Medical College of Wisconsin
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William B. Campbell PhD

William B. Campbell PhD

Chairman, Professor

Institution: Medical College of Wisconsin
Department: Pharmacology and Toxicology
Program: Pharmacology

Member of the MCW Cancer Center


Publications

  • 14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates: Carboxylate Modifications. (Falck JR, Koduru SR, Mohapatra S, Manne R, Atcha R, Manthati VL, Capdevila JH, Christian S, Imig JD, Campbell WB) J Med Chem 2014 Aug 28;57(16):6965-72 PMID 25119815
  • A Novel Activity of Microsomal Epoxide Hydrolase: Metabolism of the Endocannabinoid 2-Arachidonoylglycerol. (Nithipatikom K, Endsley MP, Pfeiffer AW, Falck JR, Campbell WB) J Lipid Res 2014 Jun 23: PMID 24958911
  • Regulation of KCa2.3 and endothelium-dependent hyperpolarization (EDH) in the rat middle cerebral artery: the role of lipoxygenase metabolites and isoprostanes. (Gauthier KM, Campbell WB, McNeish AJ) PeerJ 2014;2:e414 PMID 24949235
  • Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition. (Hye Khan MA, Pavlov TS, Christain SV, Neckář J, Staruschenko A, Gauthier KM, Capdevila JH, Falck JR, Campbell WB, Imig JD) Clin Sci (Lond) 2014 Oct;127(7):463-74 PMID 24707975
  • Aldosterone secretagogues increase adrenal blood flow in male rats. (Ansurudeen I, Kopf PG, Gauthier KM, Bornstein SR, Cowley AW Jr, Campbell WB) Endocrinology 2014 Jan;155(1):127-32 PMID 24169551
  • Role of macrophage PPARγ in experimental hypertension. (Kriska T, Cepura C, Gauthier KM, Campbell WB) Am J Physiol Heart Circ Physiol 2014 Jan 1;306(1):H26-32 PMID 24163073
  • Endothelial metabolism of angiotensin II to angiotensin III, not angiotensin (1-7), augments the vasorelaxation response in adrenal cortical arteries. (Kopf PG, Campbell WB) Endocrinology 2013 Dec;154(12):4768-76 PMID 24092640
  • Effect of human 15-lipoxygenase-1 metabolites on vascular function in mouse mesenteric arteries and hearts. (Kriska T, Cepura C, Siangjong L, Wan TC, Auchampach JA, Shaish A, Haratz D, Kumar G, Falck JR, Gauthier KM, Campbell WB) Prostaglandins Other Lipid Mediat 2013 Oct;106:8-15 PMID 23872364
  • ACE inhibition enhances bradykinin relaxations through nitric oxide and B1 receptor activation in bovine coronary arteries. (Gauthier KM, Cepura CJ, Campbell WB) Biol Chem 2013 Sep;394(9):1205-12 PMID 23729620
  • Arachidonic acid-induced dilation in human coronary arterioles: convergence of signaling mechanisms on endothelial TRPV4-mediated Ca2+ entry. (Zheng X, Zinkevich NS, Gebremedhin D, Gauthier KM, Nishijima Y, Fang J, Wilcox DA, Campbell WB, Gutterman DD, Zhang DX) J Am Heart Assoc 2013 Jun;2(3):e000080 PMID 23619744
  • Ecto-5'-nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase. (Ohta M, Toyama K, Gutterman DD, Campbell WB, Lemaître V, Teraoka R, Miura H) Arterioscler Thromb Vasc Biol 2013 Mar;33(3):629-36 PMID 23288168
  • Inducible endothelium-derived hyperpolarizing factor: role of the 15-lipoxygenase-EDHF pathway. (Campbell WB, Gauthier KM) J Cardiovasc Pharmacol 2013 Mar;61(3):176-87 PMID 23249676
  • Angiotensin II and III metabolism and effects on steroid production in the HAC15 human adrenocortical cell line. (Oki K, Kopf PG, Campbell WB, Luis Lam M, Yamazaki T, Gomez-Sanchez CE, Gomez-Sanchez EP) Endocrinology 2013 Jan;154(1):214-21 PMID 23221601
  • Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries. (Siangjong L, Gauthier KM, Pfister SL, Smyth EM, Campbell WB) Am J Physiol Heart Circ Physiol 2013 Feb 1;304(3):H382-92 PMID 23203967
  • Cytochrome P450 1B1 gene disruption minimizes deoxycorticosterone acetate-salt-induced hypertension and associated cardiac dysfunction and renal damage in mice. (Jennings BL, Estes AM, Anderson LJ, Fang XR, Yaghini FA, Fan Z, Gonzalez FJ, Campbell WB, Malik KU) Hypertension 2012 Dec;60(6):1510-6 PMID 23108654
  • Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension. (Kriska T, Cepura C, Magier D, Siangjong L, Gauthier KM, Campbell WB) Am J Physiol Heart Circ Physiol 2012 Jun 1;302(11):H2428-38 PMID 22467300
  • ROCK1 feedback regulation of the upstream small GTPase RhoA. (Tang AT, Campbell WB, Nithipatikom K) Cell Signal 2012 Jul;24(7):1375-80 PMID 22430126
  • 11,12,20-Trihydroxy-eicosa-8(Z)-enoic acid: a selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries. (Bukhari IA, Shah AJ, Gauthier KM, Walsh KA, Koduru SR, Imig JD, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2012 Apr 15;302(8):H1574-83 PMID 22307677
  • Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta. (Aggarwal NT, Gauthier KM, Campbell WB) Vascul Pharmacol 2012 Jan-Feb;56(1-2):106-12 PMID 22197897
  • Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice. (Jennings BL, Anderson LJ, Estes AM, Yaghini FA, Fang XR, Porter J, Gonzalez FJ, Campbell WB, Malik KU) Hypertension 2012 Feb;59(2):348-54 PMID 22184325
  • Involvement of cytochrome P-450 1B1 in renal dysfunction, injury, and inflammation associated with angiotensin II-induced hypertension in rats. (Jennings BL, Anderson LJ, Estes AM, Fang XR, Song CY, Campbell WB, Malik KU) Am J Physiol Renal Physiol 2012 Feb 15;302(4):F408-20 PMID 22088434
  • Cannabinoid receptor type 1 (CB1) activation inhibits small GTPase RhoA activity and regulates motility of prostate carcinoma cells. (Nithipatikom K, Gomez-Granados AD, Tang AT, Pfeiffer AW, Williams CL, Campbell WB) Endocrinology 2012 Jan;153(1):29-41 PMID 22087025
  • Eicosanoids and disease. Introduction. (Spector AA, Campbell WB, Zeldin DC) Prostaglandins Other Lipid Mediat 2011 Nov;96(1-4):1-2 PMID 22004919
  • Soluble epoxide hydrolase contamination of specific catalase preparations inhibits epoxyeicosatrienoic acid vasodilation of rat renal arterioles. (Gauthier KM, Olson L, Harder A, Isbell M, Imig JD, Gutterman DD, Falck JR, Campbell WB) Am J Physiol Renal Physiol 2011 Oct;301(4):F765-72 PMID 21753077
  • 20-Iodo-14,15-epoxyeicosa-8(Z)-enoyl-3-azidophenylsulfonamide: photoaffinity labeling of a 14,15-epoxyeicosatrienoic acid receptor. (Chen Y, Falck JR, Manthati VL, Jat JL, Campbell WB) Biochemistry 2011 May 10;50(18):3840-8 PMID 21469660
  • Role of superoxide and thromboxane receptors in acute angiotensin II-induced vasoconstriction of rabbit vessels. (Pfister SL, Nithipatikom K, Campbell WB) Am J Physiol Heart Circ Physiol 2011 Jun;300(6):H2064-71 PMID 21460202
  • Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries. (Gauthier KM, Goldman DH, Aggarwal NT, Chawengsub Y, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2011 Mar;300(3):H725-35 PMID 21193584
  • Angiotensin II regulates adrenal vascular tone through zona glomerulosa cell-derived EETs and DHETs. (Kopf PG, Gauthier KM, Zhang DX, Falck JR, Campbell WB) Hypertension 2011 Feb;57(2):323-9 PMID 21199991
  • Anti-proliferative effect of a putative endocannabinoid, 2-arachidonylglyceryl ether in prostate carcinoma cells. (Nithipatikom K, Isbell MA, Endsley MP, Woodliff JE, Campbell WB) Prostaglandins Other Lipid Mediat 2011 Feb;94(1-2):34-43 PMID 21167293
  • Vascular pharmacology of epoxyeicosatrienoic acids. (Pfister SL, Gauthier KM, Campbell WB) Adv Pharmacol 2010;60:27-59 PMID 21081214
  • 14,15-Dihydroxy-eicosa-5(Z)-enoic acid selectively inhibits 14,15-epoxyeicosatrienoic acid-induced relaxations in bovine coronary arteries. (Bukhari IA, Gauthier KM, Jagadeesh SG, Sangras B, Falck JR, Campbell WB) J Pharmacol Exp Ther 2011 Jan;336(1):47-55 PMID 20881018
  • Inhibition of carcinoma cell motility by epoxyeicosatrienoic acid (EET) antagonists. (Nithipatikom K, Brody DM, Tang AT, Manthati VL, Falck JR, Williams CL, Campbell WB) Cancer Sci 2010 Dec;101(12):2629-36 PMID 20804500
  • Angiotensin II-induced vascular smooth muscle cell migration and growth are mediated by cytochrome P450 1B1-dependent superoxide generation. (Yaghini FA, Song CY, Lavrentyev EN, Ghafoor HU, Fang XR, Estes AM, Campbell WB, Malik KU) Hypertension 2010 Jun;55(6):1461-7 PMID 20439821
  • Epoxyeicosatrienoic acids and endothelium-dependent responses. (Campbell WB, Fleming I) Pflugers Arch 2010 May;459(6):881-95 PMID 20224870
  • Adrenic acid metabolites as endogenous endothelium-derived and zona glomerulosa-derived hyperpolarizing factors. (Kopf PG, Zhang DX, Gauthier KM, Nithipatikom K, Yi XY, Falck JR, Campbell WB) Hypertension 2010 Feb;55(2):547-54 PMID 20038752
  • 20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site. (Chen Y, Falck JR, Tuniki VR, Campbell WB) J Pharmacol Exp Ther 2009 Dec;331(3):1137-45 PMID 19762546
  • Identification of 13-hydroxy-14,15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries. (Chawengsub Y, Gauthier KM, Nithipatikom K, Hammock BD, Falck JR, Narsimhaswamy D, Campbell WB) J Biol Chem 2009 Nov 6;284(45):31280-90 PMID 19737933
