Faculty Collaboration Database

Peripheral mechanisms affecting the lower esophageal sphincter tone. Gastroenterol Clin North Am 2002 Dec;31(4 Suppl):S21-33

Date

12/20/2002

Pubmed ID

12489468

DOI

10.1016/s0889-8553(02)00061-4

Scopus ID

2-s2.0-0036897274 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

LES tone is influenced by central and peripheral mechanisms. Peripheral factors influencing the LES tone include inhibitory reflexes originating from the stomach, esophagus, pharynx, and larynx. Although the role of LES relaxation and its associated reflux events induced by gastric distention has been extensively studied, the LES relaxations triggered by stimulation of the aerodigestive tract have only recently been the focus of systematic investigation and have resulted in documentation of the intricate reflex relationship between the upper gastrointestinal tract and the aerodigestive tract.

Author List

Gawrieh S, Shaker R

Author

Reza Shaker MD Assoc Provost, Sr Assoc Dean, Ctr Dir, Chief, Prof in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Animals
Diaphragm
Esophagogastric Junction
Esophagus
Humans
Larynx
Muscle Tonus
Pharynx
Reflex
Stomach