CURRICULUM VITAE
Chien-Wei Lin PhD
Chien-Wei Lin PhD
Associate Professor
Department of Data Science Institute
Division of Biostatistics
Department of Data Science Institute
Division of Biostatistics
OFFICE ADDRESS: |
Medical Education Building |
8701 Watertown Plank Rd |
Milwaukee, WI 53226 |
Phone: 414-955-8150 |
Email: chlin@mcw.edu |
EDUCATION: |
09/01/2000 - 06/30/2005 B.S., National Tsing Hua University, Hsinchu, Taiwan |
09/01/2005 - 06/30/2007 M.S., National Chiao Tung University, Hsinchu, Taiwan |
08/27/2012 - 04/30/2017 Ph.D., University of Pittsburgh, Pittsburgh, PA |
FACULTY APPOINTMENTS: |
08/01/2017 - Present Adjunct Assistant Professor, Department of Mathematical Sciences, University of Wisconsin - Milwaukee, WI |
08/01/2017 - Present Assistant Professor, Biostatistics, Medical College of Wisconsin, WI |
AWARDS AND HONORS: |
12/2003 Academic Achievement Award, The National Tsing Hua University |
09/2006 Academic Achievement Award, The National Chiao Tung University |
07/2007 Chen Wen-Chen Memorial Scholarship in Statistical Sciences, Professor Chen Wen-Chen’s Memorial Foundation |
04/2014 Best ENAR Presentation Award, University of Pittsburgh |
04/2015 Health Disparities Poster Competition Award, University of Pittsburgh |
07/2015 CCNS Opening Workshop Travel Award, Statistical and Applied Mathematical Sciences Institute (SAMSI) |
08/2015 CCNS Summer School Travel Award, Statistical and Applied Mathematical Sciences Institute (SAMSI) |
03/2016 Distinguished Student Paper Award, International Biometric Society Eastern North American Region (ENAR) |
04/2016 Best ENAR Presentation Award, University of Pittsburgh |
05/2016 Challenges in Computational Neuroscience (CCNS) Transition Workshop Travel Award, Statistical and Applied Mathematical Sciences Institute (SAMSI) |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
03/01/2015 - Present American Statistical Association (Member) |
10/01/2015 - Present International Biometric Society Eastern North American Region (Member) |
04/30/2018 - Present Medical College of Wisconsin Genomic Sciences and Precision Medicine Center (Member) |
06/01/2018 - Present International Chinese Statistical Association (Member) |
11/27/2018 - Present Medical College of Wisconsin (MCW) Cancer Center (Member) |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
Chien-Wei Lin, George Tseng, SeqDesign: A framework for RNA-Seq genome-wide power Mar 2014/Mar 2016
calculation and experimental design issues, ENAR 2016, Austin, TX, 03/2016 |
Chien-Wei Lin, George Tseng, RNASeqDesign: A framework for RNA-Seq genome-wide power calculation and study design issues, ICSA 2018 Applied Statistics Symposium, New Brunswick, NJ, 06/14/2018 - 06/17/2018 |
Chien-Wei Lin, George Tseng, RNASeqDesign: A framework for RNA-Seq genome-wide power calculation and study design issues, ICSA China Conference, Qingdao, Shandong, China, 07/02/2018 - 07/06/2018 |
Chien-Wei Lin, George Tseng, RNASeqDesign: A framework for RNA-Seq genome-wide power calculation and experimental design issues, LIDS 2019, Pittsburgh, PA, 05/29/2019 - 05/31/2019 |
Chien-Wei Lin, Peng Liu, George Tseng, RNA-seq and Methyl-seq power calculation and design issue, ICSA 2019 Applied Symposium, Raleigh Convention Center, NC, 06/09/2019 - 06/12/2019 |
