CURRICULUM VITAE
Ariel Nelson MD
Ariel Nelson MD
Assistant Professor
Department of Medicine
Division of Hematology and Oncology - Medicine
Department of Medicine
Division of Hematology and Oncology - Medicine
OFFICE ADDRESS: |
Froedtert Hospital |
9200 W Wisconsin Ave |
Milwaukee, WI 53226 |
EDUCATION: |
09/2004 - 05/2008 BA, Vassar College, Poughkeepsie, NY |
09/2009 - 05/2013 MD, State University of New York at Buffalo, Buffalo, NY |
08/2019 - 12/2021 MS Clinical and Translational Research, Medical College of Wisconsin, Milwaukee, WI |
CENTER/INSTITUTE AFFILIATIONS: |
04/17/2024 - Present Member, Cancer Center, Medical College of Wisconsin, Milwaukee, WI, US |
ADMINISTRATIVE APPOINTMENTS: |
08/01/2022 - Present Genitourinary Disease Operating Team Vice Chair, Medicine, Hematology/Oncology, The Medical College of Wisconsin, Milwaukee, WI |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
06/2020 - Present Internal Medicine Resident Oncology Education Coordinator, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, WI 53226 |
07/01/2022 - Present Hem/Onc Fellowship Core Clinical Faculty, Medicine, Hem/Onc, MCW |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Journal Review |
04/01/2024 - 05/01/2024 Frontiers in Oncology, Section Genitourinary Oncology |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Regional |
Ariel Nelson, MD, MS, Recent Advances in Molecular Guided Treatment of GU Malignancies, Central Illinois Hematology Oncology Conference, Peoria, Illinois, 04/25/2025 |
Local |
Ariel Nelson, Advances in Management of Urothelial Carcinoma, The Medical College of Wisconsin, Department of Pathology Grand Rounds, Milwaukee, WI, 08/12/2022 |
Ariel Nelson, MD, Recent Advances in the Management of Urothelial Carcinoma, Department of Medicine Grand Rounds, Milwaukee, WI, 02/23/2024 |
Ariel Nelson, MD, Recent Advances in Management of Urothelial Carcinoma, Department of Urology Grand Rounds, Milwaukee, WI, 08/28/2024 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
08/2022 - Present Member, Intern Selection Committee, Medicine, Medical College of Wisconsin |
01/2025 - Present Member, Faculty Development Committee, Medicine, The Medical College of Wisconsin |
MCW TEACHING ACTIVITIES: |
Graduate Student Education |
11/22/2022 - Present Yearly Genomics and Immunotherapy Lecture for Graduate Students |
Resident and Fellow Education |
Yearly Bladder Cancer Core Lecture for HemOnc Fellows |
Community/Lay Public |
05/22/2024 Bladder Cancer Basics: An Informational Lecture to overview diagnosis and management of bladder cancer for patients and caregivers in the bladder cancer support group |
EXTRAMURAL TEACHING: |
Medical Student Education |
08/2021 - Present The Medical College of Wisconsin, Delivering Difficult News Small Group Facilitator |
Resident and Fellow Education |
02/12/2025 - Present The Medical College of Wisconsin, Immunotherapy for Cancer Care Lecture for Internal Medicine Residents |
ADVISORY BOARD MEMBERSHIP: |
05/14/2024 Invited member of the Adaptimmune pharmaceutical virtual advisory board for urothelial carcinoma. |
