Medical College of Wisconsin
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CURRICULUM VITAE

Bo Wang PhD
Assistant Professor
Department of Biomedical Engineering

OFFICE ADDRESS:
8701 Watertown Plank Road
Milwaukee, WI 53226

EDUCATION:
01/10/2008 - 05/10/2012 Ph.D, Mississippi State University, MS

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
02/20/2012 - 12/31/2015 Postdoc Fellow, Northwestern University, Chicago, IL

FACULTY APPOINTMENTS:
01/10/2016 - 12/31/2018 Assistant Professor, Alabama state university, 915 S. Jackson Street, Montgomery, AL 36104
2019 - Present Assistant Professor, Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI 53226

AWARDS AND HONORS:
2008 - 2012 Graduate Research Assistantships, Mississippi State University
2011 - Present Pediatric Workshop Scholarship, Tissue Engineering and Regenerative Medicine International Society
2014 - Present Annual Conference Travel Award, Tissue Engineering and Regenerative Medicine International Society
2015 - Present Postdoctoral Professional Development Travel Award, Northwestern University

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2008 - Present Biomedical Engineering Society (Member)
2011 - Present Tissue Engineering and Regenerative Medicine Society (Member)
2012 - Present American Heart Association (Member)
2017 - Present Member, Society for Biomaterials (Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
Biochemical Engineering Journal
Theranostics Journal
ACS Applied Biomaterials
Biomed Research International
Journal of Stem Cells and Regenerative Medicine
Drug Delivery and Translational Research
Journal of Biophotonics
Communication Biology

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Tissue-Engineered Vascular Graft of Small Diameter Using Porcine Artery
Source:
Advancing a Healthier Wisconsin
Role & Effort:
Principal Investigator
Dates:
2019 - 2022
Direct Funds:
$590,528
  
Title:
Develop an Individualized Composite as an Interface for Severe Cleft Palate Repair
Source:
Research Affairs Committee
Role & Effort:
Principal Investigator
Dates:
2021
Direct Funds:
$25,000
  
Prior
Peer Review
Title:
Acq uis ition of a Multimaterial 3 3-D B iopl otter for Interdiscipl inary Research and EducationEducation
Source:
National Science Foundation
Role & Effort:
Co-Principal Investigator
PI:
Derrick Dean
Dates:
2016 - 2017
Direct Funds:
$271,535
  
Title:
Optimization and Enhancement of Hepatic Differentiation for Mesenchymal Stem Cells via Biofunctional Modification Modification
Source:
National Science Foundation
Role & Effort:
Principal Investigator
Dates:
2017 - 2021
Direct Funds:
$300,000
  
Title:
: “Dev elo pment of an Individualized Multiplex Composite as an Interface for Severe Cleft Pa late Repair” Repair
Source:
National Institute of Health
Role & Effort:
Principal Investigator
Dates:
2018 - 2019
Direct Funds:
$354,805
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
International
The XIth International Workshop on EPR (ESR) in Biology and Medicine, Krakow, Poland, 2019
 
National
University of Georgia, School of Chemical, Materials, and Biomedical Engineering Graduate Seminar Series, Athens, Georgia, 2018
 
Local
Marquette University & Medical College of Wisconsin Biomedical Engineering Graduate Seminar Series, Milwaukee, Wisconsin, 2018
 