Chien-Wei Lin, George C. Tseng, RNASeqDesign: A framework for RNA-Seq genome-wide power calculation and experimental design issues., MCP 2019 Meeting, Taipei, Taiwan, 12/12/2019 - 12/15/2019 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
International |
SeqDesign: A framework for RNA-Seq genome-wide power calculation and experimental design issues. Contributed, ENAR, Baltimore, MD, 03/2014 |
Comparative Pathway Integrator: a framework of multiple transcriptomic studies for
consensual and differential pathway analysis, Joint Statistical Meetings, Seattle, WA, 08/2015 |
Steven Henle, Chien-Wei Lin, Brian Link, Identifying the molecular roll for MFRP in human iPSC derived RPE maturation, ARVO 2018 Annual Meeting, Honolulu, Hawaii, 04/29/2018 - 05/03/2018 |
Yuliya S. Nikolova, Chien-Wei Lin, Arin Bakht, Aristotle N. Voineskos, Ahmad R. Hariri, Etienne Sibille, Polygenic risk for accelerated molecular brain aging is associated with increased depressive symptoms and blunted corticolimbic circuit reactivity, SOBP, New York City, New York, 05/10/2018 - 05/12/2018 |
Steven Henle, Chien-Wei Lin, Brian Link, Identifying the molecular roll for MFRP in human iPSC derived RPE maturation, Gordon Research Conference on Visual System Development, Lucca (Barga), IT, 05/20/2018 - 05/25/2018 |
Chien-Wei Lin, George Tseng, Adaptive weighting methods for identifying concordant differentially expressed genes in omics meta-analysis, ENAR 2019 Meeting, Philadelphia, PA, 03/24/2019 - 03/27/2019 |
Gabrielle C. Geddes, Chien-Wei Lin, Kathleen Mussatto, Aoy Tomita-Mitchell, Ciliopathy Burden and Neurodevelopmental Delay in Patients with Isolated Congenital Heart Disease, PAS 2019 Meeting, Baltimore, Maryland, 04/24/2019 - 05/01/2019 |
Ashley E. Ciecko, David M. Schauder, Bardees M. Foda, Chien-Wei Lin, Weiguo Cui, Yi-Guang Chen, Single-cell transcriptome analysis reveals diverse islet-infiltrating T cell subsets and a role for BATF in promoting the diabetogenic activity of CD8 T cells., AAI 2019 Meeting, San Diego, California, 05/09/2019 - 05/13/2019 |
Local |
Genetic Modulation of Brain Molecular Aging, Dean’s Day’s Competition, University of Pittsburgh, Pittsburgh, PA, 04/2013 |
Genetic Modulation of Brain Molecular Aging, Dean’s Day’s Competition, University of Pittsburgh, Pittsburgh, PA, 04/2014 |
SeqDesign: A framework for RNA-Seq genome-wide power calculation and experimental design issues, Pittsburgh ASA banquet, Pittsburgh, PA, 04/2015 |
Genetic Modulation of Brain Molecular Aging, Health Disparities Poster Competition, University of Pittsburgh, Pittsburgh, PA, 04/2015 |
Genetic Modulation of Brain Molecular Aging, Dean’s Day’s Competition, University of Pittsburgh, Pittsburgh, PA, 04/2015 |
SeqDesign: A framework for RNA-Seq genome-wide power calculation and experimental design issues, Pittsburgh ASA banquet, Pittsburgh, PA, 03/2016 |
DNA Methylation in the Human Frontal Cortex Reveals a Putative Mechanism for Age-by-Disease Interactions, Dean’s Day’s Competition, University of Pittsburgh, Pittsburgh, PA, 04/2016 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
08/2017 - Present Member, Biostats Computer Committee, Division of Biostatistics, Institute for Health and Equity |
01/2018 - Present Chair, Bioinformatics course development committee, Division of Biostatistics, Institute for Health and Equity |
01/2018 - 09/2018 Chair, Applied Preliminary Exam, Division of Biostatistics, Institute for Health and Equity |
