Leukocyte hexokinase activity in aging and Alzheimer disease. Dementia 1995;6(4):200-4
Date
07/01/1995Pubmed ID
7550599DOI
10.1159/000106947Scopus ID
2-s2.0-0029018903 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
We determined the effects of clinical variables on hexokinase (HK) activity in leukocytes from Alzheimer's disease (AD) patients and controls. Age accounted for 51% of the variance in HK activity in the young and 23% in the old. Duration of illness in both familial and sporadic AD accounted for HK levels by 32 and 38%, respectively. Hexokinase activity increases with age and does not discriminate between familial and sporadic AD.
Author List
Antuono PG, Ravanelli-Meyer J, Nicholson K, Bloom ASAuthor
Piero G. Antuono MD Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAge Factors
Aged
Aging
Alzheimer Disease
Energy Metabolism
Family
Hexokinase
Humans
Leukocytes
Middle Aged