CURRICULUM VITAE
Annette D. Segura MD
Annette D. Segura MD
Adjunct Assistant Professor
Department of Pathology
Division of Administration
Department of Pathology
Division of Administration
OFFICE ADDRESS: |
Children’s Wisconsin - Milwaukee Hospital |
8915 W Connell Court |
Milwaukee, WI 53226 |
Fax: 414-266-2779 |
Email: asegura@mcw.edu |
EDUCATION: |
- 1973 A.S. Biology, Sauk Valley College, Dixon, IL |
- 1975 BS Biology, University of Illinois at Champaign-Urbana, Urbana, IL |
- 1980 MD, University of Illinois-Rockford School of Medicine, Rockford, IL |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
07/1980 - 06/1984 Resident, Pathology, Medical College of Wisconsin, Milwaukee, WI |
02/1984 - 06/1984 Chief Resident, Pathology, Medical College of Wisconsin, Milwaukee, WI |
07/1984 - 06/1986 Fellow, Pathology, Pediatric, Medical College of Wisconsin, Milwaukee, WI |
FACULTY APPOINTMENTS: |
07/1988 - Present Assistant Professor, Pathology, Pediatric, Medical College of Wisconsin, Milwaukee, WI |
HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS: |
2000 - 2006 Technical Director-Surgical Pathology, Pathology, Pediatric, Children's Hospital of Wisconsin, Milwaukee, WI |
HOSPITAL STAFF PRIVILEGES: |
07/1986 - Present Pediatric Pathologist, Pathology and Laboratory Medicine, Pediatric, Children's Hospital of Wisconsin, Milwaukee, WI |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
Anatomic Pathology | 1988 | None |
Pediatric Pathology | 1999 | None |
Licensure | Number | Issue Date | Expiration |
State of Wisconsin: Medicine and Surgery | 23869-020 | 1981 | 2019 |
AWARDS AND HONORS: |
2008 - 2009 Outstanding Medical Student's Teachers, Medical College of Wisconsin |
2011 - 2012 Outstanding Medical Student Teachers, Medical College of Wisconsin |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
American Society of Clinical Pathologists |
Wisconsin Society of Pathologists |
Children's Oncology Group (Associate Member) |
Medical Society of Milwaukee County |
College of American Pathologists |
American Medical Association |
State Medical Society of Wisconsin |
Society for Pediatric Pathology |
United States and Canadian Academy of Pathology |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorial Board |
The Journal of the American Society of Ophthalmic Plastic and Reconstructive Surgery |
Pediatric Dermatology |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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COMMITTEE SERVICE: |
Medical College of Wisconsin |
1993 - 1996 Admissions Committee |
2002 LCME Task Force on Accreditation-Governance, Administration and Finance Subcommittee |
Hospital |
2009 - 2017 Alternate Departmental Representative, Medical Executive Committee, Children's Hospital of Wisconsin |
2016 - Present Member, Diagnostic Safety Committee, Children's Hospital of Wisconsin |
2017 - Present Member (Volunteer), Professional Review Committee, Medical Staff Office, Children's Hospital of Wisconsin |
MEDICAL COLLEGE TEACHING ACTIVITIES: |
Medical Student Education |
1986 - 1993 Sophomore Pathology Course-Laboratory Sessions: Congenital Cardiovascular Anomalies |
1987 - 1992 Sophomore Pathology Course - Tutorial Sessions |
1992 - Present Sophomore Pathology Course - Case-Based Learning Sessions: |
1995 - 2006 Lecturer - Renal Pathology: Sophomore Pathology |
1996 - 2006 Sophomore Pathology Course: Section Director: Renal Pathology |
2006 - Present Pediatric Surgical Pathology for M3/M4 Surgery Students |
2007 - 2012 Sophomore Pathology Course: Lecturer - Tumors of Infancy & Childhood |
2012 - Present M2 Discovery Curriculum: Content Expert for Renal Unit |
Resident and Fellow Education |
07/1986 - Present Resident Training in Pediatric Pathology |
1991 - 1995 Fellow Training in Pediatric Pathology |
2006 - 2009 Pediatric Surgical Pathology for PGY1 Surgery Residents: Introduction to Surgical Pathology |
2013 - Present M2 Discovery Curriculum: Laboratory Pathology of Kidney & Urinary Tract |
FACULTY DEVELOPMENT/CONTINUING MEDICAL EDUCATION: |
1986 - Present Tumor Board |
2001 - Present Surgical Pathology Conference |
2003 - Present Pediatric Renal Pathology Conference |
2003 - Present Pediatric Brain Tumor Conference |