01/2018 - Present Member, Fetal Concerns Scientific Committee, Fetal Concerns Center, Children's Hospital of Wisconsin |
04/2018 - 03/2019 Member, Seminar committee, Division of Biostatistics, Institute for Health and Equity |
07/01/2018 - Present Member, Graduate Studies Council Curriculum & Programs Committee |
09/2018 - Present Member, Dissertation committee of Ashley Ciecko, Department of Microbiology and Immunology |
03/2019 - 05/2020 Chair, Seminar committee, Division of Biostatistics, Institute for Health and Equity |
01/2020 - 09/2020 Chair, Applied Preliminary Exam, Division of Biostatistics, Institute for Health and Equity |
06/2020 - Present Member, Dissertation committee of Manoj Khanal, Division of Biostatistics, Institute for Health and Equity |
EXTRAMURAL TEACHING: |
Graduate Student Education |
10/2014 University of Pittsburgh, Guest lecturer of BIOST 2055 |
03/2015 University of Pittsburgh, Guest lecturer of HUGEN 2070 |
03/2015 University of Pittsburgh, Guest lecturer of BIOST 2094 |
01/09/2017 - 04/30/2017 University of Pittsburgh, Guest lecturer of BIOST 2094 |
01/15/2018 - 05/03/2018 Division of Biostatistics, MCW, Statistical Models and Methods II |
01/14/2019 - 05/01/2019 Division of Biostatistics, MCW, Statistical Genetics |
09/2019 - 12/2019 Division of Biostatistics, MCW, Statistical Models and Methods III |
PROGRAMMATIC DEVELOPMENTS: |
Educational Programs |
Faculty |
01/2018 - Present Chair, Bioinformatics course development committee, Division of Biostatistics |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Diniz BS, Reynolds CF 3rd, Sibille E, Lin CW, Tseng G, Lotrich F, Aizenstein HJ, Butters MA. Enhanced Molecular Aging in Late-Life Depression: the Senescent-Associated Secretory Phenotype. Am J Geriatr Psychiatry. 2017 Jan;25(1):64-72. PMCID: PMC5164865 |
2. Kim S, Lin CW, Tseng GC. MetaKTSP: a meta-analytic top scoring pair method for robust cross-study validation of omics prediction analysis. Bioinformatics. 2016 Jul 01;32(13):1966-73. PMCID: PMC6280887 |
3. Liang YJ, Lin YT, Chen CW, Lin CW, Chao KM, Pan WH, Yang HC. SMART: Statistical Metabolomics Analysis-An R Tool. Anal Chem. 2016 Jun 21;88(12):6334-41. |
4. Belzeaux R, Lin CW, Ding Y, Bergon A, Ibrahim EC, Turecki G, Tseng G, Sibille E. Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis. J Psychiatr Res. 2016 Oct;81:119-26. |
5. Diniz BS, Lin CW, Sibille E, Tseng G, Lotrich F, Aizenstein HJ, Reynolds CF, Butters MA. Circulating biosignatures of late-life depression (LLD): Towards a comprehensive, data-driven approach to understanding LLD pathophysiology. J Psychiatr Res. 2016 Nov;82:1-7. PMCID: PMC9344393 |
6. Grubisha MJ, Lin CW, Tseng GC, Penzes P, Sibille E, Sweet RA. Age-dependent increase in Kalirin-9 and Kalirin-12 transcripts in human orbitofrontal cortex. Eur J Neurosci. 2016 Oct;44(7):2483-2492. PMCID: PMC5048532 |
7. Nikolova YS, Iruku SP, Lin CW, Conley ED, Puralewski R, French B, Hariri AR, Sibille E. FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk. Front Psychol. 2015;6:1377. PMCID: PMC4584966 |
8. McKinney BC, Lin CW, Oh H, Tseng GC, Lewis DA, Sibille E. Hypermethylation of BDNF and SST Genes in the Orbital Frontal Cortex of Older Individuals: A Putative Mechanism for Declining Gene Expression with Age. Neuropsychopharmacology. 2015 Oct;40(11):2604-13. PMCID: PMC4569950 |
