Medical College of Wisconsin
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Zelmira Lazarova MD

Zelmira Lazarova MD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Dermatology
Program: General

Member of the MCW Cancer Center


Publications

  • Aberrant expression of laminin-332 promotes cell proliferation and cyst growth in ARPKD. (Vijayakumar S, Dang S, Marinkovich MP, Lazarova Z, Yoder B, Torres VE, Wallace DP) Am J Physiol Renal Physiol 2014 Mar 15;306(6):F640-54 PMID 24370592
  • EGFRvIII expression in squamous cell carcinoma of the skin. (Dziunycz PJ, Lazarova Z, Duncan N, Wong S, Neuburg M, Hofbauer GF, Olasz EB) JAMA Dermatol 2013 Oct;149(10):1240-2 PMID 23986462
  • A Synthetic Superoxide Dismutase/Catalase Mimetic EUK-207 Mitigates Radiation Dermatitis and Promotes Wound Healing in Irradiated Rat Skin. (Doctrow SR, Lopez A, Schock AM, Duncan NE, Jourdan MM, Olasz EB, Moulder JE, Fish BL, Mäder M, Lazar J, Lazarova Z) J Invest Dermatol 2013 Jun;133(6):1691 PMID 23407392
  • A synthetic superoxide dismutase/catalase mimetic EUK-207 mitigates radiation dermatitis and promotes wound healing in irradiated rat skin. (Doctrow SR, Lopez A, Schock AM, Duncan NE, Jourdan MM, Olasz EB, Moulder JE, Fish BL, Mäder M, Lazar J, Lazarova Z) J Invest Dermatol 2013 Apr;133(4):1088-96 PMID 23190879
  • Laminin 332 deposition is diminished in irradiated skin in an animal model of combined radiation and wound skin injury. (Jourdan MM, Lopez A, Olasz EB, Duncan NE, Demara M, Kittipongdaja W, Fish BL, Mäder M, Schock A, Morrow NV, Semenenko VA, Baker JE, Moulder JE, Lazarova Z) Radiat Res 2011 Nov;176(5):636-48 PMID 21854211
  • Salen Mn complexes mitigate radiation injury in normal tissues. (Rosenthal RA, Fish B, Hill RP, Huffman KD, Lazarova Z, Mahmood J, Medhora M, Molthen R, Moulder JE, Sonis ST, Tofilon PJ, Doctrow SR) Anticancer Agents Med Chem 2011 May 1;11(4):359-72 PMID 21453241
  • Transient anti-CD40L co-stimulation blockade prevents immune responses against human bullous pemphigoid antigen 2: implications for gene therapy. (Lanschuetzer CM, Olasz EB, Lazarova Z, Yancey KB) J Invest Dermatol 2009 May;129(5):1203-7 PMID 19037236
  • IgG anti-laminin-332 autoantibodies are present in a subset of patients with mucous membrane, but not bullous, pemphigoid. (Lazarova Z, Salato VK, Lanschuetzer CM, Janson M, Fairley JA, Yancey KB) J Am Acad Dermatol 2008 Jun;58(6):951-8 PMID 18396347
  • Orf-induced immunobullous disease: A distinct autoimmune blistering disorder. (White KP, Zedek DC, White WL, Simpson EL, Hester E, Morrison L, Lazarova Z, Liu D, Scagliarini A, Kurtz SE, White CR Jr, Yancey KB, Blauvelt A) J Am Acad Dermatol 2008 Jan;58(1):49-55 PMID 17919774
  • Effect of reflux-induced inflammation on transient receptor potential vanilloid one (TRPV1) expression in primary sensory neurons innervating the oesophagus of rats. (Banerjee B, Medda BK, Lazarova Z, Bansal N, Shaker R, Sengupta JN) Neurogastroenterol Motil 2007 Aug;19(8):681-91 PMID 17640184