  • 14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition. (Falck JR, Kodela R, Manne R, Atcha KR, Puli N, Dubasi N, Manthati VL, Capdevila JH, Yi XY, Goldman DH, Morisseau C, Hammock BD, Campbell WB) J Med Chem 2009 Aug 27;52(16):5069-75 PMID 19653681
  • Role of arachidonic acid lipoxygenase metabolites in the regulation of vascular tone. (Chawengsub Y, Gauthier KM, Campbell WB) Am J Physiol Heart Circ Physiol 2009 Aug;297(2):H495-507 PMID 19525377
  • Evidence for role of epoxyeicosatrienoic acids in mediating ischemic preconditioning and postconditioning in dog. (Gross GJ, Gauthier KM, Moore J, Campbell WB, Falck JR, Nithipatikom K) Am J Physiol Heart Circ Physiol 2009 Jul;297(1):H47-52 PMID 19448143
  • Chronic hypoxia enhances 15-lipoxygenase-mediated vasorelaxation in rabbit arteries. (Aggarwal NT, Pfister SL, Gauthier KM, Chawengsub Y, Baker JE, Campbell WB) Am J Physiol Heart Circ Physiol 2009 Mar;296(3):H678-88 PMID 19112096
  • Hypercholesterolemia enhances 15-lipoxygenase-mediated vasorelaxation and acetylcholine-induced hypotension. (Aggarwal NT, Pfister SL, Campbell WB) Arterioscler Thromb Vasc Biol 2008 Dec;28(12):2209-15 PMID 18832753
  • Roles of Eicosanoids in Prostate Cancer. (Nithipatikom K, Campbell WB) Future Lipidol 2008 Aug 1;3(4):453-467 PMID 24563660
  • Expression and function of fatty acid amide hydrolase in prostate cancer. (Endsley MP, Thill R, Choudhry I, Williams CL, Kajdacsy-Balla A, Campbell WB, Nithipatikom K) Int J Cancer 2008 Sep 15;123(6):1318-26 PMID 18566995
  • Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide. (Gauthier KM, Zhang DX, Cui L, Nithipatikom K, Campbell WB) Hypertension 2008 Jul;52(1):150-5 PMID 18490519
  • 15-Lipoxygenase metabolites contribute to age-related reduction in acetylcholine-induced hypotension in rabbits. (Aggarwal NT, Gauthier KM, Campbell WB) Am J Physiol Heart Circ Physiol 2008 Jul;295(1):H89-96 PMID 18456739
  • Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. (Gross GJ, Gauthier KM, Moore J, Falck JR, Hammock BD, Campbell WB, Nithipatikom K) Am J Physiol Heart Circ Physiol 2008 Jun;294(6):H2838-44 PMID 18441205
  • Identification and characterization of the unique guanine nucleotide exchange factor, SmgGDS, in vascular smooth muscle cells. (Thill R, Campbell WB, Williams CL) J Cell Biochem 2008 Aug 1;104(5):1760-70 PMID 18348285
  • Structural characterization of monohydroxyeicosatetraenoic acids and dihydroxy- and trihydroxyeicosatrienoic acids by ESI-FTICR. (Cui L, Isbell MA, Chawengsub Y, Falck JR, Campbell WB, Nithipatikom K) J Am Soc Mass Spectrom 2008 Apr;19(4):569-85 PMID 18296063
  • 11(R),12(S),15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid: an endothelium-derived 15-lipoxygenase metabolite that relaxes rabbit aorta. (Gauthier KM, Chawengsub Y, Goldman DH, Conrow RE, Anjaiah S, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2008 Mar;294(3):H1467-72 PMID 18203841
  • Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta. (Chawengsub Y, Aggarwal NT, Nithipatikom K, Gauthier KM, Anjaiah S, Hammock BD, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2008 Mar;294(3):H1348-56 PMID 18192225
  • Endothelial 15-lipoxygenase-1 overexpression increases acetylcholine-induced hypotension and vasorelaxation in rabbits. (Aggarwal NT, Chawengsub Y, Gauthier KM, Viita H, Yla-Herttuala S, Campbell WB) Hypertension 2008 Feb;51(2):246-51 PMID 18180398
  • Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid. (Yang W, Tuniki VR, Anjaiah S, Falck JR, Hillard CJ, Campbell WB) J Pharmacol Exp Ther 2008 Mar;324(3):1019-27 PMID 18171909
  • Roles of epoxyeicosatrienoic acids in vascular regulation and cardiac preconditioning. (Gauthier KM, Yang W, Gross GJ, Campbell WB) J Cardiovasc Pharmacol 2007 Dec;50(6):601-8 PMID 18091575
  • Age-related decrease in 15-lipoxygenase contributes to reduced vasorelaxation in rabbit aorta. (Tang X, Aggarwal N, Holmes BB, Kuhn H, Campbell WB) Am J Physiol Heart Circ Physiol 2008 Feb;294(2):H679-87 PMID 18055513
  • Hydrogen peroxide inhibits cytochrome p450 epoxygenases: interaction between two endothelium-derived hyperpolarizing factors. (Larsen BT, Gutterman DD, Sato A, Toyama K, Campbell WB, Zeldin DC, Manthati VL, Falck JR, Miura H) Circ Res 2008 Jan 4;102(1):59-67 PMID 17975109
  • Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase. (Hillard CJ, Shi L, Tuniki VR, Falck JR, Campbell WB) J Mol Neurosci 2007 Sep;33(1):18-24 PMID 17901541
  • Simultaneous analysis of angiotensin peptides by LC-MS and LC-MS/MS: metabolism by bovine adrenal endothelial cells. (Cui L, Nithipatikom K, Campbell WB) Anal Biochem 2007 Oct 1;369(1):27-33 PMID 17681269
  • Steroid-producing cells regulate arterial tone of adrenal cortical arteries. (Zhang DX, Gauthier KM, Falck JR, Siddam A, Campbell WB) Endocrinology 2007 Aug;148(8):3569-76 PMID 17446179
  • Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism. (Endsley MP, Aggarwal N, Isbell MA, Wheelock CE, Hammock BD, Falck JR, Campbell WB, Nithipatikom K) Int J Cancer 2007 Sep 1;121(5):984-91 PMID 17443494
  • ACh-induced relaxations of rabbit small mesenteric arteries: role of arachidonic acid metabolites and K+. (Zhang DX, Gauthier KM, Chawengsub Y, Campbell WB) Am J Physiol Heart Circ Physiol 2007 Jul;293(1):H152-9 PMID 17337603
  • Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding. (Yang W, Holmes BB, Gopal VR, Kishore RV, Sangras B, Yi XY, Falck JR, Campbell WB) J Pharmacol Exp Ther 2007 Jun;321(3):1023-31 PMID 17327488
  • Epoxygenase eicosanoids: synthesis of tetrahydrofuran-diol metabolites and their vasoactivity. (Falck JR, Reddy LM, Byun K, Campbell WB, Yi XY) Bioorg Med Chem Lett 2007 May 1;17(9):2634-8 PMID 17293113
  • Metabolism of adrenic acid to vasodilatory 1alpha,1beta-dihomo-epoxyeicosatrienoic acids by bovine coronary arteries. (Yi XY, Gauthier KM, Cui L, Nithipatikom K, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2007 May;292(5):H2265-74 PMID 17209008
  • Arachidonic acid metabolites as endothelium-derived hyperpolarizing factors. (Campbell WB, Falck JR) Hypertension 2007 Mar;49(3):590-6 PMID 17200437
  • Beyond vasodilatation: non-vasomotor roles of epoxyeicosatrienoic acids in the cardiovascular system. (Larsen BT, Campbell WB, Gutterman DD) Trends Pharmacol Sci 2007 Jan;28(1):32-8 PMID 17150260
  • Endothelium-derived steroidogenic factor enhances angiotensin II-stimulated aldosterone release by bovine zona glomerulosa cells. (Hanke CJ, Holmes BB, Xu Y, Nithipatikom K, Campbell WB) Endocrinology 2007 Jan;148(1):317-23 PMID 17053027
  • Adenoviral expression of 15-lipoxygenase-1 in rabbit aortic endothelium: role in arachidonic acid-induced relaxation. (Aggarwal NT, Holmes BB, Cui L, Viita H, Yla-Herttuala S, Campbell WB) Am J Physiol Heart Circ Physiol 2007 Feb;292(2):H1033-41 PMID 17040969
  • Reduced expression of 15-lipoxygenase 2 in human head and neck carcinomas. (Wang D, Chen S, Feng Y, Yang Q, Campbell BH, Tang X, Campbell WB) Tumour Biol 2006;27(5):261-73 PMID 16874012
  • Chiral resolution of the epoxyeicosatrienoic acids, arachidonic acid epoxygenase metabolites. (Wei S, Brittin JJ, Falck JR, Anjaiah S, Nithipatikom K, Cui L, Campbell WB, Capdevila JH) Anal Biochem 2006 May 1;352(1):129-34 PMID 16480681
  • A role for heterocellular coupling and EETs in dilation of rat cremaster arteries. (McSherry IN, Sandow SL, Campbell WB, Falck JR, Hill MA, Dora KA) Microcirculation 2006 Mar;13(2):119-30 PMID 16459325
  • Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition. (Larsen BT, Miura H, Hatoum OA, Campbell WB, Hammock BD, Zeldin DC, Falck JR, Gutterman DD) Am J Physiol Heart Circ Physiol 2006 Feb;290(2):H491-9 PMID 16258029
  • Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aorta. (Tang X, Holmes BB, Nithipatikom K, Hillard CJ, Kuhn H, Campbell WB) Arterioscler Thromb Vasc Biol 2006 Jan;26(1):78-84 PMID 16239596
  • Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection. (Nithipatikom K, Endsley MP, Moore JM, Isbell MA, Falck JR, Campbell WB, Gross GJ) Am J Physiol Heart Circ Physiol 2006 Feb;290(2):H500-5 PMID 16214838
  • Regulation of potassium channels in coronary smooth muscle by adenoviral expression of cytochrome P-450 epoxygenase. (Campbell WB, Holmes BB, Falck JR, Capdevila JH, Gauthier KM) Am J Physiol Heart Circ Physiol 2006 Jan;290(1):H64-71 PMID 16143653
  • Novel mechanism of vasodilation in inflammatory bowel disease. (Hatoum OA, Gauthier KM, Binion DG, Miura H, Telford G, Otterson MF, Campbell WB, Gutterman DD) Arterioscler Thromb Vasc Biol 2005 Nov;25(11):2355-61 PMID 16141408
  • Mechanisms of histamine-induced relaxation in bovine small adrenal cortical arteries. (Zhang DX, Gauthier KM, Campbell WB) Am J Physiol Endocrinol Metab 2005 Dec;289(6):E1058-63 PMID 16076876
