CURRICULUM VITAE
Cynthia A. Lien MD
Cynthia A. Lien MD
Chair, Professor
Department of Anesthesiology
Division of Administration
Department of Anesthesiology
Division of Administration
OFFICE ADDRESS: |
Froedtert East Clinics |
9200 W Wisconsin Ave |
Milwaukee, WI 53226 |
Fax: 414-259-1522 |
Email: clien@mcw.edu |
EDUCATION: |
- 1980 B.S., Brown University, Providence, RI |
- 1985 M.D., Columbia University, College of Physicians and Surgeons, New York, NY |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
1985 - 1986 Intern, Medicine, Lenox Hill Hospital, New York, NY |
1986 - 1989 Resident, Anesthesiology, Columbia Presbyterian Medical Center, New York, NY |
FACULTY APPOINTMENTS: |
1989 - 1991 Instructor in Anesthesiology, Anesthesiology, Weill Cornell Medical College, New York, NY |
1991 - 1995 Assistant Professor of Anesthesiology, Anesthesiology, Weill Cornell Medical College, New York, NY |
1993 - 1998 Lecturer, Columbia University, New York, NY |
1996 - 2003 Associate Professor of Anesthesiology, Anesthesiology, Weill Cornell Medical College, New York, NY |
2003 - 2006 Professor of Clinical Anesthesiology, Anesthesiology, Weill Cornell Medical College, New York, NY |
2006 - 2016 Professor of Anesthesiology, Weill Cornell Medical College, New York, NY |
2016 - Present Professor and John P. Kampine Chair of Anesthesiology, Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226 |
ADMINISTRATIVE APPOINTMENTS: |
1995 - 2005 Assistant Director Clinical Operations, Anesthesiology, New York Presbyterian Hospital |
1995 - 2016 Clinical Practice Committee, Anesthesiology, Weill Cornell Medical Center/New York Presbyterian Hospital |
2008 - 2016 Executive Committee, Anesthesiology, Weill Cornell Medical College/ New York Presbyterian Hospital |
2011 - 2016 Conflicts Advisory Panel, New York Presbyterian Hospital |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
1987 - 1989 Member: Education Committee, Anesthesiology, Columbia Presbyterian Medical Center |
1989 - 1985 Member: Education Committee, Anesthesiology, Weill Cornell Medical College |
1991 - 2016 Member: Resident Selection Committee, Anesthesiology, Weill Cornell Medical College |
1991 - 2016 Member: Clinical Competence Committee, Anesthesiology, Weill Cornell Medical College |
1995 - 2013 Director of Medical Education, Anesthesiology, Weill Cornell Medical College |
1998 - 2011 Cornell University Medical Center Guild, Weill Cornell Medical College |
2001 - 2016 Director: Neuroanesthesia Fellowship, Anesthesiology, Weill Cornell Medical Center |
2001 - 2016 Member: Fellowship Committee, Anesthesiology, Weill Cornell Medical Center |
2003 - 2016 Vice Chair for Academic Affairs, Anesthesiology, New York Presbyterian Hospital/Weill Cornell medical College |
2013 Participant: Review of Oromaxillofacial Surgery: Commission on Dental Accreditation, New York Presbyterian Hospital/Weill Cornell Medical College |
2013 Reviewer: GME Internal Review of the Plastic Surgery Residency, New York Presbyterian Hospital/Weill Cornell Medical College |
2013 - 2015 GME Educator Development Sub-Committee of the GMEC, New York Presbyterian Hospital/Weill Cornell Medical Center |
2013 - 2016 Residency Program Director, Anesthesiology, New York Presbyterian Hospital/Weill Cornell Medical Center |
2013 - 2016 Member: Graduate Medical Education Committee, New York Presbyterian Hospital/Weill Cornell Medical College |
2014 Medical Student Academic Advisor for ARC (Advisor, Research, Mentor, Career Advisor) Advisory Team, New York, NY |
2014 - 2016 Chair: program Evaluation Committee, Anesthesiology, New York Presbyterian Hospital/Weill Cornell Medical College |
2014 Facilitator: NYPH Annual Program Leadership Retreat, Anesthesiology, New York Presbyterian Hospital/Weill Cornell Medical College |
2014 - 2016 Annual Program Evaluation Task Force of the GMEC, New York Presbyterian Hospital/Weill Cornell Medical College |
2019 - 2020 Interim Core Anesthesiology Residency Program Director, Anesthesiology, MCWAH, Medical College of Wisconsin, Milwaukee, WI 53226 |
RESEARCH ADMINISTRATIVE APPOINTMENTS: |
1995 - 2005 Director of Clinical Research, Anesthesiology, Weill Cornell Medical College |
2014 Review Committee: MCRTP Grant Applications, Weill Cornell Medical College |
HOSPITAL STAFF PRIVILEGES: |
1989 - 1993 Assistant Attending Anesthesiologist, Anesthesiology, The New York Hospital, New York, NY |
1993 - 1998 Assistant Attending Anesthesiologist, Anesthesiology, Columbia Presbyterian Medical Center, New York, NY |
1993 - 2003 Associate Attending Anesthesiologist, Anesthesiology, The New York Hospital, New York, NY |
2003 - 2016 Attending Anesthesiologist, Anesthesiology, New York Presbyterian Hospital, New York, NY 10065 |
2016 - Present Attending Anesthesiologist, Anesthesiology, Froedtert Hospital& MCW Specialty Clinics, Milwaukee, WI 53226 |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
1990 | None | |
Licensure | Number | Issue Date | Expiration |
Wisconsin | 66717 | 2016 | None |
AWARDS AND HONORS: |
1990 - Present The Marjorie Topkins Teacher of the Year Award, Department of Anesthesiology, Weill Cornell Medical Center |
1998 - Present Elected to the Association of University Anesthesiologists |
2004 - Present American Academy of Pain Medicine Scientific Poster Award: Brewer R, Herman M, Lien CA, Lubenow T, Silverstein JH, Yarmush J. Comparison of the safety and efficacy of a patient-controlled transdermal fentanyl HCl delivery system versus an intravenous morphine pump for the treatment of postoperative pain after maj |
2008 - Present Quality Symposium on Changing Behavior and Providing Sustainable Delivery of Quality Care Award: Evans AS, Fleischut P, Kerr GE, Lien CA. Engaging housestaff in quality improvement and patient safety , NY |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
1986 - 2016 The New York State Society of Anesthesiologists |
1986 - Present International Anesthesia Research Society |
1986 - Present The American Society of Anesthesiologists |
1989 - Present Society of Neurosurgical Anesthesia and Critical Care |
1994 - 2016 New York Academy of Medicine |
1995 - Present Society for Education in Anesthesia |
1998 - Present Association of University Anesthesiologists |
2004 - Present Society for Advancement of Geriatric Anesthesiology |
2016 - Present Wisconsin Society of Anesthesiologists |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
2012 - 2014 Yearbook In Anesthesiology, Elsevier |
Ad-Hoc Reviewer |
1989 - 2006 Anesthesia & Analgesia |
1990 - 2002 Anesthesiology |
1991 - 2002 The Journal of Clinical Anesthesia |
1994 - 1997 Drugs |
1995 - 1999 The Annals of Pharmacotherapy |
1995 - 1999 The Journal of Pharmacology Technology |
1998 - 2002 Acta Anaesthesiolgica Scandinavica |
2006 - 2017 Anesthesiology |
2008 - Present British Journal of Anaesthesia |
2013 - Present Anesthesia & Analgesia |
2015 - 2016 BMC Anesthesiology, Anesth Analg Case Reports |
- 2019 Anesthesiology |
- 1991 Drugs |
- 2012 Canadian Journal of Anethesia |
- 02/1993 The New England Journal of Medicine |
- 2013 The Journal of Clinical Anesthesia |
- 2011 The Journal of Clinical Anesthesia |
- 2000 The journal of Neurosurgery |
- 2007 The Journal of Clinical Anesthesia |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Local |
C.Lien, Training the Good Clinician: Opportunities and Challenges, Milwaukee Academy of Medicine, Milwaukee, WI, - 10/2018 |
Recovery of neuromuscular function: What is adequate and how do we get there?