9. Lin CW, Chang LC, Tseng GC, Kirkwood CM, Sibille EL, Sweet RA. VSNL1 Co-Expression Networks in Aging Include Calcium Signaling, Synaptic Plasticity, and Alzheimer's Disease Pathways. Front Psychiatry. 2015;6:30. PMCID: PMC4353182 |
10. Chang LC, Jamain S, Lin CW, Rujescu D, Tseng GC, Sibille E. A conserved BDNF, glutamate- and GABA-enriched gene module related to human depression identified by coexpression meta-analysis and DNA variant genome-wide association studies. PLoS One. 2014;9(3):e90980. PMCID: PMC3946570 |
11. Yang HC, Lin CW, Chen CW, Chen JJ. Applying genome-wide gene-based expression quantitative trait locus mapping to study population ancestry and pharmacogenetics. BMC Genomics. 2014 Apr 29;15:319. PMCID: PMC4236814 |
12. Yang HC, Lin HC, Kang M, Chen CH, Lin CW, Li LH, Wu JY, Chen YT, Pan WH. SAQC: SNP array quality control. BMC Bioinformatics. 2011 Apr 18;12:100. PMCID: PMC3101186 |
13. Emura, T., Lin, C. W., & Wang, W.. A goodness-of-fit test for Archimedean copula models in the presence of right censoring Computational Statistics and Data Analysis. 2010 Apr 02; 54(12), 3033–3043. |
14. Yang HC, Wang PL, Lin CW, Chen CH, Chen CH. Integrative analysis of single nucleotide polymorphisms and gene expression efficiently distinguishes samples from closely related ethnic populations. BMC Genomics. 2012 Jul 28;13:346. PMCID: PMC3453505 |
15. Wang, B. C., Lin, C. W., Chen, K. T., & Chen, L. J. An analytical model for generalized ESP games. Knowledge-based systems. 2012 October; 34:114-127. |
16. Chowdhury TA, Koceja C, Eisa-Beygi S, Kleinstiver BP, Kumar SN, Lin CW, Li K, Prabhudesai S, Joung JK, Ramchandran R. Temporal and Spatial Post-Transcriptional Regulation of Zebrafish <i>tie1</i> mRNA by Long Noncoding RNA During Brain Vascular Assembly. Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1562-1575. PMCID: PMC6023729 |
17. Ma T, Huo Z, Kuo A, Zhu L, Fang Z, Zeng X, Lin CW, Liu S, Wang L, Liu P, Rahman T, Chang LC, Kim S, Li J, Park Y, Song C, Oesterreich S, Sibille E, Tseng GC. MetaOmics: analysis pipeline and browser-based software suite for transcriptomic meta-analysis. Bioinformatics. 2019 May 01;35(9):1597-1599. PMCID: PMC6499246 |
18. Chien-Wei Lin, Serena G. Liao, Peng Liu, Mei‐Ling Ting Lee, Yong Seok Park, George C. Tseng. RNASeqDesign: a framework for ribonucleic acid sequencing genomewide power calculation and study design issues Journal of the Royal Statistical Society. Series C, Applied statistics. . |
19. McKinney BC, Lin CW, Rahman T, Oh H, Lewis DA, Tseng G, Sibille E. DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions. Transl Psychiatry. 2019 Jan 29;9(1):39. PMCID: PMC6351569 |
20. Liu P, Lin CW, Park Y, Tseng G. MethylSeqDesign: a framework for Methyl-Seq genome-wide power calculation and study design issues. Biostatistics. 2021 Jan 28;22(1):35-50. PMCID: PMC7846147 |
21. Samudrala SSK, North LM, Stamm KD, Earing MG, Frommelt MA, Willes R, Tripathi S, Dsouza NR, Zimmermann MT, Mahnke DK, Liang HL, Lund M, Lin CW, Geddes GC, Mitchell ME, Tomita-Mitchell A. Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction. Mol Genet Genomic Med. 2020 Apr;8(4):e1152. PMCID: PMC7196453 |
22. Wu PK, Hong SK, Chen W, Becker AE, Gundry RL, Lin CW, Shao H, Gestwicki JE, Park JI. Mortalin (HSPA9) facilitates <i>BRAF</i>-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability. Sci Signal. 2020 Mar 10;13(622). PMCID: PMC7099430 |