  • Role of phospholipase C and diacylglyceride lipase pathway in arachidonic acid release and acetylcholine-induced vascular relaxation in rabbit aorta. (Tang X, Edwards EM, Holmes BB, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2006 Jan;290(1):H37-45 PMID 16024567
  • A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. (Nithipatikom K, Endsley MP, Isbell MA, Wheelock CE, Hammock BD, Campbell WB) Biochem Biophys Res Commun 2005 Jul 15;332(4):1028-33 PMID 15919052
  • Induction of human cholesterol 7alpha-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone. (Charoenteeraboon J, Nithipatikom K, Campbell WB, Piyachaturawat P, Wilairat P, Rongnoparut P) Eur J Pharmacol 2005 May 16;515(1-3):43-6 PMID 15896733
  • Bradykinin-induced, endothelium-dependent responses in porcine coronary arteries: involvement of potassium channel activation and epoxyeicosatrienoic acids. (Weston AH, Félétou M, Vanhoutte PM, Falck JR, Campbell WB, Edwards G) Br J Pharmacol 2005 Jul;145(6):775-84 PMID 15895105
  • Angiotensin II dilates bovine adrenal cortical arterioles: role of endothelial nitric oxide. (Gauthier KM, Zhang DX, Edwards EM, Holmes B, Campbell WB) Endocrinology 2005 Aug;146(8):3319-24 PMID 15890772
  • Elevated 12- and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases. (Nithipatikom K, Isbell MA, See WA, Campbell WB) Cancer Lett 2006 Feb 28;233(2):219-25 PMID 15882928
  • Stable 5,6-epoxyeicosatrienoic acid analog relaxes coronary arteries through potassium channel activation. (Yang W, Gauthier KM, Reddy LM, Sangras B, Sharma KK, Nithipatikom K, Falck JR, Campbell WB) Hypertension 2005 Apr;45(4):681-6 PMID 15699458
  • 14,15-epoxyeicosatrienoic acid represents a transferable endothelium-dependent relaxing factor in bovine coronary arteries. (Gauthier KM, Edwards EM, Falck JR, Reddy DS, Campbell WB) Hypertension 2005 Apr;45(4):666-71 PMID 15699460
  • Measurement of steroid synthesis in zona glomerulosa cells by liquid chromatography-electrospray ionization-mass spectrometry: inhibition by nitric oxide. (Nithipatikom K, Holmes BB, Isbell MA, Hanke CJ, Gomez-Sanchez CE, Campbell WB) Anal Biochem 2005 Feb 15;337(2):203-10 PMID 15691500
  • 2-arachidonoylglycerol: a novel inhibitor of androgen-independent prostate cancer cell invasion. (Nithipatikom K, Endsley MP, Isbell MA, Falck JR, Iwamoto Y, Hillard CJ, Campbell WB) Cancer Res 2004 Dec 15;64(24):8826-30 PMID 15604240
  • Cytochrome P450 omega-hydroxylase inhibition reduces infarct size during reperfusion via the sarcolemmal KATP channel. (Gross ER, Nithipatikom K, Hsu AK, Peart JN, Falck JR, Campbell WB, Gross GJ) J Mol Cell Cardiol 2004 Dec;37(6):1245-9 PMID 15572055
  • Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries. (Gauthier KM, Baewer DV, Hittner S, Hillard CJ, Nithipatikom K, Reddy DS, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2005 Mar;288(3):H1344-51 PMID 15528233
  • Endostatin uncouples NO and Ca2+ response to bradykinin through enhanced O2*- production in the intact coronary endothelium. (Zhang AY, Teggatz EG, Zou AP, Campbell WB, Li PL) Am J Physiol Heart Circ Physiol 2005 Feb;288(2):H686-94 PMID 15471985
  • Cyclooxygenase- and lipoxygenase-dependent relaxation to arachidonic acid in rabbit small mesenteric arteries. (Zhang DX, Gauthier KM, Chawengsub Y, Holmes BB, Campbell WB) Am J Physiol Heart Circ Physiol 2005 Jan;288(1):H302-9 PMID 15388505
  • Inhibition of cytochrome P450omega-hydroxylase: a novel endogenous cardioprotective pathway. (Nithipatikom K, Gross ER, Endsley MP, Moore JM, Isbell MA, Falck JR, Campbell WB, Gross GJ) Circ Res 2004 Oct 15;95(8):e65-71 PMID 15388642
  • Asymmetric synthesis of the stereoisomers of 11,12,15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid, a potent endothelium-derived vasodilator. (Falck JR, Barma DK, Mohapatra S, Bandyopadhyay A, Reddy KM, Qi J, Campbell WB) Bioorg Med Chem Lett 2004 Oct 4;14(19):4987-90 PMID 15341965
  • Acetylcholine-induced relaxation and hyperpolarization in small bovine adrenal cortical arteries: role of cytochrome P450 metabolites. (Zhang DX, Gauthier KM, Campbell WB) Endocrinology 2004 Oct;145(10):4532-9 PMID 15231705
  • Chronic administration of nitric oxide reduces angiotensin II receptor type 1 expression and aldosterone synthesis in zona glomerulosa cells. (Nithipatikom K, Holmes BB, McCoy MJ, Hillard CJ, Campbell WB) Am J Physiol Endocrinol Metab 2004 Nov;287(5):E820-7 PMID 15198935
  • Protein methylation activates reconstituted ryanodine receptor-ca release channels from coronary artery myocytes. (Chen YF, Zhang AY, Zou AP, Campbell WB, Li PL) J Vasc Res 2004 May-Jun;41(3):229-40 PMID 15118362
  • Glibenclamide inhibits thromboxane-mediated vasoconstriction by thromboxane receptor blockade. (Pfister SL, Pratt PE, Kurian J, Campbell WB) Vascul Pharmacol 2004 Jan;40(6):285-92 PMID 15063832
  • Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism. (Carrier EJ, Kearn CS, Barkmeier AJ, Breese NM, Yang W, Nithipatikom K, Pfister SL, Campbell WB, Hillard CJ) Mol Pharmacol 2004 Apr;65(4):999-1007 PMID 15044630
  • 14,15-EET analogs: characterization of structural requirements for agonist and antagonist activity in bovine coronary arteries. (Gauthier KM, Falck JR, Reddy LM, Campbell WB) Pharmacol Res 2004 Jun;49(6):515-24 PMID 15026029
  • Production of hydroxyeicosatetraenoic acids and prostaglandins by a novel rat microglial cell line. (Rademacher DJ, Kearn CS, Carrier EJ, Patel S, Delgado MA, Barkmeier A, Klick DE, Breese NM, Pfister SL, Nithipatikom K, Campbell WB, Hillard CJ) J Neuroimmunol 2004 Apr;149(1-2):130-41 PMID 15020073
  • Characterization of vasoconstrictor responses in small bovine adrenal cortical arteries in vitro. (Zhang DX, Gauthier KM, Campbell WB) Endocrinology 2004 Apr;145(4):1571-8 PMID 14726440
  • Epoxy-keto derivative of linoleic acid stimulates aldosterone secretion. (Goodfriend TL, Ball DL, Egan BM, Campbell WB, Nithipatikom K) Hypertension 2004 Feb;43(2):358-63 PMID 14718355
  • Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. (Krötz F, Riexinger T, Buerkle MA, Nithipatikom K, Gloe T, Sohn HY, Campbell WB, Pohl U) Arterioscler Thromb Vasc Biol 2004 Mar;24(3):595-600 PMID 14715644
  • Apamin-sensitive K+ currents mediate arachidonic acid-induced relaxations of rabbit aorta. (Gauthier KM, Spitzbarth N, Edwards EM, Campbell WB) Hypertension 2004 Feb;43(2):413-9 PMID 14691199
  • Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450. (Pfister SL, Spitzbarth N, Zeldin DC, Lafite P, Mansuy D, Campbell WB) Arch Biochem Biophys 2003 Dec 1;420(1):142-52 PMID 14622984
  • 20-hydroxyeicosatetraenoic acid (20-HETE) metabolism in coronary endothelial cells. (Kaduce TL, Fang X, Harmon SD, Oltman CL, Dellsperger KC, Teesch LM, Gopal VR, Falck JR, Campbell WB, Weintraub NL, Spector AA) J Biol Chem 2004 Jan 23;279(4):2648-56 PMID 14612451
  • Characterization and application of Raman labels for confocal Raman microspectroscopic detection of cellular proteins in single cells. (Nithipatikom K, McCoy MJ, Hawi SR, Nakamoto K, Adar F, Campbell WB) Anal Biochem 2003 Nov 15;322(2):198-207 PMID 14596828
  • 14,15-epoxyeicosa-5(Z)-enoic-mSI: a 14,15- and 5,6-EET antagonist in bovine coronary arteries. (Gauthier KM, Jagadeesh SG, Falck JR, Campbell WB) Hypertension 2003 Oct;42(4):555-61 PMID 12953017
  • Interleukin-13 upregulates vasodilatory 15-lipoxygenase eicosanoids in rabbit aorta. (Tang X, Spitzbarth N, Kuhn H, Chaitidis P, Campbell WB) Arterioscler Thromb Vasc Biol 2003 Oct 1;23(10):1768-74 PMID 12947015
  • 11,12,15-Trihydroxyeicosatrienoic acid mediates ACh-induced relaxations in rabbit aorta. (Campbell WB, Spitzbarth N, Gauthier KM, Pfister SL) Am J Physiol Heart Circ Physiol 2003 Dec;285(6):H2648-56 PMID 12907422
  • The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. (Patel S, Wohlfeil ER, Rademacher DJ, Carrier EJ, Perry LJ, Kundu A, Falck JR, Nithipatikom K, Campbell WB, Hillard CJ) Br J Pharmacol 2003 Jul;139(5):1005-13 PMID 12839875
  • Metabolism of 12-hydroperoxyeicosatetraenoic acid to vasodilatory trioxilin C3 by rabbit aorta. (Pfister SL, Spitzbarth N, Nithipatikom K, Falck JR, Campbell WB) Biochim Biophys Acta 2003 Jun 20;1622(1):6-13 PMID 12829255
  • Prologue: kinins and related systems. New life for old discoveries. (Skidgel RA, Alhenc-Gelas F, Campbell WB) Am J Physiol Heart Circ Physiol 2003 Jun;284(6):H1886-91 PMID 12742820
  • Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries. (Zhu D, Medhora M, Campbell WB, Spitzbarth N, Baker JE, Jacobs ER) Circ Res 2003 May 16;92(9):992-1000 PMID 12690037
  • Development of enzyme immunoassays for 5,6-, 8,9-, 11,12-, and 14,15- EETs and the corresponding DHETs. (Sasaki DM, Yuan Y, Gikas K, Reddy M, Falck JR, Nithipatikom K, Campbell WB, Callewaert DM) Adv Exp Med Biol 2002;507:531-6 PMID 12664636
  • Determination of cyclooxygenase and arachidonic acid metabolites in invasive human prostate cancer cells. (Nithipatikom K, Borscheid CL, Kajdacsy-Balla A, Kaul S, Lindholm PF, Pytynia KB, Campbell WB) Adv Exp Med Biol 2002;507:269-74 PMID 12664596
