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CURRICULUM VITAE

Christine Hogan MD
Assistant Professor
Department of Medicine
Division of Infectious Disease

OFFICE ADDRESS:
Froedtert East Clinics
9200 W Wisconsin Ave
Milwaukee, WI 53226

EDUCATION:
1990 A.B., Harvard University, Cambridge, Massachusetts
1995 M.D., University of California, San Francisco; San Francisco, California

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/1995 - 06/1998 Internship and Residency in Internal Medicine, Primary Care, Massachusetts General Hospital, Boston, MA
07/1998 - 06/2001 Fellowship in Infectious Diseases, Columbia University College of Physicians and Surgeons; New York Presbyterian Hospital, New York, NY

FACULTY APPOINTMENTS:
07/2001 - 07/2005 Instructor in Clinical Medicine, Columbia University, Division of Infectious Diseases, New York, NY
07/2001 - 07/2006 Associate Physician, The Rockefeller University Hospital, New York, NY
07/2001 - 06/2004 Clinical Scholar/Research Associate, Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY
07/2001 - 08/2006 Assistant Attending, New York Presbyterian Hospital, New York, NY
07/2005 - 08/2006 Assistant Professor in Clinical Medicine, Columbia University, Division of Infectious Diseases, New York, NY
08/2006 - Present Adjunct Assistant Professor in Clinical Medicine, Columbia University College of Physicians and Surgeons, Division of Infectious Diseases, New York, NY
03/2008 - Present Assistant Professor of Medicine, Division of Infectious Diseases-ARCW Medical College of Wisconsin, Milwaukee, WI

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
Internal Medicine (working on recert)
1998
12/2008
Infectious Diseases
2000
2021
   
Licensure
Number Issue DateExpiration
Licensed in Medicine, New York
1998
None
Wisconsin License
2008
None
    

AWARDS AND HONORS:
1986 - 1990 John Harvard and Elizabeth Cary Agassiz Scholarship
1987 Detur Award for Outstanding Freshman Performance, Harvard College
1989 Phi Beta Kappa, Inducted Junior Year College
1990 Magna Cum Laude Senior Thesis, "The Medical Model of Knowledge in George Eliot's Middlemarch and H.G. Wells' Tono-Bungay
1995 UCSF Alumni Association's Award for Academic Excellence
1995 Alpha Omega Alpha Member
2000 GSK Junior Faculty Award- Infectious Diseases
2005 Ewig Clinical Education Award for outstanding teaching, Columbia University College of Physicians and Surgeons (to provide 3 years of salary support)
2006 Nominee, Teacher of the Year award by the Columbia University College of Physicians and Surgeons class of 2008, New York City.
2006 Honoree, American Medical Women's Association, Columbia University, New York City, for contributions to gender equity in medicine.
2006 Nominee, Daniel V. Kimberg Memorial Junior Faculty Teaching Award, Columbia University College of Physicians and Surgeons, New York City.
2015 Selected as one of Milwaukee’s Top Doctors in Infectious Disease, As published in Milwaukee Magazine, August 2015
2016 Selected as one of Milwaukee’s Top Doctors in Infectious Disease, As published in Milwaukee Magazine, August, 2016 in peer-review process compiled by Castle Connolly Medical, Ltd.

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1989 - Present Phi Beta Kappa
1995 - Present Alpha Omega Alpha
1998 - Present American College of Physicians-American Society of Internal Medicine
2012 - Present Infectious Diseases Society of America/HIV Medicine Association
2016 - Present American Academy of HIV Medicine

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Prior
Peer Review
Title:
Acute and Early HIV-1 Infection
Source:
NIAID-funded AIEDRP Grant
Role:
Sub-investigator at Aaron Diamond AIDS Research Center (Paid by Rockefeller University Hospital as clinical scholar)
Dates:
2001 - 2004
  