23. Pan P, Zhu Z, Oshima K, Aldakkak M, Tsai S, Huang YW, Dong W, Zhang J, Lin CW, Wang Y, Yearsley M, Yu J, Wang LS. Black raspberries suppress pancreatic cancer through modulation of NKp46<sup>+</sup>, CD8<sup>+</sup>, and CD11b<sup>+</sup> immune cells. Food Front. 2020 Mar;1(1):70-82. PMCID: PMC7197210 |
24. Lin, C.W., Chang, L. C., …, Tseng, G. C., Sibille, E.. (2020). Older Molecular Brain Age in Severe Mental Illness. Molecular Psychiatry, In press. |
25. Zeng, X., Zong, W., Lin, C. W., Fang, Z., Ma, T., Lewis, D., Enwright, J., Tseng, G.C.. (2020). Comparative Pathway Integrator: a framework of meta-analytic integration of multiple transcriptomic studies for consensual and differential pathway analysis. Genes. In press. |
26. Li, Y., Zeng, X., Lin, C. W.^, Tseng, G.C^.. Simultaneous Estimation of Number of Clusters and Feature Sparsity Parameter in Clustering High-Dimensional Data. Biometrics. Under revision. |
27. Zeng X, Zong W, Lin CW, Fang Z, Ma T, Lewis DA, Enwright JF, Tseng GC. Comparative Pathway Integrator: A Framework of Meta-Analytic Integration of Multiple Transcriptomic Studies for Consensual and Differential Pathway Analysis. Genes (Basel). 2020 Jun 24;11(6). PMCID: PMC7348908 |
28. Lin CW, Chang LC, Ma T, Oh H, French B, Puralewski R, Mathews F, Fang Y, Lewis DA, Kennedy JL, Mueller D, Marshe VS, Jaffe A, Chen Q, Ursini G, Weinberger D, Newman AB, Lenze EJ, Nikolova YS, Tseng GC, Sibille E. Older molecular brain age in severe mental illness. Mol Psychiatry. 2021 Jul;26(7):3646-3656. PMCID: PMC7785531 |
29. Gartz M, Lin CW, Sussman MA, Lawlor MW, Strande JL. Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy. Dis Model Mech. 2020 Nov 13;13(11). PMCID: PMC7673361 |
30. Huang YW, Lin CW, Pan P, Shan T, Echeveste CE, Mo YY, Wang HT, Aldakkak M, Tsai S, Oshima K, Yearsley M, Xiao J, Cao H, Sun C, Du M, Bai W, Yu J, Wang LS. Black Raspberries Suppress Colorectal Cancer by Enhancing Smad4 Expression in Colonic Epithelium and Natural Killer Cells. Front Immunol. 2020;11:570683. PMCID: PMC7793748 |
31. Xin G, Chen Y, Topchyan P, Kasmani MY, Burns R, Volberding PJ, Wu X, Cohn A, Chen Y, Lin CW, Ho PC, Silverstein R, Dwinell MB, Cui W. Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer. Cancer Immunol Res. 2021 Apr;9(4):454-469. PMCID: PMC8137571 |
32. Huang YW, Lin CW, Pan P, Echeveste CE, Dong A, Oshima K, Yearsley M, Yu J, Wang LS. Dysregulated Free Fatty Acid Receptor 2 Exacerbates Colonic Adenoma Formation in <i>Apc</i> <sup><i>Min/+</i></sup> Mice: Relation to Metabolism and Gut Microbiota Composition. J Cancer Prev. 2021 Mar 30;26(1):32-40. PMCID: PMC8020170 |
33. Li Y, Zeng X, Lin CW, Tseng GC. Simultaneous estimation of cluster number and feature sparsity in high-dimensional cluster analysis. Biometrics. 2022 Jun;78(2):574-585. |
34. Lin CW, Liao SG, Liu P, Park YS, Lee MT, Tseng GC. RNASeqDesign: A framework for RNA-Seq genome-wide power calculation and study design issues. J R Stat Soc Ser C Appl Stat. 2019 Apr;68(3):683-704. PMCID: PMC7941184 |
35. Huang YW, Pan P, Echeveste CE, Wang HT, Oshima K, Lin CW, Yearsley M, Xiao J, Chen J, Sun C, Yu J, Wang LS. Transplanting fecal material from wild-type mice fed black raspberries alters the immune system of recipient mice. Food Front. 2020 Sep;1(3):253-259. PMCID: PMC8301209 |
