Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Wai-Meng Kwok PhD

Professor

Institution: Medical College of Wisconsin
Department: Anesthesiology
Division: Research


Publications

  • Accelerated inactivation of cardiac L-type calcium channels triggered by anaesthetic-induced preconditioning. (Tampo A, Hogan CS, Sedlic F, Bosnjak ZJ, Kwok WM) Br J Pharmacol 2009 Feb;156(3):432-43 PMID 19154423
  • The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-3'-aminoadenosine-5'-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel. (Wan TC, Ge ZD, Tampo A, Mio Y, Bienengraeber MW, Tracey WR, Gross GJ, Kwok WM, Auchampach JA) J Pharmacol Exp Ther 2008 Jan;324(1):234-43 PMID 17906066
  • Isoflurane activates human cardiac mitochondrial adenosine triphosphate-sensitive K+ channels reconstituted in lipid bilayers. (Jiang MT, Nakae Y, Ljubkovic M, Kwok WM, Stowe DF, Bosnjak ZJ) Anesth Analg 2007 Oct;105(4):926-32, table of contents PMID 17898367
  • Opposing effects of spinal nerve ligation on calcium-activated potassium currents in axotomized and adjacent mammalian primary afferent neurons. (Sarantopoulos CD, McCallum JB, Rigaud M, Fuchs A, Kwok WM, Hogan QH) Brain Res 2007 Feb 9;1132(1):84-99 PMID 17184741
  • Painful peripheral nerve injury decreases calcium current in axotomized sensory neurons. (McCallum JB, Kwok WM, Sapunar D, Fuchs A, Hogan QH) Anesthesiology 2006 Jul;105(1):160-8 PMID 16810008
  • Characterization of human cardiac mitochondrial ATP-sensitive potassium channel and its regulation by phorbol ester in vitro. (Jiang MT, Ljubkovic M, Nakae Y, Shi Y, Kwok WM, Stowe DF, Bosnjak ZJ) Am J Physiol Heart Circ Physiol 2006 May;290(5):H1770-6 PMID 16361367
  • The interaction of isoflurane and protein kinase C-activators on sarcolemmal KATP channels. (Turner LA, Fujimoto K, Suzuki A, Stadnicka A, Bosnjak ZJ, Kwok WM) Anesth Analg 2005 Jun;100(6):1680-6 PMID 15920195
  • Beta-escin diminishes voltage-gated calcium current rundown in perforated patch-clamp recordings from rat primary afferent neurons. (Sarantopoulos C, McCallum JB, Kwok WM, Hogan Q) J Neurosci Methods 2004 Oct 15;139(1):61-8 PMID 15351522
  • Preconditioning of the myocardium by volatile anesthetics. (Kwok WM, Aizawa K) Curr Med Chem Cardiovasc Hematol Agents 2004 Jul;2(3):249-55 PMID 15320790
  • Protein kinase C-epsilon primes the cardiac sarcolemmal adenosine triphosphate-sensitive potassium channel to modulation by isoflurane. (Aizawa K, Turner LA, Weihrauch D, Bosnjak ZJ, Kwok WM) Anesthesiology 2004 Aug;101(2):381-9 PMID 15277921
  • Contribution of reactive oxygen species to isoflurane-induced sensitization of cardiac sarcolemmal adenosine triphosphate-sensitive potassium channel to pinacidil. (An J, Stadnicka A, Kwok WM, Bosnjak ZJ) Anesthesiology 2004 Mar;100(3):575-80 PMID 15108971
  • ATP-sensitive potassium channels in rat primary afferent neurons: the effect of neuropathic injury and gabapentin. (Sarantopoulos C, McCallum B, Sapunar D, Kwok WM, Hogan Q) Neurosci Lett 2003 Jun 12;343(3):185-9 PMID 12770693
  • The effects of isoflurane on the cardiac slowly activating delayed-rectifier potassium channel in Guinea pig ventricular myocytes. (Suzuki A, Bosnjak ZJ, Kwok WM) Anesth Analg 2003 May;96(5):1308-15, table of contents PMID 12707124
  • Isoflurane activates rat mitochondrial ATP-sensitive K+ channels reconstituted in lipid bilayers. (Nakae Y, Kwok WM, Bosnjak ZJ, Jiang MT) Am J Physiol Heart Circ Physiol 2003 May;284(5):H1865-71 PMID 12573994
  • Grants and Awards

  • Volatile Anesthetic Action on Cardiac K Channels (#9203862 09/30/2005 - 08/31/2010) Sponsor: NIH General Medical Sciences
  • Anesthetic-Induced Cardiac Preconditioning (#9202848 05/05/2003 - 04/30/2009) PI of Project III: Cardiac Electrophysiology in Anesthetic-Induced Preconditioning (#2204561)