Title:
Acute Infection and Early Disease Research Program
Source:
NIAID
Role:
Co-investigator, Chairperson of multicenter study
Dates:
2004 - 2006
Direct Funds:
$35,000 (2004-05,$9,000 plus fringe; 2005-06, $2,6000 plus fringe)
  
Title:
Columbia University Division of Infectious Diseases Adult AIDS Clinical Trials Unit (AACTG) and Vaccine Trials Network (VTN)
Source:
NIAID
Role:
Sub-investigator at Columbia University
Dates:
2004 - 2006
Direct Funds:
$41,000 (2004-05, $21,000 salary from CFAR pilot grant; 2005-2006, $20,000 salary)
  
Title:
A Randomized Study of Treatment with Tenofovir DF, Emtricitabine, and Lopinavir/Ritonavir vs no Therapy in Newly Infected HIV-1 Infected Subjects to Determine whether Potent Antiretroviral Therapy Alters the Virologic Setpoint
Source:
NIAID (AIEDRP and AACTG)
Role:
Chairperson (Have continued, since leaving Columbia University, to serve as chairperson without direct funds)
Dates:
2006 - Present
  
Non-Peer Review
Title:
Late Presentation of HIV Disease in the Era of Potent Therapy: A retrospective analysis of patients who received their first diagnosis of HIV during hospitalization.
Source:
Columbia University Clinical Research Fellow, Mentor, Scott Hammer, MD
Role:
Investigator (Performed as part of clinical and research fellowship)
Dates:
1999 - 2001
  
Title:
Recognition of Acute HIV-1 Infection in the Emergency Department and Urgent Care Center: A prospective study involving counseling and testing for primary HIV infection in persons seeking care for a febrile illness in the emergency or urgent care setting.
Source:
Columbia University Clinical Research Fellow, Mentor, Scott Hammer, MD
Role:
Investigator (Performed as part of clinical and research fellowship)
Dates:
1999 - 2001
  
Title:
Phase I/II study to test safety and efficacy of SCH-C, an experimental CCR5 inhibitor, in HIV-1 infected individuals
Source:
Rockefeller University Hospital and Schering-Plough
Role:
Sub-investigator (Performed as part of clinical scholar training program)
Dates:
2001 - 2003
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
National
Christine Hogan, MD Lecture on, "Entry Inhibitors: an Update", for Physicians' Resource Network; New York, NY, 01/15/2002
Christine Hogan, MD Lecture on, "Acute HIV Infection: Case Presentation", for NY Metro HIV Grand Rounds; New York Academy of Medicine; New York, NY, 06/03/2004
Christine Hogan, MD Lecture on, "Current Treatment Guidelines" for symposium entitled "HIV 2003: Current Care Strategies", Nassau University Medical Center; Melville, NY, 06/03/2004
 

COMMITTEE SERVICE:
Hospital
01/2002 - 06/2004 Chairperson, Infection Control Committee, The Rockefeller University Hospital
03/2004 - 06/2004 Member, Medical Staff Executive Committee, The Rockefeller University Hospital
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Resident and Fellow Education
07/2010 - Present Substitute clinical preceptor for MCW infectious disease fellow at the AIDS Resource Center of Wisconsin
 

EXTRAMURAL TEACHING:
Medical Student Education
07/2004 - 07/2006 Columbia University, Course Director for "Microbiology/Infectious Diseases" component of core pathophysiology course for second-year medical students, College of Physicians and Surgeons. (Assistant Director in autumn 2004, Director in 2005. Continued as a lecturer in 2006-2007)
 
