Faculty Collaboration Database

1. Strack A, Duffy CF, Malvey M, Arriaga EA. Individual mitochondrion characterization: a comparison of classical assays to capillary electrophoresis with laser-induced fluorescence detection. Anal Biochem. PubMed PMID: 11444809.

2. Eskra L, Mathison A, Splitter G. Microarray analysis of mRNA levels from RAW264.7 macrophages infected with Brucella abortus. Infect Immun. 2003 Mar;71(3):1125-33. PMCID: PMC148819

3. Rajashekara G, Krepps M, Eskra L, Mathison A, Montgomery A, Ishii Y, Splitter G. Unraveling Brucella genomics and pathogenesis in immunocompromised IRF-1-/- mice. Am J Reprod Immunol. 2005 Dec;54(6):358-68.

4. Rajashekara G, Eskra L, Mathison A, Petersen E, Yu Q, Harms J, Splitter G. Brucella: functional genomics and host-pathogen interactions. Anim Health Res Rev. 2006;7(1-2):1-11.

5. Lomberk G, Mathison AJ, Grzenda A, Urrutia R. The sunset of somatic genetics and the dawn of epigenetics: a new frontier in pancreatic cancer research. Curr Opin Gastroenterol. 2008 Sep;24(5):597-602. PMCID: PMC2941574

6. Covert J, Mathison AJ, Eskra L, Banai M, Splitter G. Brucella melitensis, B. neotomae and B. ovis elicit common and distinctive macrophage defense transcriptional responses. Exp Biol Med (Maywood). 2009 Dec;234(12):1450-67. PMCID: PMC2880867

7. Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R. Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes. Pancreatology. 2010;10(4):505-16. PMCID: PMC3214918

8. Daftary GS, Lomberk GA, Buttar NS, Allen TW, Grzenda A, Zhang J, Zheng Y, Mathison AJ, Gada RP, Calvo E, Iovanna JL, Billadeau DD, Prendergast FG, Urrutia R. Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology. J Biol Chem. 2012 Mar 02;287(10):7010-25. PMCID: PMC3293586

9. Seo S, Lomberk G, Mathison A, Buttar N, Podratz J, Calvo E, Iovanna J, Brimijoin S, Windebank A, Urrutia R. Krüppel-like factor 11 differentially couples to histone acetyltransferase and histone methyltransferase chromatin remodeling pathways to transcriptionally regulate dopamine D2 receptor in neuronal cells. J Biol Chem. 2012 Apr 13;287(16):12723-35. PMCID: PMC3339994

10. Lomberk G, Mathison AJ, Grzenda A, Seo S, DeMars CJ, Ilyas SI, Bonilla-Velez J, Calvo E, Fernandez-Zapico ME, Iovanna J, Buttar NS, Urrutia R. Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases. J Biol Chem. 2012 Apr 13;287(16):13026-39. PMCID: PMC3339955

11. Grzenda A, Lomberk G, Svingen P, Mathison A, Calvo E, Iovanna J, Xiong Y, Faubion W, Urrutia R. Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression. Epigenetics Chromatin. 2013 Feb 28;6(1):3. PMCID: PMC3606351

12. Daftary GS, Zheng Y, Tabbaa ZM, Schoolmeester JK, Gada RP, Grzenda AL, Mathison AJ, Keeney GL, Lomberk GA, Urrutia R. A novel role of the Sp/KLF transcription factor KLF11 in arresting progression of endometriosis. PLoS One. 2013;8(3):e60165. PMCID: PMC3610699

13. Lomberk G, Grzenda A, Mathison A, Escande C, Zhang JS, Calvo E, Miller LJ, Iovanna J, Chini EN, Fernandez-Zapico ME, Urrutia R. Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young. J Biol Chem. 2013 Jun 14;288(24):17745-58. PMCID: PMC3682574