  • Cyclic ADP-ribose contributes to contraction and Ca2+ release by M1 muscarinic receptor activation in coronary arterial smooth muscle. (Ge ZD, Zhang DX, Chen YF, Yi FX, Zou AP, Campbell WB, Li PL) J Vasc Res 2003 Jan-Feb;40(1):28-36 PMID 12644723
  • Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels. (Archer SL, Gragasin FS, Wu X, Wang S, McMurtry S, Kim DH, Platonov M, Koshal A, Hashimoto K, Campbell WB, Falck JR, Michelakis ED) Circulation 2003 Feb 11;107(5):769-76 PMID 12578883
  • Liquid chromatographic-mass spectrometric determination of cyclooxygenase metabolites of arachidonic acid in cultured cells. (Nithipatikom K, Laabs ND, Isbell MA, Campbell WB) J Chromatogr B Analyt Technol Biomed Life Sci 2003 Feb 25;785(1):135-45 PMID 12535846
  • Role of contaminating platelets in thromboxane synthesis in primary cultures of human umbilical vein endothelial cells. (Pfister SL, Hughes MJ, Rosolowsky M, Campbell WB) Prostaglandins Other Lipid Mediat 2002 Sep;70(1-2):39-49 PMID 12428677
  • Comparison of vasodilatory properties of 14,15-EET analogs: structural requirements for dilation. (Falck JR, Krishna UM, Reddy YK, Kumar PS, Reddy KM, Hittner SB, Deeter C, Sharma KK, Gauthier KM, Campbell WB) Am J Physiol Heart Circ Physiol 2003 Jan;284(1):H337-49 PMID 12388250
  • Simultaneous in situ monitoring of intracellular Ca2+ and NO in endothelium of coronary arteries. (Yi FX, Zhang AY, Campbell WB, Zou AP, Van Breemen C, Li PL) Am J Physiol Heart Circ Physiol 2002 Dec;283(6):H2725-32 PMID 12388315
  • Effects of epoxyeicosatrienoic acids on polymorphonuclear leukocyte function. (Pratt PF, Rosolowsky M, Campbell WB) Life Sci 2002 Apr 21;70(21):2521-33 PMID 12173415
  • 14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries. (Gauthier KM, Deeter C, Krishna UM, Reddy YK, Bondlela M, Falck JR, Campbell WB) Circ Res 2002 May 17;90(9):1028-36 PMID 12016270
  • 14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels. (Campbell WB, Deeter C, Gauthier KM, Ingraham RH, Falck JR, Li PL) Am J Physiol Heart Circ Physiol 2002 May;282(5):H1656-64 PMID 11959628
  • Role of FKBP12.6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscle. (Tang WX, Chen YF, Zou AP, Campbell WB, Li PL) Am J Physiol Heart Circ Physiol 2002 Apr;282(4):H1304-10 PMID 11893565
  • Role of ADP-ribose in 11,12-EET-induced activation of K(Ca) channels in coronary arterial smooth muscle cells. (Li PL, Zhang DX, Ge ZD, Campbell WB) Am J Physiol Heart Circ Physiol 2002 Apr;282(4):H1229-36 PMID 11893556
  • What is new in endothelium-derived hyperpolarizing factors? (Campbell WB, Gauthier KM) Curr Opin Nephrol Hypertens 2002 Mar;11(2):177-83 PMID 11856910
  • Characteristics and superoxide-induced activation of reconstituted myocardial mitochondrial ATP-sensitive potassium channels. (Zhang DX, Chen YF, Campbell WB, Zou AP, Gross GJ, Li PL) Circ Res 2001 Dec 7;89(12):1177-83 PMID 11739283
  • Liquid chromatographic-electrospray ionization-mass spectrometric analysis of cytochrome P450 metabolites of arachidonic acid. (Nithipatikom K, Grall AJ, Holmes BB, Harder DR, Falck JR, Campbell WB) Anal Biochem 2001 Nov 15;298(2):327-36 PMID 11700990
  • Effect of nitric oxide on calcium-induced calcium release in coronary arterial smooth muscle. (Li N, Zou AP, Ge ZD, Campbell WB, Li PL) Gen Pharmacol 2000 Jul;35(1):37-45 PMID 11679204
  • Cytochromes P450 and flavin monooxygenases--targets and sources of nitric oxide. (Morgan ET, Ullrich V, Daiber A, Schmidt P, Takaya N, Shoun H, McGiff JC, Oyekan A, Hanke CJ, Campbell WB, Park CS, Kang JS, Yi HG, Cha YN, Mansuy D, Boucher JL) Drug Metab Dispos 2001 Nov;29(11):1366-76 PMID 11602511
  • Role of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factor in bovine coronary arteries. (Campbell WB, Falck JR, Gauthier K) Med Sci Monit 2001 Jul-Aug;7(4):578-84 PMID 11433180
  • Production and metabolism of ceramide in normal and ischemic-reperfused myocardium of rats. (Zhang DX, Fryer RM, Hsu AK, Zou AP, Gross GJ, Campbell WB, Li PL) Basic Res Cardiol 2001 May-Jun;96(3):267-74 PMID 11403420
  • Prologue: EDHF--what is it? (Campbell WB, Harder DR) Am J Physiol Heart Circ Physiol 2001 Jun;280(6):H2413-6 PMID 11356592
  • Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs. (Nithipatikom K, DiCamelli RF, Kohler S, Gumina RJ, Falck JR, Campbell WB, Gross GJ) Anal Biochem 2001 May 1;292(1):115-24 PMID 11319825
  • Endothelium-independent, ouabain-sensitive relaxation of bovine coronary arteries by EETs. (Pratt PF, Li P, Hillard CJ, Kurian J, Campbell WB) Am J Physiol Heart Circ Physiol 2001 Mar;280(3):H1113-21 PMID 11179054
  • Antianalgesic action of nociceptin originating in the brain is mediated by spinal prostaglandin E(2) in mice. (Rady JJ, Campbell WB, Fujimoto JM) J Pharmacol Exp Ther 2001 Jan;296(1):7-14 PMID 11123356
  • cADP-ribose activates reconstituted ryanodine receptors from coronary arterial smooth muscle. (Li PL, Tang WX, Valdivia HH, Zou AP, Campbell WB) Am J Physiol Heart Circ Physiol 2001 Jan;280(1):H208-15 PMID 11123235
  • Endothelial cell nitric oxide inhibits aldosterone synthesis in zona glomerulosa cells: modulation by oxygen. (Hanke CJ, Campbell WB) Am J Physiol Endocrinol Metab 2000 Oct;279(4):E846-54 PMID 11001767
  • Nitric oxide inhibits Ca(2+) mobilization through cADP-ribose signaling in coronary arterial smooth muscle cells. (Yu JZ, Zhang DX, Zou AP, Campbell WB, Li PL) Am J Physiol Heart Circ Physiol 2000 Sep;279(3):H873-81 PMID 10993745
  • Determination of EETs using microbore liquid chromatography with fluorescence detection. (Nithipatikom K, Pratt PF, Campbell WB) Am J Physiol Heart Circ Physiol 2000 Aug;279(2):H857-62 PMID 10924087
  • Impaired activation of cytosolic phospolipase A(2) in inflamed canine colonic circular muscle. (Ali I, Campbell WB, Sarna SK) Gastroenterology 2000 Jul;119(1):62-70 PMID 10889155
  • Production of 20-HETE and its role in autoregulation of cerebral blood flow. (Gebremedhin D, Lange AR, Lowry TF, Taheri MR, Birks EK, Hudetz AG, Narayanan J, Falck JR, Okamoto H, Roman RJ, Nithipatikom K, Campbell WB, Harder DR) Circ Res 2000 Jul 7;87(1):60-5 PMID 10884373
  • Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. (Jarrahian A, Manna S, Edgemond WS, Campbell WB, Hillard CJ) J Neurochem 2000 Jun;74(6):2597-606 PMID 10820223
  • New role for epoxyeicosatrienoic acids as anti-inflammatory mediators. (Campbell WB) Trends Pharmacol Sci 2000 Apr;21(4):125-7 PMID 10740283
  • Synthesis and characterization of a fluorescent substrate for the N-arachidonoylethanolamine (anandamide) transmembrane carrier. (Muthian S, Nithipatikom K, Campbell WB, Hillard CJ) J Pharmacol Exp Ther 2000 Apr;293(1):289-95 PMID 10734181
  • Inhibition of cADP-ribose formation produces vasodilation in bovine coronary arteries. (Geiger J, Zou AP, Campbell WB, Li PL) Hypertension 2000 Jan;35(1 Pt 2):397-402 PMID 10642331
  • Inhibition of adrenal cell aldosterone synthesis by endogenous nitric oxide release. (Hanke CJ, O'Brien T, Pritchard KA Jr, Campbell WB) Hypertension 2000 Jan;35(1 Pt 2):324-8 PMID 10642319
  • 25-hydroxycholesterol increases eicosanoids and alters morphology in cultured pulmonary artery smooth muscle and endothelial cells. (Wohlfeil ER, Campbell WB) Arterioscler Thromb Vasc Biol 1999 Dec;19(12):2901-8 PMID 10591667
  • Adrenal capillary endothelial cells stimulate aldosterone release through a protein that is distinct from endothelin. (Rosolowsky LJ, Hanke CJ, Campbell WB) Endocrinology 1999 Oct;140(10):4411-8 PMID 10499493
  • 11,12-Epoxyeicosatrienoic acid stimulates endogenous mono-ADP-ribosylation in bovine coronary arterial smooth muscle. (Li PL, Chen CL, Bortell R, Campbell WB) Circ Res 1999 Aug 20;85(4):349-56 PMID 10455063
  • Effect of ceramide on KCa channel activity and vascular tone in coronary arteries. (Li PL, Zhang DX, Zou AP, Campbell WB) Hypertension 1999 Jun;33(6):1441-6 PMID 10373230
  • Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. (Gebremedhin D, Lange AR, Campbell WB, Hillard CJ, Harder DR) Am J Physiol 1999 Jun;276(6 Pt 2):H2085-93 PMID 10362691
  • Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). (Hillard CJ, Manna S, Greenberg MJ, DiCamelli R, Ross RA, Stevenson LA, Murphy V, Pertwee RG, Campbell WB) J Pharmacol Exp Ther 1999 Jun;289(3):1427-33 PMID 10336536
  • Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonic acid in the regulation of tone. (Campbell WB, Harder DR) Circ Res 1999 Mar 5;84(4):484-8 PMID 10066684
  • Airway synthesis of 20-hydroxyeicosatetraenoic acid: metabolism by cyclooxygenase to a bronchodilator. (Jacobs ER, Effros RM, Falck JR, Reddy KM, Campbell WB, Zhu D) Am J Physiol 1999 Feb;276(2 Pt 1):L280-8 PMID 9950890