The neuromuscular junction: Pharmacologic applications during anesthesia, Visiting Professor, Medical College of Wisconsin, Milwaukee, WI, - 03/2006 |
Monitoring Neuromuscular Blockade: Necessary in the Era of Sugammadex?, WSA Annual Meeting, Wisconsin Dells, WI, - 09/2017 |
Regional |
New Developments in neuromuscular blockade that may change your practice
What is adequate recovery of neuromuscular function?, Visiting Professor, Wake Forest University, Winston-Salem, NC, - 05/2009 |
New developments in neuromuscular pharmacology and physiology, Visiting Professor, Mount Sinai Medical Center, New York, NY, - 05/2008 |
Future trends in anesthesia and their implication for neuromuscular blockade, Visiting Professor, Beth Israel Deaconess Hospital, Boston, MA, - 01/2005 |
New nondepolarizing muscle relaxants: Another search for the Holy Grail?, Visiting Professor, The Beth Israel Hospital, Boston, MA, - 08/1997 |
New nondepolarizing muscle relaxants, Visiting Professor, The Beth Israel Hospital, New York, NY, - 03/1997 |
New nondepolarizing muscle relaxants, Visiting Professor, University of Southern Alabama, Mobile, AL, - 10/1994 |
Delivering Value through Physician and Practice Performance
MOCA 2.0: The Rationale and Process, Practice Management 2016, San Diego, CA, - 01/2016 |
The MOC Part III Examination: Understanding the Value and Exploring other Formats., ABMS and the AMA Council on Medical Education jointly sponsored Symposium
Panel Presentation: Exploring alternative approaches to knowledge assessment in MOC Part III, Chicago, IL, - 06/2014 |
Panel Presentation: Women in Medicine, The Rhoades Event of the Liaison of the Minority Association of Pre-Medical Students Chapter and the Network of Pre-Medical Students, New York, NY, - 03/2014 |
Panel: Technology in Anesthesia Practice: Neuromuscular Monitoring: Best Practices
Mini-Workshop: Maintenance of Competency in Anesthesiology: Nuts and Bolts
Focus Session: PACU Complications: Avoiding Residual Neuromuscular Block, 67th Annual Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2013 |
Introductory Plenary: Why Physician Performance Measure Matters: Board Enterprise Perspective, ABMS Workshop of Performance Measures, Chicago, IL, - 06/2012 |
Panel: Avoiding residual neuromuscular blockade, ASA, Chicago, IL, - 10/2011 |
Lecture: When and what should I use to antagonize residual neuromuscular block?, Kentucky Society of Anesthesiologists, Current Issues in Anesthesia- 2009, Covington, KY, - 03/2009 |
Refresher Course: The neuromuscular junction: New developments that may change your practice, ASA, Orlando, FL, - 10/2008 |
Scientific Panel: Controversial and Emerging Drugs in my Clinical Practice: What I should Use or Avoid
Lecture: Sugammadex: The magic bullet for neuromuscular reversal?, 61st Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2007 |
How to publish, and not perish, as a program director, Society of Academic Anesthesiology Chairs/Association of Anesthesiology Program Directors, Seattle, WA, - 10/2006 |
Refresher Course Lecture: Rational Use of muscle relaxants, International Anesthesia Society, Orlando, FL, - 02/1994 |
Complications with the use of neuromuscular blocking agents
New Developments in our understanding of the pharmacology and physiology neuromuscular transmission, Visiting Professor, University of Colorado Health Science Center, Denver, CO, - 11/2007 |
ABA Certification and maintenance of certification, Visiting Professor, Montefiore Medical Center, New York, NY, - 04/2007 |
Refresher Course: The neuromuscular junction: Pharmacologic applications during anesthesia, ASA, San Francisco, CA, - 10/2007 |
The Awake Craniotomy: Potential Benefits and Challenges, Annual Meeting, Neuroanesthesia for the Occasional Neuroanesthesiologist: New Challenges, New Solutions, New York, NY, - 06/2006 |
Research in neuromuscular blockade: Is anything really new?
Recovery of neuromuscular function: What is adequate?, Visiting Professor, University of Alabama, School of Medicine, - 01/2005 |
PBLD: Neuromuscular Blockade in the Morbidly Obese Patient
Training the Good Clinician: Opportunities and Challenges
Intracranial Aneurysm Clipping and Coiling: They Require Different Anesthetics
Avoiding Residual Neuromuscular Blockade: Is it Necessary in the Age of Sugammadex?, California Society of Anesthesiologists, 2017 Fall Conference, Kauai, HI, - 11/2017 |
Focus Session: Avoiding residual neuromuscular block
Panel: Role of anesthetic pharmacology in improving perioperative outcomes: New neuromuscular and reversal agents, 65th Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2011 |
Lecture: Muscle relaxants for intubation, Emergency Medicine Grand Rounds, The New York Hospital- Queens, NY, - 05/1994 |
Lecture: The electroencephalogram as an intraoperative monitor
Lecture: New neuromuscular blocking agents, 20th Annual Anesthesiology Review Course, University of Alabama, Birmingham, AL, - 02/1992 |
C.Lien, Neuromuscular Transmission: What you Need to Know to Avoid Neuromuscular Transmission, American Society of Anesthesiologists, Orlando, FL, - 10/2019 |
Use of Neuromuscular Blocking and Reversal Agents: Can we do better?, Visiting Professor, Temple University, Philadelphia, PA, - 09/2019 |
Certifying the Good Clinician: Challenges, Opportunities and the Importance for Society, The Bradley E. Smith Visiting Professor, The Bradley E. Smith Vanderbilt University, School of Medicine, Nashville, TN, - 02/2017 |
Women and The Power of Negotiation, Presentation: Challenges for Women in Academic Medicine, American Society of Anesthesiologists Annual Meeting, Boston, MA, - 10/2017 |
Must I Demonstrate the Ability to Ventilate Before Administering Rocuronium?, IARS 2016 Annual Meeting and International Science Symposium, San Francisco, CA, - 05/2016 |
Focus Session: New Concepts in Postanesthesia Care.
Lecture: Residual Neuromuscular Blockade
Focus Session: Educational Requirements from Residency to Retirement
Lecture: Maintenance of Certification in Anesthesiology
Focus Session: FAER Panel: Faculty Development and Education Scholarship: They Keys to Improving Education
Lecture: How can Education Research Improve Teaching?, 69th Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2015 |
C.Lien, Panel on Women's Equity, Presentation: Equity and Equality in Education, Society for Education in Anesthesia, Denver, CO, - 04/2019 |
Training the Good Clinician: Opportunities and Challenges Elimination of Postoperative Residual Neuromuscular Blockade: Reality or a Pipe Dream, University of Chicago, 31st Annual Conference Challenges for Clinicians, Chicago, IL, - 12/2017 |
Lecture: Can we ever Eliminate Postoperative Residual Neuromuscular Blockade?