14. Grzenda A, Leonard P, Seo S, Mathison AJ, Urrutia G, Calvo E, Iovanna J, Urrutia R, Lomberk G. Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression. Epigenetics Chromatin. 2013 Jul 05;6(1):21. PMCID: PMC3707784

15. Mathison A, Grzenda A, Lomberk G, Velez G, Buttar N, Tietz P, Hendrickson H, Liebl A, Xiong YY, Gores G, Fernandez-Zapico M, Larusso NF, Faubion W, Shah VH, Urrutia R. Role for Krüppel-like transcription factor 11 in mesenchymal cell function and fibrosis. PLoS One. 2013;8(9):e75311. PMCID: PMC3775729

16. Hayashi Y, Asuzu DT, Gibbons SJ, Aarsvold KH, Bardsley MR, Lomberk GA, Mathison AJ, Kendrick ML, Shen KR, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Farrugia G, Urrutia RA, Ordog T. Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways. PLoS One. 2013;8(10):e76822. PMCID: PMC3792098

17. Calvo E, Grzenda A, Lomberk G, Mathison A, Iovanna J, Urrutia R. Single and combinatorial chromatin coupling events underlies the function of transcript factor Krüppel-like factor 11 in the regulation of gene networks. BMC Mol Biol. 2014 May 25;15:10. PMCID: PMC4049485

18. de Assuncao TM, Lomberk G, Cao S, Yaqoob U, Mathison A, Simonetto DA, Huebert RC, Urrutia RA, Shah VH. New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. J Biol Chem. 2014 May 30;289(22):15798-809. PMCID: PMC4140934

19. Escande C, Nin V, Pirtskhalava T, Chini CC, Thereza Barbosa M, Mathison A, Urrutia R, Tchkonia T, Kirkland JL, Chini EN. Deleted in Breast Cancer 1 regulates cellular senescence during obesity. Aging Cell. 2014 Oct;13(5):951-3. PMCID: PMC4172532

20. Loft A, Forss I, Siersbæk MS, Schmidt SF, Larsen AS, Madsen JG, Pisani DF, Nielsen R, Aagaard MM, Mathison A, Neville MJ, Urrutia R, Karpe F, Amri EZ, Mandrup S. Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers. Genes Dev. 2015 Jan 01;29(1):7-22. PMCID: PMC4281566

21. Leonard PH, Grzenda A, Mathison A, Morbeck DE, Fredrickson JR, de Assuncao TM, Christensen T, Salisbury J, Calvo E, Iovanna J, Coddington CC, Urrutia R, Lomberk G. The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage. BMC Dev Biol. 2015 May 29;15:23. PMCID: PMC4448908

22. Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE. Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. J Clin Invest. 2015 Oct 01;125(10):3819-30. PMCID: PMC4607137

23. Mathison A, Escande C, Calvo E, Seo S, White T, Salmonson A, Faubion WA Jr, Buttar N, Iovanna J, Lomberk G, Chini EN, Urrutia R. Phenotypic Characterization of Mice Carrying Homozygous Deletion of KLF11, a Gene in Which Mutations Cause Human Neonatal and MODY VII Diabetes. Endocrinology. 2015 Oct;156(10):3581-95. PMCID: PMC4588811

24. Campoy EM, Laurito SR, Branham MT, Urrutia G, Mathison A, Gago F, Orozco J, Urrutia R, Mayorga LS, Roqué M. Asymmetric Cancer Hallmarks in Breast Tumors on Different Sides of the Body. PLoS One. 2016;11(7):e0157416. PMCID: PMC4934783

25. Sarmento OF, Svingen PA, Xiong Y, Sun Z, Bamidele AO, Mathison AJ, Smyrk TC, Nair AA, Gonzalez MM, Sagstetter MR, Baheti S, McGovern DP, Friton JJ, Papadakis KA, Gautam G, Xavier RJ, Urrutia RA, Faubion WA. The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD). J Biol Chem. 2017 Jan 13;292(2):706-722. PMCID: PMC5241744