  • Proceedings of the council for high blood pressure research, 1998 (Campbell WB) Hypertension 1999 Jan;33(1 Pt 2):169 PMID 9931099
  • Identification of the 11,14,15- and 11,12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta. (Pfister SL, Spitzbarth N, Nithipatikom K, Edgemond WS, Falck JR, Campbell WB) J Biol Chem 1998 Nov 20;273(47):30879-87 PMID 9812980
  • Selective effects of the endogenous cannabinoid arachidonylethanolamide (anandamide) on regional cerebral blood flow in the rat. (Stein EA, Fuller SA, Edgemond WS, Campbell WB) Neuropsychopharmacology 1998 Dec;19(6):481-91 PMID 9803424
  • Nitric oxide inhibits aldosterone synthesis by a guanylyl cyclase-independent effect. (Hanke CJ, Drewett JG, Myers CR, Campbell WB) Endocrinology 1998 Oct;139(10):4053-60 PMID 9751482
  • Regulation of KCa-channel activity by cyclic ADP-ribose and ADP-ribose in coronary arterial smooth muscle. (Li PL, Zou AP, Campbell WB) Am J Physiol 1998 Sep;275(3 Pt 2):H1002-10 PMID 9724306
  • Bioassay of an endothelium-derived hyperpolarizing factor from bovine coronary arteries: role of a cytochrome P450 metabolite. (Gebremedhin D, Harder DR, Pratt PF, Campbell WB) J Vasc Res 1998 Jul-Aug;35(4):274-84 PMID 9701712
  • Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation. (Edgemond WS, Hillard CJ, Falck JR, Kearn CS, Campbell WB) Mol Pharmacol 1998 Jul;54(1):180-8 PMID 9658204
  • Synthesis and characterization of diazomethylarachidonyl ketone: an irreversible inhibitor of N-arachidonylethanolamine amidohydrolase. (Edgemond WS, Greenberg MJ, McGinley PJ, Muthian S, Campbell WB, Hillard CJ) J Pharmacol Exp Ther 1998 Jul;286(1):184-90 PMID 9655859
  • Detection of membrane-bound enzymes in cells using immunoassay and Raman microspectroscopy. (Hawi SR, Rochanakij S, Adar F, Campbell WB, Nithipatikom K) Anal Biochem 1998 Jun 1;259(2):212-7 PMID 9618199
  • Prostaglandin E2-induced aldosterone release is mediated by an EP2 receptor. (Csukas S, Hanke CJ, Rewolinski D, Campbell WB) Hypertension 1998 Feb;31(2):575-81 PMID 9461224
  • N-arachidonylethanolamide relaxation of bovine coronary artery is not mediated by CB1 cannabinoid receptor. (Pratt PF, Hillard CJ, Edgemond WS, Campbell WB) Am J Physiol 1998 Jan;274(1 Pt 2):H375-81 PMID 9458889
  • Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid. (Hillard CJ, Campbell WB) J Lipid Res 1997 Dec;38(12):2383-98 PMID 9458263
  • Methacholine-induced contraction of rabbit pulmonary artery: role of platelet-endothelial transcellular thromboxane synthesis. (Pfister SL, Deinhart DD, Campbell WB) Hypertension 1998 Jan;31(1 Pt 2):206-12 PMID 9453304
  • Effect of selective inhibition of soluble guanylyl cyclase on the K(Ca) channel activity in coronary artery smooth muscle. (Li PL, Jin MW, Campbell WB) Hypertension 1998 Jan;31(1 Pt 2):303-8 PMID 9453320
  • 20-HETE relaxes bovine coronary arteries through the release of prostacyclin. (Pratt PF, Falck JR, Reddy KM, Kurian JB, Campbell WB) Hypertension 1998 Jan;31(1 Pt 2):237-41 PMID 9453309
  • Raman microspectroscopy of intracellular cholesterol crystals in cultured bovine coronary artery endothelial cells. (Hawi SR, Nithipatikom K, Wohlfeil ER, Adar F, Campbell WB) J Lipid Res 1997 Aug;38(8):1591-7 PMID 9300781
  • Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion. (Hillard CJ, Edgemond WS, Jarrahian A, Campbell WB) J Neurochem 1997 Aug;69(2):631-8 PMID 9231721
  • Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein. (Li PL, Campbell WB) Circ Res 1997 Jun;80(6):877-84 PMID 9168791
  • Determination of 14,15-epoxyeicosatrienoic acid and 14,15-dihydroxyeicosatrienoic acid by fluoroimmunoassay. (Nithipatikom K, Falck JR, Bhatt RK, Hanke CJ, Campbell WB) Anal Biochem 1997 Mar 15;246(2):253-9 PMID 9073364
  • 25-Hydroxycholesterol enhances eicosanoid production in cultured bovine coronary artery endothelial cells by increasing prostaglandin G/H synthase-2. (Wohlfeil ER, Campbell WB) Biochim Biophys Acta 1997 Mar 10;1345(1):109-20 PMID 9084508
  • Vascular smooth muscle thromboxane A2 receptors mediate arachidonic acid-induced sudden death in rabbits. (Pfister SL, Kotulock DA, Campbell WB) Hypertension 1997 Jan;29(1 Pt 2):303-9 PMID 9039119
  • Regulation of potassium channels in coronary arterial smooth muscle by endothelium-derived vasodilators. (Li PL, Zou AP, Campbell WB) Hypertension 1997 Jan;29(1 Pt 2):262-7 PMID 9039112
  • Metabolism and actions of ADP-riboses in coronary arterial smooth muscle. (Li P, Zou AP, Campbell WB) Adv Exp Med Biol 1997;419:437-41 PMID 9193686
  • Characterization of normal and malignant human hepatocytes by Raman microspectroscopy. (Hawi SR, Campbell WB, Kajdacsy-Balla A, Murphy R, Adar F, Nithipatikom K) Cancer Lett 1996 Dec 20;110(1-2):35-40 PMID 9018078
  • Contribution of arachidonic acid metabolites to reduced norepinephrine-induced contractions in hypercholesterolemic rabbit aortas. (Pfister SL, Campbell WB) J Cardiovasc Pharmacol 1996 Dec;28(6):784-91 PMID 8961076
  • Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat. (Stein EA, Fuller SA, Edgemond WS, Campbell WB) Br J Pharmacol 1996 Sep;119(1):107-14 PMID 8872363
  • What's new in ... clinical pharmacology and therapeutics. (Kochar MS, Campbell WB) Wis Med J 1996 Sep;95(9):645-6 PMID 8855713
  • Mediators of arachidonic acid-induced relaxation of bovine coronary artery. (Pratt PF, Rosolowsky M, Campbell WB) Hypertension 1996 Jul;28(1):76-82 PMID 8675267
  • Metabolism of arachidonic acid by canine polymorphonuclear leukocytes synthesis of lipoxygenase and omega-oxidized metabolites. (Rosolowsky M, Falck JR, Campbell WB) Biochim Biophys Acta 1996 Apr 19;1300(2):143-50 PMID 8652640
  • Reduced pulmonary artery vasoconstriction in methacholine in cholesterol-fed rabbits. (Pfister SL, Campbell WB) Hypertension 1996 Mar;27(3 Pt 2):804-10 PMID 8613244
  • Vasorelaxation by an endothelium-derived metabolite of arachidonic acid. (Pfister SL, Spitzbarth N, Edgemond W, Campbell WB) Am J Physiol 1996 Mar;270(3 Pt 2):H1021-30 PMID 8780199
  • Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. (Campbell WB, Gebremedhin D, Pratt PF, Harder DR) Circ Res 1996 Mar;78(3):415-23 PMID 8593700
  • Nitro-L-arginine inteferes with the cadmium reduction of nitrate/griess reaction method of measuring nitric oxide production. (Nithipatikom K, Pratt PF, Campbell WB) Eur J Clin Chem Clin Biochem 1996 Feb;34(2):133-7 PMID 8833645
  • Synthesis of hydroxyeicosatetraenoic (HETEs) and epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells. (Rosolowsky M, Campbell WB) Biochim Biophys Acta 1996 Jan 19;1299(2):267-77 PMID 8555273
  • Role of endothelium-derived metabolites of arachidonic acid in enhanced pulmonary artery contractions in female rabbits. (Pfister SL, Campbell WB) Hypertension 1996 Jan;27(1):43-8 PMID 8591886
  • Regulation of calcium influx and catecholamine secretion in chromaffin cells by a cytochrome P450 metabolite of arachidonic acid. (Hildebrandt E, Albanesi JP, Falck JR, Campbell WB) J Lipid Res 1995 Dec;36(12):2599-608 PMID 8847486
  • Simultaneous determination of nitrate and nitrite in biological samples by multichannel flow injection analysis. (Pratt PF, Nithipatikom K, Campbell WB) Anal Biochem 1995 Nov 1;231(2):383-6 PMID 8594989
  • Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. (Hillard CJ, Wilkison DM, Edgemond WS, Campbell WB) Biochim Biophys Acta 1995 Aug 3;1257(3):249-56 PMID 7647100
  • Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone. (Harder DR, Campbell WB, Roman RJ) J Vasc Res 1995 Mar-Apr;32(2):79-92 PMID 7537544
  • The binding of novel phenolic derivatives of anandamide to brain cannabinoid receptors. (Edgemond WS, Campbell WB, Hillard CJ) Prostaglandins Leukot Essent Fatty Acids 1995 Feb-Mar;52(2-3):83-6 PMID 7784462
  • Characterization of ligand binding to the cannabinoid receptor of rat brain membranes using a novel method: application to anandamide. (Hillard CJ, Edgemond WS, Campbell WB) J Neurochem 1995 Feb;64(2):677-83 PMID 7830060
  • Prostaglandin E2 enhances bradykinin-stimulated release of neuropeptides from rat sensory neurons in culture. (Vasko MR, Campbell WB, Waite KJ) J Neurosci 1994 Aug;14(8):4987-97 PMID 7519258
  • Modulation of platelet function by reactive oxygen metabolites. (Ambrosio G, Golino P, Pascucci I, Rosolowsky M, Campbell WB, DeClerck F, Tritto I, Chiariello M) Am J Physiol 1994 Jul;267(1 Pt 2):H308-18 PMID 8048596
  • Hypoxia stimulates prostacyclin synthesis in newborn pulmonary artery endothelium by increasing cyclooxygenase-1 protein. (North AJ, Brannon TS, Wells LB, Campbell WB, Shaul PW) Circ Res 1994 Jul;75(1):33-40 PMID 8013080
  • Decrease in vascular TxA2 receptors in a subgroup of rabbits unresponsive to a TxA2 mimetic. (Buzzard CJ, Pfister SL, Halushka PV, Campbell WB) Am J Physiol 1994 Jun;266(6 Pt 2):H2320-6 PMID 8023992