  • A widening perspective regarding the relationship between anti-epiligrin cicatricial pemphigoid and cancer. (Sadler E, Lazarova Z, Sarasombath P, Yancey KB) J Dermatol Sci 2007 Jul;47(1):1-7 PMID 17467241
  • Pemphigus vulgaris presenting in a radiation portal. (Robbins AC, Lazarova Z, Janson MM, Fairley JA) J Am Acad Dermatol 2007 May;56(5 Suppl):S82-5 PMID 17434046
  • Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease. (Horowitz S, Binion DG, Nelson VM, Kanaa Y, Javadi P, Lazarova Z, Andrekopoulos C, Kalyanaraman B, Otterson MF, Rafiee P) Am J Physiol Gastrointest Liver Physiol 2007 May;292(5):G1323-36 PMID 17218473
  • Ocular involvement in anti-epiligrin cicatricial pemphigoid. (Nischler C, Sadler E, Lazarova Z, Stoiber J, Ruckhofer J, Pohla-Gubo G, Emberger M, Bauer JW, Grabner G, Hintner H) Eur J Ophthalmol 2006 Nov-Dec;16(6):867-9 PMID 17191196
  • IgG autoantibodies to type VII collagen and an exclusive IgG3 reactivity to the laminin alpha3 chain in a patient with an autoimmune subepidermal blistering disease. (Baican A, Hirako Y, Lazarova Z, Yancey KB, Zillikens D, Sitaru C) J Am Acad Dermatol 2005 Sep;53(3):517-22 PMID 16112366
  • Role of intramolecular epitope spreading in pemphigus vulgaris. (Salato VK, Hacker-Foegen MK, Lazarova Z, Fairley JA, Lin MS) Clin Immunol 2005 Jul;116(1):54-64 PMID 15925832
  • Comparative analysis of methods for detection of anti-laminin 5 autoantibodies in patients with anti-epiligrin cicatricial pemphigoid. (Lazarova Z, Sitaru C, Zillikens D, Yancey KB) J Am Acad Dermatol 2004 Dec;51(6):886-92 PMID 15583578
  • Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance? (Rosenblum MD, Olasz EB, Yancey KB, Woodliff JE, Lazarova Z, Gerber KA, Truitt RL) J Invest Dermatol 2004 Nov;123(5):880-7 PMID 15482475
  • Anti-epiligrin cicatricial pemphigoid: clinical findings, immunopathogenesis, and significant associations. (Egan CA, Lazarova Z, Darling TN, Yee C, Yancey KB) Medicine (Baltimore) 2003 May;82(3):177-86 PMID 12792304
  • Paraneoplastic pemphigus in children and adolescents. (Mimouni D, Anhalt GJ, Lazarova Z, Aho S, Kazerounian S, Kouba DJ, Mascaro JM Jr, Nousari HC) Br J Dermatol 2002 Oct;147(4):725-32 PMID 12366419
  • IgG autoantibodies in patients with anti-epiligrin cicatricial pemphigoid recognize the G domain of the laminin 5 alpha-subunit. (Lazarova Z, Yee C, Lazar J, Yancey KB) Clin Immunol 2001 Oct;101(1):100-5 PMID 11580232
  • Anti-epiligrin cicatricial pemphigoid and relative risk for cancer. (Egan CA, Lazarova Z, Darling TN, Yee C, Coté T, Yancey KB) Lancet 2001 Jun 9;357(9271):1850-1 PMID 11410196
  • The 120-kDa soluble ectodomain of type XVII collagen is recognized by autoantibodies in patients with pemphigoid and linear IgA dermatosis. (Roh JY, Yee C, Lazarova Z, Hall RP, Yancey KB) Br J Dermatol 2000 Jul;143(1):104-11 PMID 10886143
  • Fab fragments directed against laminin 5 induce subepidermal blisters in neonatal mice. (Lazarova Z, Hsu R, Briggaman RA, Yancey KB) Clin Immunol 2000 Apr;95(1 Pt 1):26-32 PMID 10794429