36. Wang S, Lin CW, Carleton AE, Cortez CL, Johnson C, Taniguchi LE, Sekulovski N, Townshend RF, Basrur V, Nesvizhskii AI, Zou P, Fu J, Gumucio DL, Duncan MC, Taniguchi K. Spatially resolved cell polarity proteomics of a human epiblast model. Sci Adv. 2021 Apr;7(17). PMCID: PMC8064645 |
37. Ciecko AE, Schauder DM, Foda B, Petrova G, Kasmani MY, Burns R, Lin CW, Drobyski WR, Cui W, Chen YG. Self-Renewing Islet TCF1<sup>+</sup> CD8 T Cells Undergo IL-27-Controlled Differentiation to Become TCF1<sup>-</sup> Terminal Effectors during the Progression of Type 1 Diabetes. J Immunol. 2021 Oct 15;207(8):1990-2004. PMCID: PMC8492517 |
38. Huang YW, Mo YY, Echeveste CE, Oshima K, Zhang J, Yearsley M, Lin CW, Yu J, Liu P, Du M, Sun C, Xiao J, Wang LS. Black raspberries attenuate colonic adenoma development in <i>Apc</i> <sup><i>Min</i></sup> mice: Relationship to hypomethylation of promoters and gene bodies. Food Front. 2020 Sep;1(3):234-242. PMCID: PMC8457619 |
39. Fang S, Wu J, Reho JJ, Lu KT, Brozoski DT, Kumar G, Werthman AM, Silva SD Jr, Muskus Veitia PC, Wackman KK, Mathison AJ, Teng BQ, Lin CW, Quelle FW, Sigmund CD. RhoBTB1 reverses established arterial stiffness in angiotensin II-induced hypertension by promoting actin depolymerization. JCI Insight. 2022 May 09;7(9). PMCID: PMC9090250 |
40. Vedi M, Nalabolu HS, Lin CW, Hoffman MJ, Smith JR, Brodie K, De Pons JL, Demos WM, Gibson AC, Hayman GT, Hill ML, Kaldunski ML, Lamers L, Laulederkind SJF, Thorat K, Thota J, Tutaj M, Tutaj MA, Wang SJ, Zacher S, Dwinell MR, Kwitek AE. MOET: a web-based gene set enrichment tool at the Rat Genome Database for multiontology and multispecies analyses. Genetics. 2022 Apr 04;220(4). PMCID: PMC8982048 |
41. Dong A, Lin CW, Echeveste CE, Huang YW, Oshima K, Yearsley M, Chen X, Yu J, Wang LS. Protocatechuic Acid, a Gut Bacterial Metabolite of Black Raspberries, Inhibits Adenoma Development and Alters Gut Microbiome Profiles in <i>Apc</i> <sup><i>Min</i>/+</sup> Mice. J Cancer Prev. 2022 Mar 30;27(1):50-57. PMCID: PMC8984655 |
42. Zenga J, Atkinson S, Yen T, Massey B, Stadler M, Bruening J, Peppard W, Reuben M, Hayward M, Mesich B, Buchan B, Ledeboer N, Sanchez JL, Fraser R, Lin CW, Holtz ML, Awan M, Wong SJ, Puram SV, Salzman N. A phase 2 trial of a topical antiseptic bundle in head and neck cancer surgery: Effects on surgical site infection and the oral microbiome. EBioMedicine. 2022 Jul;81:104099. PMCID: PMC9168040 |
43. Dong A, Pan X, Lin CW, Huang YW, Krause H, Pan P, Baim A, Thomas MJ, Chen X, Yu J, Michaelis L, Liu P, Wang LS, Atallah E. A Pilot Clinical Study to Investigate the Hypomethylating Properties of Freeze-dried Black Raspberries in Patients with Myelodysplastic Syndrome or Myeloproliferative Neoplasm. J Cancer Prev. 2022 Jun 30;27(2):129-138. PMCID: PMC9271408 |
44. Khatun A, Kasmani MY, Zander R, Schauder DM, Snook JP, Shen J, Wu X, Burns R, Chen YG, Lin CW, Williams MA, Cui W. Single-cell lineage mapping of a diverse virus-specific naive CD4 T cell repertoire. J Exp Med. 2021 Mar 01;218(3). PMCID: PMC7676493 |
45. Ciecko AE, Wang Y, Harleston S, Drewek A, Serreze DV, Geurts AM, Lin CW, Chen YG. Heterogeneity of Islet-Infiltrating IL-21+ CD4 T Cells in a Mouse Model of Type 1 Diabetes. J Immunol. 2023 Apr 01;210(7):935-946. PMCID: PMC10483376 |