Lecture: What's New in Neuromuscular Blocking and Reversal Agents?, 21st Annual Advances in Physiology and Pharmacology in Anesthesia and Critical Care, Hilton Head Island, SC, - 10/2015 |
Lecture: Development of new neuromuscular blocking agents
Lecture: Is it possible to avoid residual neuromuscular block?, 61st Postgraduate Symposium on Anesthesiology, Kansas City, MO, - 04/2011 |
C.Lien, Training the Good Clinician: Opportunities and Challenges Monitoring Depth of Neuromuscular Blockade: Is it Necessary in the Age of Sugammadex Differences in Anesthetic Considerations for Intracranial Aneurysm Clipping and Endovascular Coiling, Arizona Society of Anesthesiologists, 44th Annual Scientific Meeting, Arizona, - 02/2018 |
C.Lien, Quantitative Neuromuscular Monitoring- More Important and More Feasible than you may Think, American Society of Anesthesiologist Annual Meeting, Virtual Format, - 10/2020 |
C.Lien, Changing Culture in an Academic Medical Center, Association of University Anesthesiologists, Chicago, IL, - 04/2018 |
Lecture: Use of the EEG in the operating room, The New York Hospital- Cornell Medical Center, New York, NY, - 09/1991 |
Lecture: New neuromuscular blocking drugs, Missouri State Society of Anesthesiologists, Annual Meeting, Kansas City, MO, - 04/1991 |
Neuromuscular Blockade: How and when should I antagonize residual paralysis?, Visiting Professor, Memorial Sloan Kettering, Cancer Center, New York, NY, - 05/2016 |
The physiology and pharmacology of neuromuscular transmission: Is anything new?, Visiting Professor, 21st Martin Helrich Lecture, Department of Anesthesiology, University of Maryland Medical Center, - 04/2008 |
Pharmacology of neuromuscular blockade, Visiting Professor, Rush Medical Center Chicago, IL, - 12/2006 |
Mini-Workshop: Maintenance of Certification in Anesthesiology: What's New?
Focus Session: Avoiding Postoperative Complications: Residual Neuromuscular Blockade, 68th Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2014 |
Panel on Pharmacology: Reversal of neuromuscular blockade, 63rd Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2009 |
Refresher Course: The neuromuscular junction: Pharmacologic applications during anesthesia, ASA, New Orleans, LA, - 10/2009 |
Miniworkshop: The nuts and bolts of MOCA, 62nd Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2008 |
Refresher Course: The neuromuscular junction: Pharmacologic applications during anesthesia, ASA, Atlanta, GA, - 10/2005 |
Awake craniotomy: Anesthetic challenges and complications, 59th Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2005 |
Panel: Anesthesia for awake c, Sun H, Menzies AO, Cole DJ, anier RJ, Fahey BGraniotomies, 56th Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2002 |
Lecture: The use of muscle relaxants in the Intensive Care Unit, Department of Pulmonary Medicine Grand Rounds, The New York Hospital-Cornell Medical Center New York, NY, - 04/1994 |
Lecture: Complete intravenous anesthesia, Post-Graduate Assembly in Anesthesiology, New York, NY, - 12/1991 |
Recovery of neuromuscular function: How much is enough?, Visiting Professor, Yale University School of Medicine, - 05/2001 |
New nondepolarizing relaxants, Visiting Professor, Harlem Hospital, New York, NY, - 03/1995 |
The rational use of muscle relaxants, Visiting Professor, Robert Wood Johnson Medical Center, New Brunswick, NJ, - 01/1995 |
ACGME Congress on the Resident Learning and Working Environment, ACGME Congress, Chicago, IL, - 03/2016 |
Focus Session: Avoiding Residual Neuromuscular Block
Mini-Workshop: The Nuts and Bolts of Maintenance of Certification, 66th Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2012 |
PBLD: The Patient with an Acute Subdural Hematoma who is on Clopidogrel and Dabigatran: preoperative Strategies for Reversal of Anticoagulation, SNACC Meeting, Washington D.C., - 10/2012 |
Lecture: New nondepolarizing muscle relaxants
Lecture: Use of nondepolarizing relaxants in the intensive care unit
Lecture: Anesthesia for carotid endarterectomy, Anesthesiology Update, The Lloyd Nolan Foundation, Hilton Head Island, SC, - 07/1999 |
Refresher Course: Muscle relaxants: The next generation, ASA, Atlanta, GA, - 10/1995 |
Panel Lecture: Intraoperative monitors of CNS Function, Post-Graduate Assembly in Anesthesiology, New York, NY, - 12/1990 |
Recovery of neuromuscular function: Is it possible to avoid pharmacologic antagonism?, Visiting Professor, New York University, New York, NY, - 09/2003 |
Recovery of neuromuscular function: How much is enough?, Visiting Professor, Columbia College of P&S, New York, NY, - 02/2001 |
Neuromuscular blockade revised, Visiting Professor, Memorial Sloan Kettering Cancer Center, New York, NY, - 01/1993 |
Changing the Paradigm: A New Approach to Assessment in Maintenance of Certification
Lecture: The MOCA minute, Faculty: 2015 MOC Summit, Raleigh, NC, - 05/2015 |
ABA Restructuring of the Certifying Examinations: The OSCE, ASA: Simulation Education Network Summit, Northwestern University, Chicago, IL, - 05/2013 |
EAB Advisory Panel: Anesthesiology Certification: Beyond the Multiple Choice Examination, Association of University Anesthesiologists, Cleveland, OH, - 05/2012 |
Focus Session: Avoiding postoperative residual neuromuscular block
Pharmacology Panel: Neuromuscular blockade: New reversal agents, 64th Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2010 |
Lecture: What is adequate recovery of neuromuscular function, American Association for Nurse Anesthetists, 69th Annual Meeting, Orlando, FL, - 08/2002 |
New nondepolarizing muscle relaxants, Visiting Professor, The New York Hospital- Downtown New York, NY, - 06/1994 |
Maintenance of certification in anesthesiology, 61st Postgraduate Assembly in Anesthesiology, New York, NY, - 12/2007 |
New nondepolarizing muscle relaxants, Visiting Professor, Mount Sinai Medical Center, New York, NY, - 02/1998 |
Learning Modalities for New Learners, ASA Industry Supporter Invitational, Schaumburg, IL, - 03/2017 |
Refresher Course: The neuromuscular junction: pharmacologic applications during anesthesia, ASA, Chicago, IL, - 10/2006 |
National |
Lecture: Choice of muscle relaxants in 1996
Lecture: New relaxants and the future of succinylcholine
Lecture: Use and Misuse of muscle relaxants in the intensive care unit, Mexican National Congress, Monterrey, Mexico, - 11/1996 |
Lecture: New muscle relaxants
Lecture: Reversal of residual neuromuscular block
Lecture: Neuromuscular block in patients with neuromuscular disease
Lecture: Use of nondepolarizing relaxants in the elderly, XXVII Congreso Mexicano de Anesthesiologia, Puerto Vallarta, Mexicon, - 11/1993 |
New nondepolarizing muscle relaxants, Visiting Professor, Queens Hospital, Kingston, Ontario, - 11/1993 |
Lecture: Clinical experience with cisatracurium
Lecture: Monitoring the depth of neuromuscular blockade
Lecture: The newest nondepolarizing neuromuscular blockers, Mexican National Congress, Queretaro, Mexico, - 11/1998 |
International |
Lecture: Avoiding Residual neuromuscular block
Lecture: Monitoring Neuromuscular Function
Lecture: How to Present a Case, Salzburg Cornell Seminars, Salzburg, Austria, - 03/2013 |
Lecture: Anesthesia for carotid endarterectomy
Lecture: Recovery of neuromuscular function: How much is enough?
Lecture: Anesthesia for intracranial aneurysms
Lecture: Anesthesia for carotid endarterectomy, Salzburg Cornell Seminars: Coordinator, Salburg, Austria, - 10/2000 |
Lecture: Neuroanesthesia and monitoring for neurosurgery, International Congress of Neurosurgery, Moscow, Russia, - 06/1991 |
Lecture: Neuromuscular blockade in the elderly: Dosing paradigms reconsidered, Perioperative Care for the Geriatric Patient, Prague, Czechoslovakia, - 06/2009 |
Lecture: Anesthesia for intracranial aneurysms, Cornell-Salzburg Seminars via Teleconference, Salzburg, Austria, - 10/1997 |
Lecture: Use of neuromuscular blocking agents in the United States, 9th International Expert Meeting on Neuromuscular Physiology and Pharmacology, Coupling Muscle and Nerve, Munich, Germany, - 07/2009 |
Lecture: Anesthesia for clipping of intracranial aneurysms
Lecture: Crisis management and anesthetic mishaps: Influence of human factors
Lecture: Recovery of neuromuscular function: What is adequate?