  • Antiepiligrin cicatricial pemphigoid. (Hsu RC, Lazarova Z, Lee HG, Tung YC, Yu HS) J Am Acad Dermatol 2000 May;42(5 Pt 1):841-4 PMID 10775868
  • Human anti-laminin 5 autoantibodies induce subepidermal blisters in an experimental human skin graft model. (Lazarova Z, Hsu R, Yee C, Yancey KB) J Invest Dermatol 2000 Jan;114(1):178-84 PMID 10620135
  • Antiepiligrin cicatricial pemphigoid: an underdiagnosed entity within the spectrum of scarring autoimmune subepidermal bullous diseases? (Leverkus M, Schmidt E, Lazarova Z, Bröcker EB, Yancey KB, Zillikens D) Arch Dermatol 1999 Sep;135(9):1091-8 PMID 10490114
  • Paraneoplastic cicatricial pemphigoid. (Setterfield J, Shirlaw PJ, Lazarova Z, Bryant BM, Bhogal BS, Harman K, Challacombe SJ, Black MM) Br J Dermatol 1999 Jul;141(1):127-31 PMID 10417528
  • Anti-epiligrin cicatricial pemphigoid with IgG autoantibodies to the beta and gamma subunits of laminin 5. (Fujimoto W, Toi Y, Okazaki F, Lazarova Z, Yancey KB, Arata J) J Am Acad Dermatol 1999 Apr;40(4):637-9 PMID 10188690
  • Antiepiligrin cicatricial pemphigoid represents an autoimmune response to subunits present in laminin 5 (alpha3beta3gamma2). (Lazarova Z, Hsu R, Yee C, Yancey KB) Br J Dermatol 1998 Nov;139(5):791-7 PMID 9892943
  • Noncomplement fixing, IgG4 autoantibodies predominate in patients with anti-epiligrin cicatricial pemphigoid. (Hsu R, Lazarova Z, Yee C, Yancey KB) J Invest Dermatol 1997 Oct;109(4):557-61 PMID 9326390
  • The extracellular domain of BPAG2 localizes to anchoring filaments and its carboxyl terminus extends to the lamina densa of normal human epidermal basement membrane. (Masunaga T, Shimizu H, Yee C, Borradori L, Lazarova Z, Nishikawa T, Yancey KB) J Invest Dermatol 1997 Aug;109(2):200-6 PMID 9242508
  • Passive transfer of anti-laminin 5 antibodies induces subepidermal blisters in neonatal mice. (Lazarova Z, Yee C, Darling T, Briggaman RA, Yancey KB) J Clin Invest 1996 Oct 1;98(7):1509-18 PMID 8833897
  • Reactivity of autoantibodies from patients with defined subepidermal bullous diseases against 1 mol/L salt-split skin. Specificity, sensitivity, and practical considerations. (Lazarova Z, Yancey KB) J Am Acad Dermatol 1996 Sep;35(3 Pt 1):398-403 PMID 8784276
  • Studies of patients with anti-epiligrin cicatricial pemphigoid. (Yancey KB, Kirtschig G, Yee C, Lazarova Z) J Dermatol 1995 Nov;22(11):829-35 PMID 8557854
  • Diminished expression of the extracellular domain of bullous pemphigoid antigen 2 (BPAG2) in the epidermal basement membrane of patients with generalized atrophic benign epidermolysis bullosa. (Pohla-Gubo G, Lazarova Z, Giudice GJ, Liebert M, Grassegger A, Hintner H, Yancey KB) Exp Dermatol 1995 Aug;4(4 Pt 1):199-206 PMID 8535614
  • Epiligrin is decreased in papulonodular basal cell carcinoma tumor nest basement membranes and the extracellular matrix of transformed human epithelial cells. (Lazarova Z, Domloge-Hultsch N, Yancey KB) Exp Dermatol 1995 Jun;4(3):121-9 PMID 7551559