46. Alvarez-Argote S, Paddock SJ, Flinn MA, Moreno CW, Knas MC, Almeida VA, Buday SL, Bakhshian Nik A, Patterson M, Chen YG, Lin CW, O'Meara CC. IL-13 promotes functional recovery after myocardial infarction via direct signaling to macrophages. JCI Insight. 2024 Jan 23;9(2). PMCID: PMC10906228 |
47. Jing X, Jia S, Teng M, Day BW, Afolayan AJ, Jarzembowski JA, Lin CW, Hessner MJ, Pritchard KA Jr, Naylor S, Konduri GG, Teng RJ. Cellular Senescence Contributes to the Progression of Hyperoxic Bronchopulmonary Dysplasia. Am J Respir Cell Mol Biol. 2024 Feb;70(2):94-109. |
48. Kasmani MY, Topchyan P, Brown AK, Brown RJ, Wu X, Chen Y, Khatun A, Alson D, Wu Y, Burns R, Lin CW, Kudek MR, Sun J, Cui W. A spatial sequencing atlas of age-induced changes in the lung during influenza infection. Nat Commun. 2023 Oct 18;14(1):6597. PMCID: PMC10584893 |
49. Wang T, Lin CW. Using a centered general linear model for detection of interactions among biomarkers. Stat Methods Med Res. 2024 Mar;33(3):414-432. |
50. Sekulovski N, Wettstein JC, Carleton AE, Juga LN, Taniguchi LE, Ma X, Rao S, Schmidt JK, Golos TG, Lin CW, Taniguchi K. Temporally resolved early BMP-driven transcriptional cascade during human amnion specification. bioRxiv. 2024 Mar 06. PMCID: PMC10942271 |
51. Nikola SekulovskiJenna C. WettsteinAmber E. CarletonLinnea E. TaniguchiXiaolong MaSridhar RaoJenna K. SchmidtThaddeus G. GolosChien-Wei LinKenichiro Taniguchi. Temporally resolved early BMP-driven transcriptional cascade during human amnion specification eLife. Sekulovski N, Wettstein JC, Carleton AE, Taniguchi LE, Ma X, Rao S, Schmidt JK Golos TG Lin CW, Taniguchi K (2023) Temporally resolved early BMP-driven transcriptional cascade duri. |
52. . Identification of Amnion Progenitor-Like Cells at the Amnion-Epiblast Boundary in the Primate Peri-Gastrula . Sekulovski N, Juga L, Cortez CL, Czerwinski M, Whorton AE, Spence JR, Schmidt JK, Golos TG, Gumucio DL, Lin CW, Taniguchi K (2023) Identification of Amnion Progenitor-Like Cells at. |
53. Sekulovski N, Wettstein JC, Carleton AE, Juga LN, Taniguchi LE, Ma X, Rao S, Schmidt JK, Golos TG, Lin CW, Taniguchi K. Temporally resolved early BMP-driven transcriptional cascade during human amnion specification. bioRxiv. 2024 Mar 06. PMCID: PMC10942271 |
54. . Temporally resolved early BMP-driven transcriptional cascade during human amnion specification (Reviewed Preprint)
. Sekulovski N, Wettstein JC, Carleton AE, Taniguchi LE, Ma X, Rao S, Schmidt JK, Golos TG, Lin CW, Taniguchi K (2023) Temporally resolved early BMP-driven transcriptional cascade du. |
55. Pant T, Lin CW, Bedrat A, Jia S, Roethle MF, Truchan NA, Ciecko AE, Chen YG, Hessner MJ. Monocytes in type 1 diabetes families exhibit high cytolytic activity and subset abundances that correlate with clinical progression. Sci Adv. 2024 May 17;10(20):eadn2136. PMCID: PMC11100571 |
56. Kemmo Tsafack U, Ahn KW, Kwitek AE, Lin CW. Meta-Analytic Gene-Clustering Algorithm for Integrating Multi-Omics and Multi-Study Data. Bioengineering (Basel). 2024 Jun 08;11(6). PMCID: PMC11201102 |
57. Chen W, Song YS, Lee HS, Lin CW, Lee J, Kang YE, Kim SK, Kim SY, Park YJ, Park JI. Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks. Oncogene. 2024 Jul;43(31):2431-2446. |
58. Sekulovski N, Carleton AE, Rengarajan AA, Lin CW, Juga LN, Whorton AE, Schmidt JK, Golos TG, Taniguchi K. Temporally resolved single cell transcriptomics in a human model of amniogenesis. bioRxiv. 2024 Aug 22. PMCID: PMC11257495 |