Lecture: The impact of work hour requirements on one anesthesia residency, Salzburg Cornell Seminars, Salzburg, Austria, - 08/2004 |
Lecture: Use of the processed electroencephalogram as a monitor of intraoperative neurologic function
Lecture: Muscle relaxants in Neuroanesthesia
Lecture: Anesthetics and neurosurgery
Lecture: Hypothermia and its potential clinical use, Salzburg Cornell Seminars, Salzburg, Austria, - 05/1995 |
Lecture: Nondepolarizing neuromuscular block, 1994 Update in Anesthesiology, San Juan, PR, - 04/1994 |
Evaluation of the candidate for ABA Certification, European Society of Anesthesiologists, Madrid, Spain, - 06/2006 |
Lecture: Determining adequacy of return of neuromuscular function
Lecture: New developments in understanding neuromuscular function
Lecture: Anesthesia for geriatric patients
Lecture: Postoperative cognitive function in geriatric patients, Weill Cornell Seminar in Salzburg, Salzburg, Austria |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
Local |
Navigating the Hierarchy and Replacing patriarchy., M1M2 Dinner Discussion Panelist, Medical College of Wisconsin, Milwaukee, WI, - 02/2019 |
Planning Committee and Presentation Judge, Virtual Anesthesia Resident Conference, Zoom Meeting, - 06/2020 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
2016 - Present Board of Directors, MCW Master of Science in Anesthesia Program, Medical College of Wisconsin |
2016 - Present Member, Executive Committee of the Faculty, Medical College of Wisconsin |
2016 - Present Member, Clinical Chairs Committee, Medical College of Wisconsin |
2017 - Present Member, Comprehensive Pain Steering Committee, Froedtert & Medical College of Wisconsin |
2017 - 2019 Member, MCP Quality Committee, Medical College of Physicians |
2017 - Present Member, Medical College of Physicians Compensation Committee, Medical College of Physicians |
2018 - 2019 Member, Council for Women's Advocacy, Medical College of Wisconsin |
2019 - Present Member, Joint Strategic Planning Committee, Froedtert & Medical College of Wisconsin |
2019 - Present Member, Medical College of Physicians Finance Committee, Medical College of Physicians |
2019 - Present CTSI: Ensemble Steering Committee, Medical College of Wisconsin |
2019 - Present Member, Froedtert & MCW Market Development and Growth Committee, Froedtert & Medical College of Wisconsin |
2020 - Present Advisory Board, F&MCW Clinically Integrated Network, Froedtert & Medical College of Wisconsin |
2020 - Present Board of Trustees, Finance Committee, Medical College of Wisconsin |
2020 - Present Member, Medical College of Physicians Board, Medical College of Physicians |
2020 - Present Member, MCP Q4 Committee, Medical College of Physicians |
2020 - Present Board of Managers Member, Medicare Shared Saving Program Accountable Care Organization (MSSP ACO), Froedtert & Medical College of Wisconsin |
Hospital |
2016 - Present Member, Hospital Advisory Committee, Froedtert Memorial Lutheran Hospital |
2017 - 2020 Member, Surgical Services Leadership Committee, Froedtert Memorial Lutheran Hospital |
2017 - Present Co-Chair, Surgery Council, Froedtert Memorial Lutheran Hospital |
2018 - 2019 Member, Journey to Operational Excellence Committee, Froedtert Memorial Lutheran Hospital |
2019 - Present Member, Finance and Operations Committee, Froedtert/Community Physicians |
2019 - Present Member, Community Physicians Board, Froedtert & Medical College of Wisconsin |
2019 - Present Member, Board of Directors, Froedtert/Community Physicians |
2020 - Present COVID Incident Command: Hospital and OR Operations Branch, Froedtert Memorial Lutheran Hospital |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Medical Students |
Monica Thomas, Medical College of Wisconsin |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Medical Students |
Rachel Kang, Weill Cornell Medical College |
Ansara Vaz, Weill Cornell Medical College, - 2013 applying for a residency in Anesthesiology, Matched in Anesthesiology at WCMC |
Zachary Hager, Weill Cornell Medical College, - 2014 applying to residency, Matched in Medicine |
Angela Li, Weill Cornell Medical College, - 2014 Applying for a residency in Anesthesiology, Matched in Anesthesiology at Duke University |
Carl Wang, Weill Cornell Medical College, - 2012 Applying for Residency in Anesthesiology, Matched in Anesthesiology at UCLA |
Marissa Wise, Weill Cornell Medical College, - 2013 Applying for residency in Anesthesiology, Matched in Anesthesiology at Mount Sinai |
Yifan Xu, PhD, Weill Cornell Medical College, - 2016 Applying for a residency in Anesthesiology |
Pallavi Mishra, Weill Cornell Medical College, - 2019 |
Casey Chai, Weill Cornell Medical College, - 2015 applying for a residency in Anesthesiology, Matched in Anesthesiology at WCMC |
Jie Min, Weill Cornell Medical College, - 2017 Applying for a residency in Anesthesiology |
Clinical/Research Fellows |
Robert Stout, MD, Yale University, 07/1993 - 06/1994 Neuromuscular Pharmacology, Assistant Professor |
Norbert Topf, MD, PhD, Anesthesia Associates of New Mexico, 07/2000 - 06/2001 Neuroanesthesia, Physician |
Takahiro Suzuki, MD, PhD, Surugadai Nihon University Hospital, 07/2001 - 06/2002 Neuromuscular Pharmacology, Chair |
Kane O. Pryor, MB, BS, Weill Cornell Medical College, 10/2003 - 09/2004 Neuroanesthesia, Associate Professor of Clinical Anesthesiology & Director of Clinical Research & Education |
Scott Solomon, MD, Private Practice, 07/2006 - 06/2007 Neuroanesthesia, Faculty |
Alex Proekt, MD, PhD, University of Pennsylvania, 07/2010 - 06/2011 Neuroanesthesia/Research Scholar, Assistant Professor |
H. Sachdev, MD, Anesthesiology Consultants, 07/2010 - 06/2011 Neuroanesthesia, Staff Physician |
Kingsley Storer, MB, BS, Weill Cornell Medical College, 07/2011 - 06/2012 Neuroanesthesia/Research Scholar, Assistant Professor |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Stone JG, Young WL, Khambatta HJ, Lien CA, Hsu DT, Solomon RA, Smith CR. Effect of massive intraoperative thiopental loading on cardiovascular hemodynamics and myocardial performance. J Neurosurg Anesthesiol. 1991 Jun;3(2):132-5. |
2. Lien CA, Matteo RS, Ornstein E, Schwartz AE, Diaz J. Distribution, elimination, and action of vecuronium in the elderly. Anesth Analg. 1991 Jul;73(1):39-42. |
3. Wasnick JD, Lien CA, Rubin LA, Fraser RA. Unexplained bradycardia during craniotomy closure: the role of intracranial hypotension. Anesth Analg. 1993 Feb;76(2):432-3. |
4. Kelly RE, Lien CA, Savarese JJ, Belmont MR, Hartman GS, Russo JR, Hollmann C. Depression of neuromuscular function in a patient during desflurane anesthesia. Anesth Analg. 1993 Apr;76(4):868-71. |