  • Autoantibodies from patients with cicatricial pemphigoid target different sites in epidermal basement membrane. (Shimizu H, Masunaga T, Ishiko A, Matsumura K, Hashimoto T, Nishikawa T, Domloge-Hultsch N, Lazarova Z, Yancey KB) J Invest Dermatol 1995 Mar;104(3):370-3 PMID 7861004
  • [Treatment of chlamydia infections and a brief review of the problems]. (Péc J, Kazár J, Auxtová S, Lazárová Z, Péc M, Hajtman A) Bratisl Lek Listy 1995 Mar;96(3):165-7 PMID 7633932
  • Antiepiligrin cicatricial pemphigoid. A subepithelial bullous disorder. (Domloge-Hultsch N, Anhalt GJ, Gammon WR, Lazarova Z, Briggaman R, Welch M, Jabs DA, Huff C, Yancey KB) Arch Dermatol 1994 Dec;130(12):1521-9 PMID 7986125
  • [Quantification of Neisseria gonorrhoeae from the cervicovaginal area in nonpregnant women infected with gonorrhoea]. (Péc J, Moravcík P, Lazarová Z) Bratisl Lek Listy 1994 Mar;95(3):122-4 PMID 7922638
  • Generalized melanosis with malignant melanoma metastasizing to skin--a pathological study with S-100 protein and HMB-45. (Péc J, Plank L, Mináriková E, Palencárová E, Rollová Y, Lazárová Z, Auxtová S, Lauko L) Clin Exp Dermatol 1993 Sep;18(5):454-7 PMID 8252770
  • Mechanical urethritis and ascendent genitourinary infections due to sexual stimulation of the urethra by inserted foreign bodies. (Péc J, Straka S, Novomeský F, Kliment J, Péc M, Lazárová Z) Genitourin Med 1992 Dec;68(6):399-400 PMID 1487263
  • Azithromycin (Sumamed-Pliva) in the treatment of chlamydial genital tract infections in infertile marriages. (Lazarova Z, Kazar J, Auxtova S, Rollova I, Krupova M, Pec M, Pec J) Int J STD AIDS 1992 Nov-Dec;3(6):448-9 PMID 1337473
  • Salicylate intoxication after use of topical salicylic acid ointment by a patient with psoriasis. (Péc J, Strmenová M, Palencárová E, Pullmann R, Funiaková S, Visnovský P, Buchanec J, Lazarová Z) Cutis 1992 Oct;50(4):307-9 PMID 1424799
  • A study of possible causal relations between squamous cell carcinoma of the penis and carcinoma of the cervix uteri. (Péc J Jr, Pécová K, Péc J Sr, Plank L, Homola A, Lazárová Z) Int Urol Nephrol 1992;24(3):313-7 PMID 1328105
  • Squamous cell carcinoma of the penis. Analysis of 24 cases. (Péc J Jr, Péc J Sr, Plank L, Plank J, Lazárová Z, Kliment J) Int Urol Nephrol 1992;24(2):193-200 PMID 1624264
  • Morphological changes of Neisseria gonorrhoeae in amniotic fluid of pregnant women in their midtrimester. (Péc J, Mlyncek M, Moravcík P, Belej K, Lazárová Z) Acta Microbiol Hung 1992;39(1):21-30 PMID 1632195
  • Female paraurethral ducts and glands as the sites of agents of sexually transmitted diseases. (Péc J, Lazárová Z, Kliment J, Pécová K, Palencárová E) Genitourin Med 1991 Oct;67(5):430-1 PMID 1743723
  • Grants and Awards

  • Role of miRNAs in Curtaneous Squamous Cell Carcinmoa Progression and Metastasis (#9208275 09/01/2013 - 08/31/2015) Sponsor: Froedtert Hospital Foundation