26. Cousin MA, Zimmermann MT, Mathison AJ, Blackburn PR, Boczek NJ, Oliver GR, Lomberk GA, Urrutia RA, Deyle DR, Klee EW. Functional validation reveals the novel missense V419L variant in <i>TGFBR2</i> associated with Loeys-Dietz syndrome (LDS) impairs canonical TGF-β signaling. Cold Spring Harb Mol Case Stud. 2017 Jul;3(4). PMCID: PMC5495030

27. Mathison A, Salmonson A, Missfeldt M, Bintz J, Williams M, Kossak S, Nair A, de Assuncao TM, Christensen T, Buttar N, Iovanna J, Huebert R, Lomberk G. Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe. Mol Cancer Res. 2017 Aug;15(8):984-997. PMCID: PMC5705946

28. Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, Klee E, Moutardier V, Gayet O, Bian B, Duconseil P, Gilabert M, Bigonnet M, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Secq V, De Reyniès A, Dusetti N, Iovanna J, Urrutia R. Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes. Nat Commun. 2018 May 17;9(1):1978. PMCID: PMC5958058

29. Seo S, Mathison A, Grzenda A, Podratz J, Calvo E, Brimijoin S, Windebank A, Iovanna J, Lomberk G, Urrutia R. Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway. Sci Rep. 2018 Oct 10;8(1):15077. PMCID: PMC6180112

30. Martin-Mateos R, De Assuncao TM, Arab JP, Jalan-Sakrikar N, Yaqoob U, Greuter T, Verma VK, Mathison AJ, Cao S, Lomberk G, Mathurin P, Urrutia R, Huebert RC, Shah VH. Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis. Cell Mol Gastroenterol Hepatol. 2019;7(1):197-209. PMCID: PMC6282644

31. Williams MM, Mathison AJ, Christensen T, Greipp PT, Knutson DL, Klee EW, Zimmermann MT, Iovanna J, Lomberk GA, Urrutia RA. Aurora kinase B-phosphorylated HP1α functions in chromosomal instability. Cell Cycle. 2019 Jun;18(12):1407-1421. PMCID: PMC6592258

32. He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG. SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23534-23541. PMCID: PMC6876149

33. Mathison A, Milech De Assuncao T, Dsouza NR, Williams M, Zimmermann MT, Urrutia R, Lomberk G. Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain. PLoS One. 2020;15(2):e0217452. PMCID: PMC7004349

34. Urrutia G, Salmonson A, Toro-Zapata J, de Assuncao TM, Mathison A, Dusetti N, Iovanna J, Urrutia R, Lomberk G. Combined Targeting of G9a and Checkpoint Kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse. Mol Cancer Res. 2020 Mar;18(3):448-462. PMCID: PMC7056528

35. Danes JM, de Abreu ALP, Kerketta R, Huang Y, Palma FR, Gantner BN, Mathison AJ, Urrutia RA, Bonini MG. Inorganic arsenic promotes luminal to basal transition and metastasis of breast cancer. FASEB J. 2020 Dec;34(12):16034-16048. PMCID: PMC8289339

36. Chi YI, Stodola TJ, De Assuncao TM, Leverence EN, Tripathi S, Dsouza NR, Mathison AJ, Basel DG, Volkman BF, Smith BC, Lomberk G, Zimmermann MT, Urrutia R. Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction. Orphanet J Rare Dis. 2021 Feb 05;16(1):66. PMCID: PMC7866879

37. Zimmermann MT, Mathison AJ, Stodola T, Evans DB, Abrudan JL, Demos W, Tschannen M, Aldakkak M, Geurts J, Lomberk G, Tsai S, Urrutia R. Interpreting Sequence Variation in PDAC-Predisposing Genes Using a Multi-Tier Annotation Approach Performed at the Gene, Patient, and Cohort Level. Front Oncol. 2021;11:606820. PMCID: PMC7973372