5. Lien CA, Gadalla F, Kudlak TT, Embree PB, Sharp GJ, Savarese JJ. The effect of ondansetron on atracurium-induced neuromuscular blockade. J Clin Anesth. 1993;5(5):399-403. |
6. Lien CA, Schmith VD, Embree PB, Belmont MR, Wargin WA, Savarese JJ. The pharmacokinetics and pharmacodynamics of the stereoisomers of mivacurium in patients receiving nitrous oxide/opioid/barbiturate anesthesia. Anesthesiology. 1994 Jun;80(6):1296-302. |
7. Belmont MR, Lien CA, Quessy S, Abou-Donia MM, Abalos A, Eppich L, Savarese JJ. The clinical neuromuscular pharmacology of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia. Anesthesiology. 1995 May;82(5):1139-45. |
8. Lien CA, Belmont MR, Abalos A, Eppich L, Quessy S, Abou-Donia MM, Savarese JJ. The cardiovascular effects and histamine-releasing properties of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia. Anesthesiology. 1995 May;82(5):1131-8. |
9. Savarese JJ, Lien CA, Belmont MR. The accuracy of the 5%-25% (T1-T3) twitch recovery interval in predicting the speed of spontaneous recovery from mivacurium-induced neuromuscular blockade. Anesth Analg. 1995 Jan;80(1):209-10. |
10. Savarese JJ, Lien CA, Belmont MR, Rubin L. The clinical and basic pharmacology of mivacurium: A short-acting nondepolarizing benzylisoquinolinium diester neuromuscular blocking drug Acta Anaesthesiologica Scandinavica, Supplement. 1995;39(106):18-22. |
11. Lien CA, Schmith VD, Belmont MR, Abalos A, Kisor DF, Savarese JJ. Pharmacokinetics of cisatracurium in patients receiving nitrous oxide/opioid/barbiturate anesthesia. Anesthesiology. 1996 Feb;84(2):300-8. |
12. Ali HH, Lien CA, Witkowski T, Brull SJ, Stout RG, Bartkowski R, Silverman DG, Patel S, Ascher JA, Goudsouzian NG. Efficacy and safety of divided dose administration of mivacurium for a 90-second tracheal intubation. J Clin Anesth. 1996 Jun;8(4):276-81. |
13. Ornstein E, Lien CA, Matteo RS, Ostapkovich ND, Diaz J, Wolf KB. Pharmacodynamics and pharmacokinetics of cisatracurium in geriatric surgical patients. Anesthesiology. 1996 Mar;84(3):520-5. |
14. Jellish WS, Lien CA, Fontenot HJ, Hall R. The comparative effects of sevoflurane versus propofol in the induction and maintenance of anesthesia in adult patients. Anesth Analg. 1996 Mar;82(3):479-85. |
15. Kisor DF, Schmith VD, Wargin WA, Lien CA, Ornstein E, Cook DR. Importance of the organ-independent elimination of cisatracurium. Anesth Analg. 1996 Nov;83(5):1065-71. |
16. Savarese JJ, Lien CA, Belmont MR. Antagonism of residual mivacurium blockade: setting the record straight. Anesthesiology. 1996 Jun;84(6):1525-8. |
17. Lien CA, Hemmings HC, Belmont MR, Abalos A, Hollmann C, Kelly RE. A comparison: the efficacy of sevoflurane-nitrous oxide or propofol-nitrous oxide for the induction and maintenance of general anesthesia. J Clin Anesth. 1996 Dec;8(8):639-43. |
18. Lien CA, Koff H, Malhotra V, Gadalla F. Emergence and extubation: a systematic approach. Anesth Analg. 1997 Nov;85(5):1177. |
19. Savarese JJ, Lien CA, Belmont MR, Wastila WB. [The clinical pharmacology of new benzylisoquinoline-diester compounds, with special consideration of cisatracurium and mivacurium]. Anaesthesist. 1997 Oct;46(10):840-9. |
20. Lien CA, Belmont MR, Wray Roth DL, Okamoto M, Abalos A, Savarese JJ. Pharmacodynamics and the plasma concentration of mivacurium during spontaneous recovery and neostigmine-facilitated recovery. Anesthesiology. 1999 Jul;91(1):119-26. |
21. Lien CA, Belmont MR, Abalos A, Hass D, Savarese JJ. The nature of spontaneous recovery from mivacurium-induced neuromuscular block. Anesth Analg. 1999 Mar;88(3):648-53. |
22. Lien CA. Combining non-depolarizing neuromuscular blocking agents: Synergism, addition or antagonism? Current Opinion in Anaesthesiology. 1999;12(4):467-471. |
23. Mack PF, Hass D, Lavyne MH, Snow RB, Lien CA. Postoperative narcotic requirement after microscopic lumbar discectomy is not affected by intraoperative ketorolac or bupivacaine. Spine (Phila Pa 1976). 2001 Mar 15;26(6):658-61. |
24. Lien CA. Regional versus general anesthesia for hip surgery in older patients: does the choice affect patient outcome? J Am Geriatr Soc. 2002 Jan;50(1):191-4. |
25. Suzuki T, Lien CA, Belmont MR, Tjan J, Savarese JJ. Edrophonium effectively antagonizes neuromuscular block at the laryngeal adductors induced by rapacuronium, rocuronium and cisatracurium, but not mivacurium. Can J Anaesth. 2003 Nov;50(9):879-85. |
26. Mack PF, Perrine K, Kobylarz E, Schwartz TH, Lien CA. Dexmedetomidine and neurocognitive testing in awake craniotomy. J Neurosurg Anesthesiol. 2004 Jan;16(1):20-5. |
27. Belmont MR, Lien CA, Tjan J, Bradley E, Stein B, Patel SS, Savarese JJ. Clinical pharmacology of GW280430A in humans. Anesthesiology. 2004 Apr;100(4):768-73. |
28. Naguib M, Lien CA, Aker J, Eliazo R. Posttetanic potentiation and fade in the response to tetanic and train-of-four stimulation during succinylcholine-induced block. Anesth Analg. 2004 Jun;98(6):1686-1691. |
29. Pryor KO, Fahey TJ 3rd, Lien CA, Goldstein PA. Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population: a randomized controlled trial. JAMA. 2004 Jan 07;291(1):79-87. |
30. Todd MM, Hindman BJ, Clarke WR, Torner JC, Intraoperative Hypothermia for Aneurysm Surgery Trial (IHAST) Investigators. Mild intraoperative hypothermia during surgery for intracranial aneurysm. N Engl J Med. 2005 Jan 13;352(2):135-45. |
31. Groudine SB, Soto R, Lien C, Drover D, Roberts K. A randomized, dose-finding, phase II study of the selective relaxant binding drug, Sugammadex, capable of safely reversing profound rocuronium-induced neuromuscular block. Anesth Analg. 2007 Mar;104(3):555-62. |
32. Lien CA, Savard P, Belmont M, Sunaga H, Savarese JJ. Fumarates: unique nondepolarizing neuromuscular blocking agents that are antagonized by cysteine. J Crit Care. 2009 Mar;24(1):50-7. |
33. Lien CA. Neostigmine: how much is necessary for patients who receive a nondepolarizing neuromuscular blocking agent? Anesthesiology. 2010 Jan;112(1):16-8. |
34. Naguib M, Kopman AF, Lien CA, Hunter JM, Lopez A, Brull SJ. A survey of current management of neuromuscular block in the United States and Europe. Anesth Analg. 2010 Jul;111(1):110-9. |
35. Kopman AF, Lien CA, Naguib M. Determining the potency of neuromuscular blockers: are traditional methods flawed? Br J Anaesth. 2010 Jun;104(6):705-10. |
36. Kopman AF, Lien CA, Naguib M. Neuromuscular dose-response studies: determining sample size. Br J Anaesth. 2011 Feb;106(2):194-8. |
37. Lien CA. Development and potential clinical impairment of ultra-short-acting neuromuscular blocking agents. Br J Anaesth. 2011 Dec;107 Suppl 1:i60-71. |