Resident and Fellow Education
11/2004 - 07/2006 Columbia University College of Physicians and Surgeons, New York City, Clinical preceptor for infectious disease fellow in the weekly HIV/ID longitudinal clinic
07/01/2012 - Present Resource Faculty for NRSA Postdoctoral Fellowship Program in HIV Prevention, Center for AIDS Intervention Research, Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. HOGAN, C., Hammer, S., "Host Determinants in HIV Infection and Disease Part 1: Cellular and Humoral Immune Responses", Ann. Intern. Med. 2001; 134:761-776.
2. HOGAN, C., Hammer, S., "Host Determinants in HIV Infection and Disease Part 2: Genetic Factors and Implications for Antiretroviral Therapeutics", Ann. Intern. Med. 2001;134:978-996
3. Louie M., HOGAN C., DiMascio M., Hurley A., Simon V., Rooney J, Ruiz N., Brun S., Sun E., Perelson A., Ho D., Markowitz M., "Determining the Relative Efficacy of Highly Active Antiretroviral Therapy", J. Infect. Dis. 2003; 187:896-900
4. Louie M., HOGAN C., Hurley A., Simon V., Chung C., Padte N., Lamy P., Flaherty J., Coakley D., Di Mascio M., Perelson A., Markowitz M., "Determining the Antiviral Activity of Tenofovir Disoproxil Fumarate in Treatment-naïve chronically HIV-1 Infected Individuals", AIDS 2003; 17:1151-1156.
5. Di Mascio M., Markowitz M., Louie M., HOGAN C., Hurley A., Chung C., Ho D., Perelson A., "Viral Blip Dynamics During Highly Active Antiretroviral Therapy", J. Virol. 2003, 77(22):12165-72
6. Mehandru S., Poles M., Tenner-Racz K., Horowitz A., Hurley A., HOGAN C., Boden D., Racz P., Markowitz M., "Primary HIV-1 Infection is Associated with Preferential Depletion of CD4+ T Lymphocytes from Effector Sites in the Gastrointestinal Tract," J. Exp. Med.2004, 200(6):761-70.
7. Mehandru S., Wrin T., Galovich J., Stiegler G., Veelar B., Hurley A., HOGAN C., Vasan S., Katinger H., Petropoulos C., Markowitz M., "Neutralization Profiles of Newly Transmitted Human Immunodeficiency Virus Type I by monoclonal Antibodies 2G12, 2FS, and 4E10", J. Virol. 2004, 78(24):14039-42
8. Di Mascio M., Markowitz, M. Louie., Hurley A., HOGAN C., Simon V., Follmann D., Ho D., Perelson A., "Dynamics of Intermittent Viremia during Highly Active Antiretroviral Therapy in Patients who Initiate Therapy during Chronic Versus Acute and Early HIV-1 Infection," J. Virol. 2004, 78(19):1056-73.
9. Shet A., Berry L., Mohri H., Mehandru S., Chung C., Kim A., Jean-Pierre P, HOGAN C., Simon V., Boden D., Markowitz M., "Tracking the Prevalence of Transmitted Antiretroviral Drug-Resistant HIV-1", JAIDS 2006, 41(4):439-446.
10. Messer, K., Vaida F., HOGAN C., "Robust Analysis of Biomarker Data with Informative Missingness using a Two-stage hypothesis Test in an HIV Treatment Interruption Trial: AIEDRP AIN503/ACTG A5217", Comtemp. Clin. Trials 2006, 27 (6):506-17
11. Markowitz M., Vaida F., Hare C.B., Boden D., Mohri H., Hecht F.M., Kalayjian R.C., Conrad A., Mildvan D., Aberg J., HOGAN C., Kilby J.M., Balfour H.H., Schafer K., Richman D., Little S. The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection. J. Infect. Dis. 2010; 201(9): 1298-302.
12. Hogan C., DeGruttola V, Sun X, Fiscus S, Del Rio C, Hare CB, Markowitz M, Connick E, Macatangay B, Tashima K, Kallungal B, Camp R, Frazier T, Daar E, Little S. “The Setpoint Study (ACTG A5217) – Effect of Immediate Versus Deferred Antiretroviral Therapy on Virologic Setpoint in Recently HIV-1-Infected Individuals.” J Infect Dis 2012: 205(1): 87-96.
 