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
Graduate Students
MS Students Advised
Brian Delaney, Marquette University - Medical College of Wisconsin
PhD Students Advised
Carolyn Czerniak, Marquette University - Medical College of Wisconsin
Austin Stellpflug, Marquette University - Medical College of Wisconsin
Xiaolong Wang, Marquette University - Medical College of Wisconsin
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Li W, Wang F, Barnett C, Wang B. A comparative study on fabrication techniques of gelable bone matrix derived from porcine tibia. J Biomed Mater Res B Appl Biomater. 2021 Dec;109(12):2131-2141.
2. Wang B, Johnson A, Li W. Development of an extracellular matrix-enriched gelatin sponge for liver wound dressing. J Biomed Mater Res A. 2020 Oct;108(10):2057-2068.
3. Wang B, Li W, Harrison J. An Evaluation of Wound Healing Efficacy of a Film Dressing Made from Polymer-integrated Amnion Membrane. Organogenesis. 2020 Oct 01;16(4):126-136. PMCID: PMC7714469
4. Li W, Fu Y, Jiang B, Lo AY, Ameer GA, Barnett C, Wang B. Polymer-integrated amnion scaffold significantly improves cleft palate repair. Acta Biomater. 2019 Jul 01;92:104-114.
5. Copeland KM, Wang B, Shi X, Simionescu DT, Hong Y, Bajona P, Sacks MS, Liao J. Decellularization in heart valve tissue engineering Advances in Heart Valve Biomechanics: Valvular Physiology, Mechanobiology, and Bioengineering. 8 April 2019:289-317.
6. Wang B, Li W. Development of an extracellular matrix-enriched gelatin sponge for liver wound dressing Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium. 2019;40:124.
7. Wang B, Li W, Dean D, Mishra MK, Wekesa KS. Enhanced hepatogenic differentiation of bone marrow derived mesenchymal stem cells on liver ECM hydrogel. J Biomed Mater Res A. 2018 Mar;106(3):829-838.
8. Wang B, Jakus AE, Baptista PM, Soker S, Soto-Gutierrez A, Abecassis MM, Shah RN, Wertheim JA. Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix-A Comparative Analysis of Bioartificial Liver Microenvironments. Stem Cells Transl Med. 2016 Sep;5(9):1257-67. PMCID: PMC4996436
9. Wang B, Wertheim JA. Experimental Cell Therapy for Liver Dysfunction Translating Regenerative Medicine to the Clinic. 2016:309-313.
10. Uzarski JS, Bijonowski BM, Wang B, Ward HH, Wandinger-Ness A, Miller WM, Wertheim JA. Dual-Purpose Bioreactors to Monitor Noninvasive Physical and Biochemical Markers of Kidney and Liver Scaffold Recellularization. Tissue Eng Part C Methods. 2015 Oct;21(10):1032-43. PMCID: PMC4593971
11. Li W, Ma G, Brazile B, Li N, Dai W, Butler JR, Claude AA, Wertheim JA, Liao J, Wang B. Investigating the Potential of Amnion-Based Scaffolds as a Barrier Membrane for Guided Bone Regeneration. Langmuir. 2015 Aug 11;31(31):8642-53.
12. Wang B, Patnaik SS, Brazile B, Butler JR, Claude A, Zhang G, Guan J, Hong Y, Liao J. Establishing Early Functional Perfusion and Structure in Tissue Engineered Cardiac Constructs. Crit Rev Biomed Eng. 2015;43(5-6):455-71. PMCID: PMC5166426
13. Brazile B, Wang B, Wang G, Bertucci R, Prabhu R, Patnaik SS, Butler JR, Claude A, Brinkman-Ferguson E, Williams LN, Liao J. On the bending properties of porcine mitral, tricuspid, aortic, and pulmonary valve leaflets. J Long Term Eff Med Implants. 2015;25(1-2):41-53. PMCID: PMC6721960
14. Hodge A, Lourensz D, Vaghjiani V, Nguyen H, Tchongue J, Wang B, Murthi P, Sievert W, Manuelpillai U. Soluble factors derived from human amniotic epithelial cells suppress collagen production in human hepatic stellate cells. Cytotherapy. 2014 Aug;16(8):1132-44.
15. Li W, Tamamura R, Wang B, Liu Q, Liu H, Liu T, Katase N, Xiao J, Nagatsuka H. Expressions of ABCG2, CD133, and podoplanin in salivary adenoid cystic carcinoma. Biomed Res Int. 2014;2014:132349. PMCID: PMC3998002
16. Wang B, Williams LN, de Jongh Curry AL, Liao J. Preparation of acellular myocardial scaffolds with well-preserved cardiomyocyte lacunae, and method for applying mechanical and electrical simulation to tissue construct. Methods Mol Biol. 2014;1181:189-202.
17. Wang B, Bertucci R, Li Z, Prabhu R, Williams L, Guan J, Liao J. Effect of thermosensitive hydrogel injection on mechanical behavior of porcine myocardium ASME 2013 Summer Bioengineering Conference, SBC 2013. 2013;1 A.
18. Wang B, Wang G, To F, Butler JR, Claude A, McLaughlin RM, Williams LN, de Jongh Curry AL, Liao J. Myocardial scaffold-based cardiac tissue engineering: application of coordinated mechanical and electrical stimulations. Langmuir. 2013 Sep 03;29(35):11109-17. PMCID: PMC3838927