2005 - Present Pediatric Multidisciplinary Conference |
2006 - Present Pediatric Dermatopathology Conference |
HOSPITAL CONFERENCES: |
Pediatric Morbidity-Mortality Conference |
Pediatric Renal Subspecialty |
Surgical Pathology Subspecialty |
Pediatric Brain Tumor Group |
Pediatric Dermatopathology Subspecialty |
Pediatric Tumor Board |
Pediatric Surgical Pathology Peer Review |
Pediatric Gastroenterology Subspecialty |
Pediatric Multidisciplinary Subspecialty |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Brimhall CL, Segura AD, McTigue K, Esterly NB. Nodular fasciitis on the palm of a child. Arch. Dermatol. 1989; 125:1441-1442. |
2. Tang TT, Segura AD, Oechler HW. Inflammatory myofibrohistiocytic proliferation simulating sarcoma in children. Cancer 1990; 65:1626-1634. |
3. Casale A, Sheth K, Leichter H, Segura A, Lawson R. Renal transplantation in a child with primary oxalosis. Child Nephrology and Urology, 1990; 10:103-106. |
4. Camitta B, Wells R, Segura A, Murray K, Dunn D. Osteoblastoma: Response to chemotherapy. Cancer 1990; 68:999-1003. |
5. Tang T, Oechler H, Hinke D, Segura A, Franciosi R. Limb body-wall complex in association with sirenomelia sequence ("Mermaid Syndrome"). American Journal of Medical Genetics 1991; 41:21-25. |
6. Tang T, Oechler H, Siker D, Segura A, Franciosi R. Anesthesia-induced Rhabdomyolysis in Infants with Unsuspected Duchenne Dystrophy. Acta Paediatrica Scandinavia 1992; Sep; 81(9):716-719. |
7. Whelan H, Traul D, Przybylski C, Segura A. Interactions of Merocyanine 540 with Human Brain Tumor Cells. Pediatr Neurol 1992; 82:117-120. |
8. Whelan H, Schmidt M, Anderson G, Chan B, Kubacki D, Segura A, Chitambar C. Antineoplastic Effects of Gallium Nitrate on Human Medulloblastoma In Vivo. Pediatr Neurol 1992; 8:323-327. |
9. Hansen K, Segura A, Esterly N. Solitary Congenital Nodule on the Ear of an Infant. Ped Derm 1993; 10:88-90. |
10. Whelan H, Schmidt M, Segura A, McAuliffe T, Bajic D, Murray K, Moulder J, Strother D, Thomas J, Meyer G. The role of photodynamic therapy in posterior fossa brain tumors: A preclinical study in a canine glioma model. J Neurosurg 1993; Oct; 79(4):562-568. |
11. Tang T, Segura A, Chen Y, Ricci L, Franciosi R, Splaingard M. Lubinsky M. Neonatal hypotonia and cardiomyopathy secondary to type IV glycogenosis. Acta Neuropathol 1994; 87:531-536. |
12. Rabinowitz L, Luchetti M, Segura A, Esterly N. Acrally Occurring Dermatofibrosarcoma Protuberans in Children and Adults. J Dermatol Surg Oncol 1994; 20:655-659. |
13. Whelan H, Kras L, Ozker K, Bajic D, Schmidt M, Lui Y, Trembath L, Uzum F, Meyer G, Segura A, Collier B. Selective incorporation of 111In-labeled PHOTOFRINTM by glioma tissue in vivo. J Neuro-Onc 1994; 20:7-13. |
14. Stokes K, Rabinowitz L, Segura A, Esterly N. Cutaneous Mucinosis of Infancy. Ped Derm 1994; 11:246-251. |
15. Zvulunow A, Sell L, Segura A, Esterly N. Firm Black Exophytic Tumor on the Foot of a Black Child. Ped Derm 1994; 11:358-361. |
16. Whelan H, Williams M, Bajic D, Segura A, McAuliffe T, Chitambar C. Prevention of Gallium Toxicity by Hyperhydration in Treatment of Medulloblastoma. Pediatr Neurol 1994; 10:217-220. |
17. Linder J, Harris G, Segura A. Periorbital Infantile Myofibromatosis. Archives of Ophthalmology 1996; 114:219-222. |
18. Flomenberg P, Piaskowski V, Harb J, Segura A, Casper J. Spontaneous, Persistent infection of a B-cell Lymphoma with Adenovirus. J Med Virol. 1996 Mar; 48(3):267-272. |
19. Baselga E, Drolet B, Segura A, Leonardi C, Esterly N. Dermatomal lichenoid chronic graft-vs-host disease following varicella zoster infection despite absence of viral genoma. J Cut Path 1996; 23(6):576-581. |
20. Margolis D, Casper J, Segura A, Janczak T, McOlash L, Fisher B., Miller K, Gorski J. Infiltrating T cells during liver graft-versus-host disease show a restricted T-cell repertoire. Biology of Blood and Marrow Transplantation, 2000; 6(4):408-415. |
21. Cham P, Drolet B, Segura A, Esterly N. Congenital Volkmann ischemic contractures: A case report and review. British Journal of Dermatology 2004; 150(2):357-363. |
22. Franciosi R, Segura A. Sudden and unexpected fetal death associated with agenesis of the arcuate nucleus in the medulla. American Journal of Perinatology 2004; 21(7):421-424. |