10/22/2024 Invited Member of the Merck & Co. Pharmaceutical US Kidney and Bladder Advisory Board Meeting |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Nelson AA, Cronk RJ, Lemke EA, Szabo A, Khaki AR, Diamantopoulos LN, Grivas P, Nezami BG, MacLennan GT, Zhang T, Hoimes CJ. Early Bone Metastases are Associated with Worse Outcomes in Metastatic Urothelial Carcinoma Bladder Cancer. 2021;7(1):33-42. |
2. Smith NJ, Mukherjee D, Wang Y, Brazauskas R, Nelson AA, Cortina CS. Epidemiology and outcomes of primary pediatric lung malignancies: Updates from the SEER database. Am J Surg. 2021 Oct;222(4):861-866. PMCID: PMC8985451 |
3. Esagian SM, Khaki AR, Diamantopoulos LN, Carril-Ajuria L, Castellano D, De Kouchkovsky I, Park JJ, Alva A, Bilen MA, Stewart TF, McKay RR, Santos VS, Agarwal N, Jain J, Zakharia Y, Morales-Barrera R, Devitt ME, Nelson A, Hoimes CJ, Shreck E, Gartrell BA, Sankin A, Tripathi A, Zakopoulou R, Bamias A, Rodriguez-Vida A, Drakaki A, Liu S, Kumar V, Lythgoe MP, Pinato DJ, Murgic J, Fröbe A, Joshi M, Isaacsson Velho P, Hahn N, Alonso Buznego L, Duran I, Moses M, Barata P, Galsky MD, Sonpavde G, Yu EY, Msaouel P, Koshkin VS, Grivas P. Immune checkpoint inhibitors in advanced upper and lower tract urothelial carcinoma: a comparison of outcomes. BJU Int. 2021 Aug;128(2):196-205. |
4. Khaki AR, Li A, Diamantopoulos LN, Miller NJ, Carril-Ajuria L, Castellano D, De Kouchkovsky I, Koshkin V, Park J, Alva A, Bilen MA, Stewart T, Santos V, Agarwal N, Jain J, Zakharia Y, Morales-Barrera R, Devitt M, Nelson A, Hoimes CJ, Shreck E, Gartrell BA, Sankin A, Tripathi A, Zakopoulou R, Bamias A, Rodriguez-Vida A, Drakaki A, Liu S, Kumar V, Lythgoe MP, Pinato DJ, Murgic J, Fröbe A, Joshi M, Isaacsson Velho P, Hahn N, Alonso Buznego L, Duran I, Moses M, Barata P, Galsky MD, Sonpavde G, Yu EY, Shankaran V, Lyman GH, Grivas P. A New Prognostic Model in Patients with Advanced Urothelial Carcinoma Treated with First-line Immune Checkpoint Inhibitors. Eur Urol Oncol. 2021 Jun;4(3):464-472. PMCID: PMC8169524 |
5. Beckermann KE, Shah NJ, Campbell MT, Haas NB, Nelson A, Ornstein MC, Mao S, Keshava-Prasad HS, Hammers H, Gao X, Gourdin T, George S, Hoimes CJ, Hussain A, Jonasch E, Rini BI, Voss MH. Phase 1b/2 study of batiraxcept alone and in combination with cabozantinib with or without nivolumab for advanced clear cell renal cell carcinoma. Oncologist. 2025 Jun 04;30(6). PMCID: PMC12205982 |
6. Wellen A, Pierro MJ, Wanat KA, Nelson AA. Case Report: Oral lichenoid mucositis in a patient with metastatic renal cell carcinoma undergoing treatment with pembrolizumab and axitinib. Front Oncol. 2025;15:1495446. PMCID: PMC12127167 |
7. Miller NJ, Khaki AR, Diamantopoulos LN, Bilen MA, Santos V, Agarwal N, Morales-Barrera R, Devitt M, Nelson A, Hoimes CJ, Shreck E, Assi H, Gartrell BA, Sankin A, Rodriguez-Vida A, Lythgoe M, Pinato DJ, Drakaki A, Joshi M, Isaacsson Velho P, Hahn N, Liu S, Alonso Buznego L, Duran I, Moses M, Jain J, Murgic J, Barata P, Tripathi A, Zakharia Y, Galsky MD, Sonpavde G, Yu EY, Lyman GH, Grivas P. Histological Subtypes and Response to PD-1/PD-L1 Blockade in Advanced Urothelial Cancer: A Retrospective Study. J Urol. 2020 Jul;204(1):63-70. PMCID: PMC7289665 |
