Glomerulonephritis in childhood. Curr Opin Pediatr 1997 Apr;9(2):154-9
Date
04/01/1997Pubmed ID
9204243DOI
10.1097/00008480-199704000-00007Scopus ID
2-s2.0-0030928403 (requires institutional sign-in at Scopus site) 13 CitationsAbstract
Safer renal biopsy techniques have led to increased recognition of the various forms of glomerulonephritis in the pediatric population. Our understanding of their natural history and progression has improved, and we now know that there is significant morbidity associated with diseases such as IgA nephropathy and membranoproliferative glomerulonephritis. Knowledge of the pathophysiology of progressive renal disease has also expanded, but specific treatment modalities, especially for children, are lacking and continue to be areas for future clinical research. This article reviews four types of glomerulonephritis that occur in childhood: acute poststreptococcal glomerulonephritis, IgA nephropathy, Alport's syndrome, and membranoproliferative glomerulonephritis. The clinical and pathologic features of each are reviewed, and the current literature covering new developments in their prognosis, genetics, or therapies are summarized.
Author List
Pan CGAuthor
Cynthia G. Pan MD Adjunct Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Acute DiseaseChild
Glomerulonephritis
Glomerulonephritis, IGA
Glomerulonephritis, Membranoproliferative
Humans
Nephritis, Hereditary