38. Gonzalez MM, Bamidele AO, Svingen PA, Sagstetter MR, Smyrk TC, Gaballa JM, Hamdan FH, Kosinsky RL, Gibbons HR, Sun Z, Ye Z, Nair A, Ramos GP, Braga Neto MB, Wixom AQ, Mathison AJ, Johnsen SA, Urrutia R, Faubion WA Jr. BMI1 maintains the Treg epigenomic landscape to prevent inflammatory bowel disease. J Clin Invest. 2021 Jun 15;131(12). PMCID: PMC8203461

39. Urrutia G, de Assuncao TM, Mathison AJ, Salmonson A, Kerketta R, Zeighami A, Stodola TJ, Adsay V, Pehlivanoglu B, Dwinell MB, Zimmermann MT, Iovanna JL, Urrutia R, Lomberk G. Inactivation of the Euchromatic Histone-Lysine <i>N</i>-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks. Front Cell Dev Biol. 2021;9:681153. PMCID: PMC8261250

40. Mathison AJ, Kerketta R, de Assuncao TM, Leverence E, Zeighami A, Urrutia G, Stodola TJ, di Magliano MP, Iovanna JL, Zimmermann MT, Lomberk G, Urrutia R. Kras^G12D induces changes in chromatin territories that differentially impact early nuclear reprogramming in pancreatic cells. Genome Biol. 2021 Oct 14;22(1):289. PMCID: PMC8518179

41. Stabenau KA, Zimmermann MT, Mathison A, Zeighami A, Samuels TL, Chun RH, Papsin BC, McCormick ME, Johnston N, Kerschner JE. RNA Sequencing and Pathways Analyses of Middle Ear Epithelia From Patients With Otitis Media. Laryngoscope. 2021 Nov;131(11):2590-2597.

42. Stodola TJ, Chi YI, De Assuncao TM, Leverence EN, Tripathi S, Dsouza NR, Mathison AJ, Volkman BF, Smith BC, Lomberk G, Zimmermann MT, Urrutia R. Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1-like (DOT1L) and partnering complexes involved in leukemogenesis. Proteins. 2022 Jan;90(1):282-298. PMCID: PMC8671179

43. Tripathi S, Dsouza NR, Mathison AJ, Leverence E, Urrutia R, Zimmermann MT. Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics. Comput Struct Biotechnol J. 2022;20:117-127. PMCID: PMC8688876

44. Allison RL, Adelman JW, Abrudan J, Urrutia RA, Zimmermann MT, Mathison AJ, Ebert AD. Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons. Genes (Basel). 2022 Jan 27;13(2). PMCID: PMC8871895

45. Xie Y, Nishijima Y, Zinkevich NS, Korishettar A, Fang J, Mathison AJ, Zimmermann MT, Wilcox DA, Gutterman DD, Shen Y, Zhang DX. NADPH oxidase 4 contributes to TRPV4-mediated endothelium-dependent vasodilation in human arterioles by regulating protein phosphorylation of TRPV4 channels. Basic Res Cardiol. 2022 Apr 25;117(1):24. PMCID: PMC9119129

46. Chi YI, Stodola TJ, De Assuncao TM, Leverence EN, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R. Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers. Comput Struct Biotechnol J. 2022;20:2200-2211. PMCID: PMC9111933

47. Fang S, Wu J, Reho JJ, Lu KT, Brozoski DT, Kumar G, Werthman AM, Silva SD Jr, Muskus Veitia PC, Wackman KK, Mathison AJ, Teng BQ, Lin CW, Quelle FW, Sigmund CD. RhoBTB1 reverses established arterial stiffness in angiotensin II-induced hypertension by promoting actin depolymerization. JCI Insight. 2022 May 09;7(9). PMCID: PMC9090250

48. Stancill JS, Hansen PA, Mathison AJ, Schmidt EE, Corbett JA. Deletion of Thioredoxin Reductase Disrupts Redox Homeostasis and Impairs β-Cell Function. Function (Oxf). 2022;3(4):zqac034. PMCID: PMC9301323

49. Stabenau KA, Samuels TL, Lam TK, Mathison AJ, Wells C, Altman KW, Battle MA, Johnston N. Pepsinogen/Proton Pump Co-Expression in Barrett's Esophageal Cells Induces Cancer-Associated Changes. Laryngoscope. 2023 Jan;133(1):59-69.