8. Ansari-Gilani K, Tirumani SH, Smith DA, Nelson A, Alahmadi A, Hoimes CJ, Ramaiya NH. Myocarditis associated with immune checkpoint inhibitor therapy: a case report of three patients. Emerg Radiol. 2020 Aug;27(4):455-460. |
9. Khaki AR, Li A, Diamantopoulos LN, Bilen MA, Santos V, Esther J, Morales-Barrera R, Devitt M, Nelson A, Hoimes CJ, Shreck E, Assi H, Gartrell BA, Sankin A, Rodriguez-Vida A, Lythgoe M, Pinato DJ, Drakaki A, Joshi M, Isaacsson Velho P, Hahn N, Liu S, Alonso Buznego L, Duran I, Moses M, Jain J, Murgic J, Baratam P, Barata P, Tripathi A, Zakharia Y, Galsky MD, Sonpavde G, Yu EY, Shankaran V, Lyman GH, Grivas P. Impact of performance status on treatment outcomes: A real-world study of advanced urothelial cancer treated with immune checkpoint inhibitors. Cancer. 2020 Mar 15;126(6):1208-1216. PMCID: PMC7050422 |
10. Dhakal B, Nelson A, Guru Murthy GS, Fraser R, Eastwood D, Hamadani M, Pasquini M, D'Souza A, Hari P. Autologous Hematopoietic Cell Transplantation in Patients With Multiple Myeloma: Effect of Age. Clin Lymphoma Myeloma Leuk. 2017 Mar;17(3):165-172. |
11. Nelson AA, Harrington AM, Kroft S, Dahar MA, Hamadani M, Dhakal B. Presentation and management of post-allogeneic transplantation EBV-positive mucocutaneous ulcer. Bone Marrow Transplant. 2016 Feb;51(2):300-2. |
12. Makrakis D, Talukder R, Diamantopoulos LN, Carril-Ajuria L, Castellano D, De Kouchkovsky I, Koshkin VS, Park JJ, Alva A, Bilen MA, Stewart TF, McKay RR, Santos VS, Agarwal N, Jain J, Zakharia Y, Morales-Barrera R, Devitt ME, Grant M, Lythgoe MP, Pinato DJ, Nelson A, Hoimes CJ, Shreck E, Gartrell BA, Sankin A, Tripathi A, Zakopoulou R, Bamias A, Murgic J, Fröbe A, Rodriguez-Vida A, Drakaki A, Liu S, Kumar V, Di Lorenzo G, Joshi M, Isaacsson-Velho P, Buznego LA, Duran I, Moses M, Barata P, Sonpavde G, Yu EY, Wright JL, Grivas P, Khaki AR. Association of prior local therapy and outcomes with programmed-death ligand-1 inhibitors in advanced urothelial cancer. BJU Int. 2022 Nov;130(5):592-603. PMCID: PMC10257152 |
13. Hall WA, Bedi M, Kilari D, Bylow KA, Burfeind J, Johnstone C, Siker M, Currey A, See WA, Nelson A, Johnson S, Straza M, Lawton CAF. Long-Term Outcomes of Dose-Escalated Pelvic Lymph Node Intensity-Modulated Radiation Therapy (IMRT) With a Simultaneous Hypofractionated Boost to the Prostate for Very High-Risk Adenocarcinoma of the Prostate: A Prospective Phase II Clinical Trial. Pract Radiat Oncol. 2021;11(6):527-533. PMCID: PMC8638529 |
14. Dubey S, Singh M, Nelson A, Karan D. A Perspective on <i>Withania somnifera</i> Modulating Antitumor Immunity in Targeting Prostate Cancer. J Immunol Res. 2021;2021:9483433. PMCID: PMC8413038 |
15. Talukder R, Makrakis D, Diamantopoulos LN, Carril-Ajuria L, Castellano D, De Kouchkovsky I, Koshkin VS, Park JJ, Alva A, Bilen MA, Stewart TF, McKay RR, Santos VS, Agarwal N, Jain J, Zakharia Y, Morales-Barrera R, Devitt ME, Grant M, Lythgoe MP, Pinato DJ, Nelson A, Hoimes CJ, Shreck E, Gartrell BA, Sankin A, Tripathi A, Zakopoulou R, Bamias A, Murgic J, Fröbe A, Rodriguez-Vida A, Drakaki A, Liu S, Kumar V, Lorenzo GD, Joshi M, Velho PI, Buznego LA, Duran I, Moses M, Barata P, Sonpavde G, Yu EY, Wright JL, Grivas P, Khaki AR. Response and Outcomes to Immune Checkpoint Inhibitors in Advanced Urothelial Cancer Based on Prior Intravesical Bacillus Calmette-Guerin Clinical Genitourinary Cancer. 2022. |