Abstracts
1. HOGAN C., Dobkin J., Brudney K., Chiasson M., Woodward M., Hammer S., "Late Presentation of HIV Disease in the Era of Potent Therapy", First IAS Conference on HIV Pathogenisis and Treatment. July 8-11, 2001; Buenos Aires, Argentina. Abstract 315
2. HOGAN C., Hurley A, Louie M., Captan B., Chung C., Zhang L., Ho D., Markowitz M., "Treatment of Acute and Early HIV-1 Infection in 132 Subjects with PI-based Regimens", Ninth Conference on Retroviruses and Opportunistic Infections. February 24-28, 2002; Seattle, Washington. Abstract 363-M
3. Reynes J., Rouzier R., Kanouni T., Baillat V., Baroudy B., Keung A., HOGAN C., Markowitz M., Laughlin M., "SCH C: Safety and Antiretroviral Effects of a CCR5 Receptor Antagonist in HIV-1 Infected Subjects". Ninth Conference on Retroviruses and Opportunistic Infections. February 24-28, 2002; Seattle, Washington. Abstact 1-M
4. Hecht F., Holte S., Busch M., HOGAN C., Little S., Schacker T., Kilby M., Routy J., Palella F., Conway B., Margolick J., for the AIEDRP Network. "Absence of p31 Band Identifies Persons with Recent HIV Seroconversion", XIV International AIDS Conference. July 7-12, 2002; Barcelona, Spain. abstract TuPeC4885
5. HOGAN C., Louie M., Vasan S., Hurley A., Horowitz A., Chung C., Kim A., Di Mascio M., Perelson A., Ho D., Markowitz M. "Assessing the Relative Efficacy of HAART Regimens Using Early Changes in Plasma Viremia." Tenth Conference on Retroviruses and Opportunistic Infections. February 10-14, 2003, Boston, Massachusetts. Abstract 573.
6. Simon V., HOGAN C., Louie M., Vasan S., Rowe L., Hurley A., Padte N., Vanderhoeven J., Dawson K., Balfe P., Markowitz M., "Frequency of Transmitted Drug Resistance and Identification of Phylogenetic Clusters in a Homogeneous Cohort of Newly Infected Individuals". Tenth Conference on Retroviruses and Opportunistic Infections. February 10-14, 2003; Boston, Massachusetts. Abstract 504.
7. Vasan S., Siladji E., HOGAN C., Hurley A., Markowitz M., Tsuji M., "NKT Cells are Preserved in Patients Beginning HAART during Acute Infection". Eleventh Conference on Retroviruses and Opportunistic Infections. February 8-11, 2004 San Francisco, California. Abstract 245
8. HOGAN C., Hurley A., Vasan S., Mehandru S., Chung C. Markowitz M., "Treatment of Acute and Early HIV-1 Infection with Trizivir/Efavirenz". Second International Workshop on Acute HIV-1 Infection. May 3-4, 2004; Bethesda, MD. Abstract P-18.
9. Fiscus SA, Cachafeiro A., Kshatriya R., Napravnik S., Owen M., Keating S., Busch M., Little S., HOGAN C., "Comparison of 6 HIV Incidence Assays with the Less Sensitive Vironostika HIV Antibody Assay for Screening Subjects for A5217." 16th Conference on Retroviruses and Opportunistic Infections. February 2009 Montreal, Canada. Abstract V-122.
10. HOGAN C., DeGruttola V., Daar E., Sun X., Del Rio C., Fiscus S., Frazier T., Hare B., Markowitz M., Little S., "A Finite Course of ART during Early HIV-1 Infection Modestly Delays Need for Subsequent ART Initiation: ACTG A5217, the SETPOINT Study." 17th Conference on Retroviruses and Opportunistic Infections. February 16-19, 2010. San Francisco, California. Paper 134. (This paper has been submitted to a peer-reviewed journal for publication and is currently under review as of July 2011)