Evidence for using chlorhexidine gluconate preoperative cleansing to reduce the risk of surgical site infection. AORN J 2010 Nov;92(5):509-18
Date
11/03/2010Pubmed ID
21040815DOI
10.1016/j.aorn.2010.01.020Scopus ID
2-s2.0-78049241602 (requires institutional sign-in at Scopus site) 72 CitationsAbstract
Surgical site infections are associated with significant patient morbidity and mortality and are the third most frequently reported health care-associated infection. A suggested risk reduction strategy has been the preadmission shower or skin cleansing with chlorhexidine gluconate (CHG). Although older clinical trials question the clinical efficacy of cleansing with CHG, recent evidence-based scientific and clinical studies support two types of CHG application (ie, a 2% CHG-coated cloth or 4% CHG soap) using a standardized, timed process before hospital admission as an effective strategy for reducing the risk of postoperative surgical site infection.
Author List
Edmiston CE Jr, Okoli O, Graham MB, Sinski S, Seabrook GRAuthor
Mary Beth Graham MD Associate Chief, Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Anti-Infective Agents, LocalChlorhexidine
Evidence-Based Medicine
Humans
Preoperative Care
Risk Factors
Safety Management
Surgical Wound Infection
Treatment Outcome