Patients (#9204661 07/01/2007 - 10/31/2012) Sponsor: NIH Cancer Institute
  • A Population-based Study of Sentinel Lymph Node Biopsy Adoption Among Breast Cancer Patients: Does Efficacy (#9207962 04/01/2013 - 03/31/2015) Sponsor: James Ewing Foundation