23. Rao A, Parakininkas D, Hintermeyer M, Segura A, Rice T. Bilateral lung transplant in Gauchers type 1disease. Pediatric Transplantation 2005; 9(2):239-243. |
24. Zangwill S, Brown M, Bryke C, Cava J, Segura A. Marfan Syndrome Type II: There is more to Marfan Syndrome than Fibrillin I. Congenital Heart Disease 2006; 1(5):229-232. |
25. Smart DR, Taintor AR, Kelly ME, Lyon VB, Segura A, Jensen JN, Drolet BA. Microcystic Adnexal Carcinoma: The First Reported Congenital Case. Pediatric Dermatology 2011; 1:35-38. |
26. Collins CL, Bartz P, Lal D, Segura A, Woods R, Tower RL. Significant response to oral etoposide in the treatment of an unresectable cardiac sarcoma. J Pediatr Hematol Oncol. 2014 May; 36(4):e237-40. doi: 10.1097/MPH.0b013e318290c3b8. PMID: 23652877 |
27. Gheorghe G, Rangarajan HG, Camitta B, Segura A, Kroft S, Southern JF. T-Cell/Histiocyte-Rich Large B-Cell Lymphoma in Pediatric Patients: An Under-Recognized Entity? Ann Clin Lab Sci. Winter; 45(1):73-8, 2015. PMID: 25696014 |
28. Humphrey SR, Juern AM, Chusid MJ, Segura AD, Chiu YE. New Pustular Lesions in an Infant with Fever. Pediatr Dermatol. 2015 Sep-Oct;32(5):737-8. |
29. Hong JC, Kim J, Browning M, Wagner A, Lerret S, Segura AD, Zimmerman MA. Modified Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy for Hepatoblastoma in a Small Infant: How Far Can We Push the Envelope? Ann Surg. 2017 08;266(2):e16-e17. |
30. Chiang JCH, Harreld JH, Orr BA, Sharma S, Ismail A, Segura AD, Ellison DW. Low-grade spinal glioneuronal tumors with BRAF gene fusion and 1p deletion but without leptomeningeal dissemination. Acta Neuropathol. 2017 07;134(1):159-162. PMCID: PMC5848506. |
31. Alexander Tassopoulos, MD, Melissa Wein, MD, Annette Segura, MD. Traumatic rupture of a giant congenital splenic cyst presenting as peritonitis. Radiology Case Reports, Volume 12(2):401-404, June 2017. PMID: PMC5417624 |
32. Nemeth K, Szabo S, Cottrell CE, McNulty SM, Segura A, Sokumbi O, Browning M, and Siegel DH. Mosaic pathogenic HRAS variants in a patient with nevus spilus with agminated Spitz nevi and parametrial-uterine rhabdomyosarcoma. Br J Dermatol 2018 March; 178(3):804-806. PMID: 29193020 |
33. Chiang J, Dalton J, Upadhyaya SA, Patay Z, Qaddoumi I, Li X, Segura AD, Sharma S, Ismail A, Shurtleff SA, Raimondi SC. Chromosome arm 1q gain is an adverse prognostic factor in localized and diffuse leptomeningeal glioneuronal tumors with BRAF gene fusion and 1p deletion. Acta Neuropathol. 2018 Nov 21. |
Abstracts |
1. Whelan H, Segura A, Traul D, Przybylski C, Sieber F. Interactions of Merocyanine-540 with Human Brain Tumor cells: Preferential Binding In Vivo and Dye-sensitized Photoinactivation In Vitro. Annals of Neurology 1991; 30:459-460. |
2. Whelan H, Schmidt M, Segura A, Strother D, Kubacki D, Meyer G. The role of photodynamic therapy in posterior fossa brain tumors: A preclinical study in a canine glioma model. Annals of Neurology 1992; 32(3):471. |
3. Whelan H, Ozker K, Bajic D, Schmidt M, Liu Y, Trembath L, Uzum F, Meyer G, Segura A, Collier B. Selective Uptake of 111In-Photofrin in Posterior Fossa Brain Tumors. Annals of Neurology 1993; 34(3):469. |
4. Whelan H, Strother D, Ozker K, Kras L, Schmidt M, Liu Y, Trembath L, Uzum F, Meyer G, Segura A, Collier D, Kovnar E. Selective incorporation of 111In-labeled Photofrin by glioma tissue in vivo. Pediatr Neurosurg 1994; 21:160-161. |
5. Whelan H, Strother D, Kovnar E, Williams M, Bajic D, Flores R, Schmidt M, Segura A, McAuliffe T, Chitambar C. Gallium nitrate for microscopic disease in medulloblastoma: Preclinical study in a murine model. Pediatr Neurosurg 1994; 21:161. |
6. Gheorghe G, Rangarajan H Reiswig A Camitta B, Segura A, Kroft S, Southern J. Pediatric T cell rich large B cell lymphoma: an underrecognized entity? Pediatric and Developmental Pathology 13, 498-512, 2010. |
7. Fahmy MD, Gupta A, Padilla RJ, Segura A, Brookes CD. Desmoplastic fibroma associated with tuberous sclerosis: case report and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Mar 16. pii: S2212-4403(19)30398-0. doi: 10.1016/j.oooo.2019.03.008. [Epub ahead of print] Review. PMID: 31078508 |