38. Lien CA. A need to establish programs to detect and prevent drug diversion. Mayo Clin Proc. 2012 Jul;87(7):607-9. PMCID: PMC3498429 |
39. Rathmell JP, Lien C, Harman A. Objective structured clinical examination and board certification in anesthesiology. Anesthesiology. 2014 Jan;120(1):4-6. |
40. Lien CA, Kopman AF. Current recommendations for monitoring depth of neuromuscular blockade. Curr Opin Anaesthesiol. 2014 Dec;27(6):616-22. |
41. Sun H, Culley DJ, Lien CA, Kitchener DL, Harman AE, Warner DO. Predictors of performance on the Maintenance of Certification in Anesthesiology Program® (MOCA®) examination. J Clin Anesth. 2015 Feb;27(1):1-6. |
42. Fleischut PM, Eskreis-Winkler JM, Gaber-Baylis LK, Giambrone GP, Wu X, Sun X, Lien CA, Faggiani SL, Dutton RP, Memtsoudis SG. Provider Board Certification Status and Practice Patterns in Total Knee Arthroplasty. Acad Med. 2016 Jan;91(1):79-86. PMCID: PMC4826752 |
43. McEvoy MD, Lien CA. Education in Anesthesiology: Is It Time to Expand the Focus? A A Case Rep. 2016 Jun 15;6(12):380-2. |
44. Hawkins RE, Irons MB, Welcher CM, Pouwels MV, Holmboe ES, Reisdorff EJ, Cohen JM, Dentzer S, Nichols DG, Lien CA, Horn TD, Noone RB, Lipner RS, Eva KW, Norcini JJ, Nora LM, Gold JP. The ABMS MOC Part III Examination: Value, Concerns, and Alternative Formats. Acad Med. 2016 Nov;91(11):1509-1515. |
45. Sun H, Zhou Y, Culley DJ, Lien CA, Harman AE, Warner DO. Association between Participation in an Intensive Longitudinal Assessment Program and Performance on a Cognitive Examination in the Maintenance of Certification in Anesthesiology Program®. Anesthesiology. 2016 Nov;125(5):1046-1055. |
46. Heerdt PM, Sunaga H, Owen JS, Murrell MT, Malhotra JK, Godfrey D, Steinkamp M, Savard P, Savarese JJ, Lien CA. Dose-response and Cardiopulmonary Side Effects of the Novel Neuromuscular-blocking Drug CW002 in Man. Anesthesiology. 2016 Dec;125(6):1136-1143. |
47. Lien CA, Warner MA, Rathmell JP. Simulation for Assessment of the Practice of Board-certified Anesthesiologists. Anesthesiology. 2017 Sep;127(3):410-412. |
48. Zhou Y, Sun H, Lien CA, Keegan MT, Wang T, Harman AE, Warner DO. Effect of the BASIC Examination on Knowledge Acquisition during Anesthesiology Residency. Anesthesiology. 2018 Apr;128(4):813-820. |
49. Lien CA. If Only the Practice of Evidence-Based Medicine Was as Simple as Creating Guidelines…. Anesth Analg. 2018 Jul;127(1):9-11. |
50. Warner DO, Zhou Y, Keegan MT, Lien CA, Sun H. In Reply. Anesthesiology. 2018 Dec;129(6):1191-1192. |
51. Bustillo MA, Lien CA, Mack PF, Kopman DJ, Safavynia SA, Rubin L, Stein D, Hartl R, Stieg PE, Hernandez RN, Goldstein PA. Optimizing Patient Access During an Emergency While Using Intraoperative Computed Tomography. World Neurosurg. 2019 Jan;121:274-278.e1. |
52. Haskins SC, Feldman D, Fields KG, Kirksey MA, Lien CA, Luu TH, Nejim JA, Osorio JA, Yang EI. Teaching a Point-of-Care Ultrasound Curriculum to Anesthesiology Trainees With Traditional Didactic Lectures or an Online E-Learning Platform: A Pilot Study. J Educ Perioper Med. 2018;20(3):E624. PMCID: PMC6257000 |
53. Kaullen JD, Owen JS, Brouwer KLR, Heerdt PM, Lien CA, Savarese JJ, Schmith VD. Pharmacokinetic/Pharmacodynamic Model of CW002, an Investigational Intermediate Neuromuscular Blocking Agent, in Healthy Volunteers. Anesthesiology. 2018 Jun;128(6):1107-1116. PMCID: PMC5953789 |
54. Fahy BG, Culley DJ, Sun H, Dainer R, Lutkoski BP, Lien CA. Gender Distribution of the American Board of Anesthesiology Diplomates, Examiners, and Directors (1985-2015). Anesth Analg. 2018 Aug;127(2):564-568. |
55. Harman A, Tung A, Fox C, Lien CA. Heuristics, Overconfidence, and Experience: Impact on Monitoring Depth of Neuromuscular Blockade. Anesth Analg. 2019 Jun;128(6):1057-1059. |
56. Pagel PS, Freed JK, Lien CA. Gender Differences in Authorship in the Journal of Cardiothoracic and Vascular Anesthesia: A 28-Year Analysis of Publications Originating From the United States, 1990-2017. J Cardiothorac Vasc Anesth. 2019 Mar;33(3):593-599. |
57. Pagel PS, Freed JK, Lien CA. Gender Composition and Trends of Journal of Cardiothoracic and Vascular Anesthesia Editorial Board Membership: A 33-Year Analysis, 1987-2019. J Cardiothorac Vasc Anesth. 2019 Dec;33(12):3229-3234. |
58. Warner DO, Isaak RS, Peterson-Layne C, Lien CA, Sun H, Menzies AO, Cole DJ, Dainer RJ, Fahy BG, Macario A, Suresh S, Harman AE. Development of an Objective Structured Clinical Examination as a Component of Assessment for Initial Board Certification in Anesthesiology. Anesth Analg. 2020 Jan;130(1):258-264. |
59. Gonzalez LS, Fahy BG, Lien CA. Gender distribution in United States anaesthesiology residency programme directors: trends and implications British Journal of Anaesthesia. 2020. |
60. Warner DO, Lien CA, Wang T, Zhou Y, Isaak RS, Peterson-Layne C, Harman AE, Macario A, Gaiser RR, Suresh S, Culley DJ, Rathmell JP, Keegan MT, Cole DJ, Fahy BG, Dainer RJ, Sun H. First-Year Results of the American Board of Anesthesiology's Objective Structured Clinical Examination for Initial Certification. Anesth Analg. 2020 Jul 23. |
Books, Chapters, and Reviews |
1. Lien CA, Belmont MR, Kopman AF, Savarese JJ. What is really new about the new relaxants? Anesthesiology Clinics of North America. 1993;11(4):729-778. |
2. Rubin LA, Lien CA, Savarese JJ. Mivacurium: A novel, short-acting, nondepolarizing muscle relaxant Seminars in Anesthesia, Perioperative Medicine and Pain. December 1995;14(4):245-256. |
3. Lien CA, Savarese JJ. Neuromuscular junction pharmacology Foundations of Anesthesia. 2006:445-460. |
4. Bustillo M, Lien CA. Carotid endarterectomy Yao & Artusio's Anesthesiology: Problem-Oriented Patient Management: Seventh Edition. 18 January 2012:478-507. |
5. Swamidoss CP, Lien CA. Myasthenia gravis Yao & Artusio's Anesthesiology: Problem-Oriented Patient Management: Seventh Edition. 18 January 2012:1154-1167. |
6. Lien CA, Eikermann M. Neuromuscular Blockers and Reversal Drugs Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application. January 2013:325-348. |
7. Lien CA. Neuromuscular blocking and reversal agents Geriatric Anesthesiology: Third Edition. 27 October 2017:321-332. |
8. Lien CA, Eikermann M. Neuromuscular blockers and reversal drugs Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application. 1 January 2018:428-454. |
9. Naguib M, Lien CA, Meistelman C. . Pharmacology of muscle relaxants and their antagonists. Miller RD (ed), Anesthesia, 8th Edition. Churchill Livingston Elsevier, Philadelphia, PA. 2014, pp 958-994. |
10. Harman A, Lien CA. . The process of Board Certification Frost EAM (ed), Comprehensive Guide to Education in Anesthesia. Springer, NY. 2013, 99-116. |