16. Makrakis D, Talukder R, Lin GI, Diamantopoulos LN, Dawsey S, Gupta S, Carril-Ajuria L, Castellano D, de Kouchkovsky I, Koshkin VS, Park JJ, Alva A, Bilen MA, Stewart TF, McKay RR, Tripathi N, Agarwal N, Vather-Wu N, Zakharia Y, Morales-Barrera R, Devitt ME, Cortellini A, Fulgenzi CAM, Pinato DJ, Nelson A, Hoimes CJ, Gupta K, Gartrell BA, Sankin A, Tripathi A, Zakopoulou R, Bamias A, Murgic J, Fröbe A, Rodriguez-Vida A, Drakaki A, Liu S, Lu E, Kumar V, Lorenzo GD, Joshi M, Isaacsson-Velho P, Buznego LA, Duran I, Moses M, Jang A, Barata P, Sonpavde G, Yu EY, Montgomery RB, Grivas P, Khaki AR. Association Between Sites of Metastasis and Outcomes With Immune Checkpoint Inhibitors in Advanced Urothelial Carcinoma. Clin Genitourin Cancer. 2022 Oct;20(5):e440-e452. PMCID: PMC10257151 |
17. Talukder R, Makrakis D, Lin GI, Diamantopoulos LN, Dawsey S, Gupta S, Carril-Ajuria L, Castellano D, de Kouchkovsky I, Jindal T, Koshkin VS, Park JJ, Alva A, Bilen MA, Stewart TF, McKay RR, Tripathi N, Agarwal N, Vather-Wu N, Zakharia Y, Morales-Barrera R, Devitt ME, Cortellini A, Fulgenzi CAM, Pinato DJ, Nelson A, Hoimes CJ, Gupta K, Gartrell BA, Sankin A, Tripathi A, Zakopoulou R, Bamias A, Murgic J, Fröbe A, Rodriguez-Vida A, Drakaki A, Liu S, Lu E, Kumar V, Lorenzo GD, Joshi M, Isaacsson-Velho P, Buznego LA, Duran I, Moses M, Barata P, Sonpavde G, Wright JL, Yu EY, Montgomery RB, Hsieh AC, Grivas P, Khaki AR. Association of the Time to Immune Checkpoint Inhibitor (ICI) Initiation and Outcomes With Second Line ICI in Patients With Advanced Urothelial Carcinoma. Clin Genitourin Cancer. 2022 Dec;20(6):558-567. PMCID: PMC10233855 |
18. Kim AE, Nelson A, Stimpert K, Flyckt RL, Thirumavalavan N, Baker KC, Weinmann SC, Hoimes CJ. Minding the Bathwater: Fertility and Reproductive Toxicity in the Age of Immuno-Oncology. JCO Oncol Pract. 2022 Dec;18(12):815-822. PMCID: PMC10166412 |
Books, Chapters, and Reviews |
1. Thapa B, Nelson A, Kilari D. Novel targets in development for advanced renal cell carcinoma Integrating Multidisciplinary Treatment for Advanced Renal Cell Carcinoma. 1 November 2023:309-342. |
2. Nelson AA, Cronk RJ, Lemke EA, Szabo A, Khaki AR, Diamantopoulos LN, Grivas P, Nezami BG, MacLennan GT, Zhang T, Hoimes CJ. Early Bone Metastases are Associated with Worse Outcomes in Metastatic Urothelial Carcinoma. Bladder Cancer. 2021;7(1):33-42. PMCID: PMC11181800 |
Abstracts |
1. Nelson, A., et al. Patterns of metastases, treatment (tx), and outcomes in bone predominant (BP) metastatic urothelial carcinoma (mUC). J Clin Oncol 36, 2018 (suppl; abstr e16523) |
2. Nelson,. A, et al. Phase II study of eribulin mesylate for treatment of CNS metastases (mets) in metastatic breast cancer (mBC). J Clin Oncol 37, 2019 (suppl; abstr e12571) |
3. Nelson, A., et al. Association of early bone metastases and outcomes of the bone predominant metastatic urothelial carcinoma (BP mUC) phenotype. J Clin Oncol 37, 2019 (suppl; abstr e16016) |
