Faculty Collaboration Database

Exploring genetic, genomic, and phenotypic data at the rat genome database. Curr Protoc Bioinformatics 2012 Dec;Chapter 1:1.14.1-1.14.27

Date

12/21/2012

Pubmed ID

23255149

Pubmed Central ID

PMC3555435

DOI

10.1002/0471250953.bi0114s40

Scopus ID

2-s2.0-84875531338 (requires institutional sign-in at Scopus site)   10 Citations

Abstract

The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human physiology and disease. The Rat Genome Database (RGD, http://rgd.mcw.edu) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes, and cellular components for genes, quantitative trait loci, and strains. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat.

Author List

Laulederkind SJF, Hayman GT, Wang SJ, Lowry TF, Nigam R, Petri V, Smith JR, Dwinell MR, Jacob HJ, Shimoyama M

Authors

Melinda R. Dwinell PhD Professor in the Physiology department at Medical College of Wisconsin
G. Thomas Hayman PhD Research Scientist II in the Physiology department at Medical College of Wisconsin
Stanley J. Laulederkind Research Scientist II in the Physiology department at Medical College of Wisconsin
Shur-Jen Wang Research Scientist II in the Physiology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Animals
Databases, Genetic
Genome
Genomics
Phenotype
Quantitative Trait Loci
Rats