11. Pamnani A, Lien CA, Rooke GA. . Pulmonary issues in the elderly patient. Barnett SR (ed), Manual of Geriatric Anesthesia, Springer Science +Business Media, New York. 2013, 217-233. |
12. Naguib M, Lien CA. . Pharmacology of muscle relaxants and their antagonists Miller RD (ed), Anesthesia 7th Edition. Churchill Livingston Elsevier, Philadelphia, . 2010, 589-914. |
13. Lien CA, Suzuki T. . Relaxants and Their Reversal Agents. Silverstein JH, Rooke GA, Reeves JG, McLesky CH (eds), Geriatric Anesthesiology, Second Edition. Springer, New York. 2008, 266-277. |
14. Swamidoss CP, Lien CA. . Myasthenia Gravis Anesthesiology: Problem Orientated Patient Management, 6th Edition. Lippincott Williams and Wilkins, Philadelphia. 2008, 1075-1090. |
15. Bustillo M, Lien CA. . Carotid Endarterectomy Yao F (ed). Anesthesiology: Problem Orientated Patient Management, 6th Edition. Lippincott Williams and Wilkins. Philadelphia. 2008, 548-576. |
16. Lien CA. . New neuromuscular blocking and reversal agents Hemmerling TM (ed), A Guidebook to Neuromuscular Transmission, Blockade and Monitoring for Anaesthesia and Intensive Care. Research Signpost, Kerala, India. 2007, 34-54. |
17. Naguib M, Lien CA. . Pharmacology of muscle relaxants and their antagonists Miller RD (ed), Anesthesia 6th Edition. Churchill Livingston, Philadelphia. 2005, 481-572. |
18. Lee M, Lien CA. . Anesthesia for carotid endarterectomy Yao F (ed), Anesthesiology: Problem Oriented Patient Management, 5th Edition. J.B. Lippincott Williams and Wilkins, Philadelphia. 2003, pp 530-556. |
19. Sousa MM, Lien CA. . Myasthenia gravis Yao F (ed), Anesthesiology: Problem Oriented Patient Management, 5th Edition. J.B. Lippincott Williams and Wilkins, Philadelphia. 2003, pp 1019-1032. |
20. Lien CA.. The pharmacology of GW280430A: A new nondepolarizing neuromuscular blocking agent. Seminars in Anesthesia, Perioperative Medicine and Pain.. 2002; 21:86-91. |
21. Lien CA, Savarese JJ. . Neuromuscular Junction Pharmacology. Hemmings HC and Hopkins (eds), Foundation in Anesthesia. Mosby International, London. 2000, pp 339-354. |
22. Savarese JJ, Caldwell J, Lien CA, Miller RD.. Pharmacology of Muscle Relaxants and their Antagonists Miller RD (ed), Anesthesia, fifth edition. Churchill-Livingstone, Philadelphia. 2000, PP 412-490. |
23. Lien CA, VanPoznak A. . Anesthesia for carotid endarterectomy Yao F and Artusio J (eds), Anesthesiology: Problem Orientation Patient Management, 4th edition. J.B. Lippincott Raven Publishers, New York. 1998, pp 455-481. |
24. Lien CA, VanPoznak A. . Myasthenia gravis Yao F and Artusio J (eds), Anesthesiology: Problem Orientation Patient Management, 4th edition. J.B. Lippincott Raven Publishers, New York. 1998, pp 867-877. |
25. Hill SA, Lien CA, Scott RPF, Savarese JJ. . Neuromuscular blocking drugs and their antagonists Brown BR and Prys-Roberts C (eds), International Practice of Anesthesia. Reed Educational and Professional Publishing LImited, Bath. 1996, pp 1/91/1/-1/91/41. |
26. Lien CA, Belmont MR, Rubin L, Savarese JJ. . Benzylisoquinoine compounds White PF (ed), Textbook of Intravenous Anesthesia. Volume 51. WB Saunders Company, Philadelphia. 1995: 245-256. |
27. Lien CA, Savarese JJ, Kopman AF. . Clinical pharmacology and applications of neuromuscular blockers Bowdle TA, Horita A, Kharasch ED (eds), The Pharmacologic Basis of Anesthesiology. Churchill Livingstong, New York. 1994, pp 439-482. |
28. Savarese JJ, Miller RD, Lien CA, Caldwell JE. . Pharmacology of muscle relaxants and their antagonists Miller Rd (ed), Anesthesia 4th Edition. Churchill Livingstone, New York. 1994, pp 417-487. |
29. Venketasuramian N, Mohr JP, Young WL, Lien CA, Breuer A. Anatomy and physiology of the vascular supply to the brain Downey JA, Myers SJ, Gonzalez EG, Lieberman JS (eds), The physiologic Basis of Rehabilitation Medicine, 2nd Edition. Butterworth-Heinemann Boston. 1994, pp 19-33. |
30. Lien CA, VanPoznak A.. Anesthesia for carotid endarterectomy Yao F and Artusio J (eds), Anesthesiology: Problem Oriented Patient Management, 3rd Edition. J.B. Lippincott Company New York. 1993, pp 338-361. |
31. Lien CA, VanPoznak A. . Myasthenia gravis Yao F and Artusio J (eds), Anesthesiology: Problem Oriented Patient Management, 3rd Edition. J.B. Lippincott Company New York. 1993, PP 633-643. |
32. Lien CA, Belmont MR, Kopman A, Savarese JJ. . The new muscle relaxants Barash P (ed), Anesthesia Refresher Courses. . Vol 21, 1993, pp 255-282. |
Editorials, Letters to Editor, Other |
1. Tung A, Harman A, Lien CA. In Response. Anesth Analg. 2019 Nov;129(5):e173. |
2. Kopman AF, Lien CA, Naguib M. Determining the potency of neuromuscular blockers British Journal of Anaesthesia. October 2010;105(4):544-545. |
3. Pryor KO, Lien CA, Fahey TJ 3rd, Goldstein PA. Supplemental oxygen and risk of surgical wound infection. JAMA. 2006 Apr 12;295(14):1642; author reply 1642-3. |
4. Hopf HW, Hunt TK, Rosen N. Supplemental oxygen and risk of surgical site infection. JAMA. 2004 Apr 28;291(16):1956; author reply 1958-9. |
5. Lien CA, Belmont MR, Heerdt PM. GW280430A: pharmacodynamics and potential adverse effects. Anesthesiology. 2005 Apr;102(4):861-2; author reply 862-3. |
6. Rathmell JR, Lien CA, Harman A. . In Reply to Kempen PM. Corporate interests necessitate conflict of interest declarations by all authors. Anesthesiology. 2014; 121:432. |
7. Naguib M, Kopman AF, Lien CA, Hunter JM, Brull SJ. . In Reply to Cerny V, Herold I, Cvachovec K, Sevcik, Adamus M. Guidelines for managing neuromuscular block: not only Czech beer deserves a taste. Anesth Analg . 2011; 112:482. |
8. Naguib M, Kopman A, Lien CA, Hunter JM, Brull SJ. . Newsletter readers invited to participate in survey on residual neuromuscular paralysis in PACU Anesthesia Patient Safety Foundation Newsletter. Summer 2008, 23:26. |
9. Lien CA. . Recovery from neuromuscular blockade: How much is enough? Anesthesia Patient Safety Foundation. Winter, 2001-2002; 16:61. |
10. Kelly RE, Lien CA. . Electromyographic and mechanomyographic neuromuscular effects of desflurane (response). Anesth Analg . 1994; 78:603. |
11. Warner DO, Lien CA, Wang T, Zhou Y, Isaak RS, Peterson-Layne C, Harman AE, Macario A, Gaiser RR, Suresh S, Culley DJ, Rathmell JP, Keegan MT, Cole DJ, Fahy BG, Dainer RJ, Sun H. First-Year Results of the American Board of Anesthesiology's Objective Structured Clinical Examination for Initial Certification. Anesth Analg. 2020 Nov;131(5):1412-1418. |
12. Lien C, Raimo J, Abramowitz J, Khanijo S, Kritharis A, Mason C, Jarmon CH, Nash IS, Carney MT. Community healthcare delivery post-Hurricane Sandy: lessons from a mobile health unit. J Community Health. 2014 Jun;39(3):599-605. |