  • Formation and action of a P-450 4A metabolite of arachidonic acid in cat cerebral microvessels. (Harder DR, Gebremedhin D, Narayanan J, Jefcoat C, Falck JR, Campbell WB, Roman R) Am J Physiol 1994 May;266(5 Pt 2):H2098-107 PMID 8203608
  • Endothelial cells stimulate aldosterone release from bovine adrenal zona glomerulosa cells. (Rosolowsky LJ, Campbell WB) Am J Physiol 1994 Jan;266(1 Pt 1):E107-17 PMID 8304436
  • Endothelium-dependent contractions in rabbit pulmonary artery are mediated by thromboxane A2. (Buzzard CJ, Pfister SL, Campbell WB) Circ Res 1993 May;72(5):1023-34 PMID 8477518
  • Role of PGI2 and epoxyeicosatrienoic acids in relaxation of bovine coronary arteries to arachidonic acid. (Rosolowsky M, Campbell WB) Am J Physiol 1993 Feb;264(2 Pt 2):H327-35 PMID 8447448
  • Oxygen modulates prostacyclin synthesis in ovine fetal pulmonary arteries by an effect on cyclooxygenase. (Shaul PW, Campbell WB, Farrar MA, Magness RR) J Clin Invest 1992 Dec;90(6):2147-55 PMID 1334969
  • Arachidonic acid- and acetylcholine-induced relaxations of rabbit aorta. (Pfister SL, Campbell WB) Hypertension 1992 Nov;20(5):682-9 PMID 1330923
  • Inhibition of renin secretion from rat renal cortical slices by (R)-12-HETE. (Henrich WL, Falck JR, Campbell WB) Am J Physiol 1992 Oct;263(4 Pt 2):F665-70 PMID 1415738
  • Bradykinin stimulates aldosterone release from cultured bovine adrenocortical cells through bradykinin B2 receptors. (Rosolowsky LJ, Campbell WB) Endocrinology 1992 Apr;130(4):2067-75 PMID 1312440
  • Inhibition of prostaglandin synthesis in human endothelial cells treated with metabolic inhibitors. (Revtyak GE, Campbell WB) Biochim Biophys Acta 1992 Jan 24;1123(2):216-26 PMID 1739750
  • ADP plays an important role in mediating platelet aggregation and cyclic flow variations in vivo in stenosed and endothelium-injured canine coronary arteries. (Yao SK, Ober JC, McNatt J, Benedict CR, Rosolowsky M, Anderson HV, Cui K, Maffrand JP, Campbell WB, Buja LM) Circ Res 1992 Jan;70(1):39-48 PMID 1727687
  • Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta. (Pfister SL, Falck JR, Campbell WB) Am J Physiol 1991 Sep;261(3 Pt 2):H843-52 PMID 1887929
  • Effect of aspirin on local prostaglandin production and serotonin accumulation in a canine model with coronary cyclic flow variations or thrombosis. (Yao SK, Benedict CR, Rosolowsky M, McNatt J, Falinska B, Campbell WB, Buja LM, Willerson JT) J Mol Cell Cardiol 1991 Apr;23(4):473-82 PMID 1942081
  • Metabolism of arachidonic acid by rat adrenal glomerulosa cells: synthesis of hydroxyeicosatetraenoic acids and epoxyeicosatrienoic acids. (Campbell WB, Brady MT, Rosolowsky LJ, Falck JR) Endocrinology 1991 Apr;128(4):2183-94 PMID 1900788
  • Effects of endothelin on in vitro renin secretion. (Moe O, Tejedor A, Campbell WB, Alpern RJ, Henrich WL) Am J Physiol 1991 Apr;260(4 Pt 1):E521-5 PMID 2018117
  • Method of removal of aortic endothelium affects arachidonic acid metabolism and vascular reactivity. (Rosolowsky M, Pfister SL, Buja LM, Clubb FJ Jr, Campbell WB) Eur J Pharmacol 1991 Feb 14;193(3):293-300 PMID 1905235
  • Synthesis and biological activity of epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells. (Rosolowsky M, Falck JR, Campbell WB) Adv Prostaglandin Thromboxane Leukot Res 1991;21A:213-6 PMID 1825542
  • A rapid screening test for HIV-1 antibodies: application to biological studies on human tissue. (Campbell WB, Hughes MJ, Osther K) Life Sci 1991;48(4):347-53 PMID 1990231
  • Endothelial factors in the regulation of renin release. (Campbell WB, Henrich WL) Kidney Int 1990 Oct;38(4):612-7 PMID 2122054
  • Reduced arachidonate metabolism in ATP-depleted myocardial cells occurs early in cell injury. (Revtyak GE, Buja LM, Chien KR, Campbell WB) Am J Physiol 1990 Aug;259(2 Pt 2):H582-91 PMID 2117403
  • The effect of euthanasia technique on vascular arachidonic acid metabolism and vascular and intestinal smooth muscle contractility. (Butler MM, Griffey SM, Clubb FJ Jr, Gerrity LW, Campbell WB) Lab Anim Sci 1990 May;40(3):277-83 PMID 2162983
  • Deacylated lipopolysaccharide inhibits plasminogen activator inhibitor-1, prostacyclin, and prostaglandin E2 induction by lipopolysaccharide but not by tumor necrosis factor-alpha. (Riedo FX, Munford RS, Campbell WB, Reisch JS, Chien KR, Gerard RD) J Immunol 1990 May 1;144(9):3506-12 PMID 2109778
  • Endothelin enhances adrenocorticotropin-stimulated aldosterone release from cultured bovine adrenal cells. (Rosolowsky LJ, Campbell WB) Endocrinology 1990 Apr;126(4):1860-6 PMID 2156668
  • Synthesis of lipoxygenase and epoxygenase products of arachidonic acid by normal and stenosed canine coronary arteries. (Rosolowsky M, Falck JR, Willerson JT, Campbell WB) Circ Res 1990 Mar;66(3):608-21 PMID 2106399
  • Inhibition of renin release by 14,15-epoxyeicosatrienoic acid in renal cortical slices. (Henrich WL, Falck JR, Campbell WB) Am J Physiol 1990 Feb;258(2 Pt 1):E269-74 PMID 2154933
  • Incorporation of hydroxyeicosatetraenoic acids into cellular lipids of adrenal glomerulosa cells: inhibition of aldosterone release by 5-HETE. (Richards CF, Campbell WB) Prostaglandins 1989 Nov;38(5):565-80 PMID 2513620
  • Products of heme-catalyzed transformation of the arachidonate derivative 12-HPETE open S-type K+ channels in Aplysia. (Belardetti F, Campbell WB, Falck JR, Demontis G, Rosolowsky M) Neuron 1989 Oct;3(4):497-505 PMID 2642008
  • Effect of dietary omega-3 fatty acid on serum lipids, platelet function, and atherosclerosis in Watanabe heritable hyperlipidemic rabbits. (Clubb FJ Jr, Schmitz JM, Butler MM, Buja LM, Willerson JT, Campbell WB) Arteriosclerosis 1989 Jul-Aug;9(4):529-37 PMID 2751481
  • Regulation of synthesis of prostacyclin and HETEs in human endothelial cells. (Ibe BO, Falck JR, Johnson AR, Campbell WB) Am J Physiol 1989 Jun;256(6 Pt 1):C1168-75 PMID 2500022
  • Augmented vasoconstrictor responses to serotonin precede development of atherosclerosis in aorta of WHHL rabbit. (Wines PA, Schmitz JM, Pfister SL, Clubb FJ Jr, Buja LM, Willerson JT, Campbell WB) Arteriosclerosis 1989 Mar-Apr;9(2):195-202 PMID 2647071
  • Eicosapentaenoic acid alters vascular reactivity and platelet adhesion in Watanabe heritable hyperlipidemic rabbits. (Pfister SL, Rosolowsky M, Schmitz JM, Clubb FJ Jr, Campbell WB) Eur J Pharmacol 1989 Feb 14;161(1):85-9 PMID 2542038
  • Local platelet activation causes vasoconstriction of large epicardial canine coronary arteries in vivo. Thromboxane A2 and serotonin are possible mediators. (Golino P, Ashton JH, Buja LM, Rosolowsky M, Taylor AL, McNatt J, Campbell WB, Willerson JT) Circulation 1989 Jan;79(1):154-66 PMID 2910540
  • Pulmonary hypertension and pulmonary vascular reactivity in beagles at high altitude. (Grover RF, Johnson RL Jr, McCullough RG, McCullough RE, Hofmeister SE, Campbell WB, Reynolds RC) J Appl Physiol (1985) 1988 Dec;65(6):2632-40 PMID 2975278
  • Characterization of arachidonic acid metabolism in Watanabe heritable hyperlipidemic (WHHL) and New Zealand white (NZW) rabbit aortas. (Pfister SL, Schmitz JM, Willerson JT, Campbell WB) Prostaglandins 1988 Oct;36(4):515-32 PMID 3238004
  • Reduction in the rate of early restenosis after coronary angioplasty by a diet supplemented with n-3 fatty acids. (Dehmer GJ, Popma JJ, van den Berg EK, Eichhorn EJ, Prewitt JB, Campbell WB, Jennings L, Willerson JT, Schmitz JM) N Engl J Med 1988 Sep 22;319(12):733-40 PMID 2842680
  • Guanosine 3',5'-cyclic monophosphate as a mediator of inhibition of renin release. (Henrich WL, McAllister EA, Smith PB, Campbell WB) Am J Physiol 1988 Sep;255(3 Pt 2):F474-8 PMID 2901230
  • Histamine stimulation of prostaglandin and HETE synthesis in human endothelial cells. (Revtyak GE, Hughes MJ, Johnson AR, Campbell WB) Am J Physiol 1988 Aug;255(2 Pt 1):C214-25 PMID 3407766
  • Synthesis and metabolism of leukotrienes by human endothelial cells: influence on prostacyclin release. (Ibe BO, Campbell WB) Biochim Biophys Acta 1988 Jun 15;960(3):309-21 PMID 2838089
  • Cultured bovine coronary arterial endothelial cells synthesize HETEs and prostacyclin. (Revtyak GE, Johnson AR, Campbell WB) Am J Physiol 1988 Jan;254(1 Pt 1):C8-19 PMID 3122593
  • Prostaglandin synthesis in bovine coronary endothelial cells: comparison with other commonly studied endothelial cells. (Revtyak GE, Johnson AR, Campbell WB) Thromb Res 1987 Dec 15;48(6):671-83 PMID 3124291
  • Cooperative mediation by serotonin S2 and thromboxane A2/prostaglandin H2 receptor activation of cyclic flow variations in dogs with severe coronary artery stenoses. (Ashton JH, Ogletree ML, Michel IM, Golino P, McNatt JM, Taylor AL, Raheja S, Schmitz J, Buja LM, Campbell WB) Circulation 1987 Oct;76(4):952-9 PMID 3652429
  • Direct inhibitory effect of atriopeptin III on renin release in primate kidney. (Henrich WL, McAlister EA, Smith PB, Lipton J, Campbell WB) Life Sci 1987 Jul 20;41(3):259-64 PMID 2955183
