Successful treatment of tumor-induced osteomalacia with CT-guided percutaneous ethanol and cryoablation. J Clin Endocrinol Metab 2012 Oct;97(10):3421-5
Date
07/28/2012Pubmed ID
22837186DOI
10.1210/jc.2012-1719Scopus ID
2-s2.0-84867244983 (requires institutional sign-in at Scopus site) 30 CitationsAbstract
CONTEXT: Tumor-induced osteomalacia is a rare condition usually caused by benign mesenchymal tumors. When the tumor can be found, patients are usually managed by wide excision of the tumor.
OBJECTIVE: We report a 51-yr-old male with clinical and biochemical evidence of tumor-induced osteomalacia caused by a mesenchymal tumor in the right iliac bone. He declined surgery and appears to have been successfully managed by computed tomography-guided percutaneous ethanol ablation and percutaneous cryoablation.
RESULTS: Our patient appears to have had an excellent clinical and biochemical response to computed tomography-guided percutaneous ethanol ablation and percutaneous cryoablation. We found one prior case of image-guided ablation using radiofrequency ablation for tumor-induced osteomalacia.
CONCLUSIONS: Although the standard treatment for tumor-induced osteomalacia is wide excision of the tumor, image-guided ablation may be an option in patients who cannot have appropriate surgery or who decline surgery.
Author List
Tutton S, Olson E, King D, Shaker JLAuthors
David M. King MD Chair, Professor in the Orthopaedic Surgery department at Medical College of WisconsinJoseph L. Shaker MD Professor in the Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
CryosurgeryEthanol
Humans
Male
Mesenchymoma
Middle Aged
Neoplasms, Connective Tissue
Osteomalacia
Solvents
Tomography, X-Ray Computed