50. Han L, Wu Y, Fang K, Sweeney S, Roesner UK, Parrish M, Patel K, Walter T, Piermattei J, Trimboli A, Lefler J, Timmers CD, Yu XZ, Jin VX, Zimmermann MT, Mathison AJ, Urrutia R, Ostrowski MC, Leone G. The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis. Nat Commun. 2023 Jan 03;14(1):1. PMCID: PMC9810714

51. Kim J, Zimmerman MA, Shin WY, Boettcher BT, Lee JS, Park JI, Ali M, Yang M, Mishra J, Hagen CE, McGraw JE, Mathison A, Woehlck HJ, Lomberk G, Camara AKS, Urrutia RA, Stowe DF, Hong JC. Effects of Subnormothermic Regulated Hepatic Reperfusion on Mitochondrial and Transcriptomic Profiles in a Porcine Model. Ann Surg. 2023 Feb 01;277(2):e366-e375. PMCID: PMC8840998

52. Ratnasinghe BD, Haque N, Wagenknecht JB, Jensen DR, Valdivia Esparza GK, Leverence EN, Milech De Assuncao T, Mathison AJ, Lomberk G, Smith BC, Volkman BF, Urrutia R, Zimmermann MT. Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape. Comput Struct Biotechnol J. 2023;21:4790-4803. PMCID: PMC10570560

53. Kleman A, Singavi A, Pommert L, Mathison AJ, Hari P, Dhakal B, Mohan M, Janz S, Knight JM, Shah MV, Schinke C, Burns R, Steinhardt GF, Rao S, Carlson K. A timeline of genetic variant enrichment: from multiple myeloma diagnosis to myeloma-associated myeloid malignancy. Blood Adv. 2023 Sep 26;7(18):5549-5553. PMCID: PMC10514068

54. Chi YI, Jorge SD, Jensen DR, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R. A multi-layered computational structural genomics approach enhances domain-specific interpretation of Kleefstra syndrome variants in EHMT1. Comput Struct Biotechnol J. 2023;21:5249-5258. PMCID: PMC10632586

55. Jorge SD, Chi YI, Mazaba JL, Haque N, Wagenknecht J, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R. Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction. Front Genet. 2023;14:1291307. PMCID: PMC10715303

56. Pisano MD, Sun F, Cheng Y, Parashar D, Zhou V, Jing X, Sompallae R, Abrudan J, Zimmermann MT, Mathison A, Janz S, Pufall MA. IL6Myc mouse is an immunocompetent model for the development of aggressive multiple myeloma. Haematologica. 2023 Dec 01;108(12):3372-3383. PMCID: PMC10690922

57. Zhou W, Lim A, Elmadbouh OHM, Edderkaoui M, Osipov A, Mathison AJ, Urrutia R, Liu T, Wang Q, Pandol SJ. Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells. Free Radic Biol Med. 2024 Feb 20;212:493-504. PMCID: PMC10906657

58. Hall WA, Mathison AJ, DeVoe E, Tschannen M, Wendt-Andrae J, Straza M, Awan M, Puckett LL, Lawton CAF, Schultz C, Urrutia R, Kerns S, Torres-Roca JF, Li XA, Erickson B, Nevalainen MT, Zimmermann MT, Paulson E. Changes in Daily Apparent Diffusion Coefficient on Fully Quantitative Magnetic Resonance Imaging Correlate With Established Genomic Pathways of Radiation Sensitivity and Reveal Novel Biologic Associations. Int J Radiat Oncol Biol Phys. 2024 Oct 01;120(2):570-578.