  • Measurement of prostaglandins by radioimmunoassay. (Campbell WB, Ojeda SR) Methods Enzymol 1987;141:323-41 PMID 3600362
  • Inhibition of cyclic flow variations in stenosed canine coronary arteries by thromboxane A2/prostaglandin H2 receptor antagonists. (Ashton JH, Schmitz JM, Campbell WB, Ogletree ML, Raheja S, Taylor AL, Fitzgerald C, Buja LM, Willerson JT) Circ Res 1986 Nov;59(5):568-78 PMID 3542279
  • Effect of atriopeptin III on renin release in vitro. (Henrich WL, Needleman P, Campbell WB) Life Sci 1986 Sep 15;39(11):993-1001 PMID 3018407
  • Inhibition of prostaglandin synthesis by glucocorticoids in human endothelial cells. (Lewis GD, Campbell WB, Johnson AR) Endocrinology 1986 Jul;119(1):62-9 PMID 3087737
  • Importance of calcium in renal renin release. (Henrich WL, Campbell WB) Am J Physiol 1986 Jul;251(1 Pt 1):E98-103 PMID 3014894
  • Effects of angiotensin, prostaglandin E2 and indomethacin on the early and late steps of aldosterone biosynthesis in isolated adrenal cells. (Campbell WB, Brady MT, Gomez-Sanchez CE) J Steroid Biochem 1986 Apr;24(4):865-70 PMID 3458007
  • Serotonin as a mediator of cyclic flow variations in stenosed canine coronary arteries. (Ashton JH, Benedict CR, Fitzgerald C, Raheja S, Taylor A, Campbell WB, Buja LM, Willerson JT) Circulation 1986 Mar;73(3):572-8 PMID 2936531
  • Specific incorporation of 5-hydroxy-6,8,11,14-eicosatetraenoic acid into phosphatidylcholine in human endothelial cells. (Richards CF, Johnson AR, Campbell WB) Biochim Biophys Acta 1986 Feb 28;875(3):569-81 PMID 3004591
  • Renal hemodynamic effects of therapeutic plasma levels of sulindac sulfide during hemorrhage. (Henrich WL, Brater DC, Campbell WB) Kidney Int 1986 Feb;29(2):484-9 PMID 3754595
  • Synthesis of dihomoprostaglandins from adrenic acid (7,10,13,16-docosatetraenoic acid) by human endothelial cells. (Campbell WB, Falck JR, Okita JR, Johnson AR, Callahan KS) Biochim Biophys Acta 1985 Oct 23;837(1):67-76 PMID 3931686
  • Vascular prostaglandin and thromboxane production in a canine model of myocardial ischemia. (Schmitz JM, Apprill PG, Buja LM, Willerson JT, Campbell WB) Circ Res 1985 Aug;57(2):223-31 PMID 3926340
  • Cyclic blood flow variations induced by platelet-activating factor in stenosed canine coronary arteries despite inhibition of thromboxane synthetase, serotonin receptors, and alpha-adrenergic receptors. (Apprill P, Schmitz JM, Campbell WB, Tilton G, Ashton J, Raheja S, Buja LM, Willerson JT) Circulation 1985 Aug;72(2):397-405 PMID 2988822
  • Absence of prostacyclin involvement in angiotensin-induced aldosterone secretion in rat adrenal cells. (Campbell WB, Gomez-Sanchez CE) Endocrinology 1985 Jul;117(1):279-86 PMID 3924581
  • Inhibition of aldosterone biosynthesis by atriopeptins in rat adrenal cells. (Campbell WB, Currie MG, Needleman P) Circ Res 1985 Jul;57(1):113-8 PMID 2988817
  • Enhancement of the antiaggregatory activity of prostacyclin by propranolol in human platelets. (Callahan KS, Johnson AR, Campbell WB) Circulation 1985 Jun;71(6):1237-46 PMID 2986877
  • Arachidonic acid metabolites and endothelial injury: studies with cultures of human endothelial cells. (Johnson AR, Revtyak G, Campbell WB) Fed Proc 1985 Jan;44(1 Pt 1):19-24 PMID 2981729
  • Endothelial cells metabolize but do not synthesize leukotrienes. (Johnson AR, Revtyak GE, Ibe BO, Campbell WB) Prog Clin Biol Res 1985;199:185-96 PMID 2999822
  • Effects of ibuprofen, naproxen, and sulindac on prostaglandins in men. (Brater DC, Anderson S, Baird B, Campbell WB) Kidney Int 1985 Jan;27(1):66-73 PMID 3884880
  • Conversion from chronic to acute coronary artery disease: speculation regarding mechanisms. (Willerson JT, Campbell WB, Winniford MD, Schmitz J, Apprill P, Firth BG, Ashton J, Smitherman T, Bush L, Buja LM) Am J Cardiol 1984 Dec 1;54(10):1349-54 PMID 6391133
  • Does indomethacin attenuate the coronary vasodilatory effect of nitroglycerin? (Winniford MD, Jackson J, Malloy CR, Rehr RB, Campbell WB, Hillis LD) J Am Coll Cardiol 1984 Dec;4(6):1114-7 PMID 6438204
  • The effects of alpha 2-adrenergic and serotonergic receptor antagonists on cyclic blood flow alterations in stenosed canine coronary arteries. (Bush LR, Campbell WB, Kern K, Tilton GD, Apprill P, Ashton J, Schmitz J, Buja LM, Willerson JT) Circ Res 1984 Nov;55(5):642-52 PMID 6488486
  • Acute systemic and coronary hemodynamic and serologic responses to cigarette smoking in long-term smokers with atherosclerotic coronary artery disease. (Nicod P, Rehr R, Winniford MD, Campbell WB, Firth BG, Hillis LD) J Am Coll Cardiol 1984 Nov;4(5):964-71 PMID 6548482
  • Mechanism of nitroglycerin-induced coronary dilatation: lack of relation to intracoronary thromboxane concentrations. (Rehr RB, Jackson JA, Winniford MD, Campbell WB, Hillis LD) Am J Cardiol 1984 Nov 1;54(8):971-4 PMID 6437206
  • Dependence of urinary prostaglandin E2 excretion on urinary volume rather than solute handling or segmental nephron function in man. (Kaojarern S, Chennavasin P, Burdette A, Campbell WB, Brater DC) Clin Sci (Lond) 1984 Oct;67(4):413-20 PMID 6590165
  • Alterations in coronary blood flow induced by cigarette smoking: lack of relation to plasma arginine vasopressin concentrations. (Nicod P, Winniford MD, Campbell WB, Rehr RB, Firth BG, Hillis LD) Am J Cardiol 1984 Sep 1;54(6):667-8 PMID 6475792
  • Relationship between PG and beta-adrenergic pathways to renin release in rat renal cortical slices. (Henrich WL, Campbell WB) Am J Physiol 1984 Sep;247(3 Pt 1):E343-8 PMID 6089584
  • Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries. (Bush LR, Campbell WB, Buja LM, Tilton GD, Willerson JT) Circulation 1984 Jun;69(6):1161-70 PMID 6546902
  • The systemic beta-adrenergic pathway to renin secretion: relationships with the renal prostaglandin system. (Henrich WL, Campbell WB) Endocrinology 1983 Dec;113(6):2247-54 PMID 6139275
  • Hemodynamic effects of intravenous prostacyclin in stable angina pectoris. (Firth BG, Winniford MD, Campbell WB, Hillis LD) Am J Cardiol 1983 Sep 1;52(5):439-43 PMID 6351580
  • Effects of provocation on transcardiac thromboxane in patients with coronary artery disease. (Hirsh PD, Firth BG, Campbell WB, Dehmer GJ, Willerson JT, Hillis LD) Am J Cardiol 1983 Mar 1;51(5):727-33 PMID 6829431
  • Synergistic effect of captopril with hydrochlorothiazide for the treatment of low-renin hypertensive black patients. (Holland OB, von Kuhnert L, Campbell WB, Anderson RJ) Hypertension 1983 Mar-Apr;5(2):235-9 PMID 6337951
  • Effects of the selective thromboxane synthetase inhibitor, dazoxiben, on cyclic flow variations in stenosed canine coronary arteries. (Bush LR, Campbell WB, Tilton GD, Buja LM, Willerson JT) Trans Assoc Am Physicians 1983;96:103-12 PMID 6687298
  • Interactions of the arterial wall, plaque, and platelets in myocardial ischemia and infarction. (Hillis LD, Hirsh PD, Campbell WB, Firth BG) Cardiovasc Clin 1983;14(1):31-44 PMID 6352026
  • Stimulation of prostaglandin formation by vasoactive mediators in cultured human endothelial cells. (Alhenc-Gelas F, Tsai SJ, Callahan KS, Campbell WB, Johnson AR) Prostaglandins 1982 Nov;24(5):723-42 PMID 6819604
  • An increase in hypothalamic capacity to synthesize prostaglandin E2 precedes the first preovulatory surge of gonadotropins. (Ojeda SR, Campbell WB) Endocrinology 1982 Oct;111(4):1031-7 PMID 6811254
  • Urinary excretion of prostaglandin E2, prostaglandin F2 alpha, and thromboxane B2 in normotensive and hypertensive subjects on varying sodium intakes. (Campbell WB, Holland OB, Adams BV, Gomez-Sanchez CE) Hypertension 1982 Sep-Oct;4(5):735-41 PMID 7049923
  • Influence of blood sampling site and technique on thromboxane concentrations in patients with ischemic heart disease. (Hirsh PD, Firth BG, Campbell WB, Willerson JT, Hillis LD) Am Heart J 1982 Aug;104(2 Pt 1):234-7 PMID 7102506
  • Dissociation of systemic and renal effects in endotoxemia. Prostaglandin inhibition uncovers an important role of renal nerves. (Henrich WL, Hamasaki Y, Said SI, Campbell WB, Cronin RE) J Clin Invest 1982 Mar;69(3):691-9 PMID 7037854
  • Effects of short-term beta blockade on blood pressure, plasma thromboxane B2, and plasma and urinary prostaglandins E2 and F2 alpha in normal subjects. (Graham RM, Campbell WB, Jackson EK) Clin Pharmacol Ther 1982 Mar;31(3):324-9 PMID 6120775
  • Anti-platelet activity of beta-adrenergic antagonists: inhibition of thromboxane synthesis and platelet aggregation in patients receiving long-term propranolol treatment. (Campbell WB, Johnson AR, Callahan KS, Graham RM) Lancet 1981 Dec 19-26;2(8260-61):1382-4 PMID 6118758
  • Prostaglandins and ischemic heart disease. (Hirsh PD, Campbell WB, Willerson JT, Hillis LD) Am J Med 1981 Dec;71(6):1009-26 PMID 7032286