19. Chow JP, Simionescu DT, Warner H, Wang B, Patnaik SS, Liao J, Simionescu A. Mitigation of diabetes-related complications in implanted collagen and elastin scaffolds using matrix-binding polyphenol. Biomaterials. 2013 Jan;34(3):685-95. PMCID: PMC3496025
20. Patnaik SS, Weed B, Borazjani A, Bertucci R, Begonia M, Wang B, Williams L, Liao J. Biomechanical characterization of sheep vaginal wall tissue: A potential application in human pelvic floor disorders ASME 2012 Summer Bioengineering Conference, SBC 2012. 2012:1193-1194.
21. Wang B, Tedder ME, Perez CE, Wang G, de Jongh Curry AL, To F, Elder SH, Williams LN, Simionescu DT, Liao J. Structural and biomechanical characterizations of porcine myocardial extracellular matrix. J Mater Sci Mater Med. 2012 Aug;23(8):1835-47. PMCID: PMC3523096
22. Simionescu DT, Chen J, Jaeggli M, Wang B, Liao J. Form Follows Function: Advances in Trilayered Structure Replication for Aortic Heart Valve Tissue Engineering. J Healthc Eng. 2012 Jun;3(2):179-202. PMCID: PMC3552623
23. Wang B, McCallum D, Williams L, Liao J. Evaluation of acellular mitral valve scaffolds: Anterior leaflet, posterior leaflet, and chordae tendineae ASME 2011 Summer Bioengineering Conference, SBC 2011. 2011(PARTS A AND B):239-240.
24. Wang B, Borazjani A, Tahai M, Curry AL, Simionescu DT, Guan J, To F, Elder SH, Liao J. Fabrication of cardiac patch with decellularized porcine myocardial scaffold and bone marrow mononuclear cells. J Biomed Mater Res A. 2010 Sep 15;94(4):1100-10. PMCID: PMC2933781
25. Williams C, Liao J, Joyce EM, Wang B, Leach JB, Sacks MS, Wong JY. Altered structural and mechanical properties in decellularized rabbit carotid arteries. Acta Biomater. 2009 May;5(4):993-1005. PMCID: PMC2680318
26. Liao J, Priddy LB, Wang B, Chen J, Vesely I. Ultrastructure of porcine mitral valve chordae tendineae. J Heart Valve Dis. 2009 May;18(3):292-9.
27. Wang R, Liu B, Wang B, Cong W, Xiao J. [Spatial and temporal changes of palatal cell proliferation and cell apoptosis of retinoic acid induced mouse cleft palate in different embryonic stages]. Hua Xi Kou Qiang Yi Xue Za Zhi. 2008 Oct;26(5):546-9.
28. Wang B, Shah M, Williams LN, de Jongh Curry AL, Hong Y, Zhang G, Liao J. Acellular Myocardial Scaffolds and Slices Fabrication, and Method for Applying Mechanical and Electrical Simulation to Tissue Construct. Methods Mol Biol. 2022;2485:55-70. PMCID: PMC9811994
29. Wang B, Sierad LN, Mercuri JJ, Simionescu A, Simionescu DT, Williams LN, Vela R, Bajona P, Peltz M, Ramaswamy S, Hong Y, Liao J. Structural and biomechanical characterizations of acellular porcine mitral valve scaffolds: anterior leaflets, posterior leaflets, and chordae tendineae Engineered Regeneration. December 2022;3(4):374-386.
30. Stellpflug A, Walls J, Hansen C, Joshi A, Wang B. From bone to nanoparticles: development of a novel generation of bone derived nanoparticles for image guided orthopedic regeneration. Biomater Sci. 2024 Jul 09;12(14):3633-3648. PMCID: PMC11238765
31. Stellpflug A, Caron J, Fasciano S, Wang B, Wang S. Bone-derived nanoparticles (BNPs) enhance osteogenic differentiation via Notch signaling Nanoscale Advances. 2024.
32. Stellpflug A, Caron J, Fasciano S, Wang B, Wang S. Bone-derived nanoparticles (BNPs) enhance osteogenic differentiation <i>via</i> Notch signaling. Nanoscale Adv. 2025 Jan 28;7(3):735-747. PMCID: PMC11734751
33. Stellpflug A, Joshi A, Wang S, Gu L, Wu R, Wang B. Image-guided in vivo evaluation and comparison of bone-targeting peptides for therapeutic intervention. Drug Deliv Transl Res. 2026 May;16(5):1547-1560.
34. Wang S, Zhai SP, Wang B, Yan Y, Gong X, Liang Z, Medina G, Mak D, Caron J, Mak M. Nanoparticle-mediated bone regeneration: From molecular mechanisms to clinical translation. J Control Release. 2026 Jan 10;389:114409.
35. Stellpflug A, Keener K, Nguyen C, Gasparetti T, Joshi A, Gu L, Wang S, Wu R, Lin K, Shakir S, Wang B.. Optimizing release dynamics of bone-derived nanoparticles for enhanced in vivo fluorescence monitoring and bone regeneration in craniofacial repair Biofabrication. Stellpflug A, Keener K, Nguyen C, Gasparetti T, Joshi A, Gu L, Wang S, Wu R, Lin K, Shakir S, Wang B. Optimizing release dynamics of bone-derived nanoparticles for enhanced in vivo.