59. Kim J, Zimmermann MT, Mathison AJ, Lomberk G, Urrutia R, Hong JC. Transcriptional Profiling Underscores the Role of Preprocurement Allograft Metabolism and Innate Immune Status on Outcomes in Human Liver Transplantation. Ann Surg Open. 2024 Jun;5(2):e444. PMCID: PMC11191965

60. Pollin G, Mathison AJ, de Assuncao TM, Thomas A, Zeighami A, Salmonson A, Liu H, Urrutia G, Vankayala P, Pandol SJ, Hong JC, Zimmermann MT, Iovanna J, Jin VX, Urrutia R, Lomberk G. <i>Ehmt2</i> inactivation in pancreatic epithelial cells shapes the transcriptional landscape and inflammation response of the whole pancreas. Front Genet. 2024;15:1412767. PMCID: PMC11211573

61. Zenga J, Awan MJ, Frei A, Massey B, Bruening J, Shukla M, Sharma GP, Shreenivas A, Wong SJ, Zimmermann MT, Mathison AJ, Himburg HA. Type I interferon signaling promotes radioresistance in head and neck cancer. Transl Cancer Res. 2024 May 31;13(5):2535-2543. PMCID: PMC11170510

62. Zenga J, Himburg HA, Wong SJ, Kearl T, Hematti P, Jin VX, Memon AA, Mathison AJ, Awan MJ. In silico identification of public neo-antigens in head and neck Cancer for T cell receptor Engineering: Targeting PI3KCA and TP53 missense mutations. Oral Oncol. 2024 Sep;156:106947.

63. Pollin G, Lomberk GA, Mathison AJ, Zimmermann MT, Urrutia R. Mutant KRAS inhibitors enter the scene of precision therapeutics for pancreatic cancer. J Gastrointest Oncol. 2024 Aug 31;15(4):1996-2001. PMCID: PMC11399826

64. Ergun P, Samuels TL, Mathison AJ, Plehhova K, Coyle C, Horvath L, Johnston N. Global Transcriptomic Analysis of Topical Sodium Alginate Protection against Peptic Damage in an In Vitro Model of Treatment-Resistant Gastroesophageal Reflux Disease. Int J Mol Sci. 2024 Oct 05;25(19). PMCID: PMC11605242

65. Khedr S, Dissanayake LV, Alsheikh AJ, Zietara A, Spires DR, Kerketta R, Mathison AJ, Urrutia R, Palygin O, Staruschenko A. Role of cGAS-STING pathway in aging and sexual dimorphism in diabetic kidney disease. JCI Insight. 2024 Nov 26.

1. Great Lakes Regional Center of Excellence Meeting, Zion, IL. November 2004. A Mathison, L Eskra, G Splitter. Macrophage transcript levels altered by Brucella infection reveal host mechanisms specific to pathogenic B. melitensis.

2. Immunology Research Symposium, Madison, WI. June 2006. A Mathison, L Eskra, G Splitter. Macrophage transcript levels altered by Brucella infection reveal host mechanisms specific to pathogenic B. melitensis.

3. American Pancreatic Association Annual Meeting, 2008. G Lomberk, S Ilyas, A Mathison, J Bonilla, A Conde Perez, Demars, N Buttar, and R Urrutia. KLF11 complexes with the epigenetic gene silencer protein, HP1 to mediate tumor suppressor activities.

4. European Pancreatic Club Meeting, 2009. G. Lomberk, A Mathison, M Fernandez-Zapico, S Ilyas, C Demars, N Buttar, R Urrutia. KLF11 complexes with the epigenetic gene silencer protein, HP1 to mediate its tumor suppressor activities

5. American Pancreatic Association Annual Meeting, 2009. A Liebl, A Mathison, J Bharrucha, V Shah, G Lomberk, R Urrutia. Generation of human, mouse, and rat pancreatic stellate cell lines for studying transcriptional control of extra cellular matrix synthesis

6. American Pancreatic Association Annual Meeting, 2009. A Mathison, A Liebl, V Shah, G Lomberk and R Urrutia. Role of the KLF11-MMP pathway in stellate cell biology and tumor suppression.

