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Pharyngeal pH monitoring in patients with posterior laryngitis. Otolaryngol Head Neck Surg 1999 May;120(5):672-7

Date

05/06/1999

Pubmed ID

10229591

DOI

10.1053/hn.1999.v120.a91774

Scopus ID

2-s2.0-0032932307 (requires institutional sign-in at Scopus site)   99 Citations

Abstract

OBJECTIVE: To evaluate the diagnostic value of 3-site 24-hour ambulatory pH monitoring in patients with posterior laryngitis (PL) and the prevalence of esophageal abnormalities in this patient group.

METHODS: Twenty patients with PL and 17 healthy volunteers were studied as controls. Control subjects had transnasal esophagogastroduodenoscopy (T-EGD) and ambulatory pH monitoring. Patients underwent T-EGD, ambulatory pH monitoring, and barium esophagram.

RESULTS: T-EGD documented no abnormality in controls. Esophagitis was present in 2 PL patients, and hiatal hernia in 3. Ambulatory pH monitoring showed that 15 PL patients and 2 controls exhibited pharyngeal acid reflux. Barium esophagram documented gastroesophageal reflux in 5 PL patients. However, none of these barium reflux events reached the pharynx. All PL patients with barium esophagram evidence of gastroesophageal reflux also showed pharyngeal acid reflux by pH monitoring.

CONCLUSION: Pharyngeal acid reflux is more prevalent in patients with PL than in healthy controls. Patients with PL infrequently have esophageal sequelae of reflux disease. Ambulatory 24-hour simultaneous 3-site pharyngoesophageal pH monitoring detects gastroesophagopharyngeal acid reflux events in most patients with PL.

Author List

Ulualp SO, Toohill RJ, Hoffmann R, Shaker R

Author

Reza Shaker MD Assoc Provost, Sr Assoc Dean, Ctr Dir, Chief, Prof in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Aged
Aged, 80 and over
Barium Sulfate
Case-Control Studies
Endoscopy, Digestive System
Female
Gastroesophageal Reflux
Humans
Hydrogen-Ion Concentration
Laryngitis
Male
Middle Aged
Monitoring, Ambulatory
Pharynx
Prevalence
Reproducibility of Results