4. Alahmadi, A., Nelson, A., et al Association between age, risk of severe (Grade 3-4) immune-related adverse events (sirAE), and mortality in patients receiving immune checkpoint inhibitors (ICI). J Clin Oncol 37, 2019 (suppl; abstr 6597) |
5. Ardeshir- Larijani F,. Nelson, A., et al. Outcomes of melanoma patients with brain metastases receiving immune checkpoint inhibitor (ICI) therapy. J Clin Oncol 37, 2019 (suppl; abstr e21028) |
6. Smith, D,. Laukamp, K., Campbell, M., Devita, R., Nelson, A., et al. Incidence and characteristics of emergency department presentations during immune checkpoint inhibitor therapy. J Clin Oncol 37, 2019 (suppl; abstr e14164) |
7. Khaki, A., Diamantopolous, L., Devitt, M., Drakaki, A., Joshi, M., Velho, P., Nelson, A., et al. Outcomes of patients (pts) with metastatic urothelial cancer (mUC) and poor performance status (PS) receiving anti-PD(L)1 agents. J Clin Oncol 37, 2019 (suppl; abstr 4525) |
8. Laukamp, K., Liput, J., Smith, D., Nelson, A., et al. Major lab abnormalities as biomarkers in patients treated with immune checkpoint inhibitors: A single institution study of 1044 patients. J Clin Oncol 37, 2019 (suppl; abstr e14108) |
9. Ariel Ann Nelson, Mariel Molina Nunez, Kathryn A. Bylow, Aniko Szabo, Kenneth Iczkowski,
Deepak Kilari. Immunohistochemical (IHC) subtypes of metastatic bladder cancer (mBC) using GATA3 and CK5/6. Journal of Clinical Oncology . Journal of Clinical Oncology 41, no. 6_suppl (February 20, 2023) 557-557.. |
10. Katy Beckermann, Matthew T Campbell, Naomi B. Haas, Moshe Chaim Ornstein, Xin Gao, Shifeng S. Mao, Hans J. Hammers, Saby George, Ariel Ann Nelson, Theodore Stewart Gourdin, Holavanahalli Keshava-Prasad, Arif Hussain, Christopher J. Hoimes, Hongxia Yan, Vanessa Esquibel, Gail McIntyre, Robert B. Geller, Martin H Voss, Brian I. Rini, Neil J. Shah. Phase 2 study of batiraxcept (AVB-S6-500, an AXL inhibitor) as monotherapy, in combination with cabozantinib (cabo), and in combination with cabo and nivolumab (nivo) in patients with advanced clear cell renal cell carcinoma (ccRCC). Journal of Clinical Oncology . J Clin Oncol 41, 2023 (suppl 16; abstr 4534). |
11. Ariel Ann Nelson, Aniko Szabo, Deepak Kilari. Impact of cytoreductive nephrectomy (CRN) on overall survival (OS) in metastatic non–clear cell renal cancer (nccRCC). Journal of Clinical Oncology . J Clin Oncol 41, 2023 (suppl 6; abstr 730). |
12. Mirsky MM, Mitchell C, Hong A, Cao S, Fu P, Margevicius S, Wu S, Dowlati A, Nelson A, Eva Selfridge J, Ramaiya N, Hoimes C, Alahmadi A, Bruno DS. Outcomes of Antineoplastic Immunotherapy at a Large Healthcare Organization: Impact of Provider, Race and Socioeconomic Status Cancer Management and Research. 2023;15:913-927. |