7. Digestive Disease Week Meeting, 2010. C Virk, A Mathison, C DeMars, U Shergill, G Lomberk S Sodavarapu, M Fernandez-Zapico, U Yaqoob, V Shah, R Urrutia, N Buttar. Distinct Stellate Cell Response to Injury in KLF11 Knockout Mice: Implications in Repair and Organ Dysfunction.

8. American Pancreatic Association Annual Meeting, 2010. A Mathison, A Liebl, CJ DeMars, U Shergill, G Lomberk, V Shah, N Buttar and R Urrutia. Novel Tumor Suppresor Pathway in Pancreatic Cancer Derived from Selective Remodeling of Desmoplasia.

9. American Pancreatic Association Annual Meeting, 2011. A Mathison, A Liebl, J Bharrucha, V Shah, G Lomberk, R Urrutia. Epigenetics in GI Organ Fibrosis: Generation of Mouse and Rat Pancreatic Stellate Cell Lines for Studying Epigenetic Control of Extracellular Matrix Synthesis

10. American Pancreatic Association Annual Meeting, 2011. A Mathison, A Liebl, G Lomberk, CJ DeMars, U Shergill, V Shah, N Buttar, R Urrutia. Epigenetics in GI Organ Fibrosis: A KLF11-HDAC Mediated Pathway is Anti-fibrogenic in Liver and Pancreas.

11. American Pancreatic Association Annual Meeting, 2013. G Lomberk, A Mathison, and R Urrutia. Epigenetic Signaling by HP1 Regulates KRAS-Induced Growth Promoting Gene Networks in Pancreatic Cancer Cells.

12. American Pancreatic Association Annual Meeting, 2013. A Mathison, M Fernandez- Zapico, R Urrutia and G Lomberk. Preclinical Testing of a New Combinatorial Therapy Against Aurora A and G9a for the Treatment of Pancreatic Cancer.

13. Midwest Chromatin and Epigenetics Meeting, 2014. Differential Regulation of HP1 Isoforms by Aurora Kinases during Mitosis. M Williams, A Mathison, G Lomberk and R Urrutia.

14. American Pancreatic Association Annual Meeting, 2014. HP1-Histone Methyl Transferase Pathways Relay Epigenetic Signals Downstream of the Pancreatic Oncogenes, Aurora Kinases. M Williams, A Mathison, G Lomberk and R Urrutia.

15. American Pancreatic Association Annual Meeting, 2014. Inactivation of the AurkA-HP1γ-G9a Pathway Synergistically Inhibits PDAC Cell Growth by Triggering Cell Death via Mitotic Catastrophe. A Mathison, M Williams, R Urrutia, G Lomberk.

16. American Association for Cancer Research, 2017. Pharmacological targeting of the Aurora A and Histone 3 lysine 9 methyltransferase pathways in pancreatic cancer induces mitotic catastrophe. A. Mathison, A. Salmonson, M. Missfeldt, T. de Assuncao, J. Bintz, T. Christensen, S. Kossak, A. Nair, J. Iovanna, R. Huebert, G. Lomberk.

17. American Association for Cancer Research, 2017. The epigenetic regulator, G9a, is a KRAS-inducible protein and its inactivation inhibits PanIN formation by this oncogene. A. Mathison, A. Salmonson, B. Paradise, M. Missfeldt, J. Iovanna, D. Billadeau, R. Urrutia, G. Lomberk.

18. Academic Surgical Congress, 2019. The Early Epigenomic Landscape of Oncogenic KRAS Signaling. R. Kerketta, A. Mathison, A. Zeighami, J. Abrudan, W. Demos, M. Zimmermann, G. Lomberk, R. Urrutia.