13. Kirsch JR, Lien CA. Evolving Neuroanesthesia Practice. Anesthesiol Clin. 2021 Mar;39(1):xv-xvi. |
14. Gaulton TG, Neuman MD, US intubateCOVID Investigators. Trends in personal protective equipment use by clinicians performing airway procedures for patients with coronavirus disease 2019 in the USA from the intubateCOVID registry. Br J Anaesth. 2021 May;126(5):e184-e186. PMCID: PMC8052559 |
15. Warner DO, Lien CA, Wang T, Zhou Y, Isaak RS, Peterson-Layne C, Harman AE, Macario A, Gaiser RR, Suresh S, Rathmell JP, Keegan MT, Cole DJ, Fahy BG, Dainer RJ, Sun H. In Response. Anesth Analg. 2021 Jul 01;133(1):e5-e7. |
16. Grivoyannis AD, Tangel V, Lien CA. Vigilance: the behavioral impact of quantitative monitoring on administration and antagonism of neuromuscular blocking agents Journal of Clinical Monitoring and Computing. 2021. |
17. Grivoyannis AD, Tangel V, Lien CA. Vigilance: the behavioral impact of quantitative monitoring on administration and antagonism of neuromuscular blocking agents. J Clin Monit Comput. 2022 Aug;36(4):1043-1051. |
18. Lien CA, Savarese JJ. Neuromuscular Junction Pharmacology Foundations of Anesthesia: Basic Sciences for Clinical Practice. 2 November 2005:445-460. |
19. Sunaga H, Lien CA. Development of New Neuromuscular Blocking Agents Current Anesthesiology Reports. June 2013;3(2):105-113. |
20. Thilen SR, Weigel WA, Todd MM, Dutton RP, Lien CA, Grant SA, Szokol JW, Eriksson LI, Yaster M, Grant MD, Agarkar M, Marbella AM, Blanck JF, Domino KB. 2023 American Society of Anesthesiologists Practice Guidelines for Monitoring and Antagonism of Neuromuscular Blockade: A Report by the American Society of Anesthesiologists Task Force on Neuromuscular Blockade. Anesthesiology. 2023 Jan 01;138(1):13-41. |
Non-Refereed Journal Publications/Original Papers |
1. Lien CA. The pharmacology of GW280430A: A new nondepolarizing neuromuscular blocking agent Seminars in Anesthesia Perioperative Medicine and Pain. 2002;21(2):86-91. |
2. Lien CA. The role of stereoisomerism in neuromuscular blocking drugs Current Opinion in Anaesthesiology. 1996;9(4):348-353. |
3. Lien CA. Profound Neuromuscular Blockade: Advantages and Challenges for Patients, Anesthesiologists, and Surgeons. Current Anesthesiology Reports. 2018;8:161-7. |
4. Lien CA, Rathmell JP. . ABA MOCS 2.0: A Pathway to Professionalism ASA Monitor. 2016;80:14-17. |
5. Lien CA.. Standing my Ground: Memoir of a Woman Physician. Book Review, Anesthesiology. 2015;123:737-738. |
6. Sunaga H, Lien CA.. Development of new neuromuscular blocking agents. Current Anesthesiology Reports. 2013:3:105-13. |
7. Kopman D, Lien CA. . Physiology and pharmacology of neuromuscular transmission: New developments that may change your practice. ASA Refresher Courses in Anesthesiology. Lippincott Williams and Wilkins, Philadelphia, PA. 2009:37:107-117. |
8. . Neuromuscular transmission: New developments that may change your practice. 59th Annual Refresher Course Lectures. 2008. |
9. Lien CA. . The neuromuscular junction: Pharmacologic applications during anesthesia. Anesthesiology 58th Annual Refresher Course Lectures. 2007. |
10. Lien CA. . The neuromuscular junction: Pharmacologic applications during anesthesia. Anesthesiology 57th Annual Refresher Course Lectures. 2006. |
11. Lien CA. . The neuromuscular junction: Pharmacologic applications during anesthesia. Anesthesiology: ASA Refresher Courses in Anesthesiology Lippincott Williams and Wilkins, Philadephia, PA. . 2005;275:1-6. |
12. Lien CA. What's new in Muscle Relaxant Development? The North Carolina Society of Anesthesiologists Newsletter. Vol. 13, Spring 2004, 4-7. |
13. Lien CA, Fogarty Mack P. . The effect of anesthesia on thermoregulation in the elderly patient. Current Anesthesiology Reports. 2000;6:473-481. |
14. Lien CA. . Thermoregulation in the Elderly. Syllabus on Geriatric Anesthesiology. ASA Subcommittee on Geriatric Anesthesiology. Version 7/13/01. |
15. Lien CA. . Use of Nondepolarizing Neuromuscular Blocking Agents in the Elderly. Syllabus on Geriatric Anesthesiology. ASA Subcommittee on Geriatric Anesthesiology. Version 7/13/01. |
16. Lien CA. Rational use of muscle relaxants, in: IARS 1994 Review Course Lectures. Anesthesia & Analg suppl. pp 66-72. |
Abstracts |
1. Pagel PS, Freed JK, Lien CA. A 50-year analysis of gender differences in United States authorship of original research articles in two major anesthesiology journals Scientometrics. 2019. |
2. Kaullen J, Owen J, Brouwer K, Heerdt PM, Lien CA, Savarese JJ, Schmith VD.. Pharmacokinetic/Pharmacodynamic (PK/PD) Model of CW002, an Investigational Intermediate Neuromuscular Blocking (NMB) Agent in Healthy Volunteers American Society of Clinical Pharmacology and Theraputics. 2017. |
3. Grivoyannis A, Tangel V, Tope CP, Lien CA. . The Impact of Quantitative Monitoring on Dosing and Antagonism of Residual Neuromuscular Block. 2016 Annual Meeting of the American Society of Anesthesiologists, Chicago, IL. October, 2016. |
4. Sun H, Zhou Y, Culley D, Lien CA, Harman Ae, Post M, Warner DO. . Reimagining MOC: Innovation in knowledge assessment to support lifelong learning. 2016 ABMS Workshop on Adult Learning. Cleveland, OH. September 2016. |
5. Turnbull ZA, Tangel V, Alexander MJ, Chan C, Lien CA, Ivascu N. . Timing and outcomes of permanent pacemaker placement after aortic valve replacement. Association of University Anesthesiologists, 63rd Annual Meeting San Francisco, CA. 2016, Clinc OC 95 (105) . |
6. Owen JS, Heerdt PM, Malhotra JK, Murrell MT, Trepainer NM, Lien CA. . Pharmacokinetics of CW002, a novel neuromuscular blocking agent in the initial cohorts of a Phase 1 clinical trial. American Association of Pharmaceutical Scientists, San Antonio, TX. November 14, 2013, AM-13-2771. |
7. Murrell MT, Malhotra J, Sunaga H, Savard P, Godfrey D, Heerdt P, Lien CA. . potency and preliminary pharmacodynamics of the novel neuromuscular blocking drug CW002 in humans during sevoflurane/nitrous oxide anesthesia. ASA, San Francisco, CA. 2013, LBB03. |
8. Malhotra J, Owen J, Murrell M, Sunaga H, Savard H, Godfrey D, Heerdt P, Lien C. . Preliminary pharmacokinetics of the novel neuromuscular blocking drug CW002 in humans during sevoflurane/nitrous oxide anesthesia. ASA, San Francisco, CA. 2013, LBB04. |
9. Murrell MT, Malhotra J, Sunaga H, Heerdt PM, Lien C. . First use of the novel neuromuscular blocking drug CW002 in man: Single dose pharmacodynamic assessment during Propofol or sevoflurane anesthesia. IARS, San Diego, CA. 2013, S-50. |
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