Adenosine triphosphate pyrophosphohydrolase and neutral inorganic pyrophosphatase in pathologic joint fluids. Elevated pyrophosphohydrolase in calcium pyrophosphate dihydrate crystal deposition disease. Arthritis Rheum 1985 Nov;28(11):1283-8
Date
11/01/1985Pubmed ID
2998408DOI
10.1002/art.1780281113Scopus ID
2-s2.0-0022344564 (requires institutional sign-in at Scopus site) 37 CitationsAbstract
Adenosine triphosphate pyrophosphohydrolase (ATPPPH) and neutral inorganic pyrophosphatase activities were assayed in synovial fluids (SF) from 37 patients with a variety of arthropathies. ATPPPH activity was detected in all fluids, but was highest in patients with chronic chondrocalcinosis; its activity in patients with osteoarthritis was higher than that in patients with rheumatoid arthritis, gout, or pseudogout. ATPPPH activity correlated positively with SF pyrophosphate concentration and negatively with SF white blood cell count. Pyrophosphatase activity did not correlate with diagnosis, pyrophosphate level, or white blood cell count.
Author List
Rachow JW, Ryan LMMESH terms used to index this publication - Major topics in bold
Adenosine TriphosphatasesAdult
Aged
Calcinosis
Calcium Pyrophosphate
Chondrocalcinosis
Crystallization
Diphosphates
Female
Humans
Male
Middle Aged
Osteoarthritis
Pyrophosphatases
Synovial Fluid