13. Talukder R, Makrakis D, Diamantopoulos LN, Carril-Ajuria L, Castellano D, De Kouchkovsky I, Koshkin VS, Park JJ, Alva A, Bilen MA, Stewart TF, McKay RR, Santos VS, Agarwal N, Jain J, Zakharia Y, Morales-Barrera R, Devitt ME, Grant M, Lythgoe MP, Pinato DJ, Nelson A, Hoimes CJ, Shreck E, Gartrell BA, Sankin A, Tripathi A, Zakopoulou R, Bamias A, Murgic J, Fröbe A, Rodriguez-Vida A, Drakaki A, Liu S, Kumar V, Lorenzo GD, Joshi M, Velho PI, Buznego LA, Duran I, Moses M, Barata P, Sonpavde G, Yu EY, Wright JL, Grivas P, Khaki AR. Response and Outcomes to Immune Checkpoint Inhibitors in Advanced Urothelial Cancer Based on Prior Intravesical Bacillus Calmette-Guerin. Clin Genitourin Cancer. 2022 Apr;20(2):165-175. PMCID: PMC8995351 |
14. Katy Beckermann, Matthew T Campbell, Naomi B. Haas, Moshe Chaim Ornstein, Xin Gao, Shifeng S. Mao, Hans J. Hammers, Saby George, Ariel Ann Nelson, Theodore Stewart Gourdin, Holavanahalli Keshava-Prasad, Arif Hussain, Christopher J. Hoimes, Hongxia Yan, Vanessa Esquibel, Gail McIntyre, Robert B. Geller, Martin H Voss, Brian I. Rini, Neil J. Shah. Phase 2 study of batiraxcept (AVB-S6-500, an AXL inhibitor) as monotherapy, in combination with cabozantinib (cabo), and in combination with cabo and nivolumab (nivo) in patients with advanced clear cell renal cell carcinoma (ccRCC) J Clin Oncol . J Clin Oncol 41, 2023 (suppl 16; abstr 4534). |
15. Ariel Ann Nelson, Kristin Riemersma, Kathryn A. Bylow, Michael Holt, Deepak Kilari. Impact of pre-treatment hemoglobin (Hgb) on outcomes in metastatic castration resistant prostate cancer (mCRPC) with lutetium-177-PSMA-617 (Lu-177 J Clin Oncol . J Clin Oncol 41, 2023 (suppl 16; abstr e17065). |
16. Mirsky MM, Mitchell C, Hong A, Cao S, Fu P, Margevicius S, Wu S, Dowlati A, Nelson A, Selfridge JE, Ramaiya N, Hoimes C, Alahmadi A, Bruno DS. Outcomes of Antineoplastic Immunotherapy at a Large Healthcare Organization: Impact of Provider, Race and Socioeconomic Status. Cancer Manag Res. 2023;15:913-927. PMCID: PMC10478776 |
17. Ariel Ann Nelson, Christina Ladwig, Kristin Riemersma, Kathryn A. Bylow, Deepak Kilari. Disparities in medical oncology visit adherence among African American (AA) men with prostate cancer (pCa) J Clin Oncol . J Clin Oncol 41, 2023 (suppl 16; abstr e18671). |
18. Vineel Bhatlapenumarthi, Navonil De Sarkar, Anannya Patwari, Emmanuel S. Antonarakis, Ariel Ann Nelson, Deepak Kilari. Homologous recombination repair (HRR) alterations may be passenger events in patients with advanced prostate cancer (PC) with high tumor mutational burden (hTMB) J Clin Oncol. J Clin Oncol 42, 2024 (suppl 4; abstr 206). |
19. David H Aggen, Alejandro Garcia, Jose M Saro Suarez, Amy Sauer, Sebastiano Cristiani, Francine Elizabeth Brophy, Sharon Streets, Elliot Norry, Ariel Ann Nelson, Deepak Kilari, Benjamin Garmezy, John A. Charlson, Jon Zugazagoitia, Emiliano Calvo, Irene Moreno, Victor Moreno, Christopher J. Hoimes, David S. Hong, Andres Cervantes. New phase 1 SURPASS trial cohort: Early-line ADP-A2M4CD8 T-cell receptor T-cell therapy plus pembrolizumab in urothelial carcinoma J Clin Oncol. J Clin Oncol 42, 2024 (suppl 4; abstr TPS708). |
20. Michael Pierro, Ariel Ann Nelson, John Xie, Albert Jang, Kathryn A. Bylow, Pedro C. Barata, Colleen Anne Lawton, Deepak Kilari. Impact of pre-existing anemia and/or packed red blood cell transfusion prior to Radium-223 administration on oncologic outcomes. J Clin Oncol . J Clin Oncol 41, 2023 (suppl 6; abstr 67). |