19. American Association for Cancer Research, 2019. Genomic variation in PDAC-predisposing genes identified using the MCW germline exome panel. J Abrudan, S Tsai, W Demos, M.T. Zimmermann, M Tschannen, J Geurts, A Mathison, G Lomberk, D Evans, R Urrutia.

20. American Society of Human Genetics, 2020. Interpreting the wide genomic variation in PDAC predisposing genes. A. Mathison, M.T. Zimmermann, J.L. Abrudan, T. Stodola, W. Demos, M. Tschannen, M. Aldakkak, J. Geurts, S. Tsai, G. Lomberk, D. Evans, and R. Urrutia.

21. Experimental Biology, 2022. Rho-related BTB Domain-containing Protein 1 Reverses Established Arterial Stiffness in Angiotensin II-treated Mice. S. Fang, J. Wu, J. Reho, K. Lu, D. Brozoski, A. Werthman, G. Kumar, S. Silva, P. Muskus, K. Wackman, A. Mathison, R. Urrutia, B. Teng, C. Lin, F. Quelle, C. Sigmund

22. Experimental Biology, 2022. To ChIP, or to CUT, that is the question: Comparative Evaluation of NextGen Methodologies for Studying the genome-wide distribution of Histone H3 Lysine 9 di-methyl mark in pancreatic cells. G. Urrutia, J. Abrudan, M. Du, T. de Assuncao, A. Mathison, M. Zimmermann, G. Lomberk, R. Urrutia

23. Experimental Biology, 2022. Defining the Mutational Landscape That Affects the Histone Demethylase KDM6A/UTX in Human Cancer. Y. Chi, T. Stodola, T. de Assuncao, B. Volkman, B. Smith, A. Mathison, G. Lomberk, M. Zimmermann, R. Urrutia

24. Experimental Biology, 2022. Transcriptional Landscape Established by the Euchromatic Histone-lysine N-methyltransferase Pathway During Pancreas Ontogenesis and Pancreatitis. R. Urrutia, P. Vankayala, A. Salmonson, G. Urrutia, T. de Assuncao, M. Zimmermann, A. Mathison, G. Lomberk

25. Experimental Biology, 2022. Epigenomic mechanisms used by KrasG12D to regulate inflammatory gene clusters in epithelial pancreatic cancer cells, which are critical for reprogramming the tumor microenvironment. M. Du, J. Abrudan, G. Urrutia, T. de Assuncao, A. Mathison, M. Zimmermann, G. Lomberk, R. Urrutia

26. Experimental Biology, 2022. Integrative Modeling, Molecular Mechanics, and Molecular Dynamics Evaluation of Genomics Variants in KMT2C (MLL3), a Gene Involved in Kleefstra Syndrome Type 2. S. Jorge, Y. Chi, T. de Assuncao, A. Mathison, B. Volkman, B. Smith, G. Lomberk, M. Zimmermann, R. Urrutia

27. American Association for Cancer Research, 2022. The splanchnic mesenchyme is the main tissue origin of fibroblasts in the pancreas during homeostasis and tumorigenesis. L. Han, Y. Wu, M. Parrish, K. Patel, T. Trimboli, J. Lefler, X. Yu, M. Zimmermann, A. Mathison, R. Urrutia, M. Ostrowski, G. Leone

28. Society for Redox Biology and Medicine, 2022. Thioredoxin reductase 1 is required for maintenance of pancreatic beta-cell function and identity. J. Stancill, P. Hansen, A. Mathison, E. Schmidt, and J. Corbett

29. American Society for Pharmacology and Experimental Therapeutics, 2023. Exploring the Synergy of G9a and ATM/ATR Pathway Interactions as a Precision Treatment Strategy in ATM-deficient Pancreatic Ductal Adenocarcinoma. M. Dzikowski, G. Pollin, T. de Assuncao, V. Gunia, E. Leverence, A. Mathison, G. Lomberk.