  • Speculative approaches in hypertension: concepts and drugs of the future. (Graham RM, Campbell WB) Fed Proc 1981 Jun;40(8):2291-5 PMID 6263717
  • Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease. (Hirsh PD, Hillis LD, Campbell WB, Firth BG, Willerson JT) N Engl J Med 1981 Mar 19;304(12):685-91 PMID 6894016
  • Prostacyclin and prostaglandin biosynthesis in human pulmonary endothelial cells. (Johnson AR, Callahan KS, Tsai SC, Campbell WB) Bull Eur Physiopathol Respir 1981;17(4):531-51 PMID 7034822
  • A possible antihypertensive mechanism of propranolol: antagonism of angiotensin II enhancement of sympathetic nerve transmission through prostaglandins. (Jackson EK, Campbell WB) Hypertension 1981 Jan-Feb;3(1):23-33 PMID 6259059
  • Plasma substance P levels in normotensive and hypertensive subjects. (Campbell WB, Holland OB, Gomez-Sanchez CE, Graham RM, Pettinger WA, White AC) Clin Exp Hypertens 1981;3(2):183-93 PMID 6163596
  • The in situ blood perfused rat mesentery; a model for assessing modulation of adrenergic neurotransmission. (Jackson EK, Campbell WB) Eur J Pharmacol 1980 Aug 29;66(2-3):217-24 PMID 6254783
  • Inhibition of hydralazine-induced renin release by indomethacin in the rat. (Campbell WB, Graham RM, Jackson EK) Arch Int Pharmacodyn Ther 1980 Aug;246(2):315-23 PMID 7002082
  • Effects of indomethacin on furosemide-stimulated urinary PGE2 excretion in man. (Brater DC, Beck JM, Adams BV, Campbell WB) Eur J Pharmacol 1980 Jul 25;65(2-3):213-9 PMID 7398787
  • Role of prostaglandins in angiotensin-induced steriodogenesis absence of an effect by prostaglandin E2. (Campbell WB, Gomez-Sanchez CE, Adams BV) Hypertension 1980 Jul-Aug;2(4):471-6 PMID 7399628
  • The pharmacologic alteration of renin release. (Keeton TK, Campbell WB) Pharmacol Rev 1980 Jun;32(2):81-227 PMID 7012850
  • Insulin-induced renin release: blockade by indomethacin in the rat. (Campbell WB, Zimmer JA) Clin Sci (Lond) 1980 May;58(5):415-8 PMID 6993088
  • Effect of indomethacin on hydralazine-induced renin and catecholamine release in the conscious rabbit. (Campbell WB, Graham RM, Jackson EK, Loisel DP, Pettinger WA) Br J Pharmacol 1980;71(2):529-31 PMID 7008885
  • Inhibition of angiotensin II potentiation of sympathetic nerve activity by beta-adrenergic antagonists. (Jackson EK, Campbell WB) Hypertension 1980 Jan-Feb;2(1):90-6 PMID 6102965
  • Attenuation of angiotensin II- and III-induced aldosterone release by prostaglandin synthesis inhibitors. (Campbell WB, Gomez-Sanchez CE, Adams BV, Schmitz JM, Itskovitz HD) J Clin Invest 1979 Dec;64(6):1552-7 PMID 500824
  • Saralasin-induced renin release: its blockade by prostaglandin synthesis inhibitors in the conscious rat. (Campbell WB, Jackson EK, Graham RM) Hypertension 1979 Nov-Dec;1(6):637-42 PMID 120320
  • Cortical and papillary micropuncture examination of chloride transport in segments of the rat kidney during inhibition of prostaglandin production. Possible role for prostaglandins in the chloruresis of acute volume expansion. (Higashihara E, Stokes JB, Kokko JP, Campbell WB, DuBose TD Jr) J Clin Invest 1979 Nov;64(5):1277-87 PMID 500811
  • Role of renal prostaglandins in sympathetically mediated renin relase in the rat. (Campbell WB, Graham RM, Jackson EK) J Clin Invest 1979 Aug;64(2):448-56 PMID 37256
  • Role of substance P in water homeostasis. (Gullner HG, Campbell WB, Pettinger WA) Life Sci 1979 Jun 18;24(25):2351-9 PMID 225622
  • Renal metabolism of substance P in the dog. (Campbell WB, Ward PE) Life Sci 1979 May 21;24(21):1995-2001 PMID 459697
  • Effect of sodium depletion on the steroidogenic and pressor actions of angiotensin in the rat. (Campbell WB, Schmitz JM, Itskovitz HD) Clin Sci (Lond) 1979 Apr;56(4):325-33 PMID 477217
  • (7-Ile) angiotensin III: a relatively selective antagonist of angiotensin steroidogenesis. (Campbell WB, Schmitz JM) Eur J Pharmacol 1979 Mar 1;54(3):209-16 PMID 218823
  • Modulation of adrenergic transmission by angiotensins in the perfused rat mesentery. (Campbell WB, Jackson EK) Am J Physiol 1979 Feb;236(2):H211-7 PMID 217278
  • Effects of substance P on renin release and renal function in anesthetized dogs. (Gullner HG, Campbell WB, Pettinger WA) Life Sci 1979 Jan 15;24(3):237-45 PMID 423702
  • Effect of alterations in dietary potassium on the pressor and steroidogenic effects of angiotensins II and III. (Campbell WB, Schmitz JM) Endocrinology 1978 Dec;103(6):2098-104 PMID 748034
  • The adrenal and vascular effects of angiotensin II and III in sodium depleted rats. (Campbell WB, Schmitz JM, Itskovitz HD) Life Sci 1977 Mar 1;20(5):803-9 PMID 15714763
  • (Des-Asp1) angiotensin I: a study of its pressor and steroidogenic activities in conscious rats. (Campbell WB, Schmitz JM, Itskovitz HD) Endocrinology 1977 Jan;100(1):46-51 PMID 187407
  • Vasodilators, intrarenal distribution of blood flow, and renal function in isolated perfused canine kidneys. (Itskovitz HD, Campbell WB) Proc Soc Exp Biol Med 1976 Oct;153(1):161-5 PMID 995938
  • Effect of histamine and antihistamines on renal hemodynamics and functions in the isolated perfused canine kidney. (Campbell WB, Itskovitz HD) J Pharmacol Exp Ther 1976 Sep;198(3):661-7 PMID 10420
  • Organ specificity of angiotensin II and Des-aspartyl angiotensin II in the conscious rat. (Campbell WB, Pettinger WA) J Pharmacol Exp Ther 1976 Aug;198(2):450-6 PMID 948036
  • The effects of altered sodium balance and adrenergic blockade on renin release induced in rats by angiotensin antagonism. (Keeton TK, Pettinger WA, Campbell WB) Circ Res 1976 Jun;38(6):531-9 PMID 1269103
  • Evidence for a renal alpha-adrenergic receptor inhibiting renin release. (Pettinger WA, Keeton TK, Campbell WB, Harper DC) Circ Res 1976 May;38(5):338-46 PMID 5201
  • Renin and hemodynamic changes via central adrenergic, cholinergic, and sodium receptor mechanisms in conscious rats. (Morris M, Campbell WB, Pettinger WA) Proc Soc Exp Biol Med 1976 Jan;151(1):101-4 PMID 2926
  • Sodium chloride suppression of renin release in the unanesthetized rat. (Campbell WB, Pettinger WA) Endocrinology 1975 Dec;97(6):1394-7 PMID 1204570
  • Vasodilating antihypertensive drug-induced aldosterone release--a study of endogenous angiotensin-mediated aldosterone release in the rat. (Campbell WB, Pettinger WA, Keeton K, Brooks SN) J Pharmacol Exp Ther 1975 Apr;193(1):166-75 PMID 1167223
  • Renin release, an artifact of anesthesia and its implications in rats. (Pettinger WA, Tanaka K, Keeton K, Campbell WB, Brooks SN) Proc Soc Exp Biol Med 1975 Mar;148(3):625-30 PMID 1129282
  • Letter: Renin in the spontaneously hypertensive rat. (Campbell WB, Sen S) Circ Res 1974 Dec;35(6):961-3 PMID 4430086
  • Angiotensin II- and angiotensin 3-induced aldosterone release vivo in the rat. (Campbell WB, Brooks SN, Pettinger WA) Science 1974 May 31;184(4140):994-6 PMID 4363578
  • Adrenergic component of renin release induced by vasodilating antihypertensive drugs in the rat. (Pettinger WA, Campbell WB, Keeton K) Circ Res 1973 Jul;33(1):82-6 PMID 4765702
  • Grants and Awards

  • Endothelial Lipoxygenase Metabolites and Vascular Tone (#9206893 06/01/2011 - 05/31/2015) Sponsor: NIH Heart Lung and Blood Institute
  • Eicosanoid Synthesis and Function in Coronary Vessels (#9204609 06/01/2007 - 05/31/2012) Sponsor: NIH Heart Lung and Blood Institute
  • Nitric Oxide Regulation of Adrenal Steroidogenesis (#9202179 08/01/2001 - 07/31/2006) Sponsor: NIH Diabetes, Digestive and Kidney Diseases
  • State of Wisconsin Prostate Cancer Tax Check-Off for 2009 Tax Year (#9950016 07/01/2010 - 06/30/2015) Sponsor: State of Wisconsin
  • Regulation of Adrenal Vascular Tone by Steroidogenic Cells (#9204119 06/01/2006 - 12/14/2011) Sponsor: NIH Heart Lung and Blood Institute
  • TY08 State of Wisconsin Breast Cancer Research Tax Check-Off Program (#9950014 08/01/2009 - 06/30/2017) Sponsor: State of Wisconsin
  • Eicosanoids, Vascular Tone and Blood Pressure (#9203516 01/01/2005 - 09/30/2009) Sponsor: NIH Heart Lung and Blood Institute
  • Biochemistry of Anadamide, An Endogenous Cannabinoid (#9204540 04/01/2007 - 09/30/2012) Sponsor: NIH Drug Abuse
  • Regulation of Adrenal Vascular Tone by Steroidogenic Cells (#9207239 12/15/2011 - 11/30/2015) Sponsor: NIH Heart Lung and Blood Institute
  • Eicosanoid Synthesis and Function in Coronary Vessels (#9202447 06/01/2002 - 05/31/2007) Sponsor: NIH Heart Lung and Blood Institute
  • TY08 State of Wisconsin Prostate Cancer Research Tax Check-Off Program (#9950013 08/01/2009 - 06/30/2017) Sponsor: State of Wisconsin
  • State of Wisconsin Breast Cancer Tax Check-Off for 2009 Tax Year (#9950017 07/01/2010 - 06/30/2015) Sponsor: State of Wisconsin
  • Biochemistry of Anadamide, An Endogenous Cannabinoid (#9201820 08/15/2000 - 05/31/2006) Sponsor: NIH Drug Abuse